TODD L. RICHARDS

1. Personal Data:

Citizenship: US

Business address:

Department of Radiology, Box 357115

University of Washington

Seattle, WA 98195

Phone: (206-616-0015)

email: toddr@u.washington.edu

2. Education

Ph.D.; Biophysics-Neuro, University of California, Berkeley, Sept. 1984

B.S.; Physics, Brigham Young University, Aug. 1979

Thesis title: NMR imaging and spectroscopy of the mammalian central nervous system after heavy ion radiation.

Thesis committee members: Thomas F. Budinger, Cornelius Tobias, Paola Timiras

3. Faculty Positions Held:

Professor, Radiology, University of Washington, 1998-present

Associate Professor, Radiology, University of Washington, 1991-1998

Adjunct faculty, Bioengineering, Univ. of Wash., 1990-present

MRI consultant, Marion Merrell Dow Inc, Kansas City, MO, 1991-1993

Assistant Professor, Radiology, University of Washington, 1985-1991

Affiliate, Regional Primate Center, University of Washington, 1986-1994

Affiliate, Bloedel Hearing Research Center, 1992-present

Affiliate, CDMRC, 1993- present

Consultant for chemical shift imaging, Diasonics Inc., 1984-85

Post. Doc.; Hounsfield Research Fellow (NMR Res. Physicist); UCSF, 1984-85

4. Postgraduate Training:

Post-Doc; NMR spectroscopy, University of California, San Francisco, 1985

Post. Doc.; Hounsfield Research Fellow (NMR Res. Physicist); UCSF, 1984-85

5. Honors:

I was invited to be a member of the American Institute of Biological Sciences Scientific Peer Advisory & Review Services

Invited to NIH Study Section: Language and Communications (LCOM), February 2018

5. Professional Organizations:

International Society for Magnetic Resonance in Medicine

Human Brain Mapping

Cognitive Neuroscience Society

5. Teaching Responsibilities:

Students Supervised:

Rebekah Petroff. Graduate Student, 2018 -ongoing

Jo-Fu Lotus Lin, Graduate Student, Department of Speech and Hearing, PhD committee, 2005-2009

Leah Altemier, Graduate Student, Education, Dyslexia, 2003-2007

Allison Brooks, Graduate Student, Education, Neuroimaging, 1999-2004

KC Stegbauer, Graduate Student, Bioengineering, MR spectroscopy, 1997-present

Sandra Serafini, graduate student, Department of Speech and Hearing, Thesis advisor, 1995- present

Brenden Boys, undergraduate, 1997.

Jilma Jimenez - visiting student, Bioengineering, Wright State University, 1993 - 1998

Katrin Petersen - undergraduate student - 1993 - 1996

Lori Arakaki- Bioengineering, An optical method for myoglobin oxygenation measurements in the blood-perfused rat hind limb, Ph.D. Thesis committee, 1991 - 1995

Wayne Strauss - medical student/ bioengineering -1993 - 1999

Aaron Heide - Medical student, Diffusion imaging of experimental allergic encephalomyelitis, 1991- 1999

Ken Marro - Bioengineering, Lactate signal attenuation due to coherent flow in volume-localized proton spectroscopy, 1991-1996

Dan Leotta - Qualifying exam committee, 1993

Alan DeSoto - Electrical Engineering, Stereotaxic MR image registration.,1993

Ian Sweet - Bioengineering, P-31 spectroscopy of muscle in Diabetes, Ph.D., 1990.

Alex Hertzberg - Bioengineering, Measurement of Bone Trabeculae and bone marrow with MRI, Ph.D. , 1990

Don Allen, Electrical Engineering, Computer software for NMR spectral analysis, 1989.

Courses Taught:

Lecture given to PET physics group, UW on April 23, 2009 on Advances in MR imaging

Lecture given to Neuroradiology group, UW on March 24, 2009 on Advances in MR Neuroimaging techniques

Bioeng 565/Radgy 550, NMR in Biomedicine, Winter quarter 1995, 1997, 1999, 2001, 2003, 2005 (Richards, PI)

Summer Basic MR physics course for radiology residents and staff, 1992 - 1999

Bioeng 599 I, NMR in Biomedicine, Winter Quarter 1993

Bioeng 599 H, NMR in Biomedicine, Spring Quarter 1992

RADGY 550/Bioengineering 599H spring 1991. MR physics

RADGY 550, Spring 1989, Spring 1990. In vivo NMR in Biomedicine. Team taught with Dr. Grant Steen.

MR physics taught to Radiology residents, 1986-present

"Biophysical Interpretation of MRI Image Intensity" as part of course on Magnetic Resonance Imaging: Its function and promise, Radiology Northwest, January 25, 1986.

