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Calibrated Input File (LPL)
Human Bladder Carcinoma Cells

/*
  LPL Model Input File for Human Bladder Carcinoma Cells (RT112)
  REFERENCE:
      Ruiz de Almodovar JM, Bush C, Peacock JH, Steel GG, Whitaker SJ, McMillan TJ.
      Dose-rate effect for DNA damage induced by ionizing radiation in human tumor
      cells. Radiat. Res. 138, S93-S96 (1994)
  PREPARED BY: RD STEWART (trebor@purdue.edu)
  DATE: 14-JUL-2003
*/
   MODEL: DRM=LPL CKM=QECK         !Model Specification
   CELL: DNA=5.667D+09 NC=46
   IRAD: CL=25 FL=1.5962890E-01
   CLRP: RHT=2.2111258E-01 BMR=1.1125463E-03 GAM=0.25 A0=0.95
   CCKM: TCC=10 TPOT=20 GF=0.0 N0=1 KAP=1.0D+38 VOL=1
   RBM: KX=6.0E+06 FMAX=1   !Analysis of PFGE data
!  Parameters that impact on solution accuracy
   SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10
!  Parameters that control the time steps and stopping criteria
   SIMCON: FSDX=1 TSAX=12 TCUT=96 FRDL=1.0D+00 RCUT=1.0D-09
 !IRRADIATION CONDITIONS (single fraction)
  RADX: ADR=RX1 AD=RX2
  RX1 = 0.6 1.2 3.0 6.0 12 30 76.8 /  !dose rate (Gy/h)
  RX2 = 0 0.1 0.25 0.5 1 1.5 2 3 4 5 6 7 8 9 10
        12.5 15 17.5 20 25 30 35 /

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