MODEL: DRM=TLK CKM=QECK
   CELL: DNA=5.667D+09 NC=46
   IRAD: CL=DSB
   CLRP: RHT=HT4R BMR=2.75E-04 PHI=PML A0=PMR
   CCKM: TCC=10 TPOT=20 GF=0.0 N0=1 KAP=1.0D+38 VOL=1
   RBM: KX=6.0E+06 FMAX=1   !Analysis of PFGE data

!  TLK model inputs (simple and complex double strand breaks)
   DSB = 20 5 /           !Radiation damage to DNA
   HT4R = 0.25 7 /        !Half-times for DSB repair
   PML = 0.01 /           !Probability a misrejoined DSB is lethal
   PMR = 0.75 0.25 /      !Probability DSB is rejoined correctly

!  Parameters that impact on solution accuracy
   SOLVER: DBLV=0 ETOL=1.0E-09 MXSS=999999 HMAX=10

!  Parameters that control the time steps and stopping criteria
   SIMCON: FSDX=1 TSAX=12 TCUT=96 FRDL=1.0D+00 RCUT=1.0D-09

   BCONF: MITR=10000 MXFN=100000 SGT=1.0D-04 SST=1.0D-09 FCT=1.0D-09
   MCAT: NPAR=4 
   AMP1: CID=CLRP PNAM=BMR PLB=0.0 PUB=1.0D-02 PIG=2.0E-04
   AMP2: CID=CLRP PNAM=PHI PLB=0.0 PUB=0.25 PIG=0.01 LI=0       
   AMP3: CID=CLRP PNAM=RHT PLB=0.01 PUB=12 PIG=0.15 LI=1        
   AMP4: CID=CLRP PNAM=RHT PLB=0.01 PUB=12 PIG=8 LI=2           
   AMP5: CID=IRAD  PNAM=CL PLB=1 PUB=20.0 PIG=5 LI=2          

/*
  Figure of Merit (FOM) Weight
  1: cell survival data
  2: DSB rejoining data (FAR)
  3: DSB rejoining data (Avg. DSB/cell)
  4: Transformed cells per survivor
  5: Transformed cells per irradiated cell
 */
  FOM: UW=LFWT
  LFWT = 1 0 0 0 0 /

Last updated: 10 June, 2011
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