8. Editorial Responsibilities:

National Correspondent, International Journal of Neuroradiology

Constant Reviewer, Magnetic Resonance in Medicine

Constant Reviewer, Human Brain Mapping

9. Special National Responsibilities:

American Institute of Biological Sciences Scientific Peer Advisory & Review Services 1900 Campus Commons Drive, Suite 200 Reston, VA 20191

NIH Study Section, LANGUAGE AND COMMUNICATION STUDY SECTION 2008

10. Special Local Responsibilities Local Responsibilities:

UW Faculty Senator - 1989 - 1991

UW Faculty Senator – 2002 - 2003

11. Research Funding

Current Research Support

5 P50 HD 071764-03 (Berninger) 12/15/11 – 11/30/16 with nocost extention 2017

Defining and Treating Written Language Disabilities

There are seven broad objectives: (1) Use learning profiles of writing, reading, and oral langauge skills to Identify clear, non-overlapping cases of 3 well-defined specific learning disabilities in written language (SLDs-WL); (2) Investigate studetns (ages of 10-15 years old) who do and do not struggle in learning written language; (3) Examine whether the brain’s temporal functional connectivity differs; (4) Increase knowledge of why some students show persisting difficulties; (5) Inhance knowledge of whether phenotypic, genetic and motivation factors predict behavioral RTI and brain RTI for students in general; (6) Evaluate which of the variables in Objective 5 best predicts behavioral RTI and brain RTI for each of the SLDs-W; (7) Share the instrcution for students, teachers and the community.

Role: Co-PI, PI of Project 3

5 R01 HD 073128-02 (Juul) 6/1/2013-5/31/2018

Biomarkers of neonatal encephalopathy in a nonhuman primate model

The goal of this project is 1. to develop sensitive and specific diagnostic early biomarkers of severity of acute brain injury, 2. to develop early prognostic biomarkers of long term outcomes of HIE, using sequential evaluations of the proteome and metabolome and MRI/MRS to correlate individual acute response to injury with long-term structural and functional outcomes, and 3. to develop predictive biomarkers of individuals response to therapy.

Role: Co-Investigator

5U01NS077953‐02 (Juul) 6/1/2013-5/31/2018

Preterm Epo Neuroprotection Trial (PENUT Trial) CCC

Our specific aims are: 1) determine whether Epo decreases the combined outcome of death or NDI at 24-26 months post menstrual age (PMA). NDI is defined as the presence of any one of the following: CP, Bayley III Scales of Infant and Toddler Development mental developmental index (MDI) < 70, or psychomotor developmental index (PDI) < 70. CP will be identified, sub-typed, and categorized by standardized neurologic exam; 2) determine whether there are risks to Epo administration in ELGANs by examining, in a blinded manner, Epo-related safety measures comparing infants receiving Epo with those given vehicle; 3) test whether Epo treatment decreases serial measures of circulating inflammatory mediators, and biomarkers of brain injury; 4) determine whether Epo treatment improves brain structure (volume of gray matter, white matter and cerebellum, brain gyrification, and tract-based spatial statistics) at 36 weeks PMA as measured by MRI.

Role: Co-Investigator

5R01MH104313 (Kleinhans, Natalia M) 8/15/14-5/31/19

Molecular mechanisms of atypical habituation in autism spectrum disorders

The major goal of this project is to determine if there is a link between atypical amygdala habituation and GABAergic dysfunction in ASD.

Role: Co-investigator

I01CX001049 (Peskind/Petrie) 10/1/13 – 9/30/17

Multimodal Biological Assessment of Gulf War Illness

The major goals of this project are to identify in Gulf War Veterans' Illness abnormalities in brain structural and functional integrity; abnormalities in central and peripheral systems regulating pain perception, fatigue, and sleep; and to identify genetic variants and/or epigenetic alterations associated with neurodegeneration, impaired pain processing, and metabolism of organophosphates.

Role: Co-Investigator

SMA-0835854 AM04 (Kuhl) 10/01/2009 – 1/31/17

Learning and Informal & Formal Environments

The LIFE Center (Learning in Informal and Formal Environments) is focused on the social foundations of learning in informal and formal settings from infancy through adulthood. Our Purpose as follows:

To develop and test principles about the social foundations of human learning in informal and formal environments with the goal of enhancing human learning from infancy to adulthood

Role: Co-Investigator

On most of these projects above, I am the main MR expert incharge of both MR acquistion and analysis.

Past Research Support:

5 P50 HD 055782-04 (DAGER)	8/1/07 – 7/31/12	3 calendar
NIH (NICHD)	$1,523,455
UW Autism Center of Excellence
The specific aims of this project are: (1) Identification of early risk indices for autism. As an extension of our earlier work, we seek to discover early risk indices for autism that can be detected in infants, including genetic/familial, brain structural/chemical, neurophysiological, and behavioral indices, that can increase our ability to identify infants who will eventually develop autism or autism-related symptoms. (2) Development of effective intervention methods for infants and toddlers. We plan to conduct two studies examining the efficacy of novel early interventions for infants and toddlers with autism or autism-related symptoms. (3) Understanding variation in outcome and adaptation in autism. Role: Co Investigator

R01HD052820-01A2 (Juul)	9/17/07-6/30/12	1.80 calendar
NIH/NICHD	$450,279 ADC
Optimizing Neuroprotection Following Perinatal Asphyxia
The major goals of this project are to develop an approach to perinatal asphyxia that will decrease the neurologic injury sustained from lack of oxygen to the brain, thereby helping affected children achieve their full potential and lead healthy and productive lives. Role: Co-Investigator Role: Co Investigator

1R01DA026438-01A109 (Sharar)	7/01/09-5/31/14	0.9 calendar
NIH	$250,000
Identifying Virtual Reality Analgesia Mechanisms by Pharmacologic Manipulation
We propose a series of studies in the laboratory pain setting (thermal and/or electrical pain in healthy volunteers) designed to test three specific and related hypotheses exploring the neurophysiologic mechanisms (functional MRI) that underlie immersive Virtual Reality (VR) as a non- pharmacologic pain management technique. Role: Co-Investigator

R01CA065537-15 (Eary)	8/14/06-6/30/12	1.2 calendar
NIH (NCI)	$234,386
PET in Sarcoma – A Clinical Trial
The overall goal of this project is to perform prospective imaging studies on patients to determine their tumor metabolism for identification of treatment response, and the ability of these measures to predict outcome. Role: Co Investigator

1RC4NS073008-01 (Grabowski)	9/1/10 – 8/31/13	1.2 calendar
NIH	$1,038,801
IBIC: Integrated Brain Imaging Center for the University of Washington
The specific aims of this is to accelerate collaboration and a new model for multidisciplinary interaction across cognitive neuroscience, human neuroimaging and medicine at the University of Washington. Role: Co-Investigator

SMA-0835854 AM04 (Kuhl)	10/01/09 - 01/31/15	2.40 calendar
NSF	$4,723,992
Learning and Informal & Formal Environments
The LIFE Center (Learning in Informal and Formal Environments) is focused on the social foundations of learning in informal and formal settings from infancy through adulthood. Our Purpose as follows: To develop and test principles about the social foundations of human learning in informal and formal environments with the goal of enhancing human learning from infancy to adulthood Role: Co-Investigator

5R33AG031485-03 (Unadkat)	01/01/12 - 03/31/12	0.6 calendar
NIH- Aging	$319,693.00
P-GLYCOPROTEIN AND ALZHEIMER'S DISEASE
DESCRIPTION (provided by applicant): To compare P-gp activity at the BBB in Alzheimer patients and in age-matched cognitively normal volunteers (controls), using the non-invasive technology, positron emission tomography (PET). Our studies will utilize an innovative, noninvasive PET imaging technique, developed by our laboratories, to measure P-gp activity at the BBB of patients with AD and age-matched cognitively normal volunteers. The logical progression of our studies from published data to in vivo studies in AD patients will unequivocally determine if P-gp activity is compromised in AD. These proposed studies have the potential to result in identification of P-gp as a novel therapeutic target for the treatment of AD, a disease for which no effective therapy exists. Role: Co-Investigator
2R01EY014645-07 (Fine)	01/01/12 - 08/31/16	0.6 calendar
NIH-NATIONAL EYE INSTITUTE	$358,244.00
EFFECTS OF BLINDNESS ON HUMAN EARLY VISUAL PATHWAYS
We propose to use a combination of "state-of-the-art" MR imaging techniques (high resolution structural imaging, probabilistic diffusion tractography, and magnetic resonance spectroscopy) to examine the effects of blindness on early stages of visual processing. This work is likely to have significance not only for our understanding of the development of the human visual system, but also for improving our general understanding of large scale sub-cortical and cortical plasticity. Role: Co-Investigator

(Berninger)	7/1/12 – 6/30/17	2.40 calendar
NIH	$1,199,815
Defining and Treating Written Language Disabilities
There are seven broad objectives: (1) Use learning profiles of writing, reading, and oral langauge skills to Identify clear, non-overlapping cases of 3 well-defined specific learning disabilities in written language (SLDs-WL); (2) Investigate studetns (ages of 10-15 years old) who do and do not struggle in learning written language; (3) Examine whether the brain’s temporal functional connectivity differs; (4) Increase knowledge of why some students show persisting difficulties; (5) Inhance knowledge of whether phenotypic, genetic and motivation factors predict behavioral RTI and brain RTI for students in general; (6) Evaluate which of the variables in Objective 5 best predicts behavioral RTI and brain RTI for each of the SLDs-W; (7) Share the instrcution for students, teachers and the community. Role: PI of Project 3

Eleven years of Continuous Support from NIH/NINDS

NIH- NINDS

NIH-RO1 NS-30722 (PI -Richards) 5/1/95 - 4/30/99

Multiple Sclerosis-- MR spectroscopy and evoked potentials

The major goal of this project is to correlate MR spectroscopy with visual and

somatosensory evoked potentials in patients with multiple sclerosis.

3. 5R21HD049832-02 (Valilala) 7/1/05-6/30/09

NIH/NICHD $275,000

Cerebral Edema in Pediatric Diabetic Ketoacidosis

The overall goals of this study are to characterize cerebrovascular changes in children critically ill with DKA, and to determine the relationship between laboratory markers, cerebrovascular changes and the presence or absence of cerebral edema.

Role: Co-investigator

High Q Foundation (Aylward) 6/1/06-08/1/08

Direct Cost for all years $422,938

Metabolic Spectroscopy as a Biomarker in Huntington’s Disease

Subjects with Huntington’s Disease and controls are scanned twice with MR spectroscopy, DTI, and structural scans to understand disease progression.

Role: Co-investigator

NIH/NICHD P50 33812 (PI, Berninger) 03/01/96 - 11/30/06

Learning Disabilities: Links to Schools and Biology

The major goal of this project is to use MR spectroscopy and functional MRI to study brain-

language activation in children with learning disabilities.

Role: PI of Project 4

Santa Fe Institute SFIC-W-01 (PIs, Kuhl, Meltzoff)                   3/1/02 - 12/31/03

    Santa Fe Institute Consortium (SFIC): Increasing Human Potential

The major goals of this project are to acquire a solid understanding of both the neurobiological and neuropsychological development of the normal human brain, with a particular emphasis on cognition, memory, and language as well as emotion and social interactions, and to use these insights to develop tools to enhance the home and educational environments of infants and adolescents, thereby optimizing plastic changes at these critical times in maturation and ultimately enhancing and improving intellectual capacity.

Role: Co-investigator

NIH/NINDS 1RO1 NS 36524 (PI Marra) 4/1/97-3/31/00

In vivo proton MRS studies of cerebral injury in HIV

dementia

This project will use proton MR spectroscopy to measure brain chemicals

such as NAA, choline, and myoinositol and correlate these with

clinical disability in patients with HIV dementia

NIH/NIMH 1 R21 MH63647-01 (PI- Marra) 5/1/01-3/31/04

Title: Novel Methods to Assess Brain Function in HIV-1

This is a pilot study to estimate the magnitude of changes in brain activation as measured by

functional MRI and functional MRS and by neuropsychological test performance in response to

potent antiretroviral therapy in HIV-1-infected individuals. A memory task is used during the

functional brain imaging.

Role: Co-Investigator

NIH 1 R21 HD040954-01 (PI Shara) 8/1/2001 - 7/31/2004

Title: Virtual Reality Analgesia for Rehabiliation in Children

The goal of these investigations is to develop non-pharmacologic analgesic techniques for subjects with subacute and chronic rehabilitation-induced pain (e.g., postburn physical therapy, rehabilitation activities following spinal cord injury, limb loss, and cerebral palsy), emphasizing virtual reality analgesia, the combination of virtual reality and hypnotic analgesia, and the analgesic mechanisms of these techniques.

Role: Co-Investigator

NIH - 5R01AA012915-02 (PI – Astley) 10/1/2002 – 9/30/2005

Title: MRI/S in Children with Prenatal Alcoholic Exposure

This project is to use MR spectroscopy and fMRI to study brain chemistry and brain activation in

children with fetal alcohol syndrome (FAS).

Role: Co-Investigator

NIH/NICCAM R21 AT00287-01 (PI Standish) (8/1/2000 - 7/31/2002)

Richards is PI at the UW site

Title: Transfer of neural energy between human subjects

This project will use functional MRI and electroencephalography to study brain activation

in humans during an energy transfer technique.

Subcontract with the University of Texas, Houston (PI Richards) 8/1/99-10/30/2002

Serial MRSI: Sub-study of Primary Progressive Multiple Sclerosis

This project will use proton MR spectroscopic imaging as an outcome measure

during a clinical trial to test the effectiveness of copaxone in primary progressive

multiple sclerosis

Subcontract with EDMS, LLC (PI Richards) 7/16/2000 - 6/15/2001

MR Imaging and Spectroscopy Evaluation for the Procarin Trial

This project uses proton MR spectroscopy and conventional MRI to evaluate changes in brain

chemistry and structure during the Procarin clinical trial for multiple sclerosis.

Multiple Sclerosis Association of America 5/1/97 - 7/15/98

Title - Evaluation of a pulsed electromagnetic therapy (Enermed) on Multiple Sclerosis

Patient Symptoms and Quality of Life

PI - T. Richards

The primary purpose of this research is to test the effects of a novel

electromagnetic treatment on physical function, cognitive function,

and quality of life experienced by MS sufferers.

Higher Ground for Humanity (PI- Richards) 9/16/98 - 9/15/99

Neurofeedback and bioelectric measurements in multiple sclerosis

This project will measure the effect of neurofeedback training in multiple

sclerosis patients

NIH R01 MH50579 (Dager) 1 0/1/94 - 9/30/97 20%

NIH/NIMH

MRS investigation of lactate-induced panic

The major goal of this project is to use proton MR spectroscopy to

study lactate infusion in panic patients.

NCI

NMR assay of thiol redox predicts tumor therapy response

PI - K Krohn

Coinvestigator - T Richards, 5%

period of support - May 1, 1992 - April 31, 1996

Source: Confidential Drug Company

Title: Phase 1 safety and pharmacokinetic study of Huf2G in subjects with multiple sclerosis

PI - James Bowen, M.D.

Period of Support: 10/94 - present

Role on the project: Co-investigator, 5%

National Multiple Sclerosis Society

Total brain n-acetyl imaging in multiple sclerosis

PI - T Richards, 10% time and salary

period of support - October 1, 1993 - September 31, 1995.

Royalty Research Fund

Functional and biochemical changes in sudden sensorineural hearging loss as measured by MRI and MRS

PI - T Richards

Period of support - Feb 1, 1994 - Jan 31, 1995

National INST of neurological disorders and stroke

MR evaluation of a model of multiple sclerosis

R01 NS30722-01

PI - T Richards,

period of support - April 1, 1992 - March 31, 1995

Priority percentile - 3.9

NIH

Axonal study for improved selective nerve anesthesia

PI - R. Fink

Consultant - T Richards

period of support 1991-1994

Bloedel Hearing Research Center

Magnetic resonance imaging of auditory nuclei in the chick brain

PI - T Richards

period of support - May 1, 1992 - April 31, 1993

First investigator grant from NINDS

Title of grant: "NMR spectroscopy of Demyelination in the Primate Brain"

R29 NS24622-01

PI - TL Richards

Period of support - April 1, 1987 - March 31, 1992

Priority percentile - 5

DOE INEL subcontract no. C85-110744,

Title of grant: "Boron NMR of tumors"

PI- TL Richards, 10% time and salary

Title of program project - "Neutron Capture Therapy: Brain Cancer Treatment Program Plan", PI - Merle L. Griebenow,

Period of support - October 1, 1987 - September 30, 1990

National Cancer Institue of NIH

Title of program project: Metabolic Imaging of Cancer and its Response to Therapy

Program director: Kenneth Krohn

Period of support - May 1, 1989 - April 30, 1994

Title of Project - Core G - NMR support

PI - Martin Kushmeric

Co-investigator - TL Richards, 5% time

RFA NIH87HL26H

Title of program project: SCOR in vascular research; PI - DE Strandness

Title of project: "Evaluation of the structure and composition of atherosclerotic plaques by magnetic resonance imaging (MRI)"; PI- Alan Nelson

T Richards - consultant

Period of support - January 1, 1990 - December 31, 1994

UW School of Medicine in house grant - Biomedical Research Support Grant

"NMR spectroscopy of Demyelination in the Primate Brain",

Period of support - January 1, 1986 - December 31, 1987

Publications:

My publications are now listed online at

https://www.researchgate.net/profile/Todd_Richards/contributions

See below for a complete list

My NIH Research Grant details are listed online at

https://projectreporter.nih.gov/reporter_searchresults.cfm

then type Richards, Todd at the PI query and submitted

A. Personal Statement

I am a Professor of Radiology at the University of Washington and a core member of the Integrated Brain Imaging Center (IBIC). I have 20 years experience researching children with learning disabilities. With Dr. Virginia Berninger we have over 30 publications as we have worked together at the University of Washington Learning Disability Center on three different 5 year cycles of P50-level NIH-funded research. I have 30 years’ experience with acquisition and data analysis of MR Imaging. On these studies, I provided the overall guidance on neuroimaging expertise including patient preparation, patient training, MR engineering/data acquisition/data analysis so that MR data can be quantitatively evaluated. My analysis software is used by several NIH-funded research projects here at the University of Washington. I am an expert on all aspects of MR imaging and can write software code for processing of both data analysis and acquisition. I have analyzed advanced MR imaging techniques such as proton MR spectroscopy and diffusion tensor imaging (DTI), and perfusion imaging as tools to study changes that occur in the brain in various disease conditions and disorders. I have worked on previous NIH-funded grants for over 30 years.

B. Positions and Honors

Research and professional experience:

1985-1990 Assistant Professor, Radiology, University of Washington, Seattle, WA

1991-1995 MRI consultant, Marion Merrell Dow Inc

1992-present Research Affiliate, Bloedel Hearing Research Center

1991-1998 Associate Professor, Radiology, University of Washington, Seattle, WA

1998-present Professor, Radiology, University of Washington, Seattle, WA

1995-present NIH reviewer and panel advisor for MR imaging

C. Contributions to Science

Contribution A. MR Imaging of Treatment in Learning Disabilities – As early as 2000, we have been among the first to understand the differences in language-related brain activation changes in the treatment of children with learning disabilities.

1. Richards TL, Corina D, Serafini S, Steury K, Echelard DR, Dager SR, Marro K, Abbott RD,

Maravilla KR, Berninger VW, The Effects of a Phonologically-Driven Treatment for

Dyslexia on Lactate Levels as Measured by Proton MR Spectroscopic Imaging,

AJNR, 21,916-922, 2000

2. Richards TL, Functional Magnetic Resonance Imaging and Spectroscopic Imaging of the Brain: Application

of fMRI and fMRS to Reading Disabilities and Education, Learning Disabilities Quarterly,

Special Issue, 24, 189 - 203, 2001.

3. Richards, T., Aylward, E., Berninger, V., Field, K., Parsons, A., Richards, A. and Nagy, W., Individual fMRI activation in orthographic mapping and morpheme mapping after orthographic or morphological spelling treatment in child dyslexics, Journal of Neurolinguistics, 19, 56-86, 2006

Interdisciplinary Research on Defining and Treating Specific Learning Disabilities I have served as project leader of the brain imaging subproject of NICHD P50 Multidisciplinary Center Grants on SLDs from 1995 to 2006 and 2011 to present . For reviews of this programmatic line of research on genetics, neuroscience, diagnostic assessment, and instructional intervention prior to 2011, see

Berninger, V., & Richards, T. (2010). Inter-relationships among behavioral markers, genes, brain, and treatment in dyslexia and dysgraphia. Future Neurology, 5, 597-617. doi: 10.2217/fnl.10.22)

Berninger, V., Raskind, W., Richards, T., Abbott, R., & Stock, P. (2008). A multidisciplinary approach to understanding developmental dyslexia within working-memory architecture: Genotypes, phenotypes, brain, and instruction. Developmental Neuropsychology, 33, 707-744.

More recently, the P50 Center has focused on defining and differentiating SLDs

based on brain and behavioral evidence and response to instruction. For representative recent

publications validating differentiation of dysgraphia (impaired handwriting), dyslexia (impaired word

reading and spelling), and oral and written language learning disability (OWL LD, aka SLI) on basis of brain, assessment and instruction, and genetic evidence), see

Richards TL, T Grabowksi, K Askren, P Boord, K Yagle, Z. Mestre, Robinson, O., Welker, D. Gulliford, V, Nagy, W Berninger (2015, posted on line March 28 ). Contrasting brain patterns of writing-related DTI parameters, fMRI connectivity, and DTI-fMRI connectivity correlations in children with and without dysgraphia or dyslexia Neuroimage Clinical. 24, 408-421

Results showed that controls displayed more white matter integrity but less fMRI connectivity than did those with dyslexia or dysgraphia, but those with dyslexia showed more fMRI over-connectivity than did those with dysgraphia compared to the controls. Coded transcription and translation variables in compositions written outside the scanner were correlated with the fMRI tasks for transcription (handwriting and spelling) and translation (idea flow during mind wandering in resting condition and planning for composing on provided topic). However, for children with dysgraphia and co-occurring ADHD (approximately half) none of the fMRI transcription or translation tasks were correlated with the coded transcription variables in compositions, consistent with an “invisible disability” in those whose attention problems interfere with their transcription. Following the computer lessons, changes in mean diffusivity and axial diffusivity were identified for children with dysgraphia. Graph analysis has been applied to study of the complex fMRI connectivity of the writing brain.

Patents - 2

Methods and systems for determining tumor boundary characteristics

Patent

Publication NumberUS 9370328StatusIssued PatentAvailabilityUnknownFiling Date2013-11-26Publication Date2016-06-21

Described herein are methods and systems for determining tumor boundary characteristics. One example method involves (a) receiving imaging data, wherein the imaging data indicates a tumor and one or more tissues that surround the tumor; (b) determining one or more radial segments that extend from the tumor to the one or more surrounding tissues based on the imaging data, wherein the one or more radial segments each comprise one or more respective data points indicating signal intensity; (c) d…

 Janet F Eary Todd L Richards

University of Washington

IMAGE NEUROGRAPHY AND DIFFUSION ANISOTROPY IMAGING

Patent

Publication NumberEP 630481 B1StatusIssued PatentAvailabilityUnknownFiling Date1993-03-08Publication Date1999-06-30

 Aaron G Filler Howe Franklyn A Cranmer Terrace Jay S Tsuruda Todd L Richards

University of Washington

Image neurography and diffusion anisotropy imaging

Patent

Publication NumberUS 5560360StatusIssued PatentAvailabilityUnknownFiling Date1993-03-08Publication Date1996-10-01

A neurography system (10) is disclosed for generating diagnostically useful images of neural tissue (i.e., neurograms) employing a modified magnetic resonance imaging system (14). In one embodiment, the neurography system selectively images neural tissue by employing one or more gradients to discriminate diffusion anisotropy in the tissue and further enhances the image by suppressing the contribution of fat to the image. The neurography system is part of a broader medical system (12), which m…

 Aaron G Filler Jay S Tsurda Todd L Richards Franklyn A Howe

University of Washington

Washington Research Foundation

Research Gate Statistics

Skills & Activities

Publication Highlights

Book Chapters

Stephen R. Dager, Neva M. Corrigan, Todd L. Richards, Dennis W. Shaw: Brain Chemistry: Magnetic Resonance Spectroscopy. Autism Spectrum Disorders, 05/2011: pages 576-592; , ISBN: 9780195371826, DOI:10.1093/med/9780195371826.003.0038

Todd L. Richards: Multinuclear Magnetic Resonance Spectroscopic Imaging. Encyclopedia of Analytical Chemistry, 09/2006; , ISBN: 9780470027318, DOI:10.1002/9780470027318.a0110

Todd L. Richards, Juan Acosta-Urquidi: Pulsing Magnetic Field Effects on Brain Electrical Activity in Multiple Sclerosis. Biologic Effects of Light 1998, 01/1999: pages 337-342; , DOI:10.1007/978-1-4615-5051-8_55

Ronald V. Dorn III, Merle L. Griebenow, Arlene L. Ackermann, Lowell G. Miller, Patrick R. Gavin, David L. Miller, Floyd J. Wheeler, Kenneth M. Bradshaw, Todd L. Richards, Daniel E. Wessol, Yale D. Harker, David W. Nigg, Peter D. Randolph, William F. Bauer: The Idaho Power Burst Facility/Boron Neutron Capture Therapy (PBF/BNCT) Program Overview. Progress in Neutron Capture Therapy for Cancer, 01/1992: pages 13-20; , DOI:10.1007/978-1-4615-3384-9_3

W. F. Bauer, K. M. Bradshaw, T. L. Richards: Interaction between Boron Containing Compounds and Serum Albumin Observed by Nuclear Magnetic Resonance. Progress in Neutron Capture Therapy for Cancer, 01/1992: pages 339-343; , ISBN: 978-1-4613-6494-8, DOI:10.1007/978-1-4615-3384-9_74

Kenneth M. Bradshaw, Todd L. Richards, Susan L. Kraft: In Vivo Pharmacokinetic Evaluation of Boron Compounds Using Magnetic Resonance Spectroscopy and Imaging. Progress in Neutron Capture Therapy for Cancer, 01/1992: pages 325-329; , ISBN: 978-1-4613-6494-8, DOI:10.1007/978-1-4615-3384-9_71

Journal Publications

Rebekah Petroff, Todd Richards, Brenda Crouthamel, Noelle McKain, Courtney Stanley,Kimberly S. Grant, Sara Shum, Jing Jing, Nina Isoherranen, Thomas M. Burbacher, Chronic, Low-Level Oral Exposure to Marine Toxin, Domoic Acid, Alters Whole Brain Morphometry in Nonhuman Primates, bioRxiv preprint first posted online Oct. 10, 2018; doi: http://dx.doi.org/10.1101/439109

Virginia W Berninger, Todd L Richards, Robert D Abbott: Brain and Behavioral Assessment of Executive Functions for Self-Regulating Levels of Language in Reading Brain. 11/2017; 3(11).

Ralph L. Elkins, Todd L. Richards, Robert Nielsen, Richard Repass, Henriettae Stahlbrandt, Hunter G. Hoffman: The Neurobiological Mechanism of Chemical Aversion (Emetic) Therapy for Alcohol Use Disorder: An fMRI Study. Frontiers in Behavioral Neuroscience 09/2017; 11:182., DOI:10.3389/fnbeh.2017.00182

Todd Richards, Mark Pettet, Mary Askren, Zoé Mestre, Thomas Grabowski, Kevin Yagle, Peter Wallis, Mary Northey, Robert Abbott, Virginia Berninger: ERPs While Judging Meaningfulness of Sentences With and Without Homonym or Morpheme Spelling Foils: Comparing 4th to 9th Graders With and Without Spelling Disabilities. Developmental Neuropsychology 06/2017; 42(4):1-14., DOI:10.1080/87565641.2016.1243110

Todd L Richards, Virginia W Berninger, Kevin J Yagle, Robert D Abbott, Daniel J Peterson: Changes in DTI Diffusivity and fMRI Connectivity Cluster Coefficients for Students with and without Specific Learning Disabilities In Written Language: Brains Response to Writing Instruction. 04/2017; 3(4):1-11.

Peter Wallis, Todd Richards, Peter Boord, Robert Abbott, Virginia Berninger: Relationships between Translation and Transcription Processes during fMRI Connectivity Scanning and Coded Translation and Transcription in Writing Products after Scanning in Children with and without Transcription Disabilities. Creative Education 04/2017; 8(05):716-748., DOI:10.4236/ce.2017.85055

Kathleen Nielsen, Kathryn Andria-Habermann, Todd Richards, Robert Abbott, Terry Mickail, Virginia Berninger: Emotional and Behavioral Correlates of Persisting Specific Learning Disabilities in Written Language During Middle Childhood and Early Adolescence. Journal of Psychoeducational Assessment 03/2017; 36(12):073428291769805., DOI:10.1177/0734282917698056

Todd L Richards, Robert D Abbott, Kevin Yagle, Dan Peterson, Wendy Raskind, Virginia W Berninger: Self-government of complex reading and writing brains informed by cingulo-opercular network for adaptive control and working memory components for language learning. 01/2017; 3(4):1-12., DOI:10.15761/JSIN.1000173

Kevin Yagle, Todd Richards, Katie Askren, Zoe Mestre, Scott Beers, Robert Abbott, William Nagy, Virginia Berninger: Relationships between Eye Movements during Sentence Reading Comprehension, Word Spelling and Reading, and DTI and fmri Connectivity In Students with and without Dysgraphia or Dyslexia. 01/2017; 3(1):1-11., DOI:10.15761/JSIN.1000150

Marieke Longcamp, Jean-luc Velay, Virginia Wise Berninger, Todd L. Richards: Neuroanatomy of Handwriting and Related Reading and Writing Skills in Adults and Children with and without Learning Disabilities: French-American Connections. 12/2016; 171-172(171-172)., DOI:10.4000/pratiques.3175

Patricia K. Kuhl, Jeff Stevenson, Neva M. Corrigan, Jasper J.F. van den Bosch, Dilara Deniz Can, Todd Richards: Neuroimaging of the bilingual brain: Structural brain correlates of listening and speaking in a second language. Brain and Language 11/2016; 162:1-9., DOI:10.1016/j.bandl.2016.07.004

Kristina M Adams Waldorf, Jennifer E Stencel-Baerenwald, Raj P Kapur, Colin Studholme, Erica Boldenow, Jay Vornhagen, Audrey Baldessari, Manjiri K Dighe, Jeff Thiel, Sean Merillat, Blair Armistead, Jennifer Tisoncik-Go, Richard R Green, Michael A Davis, Elyse C Dewey, Marian R Fairgrieve, J Christopher Gatenby, Todd Richards, Gwenn A Garden, Michael S Diamond, Sandra E Juul, Richard F Grant, LaRene Kuller, Dennis W W Shaw, Jason Ogle, G Michael Gough, Wonsok Lee, Chris English, Robert F Hevner, William B Dobyns, Michael Gale, Lakshmi Rajagopal: Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate. Nature Medicine 09/2016; 22(11)., DOI:10.1038/nm.4193

Todd Richards, Stephen Peverly, Amie Wolf, Robert Abbott, Steven Tanimoto, Rob Thompson, William Nagy, Virginia Berninger: Idea Units in Notes and Summaries for Read Texts by Keyboard and Pencil in Middle Childhood Students with Specific Learning Disabilities: Cognitive and Brain Findings. Trends in Neuroscience and Education 07/2016; 5(3)., DOI:10.1016/j.tine.2016.07.005

Ping C. Mamiya, Todd L. Richards, Bradley P. Coe, Evan E. Eichler, Patricia K. Kuhl: Brain white matter structure and COMT gene are linked to second-language learning in adults. Proceedings of the National Academy of Sciences 06/2016; 113(26):201606602., DOI:10.1073/pnas.1606602113

James S. Meabon, Bertrand R. Huber, Donna J. Cross, Todd L. Richards, Satoshi Minoshima, Kathleen F. Pagulayan, Ge Li, Kole D. Meeker, Brian C. Kraemer, Eric C. Petrie, Murray A. Raskind, Elaine R. Peskind, David G. Cook: Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Science translational medicine 01/2016; 8(321):321ra6-321ra6., DOI:10.1126/scitranslmed.aaa9585

Todd Richards, Robert D Abbott, Virginia W Berninger: Relationships between Presence or Absence of ADHD and fMRI Connectivity Writing Tasks in Children with Dysgraphia. 01/2016; 2(12).

Todd Richards, William Nagy, Robert Abbott, Virginia Berninger: Brain Connectivity Associated with Cascading Levels of Language. 01/2016; 2(4)., DOI:10.15761/JSIN.1000139

Natalia M Kleinhans, Todd Richards, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: Altered Dynamics of the fMRI Response to Faces in Individuals with Autism. Journal of Autism and Developmental Disorders 09/2015; 46(1)., DOI:10.1007/s10803-015-2565-8

Kurt E. Weaver, Todd L. Richards, Rebecca G. Logsdon, Ellen L. McGough, Satoshi Minoshima, Elizabeth H. Aylward, Natalia M. Kleinhans, Thomas J. Grabowski, Susan M. McCurry, Linda Teri: Posterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment. BioMed Research International 08/2015; 2015(3):1-13., DOI:10.1155/2015/610605

Elaine R. Peskind, Eric C. Petrie, Gail Li, Donna Cross, Vasily Yarnykh, Todd Richards, Satoshi Minoshima, Cynthia Mayer, Kathleen Pagulayan, Bertrand Russell Huber, James Meabon, Murray A. Raskind, Jing Zhang, David Cook: Neuroimaging and cerebrospinal fluid biomarkers in iraq and afghanistan veterans: Effects of deployment and blast concussion mild traumatic brain injury. Alzheimer's & dementia: the journal of the Alzheimer's Association 07/2015; 11(7):P513., DOI:10.1016/j.jalz.2015.06.615

Donna J Cross, Gregory G Garwin, Marcella M Cline, Todd L Richards, Vasily Yarnykh, Pierre D Mourad, Rodney J.Y. Ho, Satoshi Minoshima: Paclitaxel improves outcome from traumatic brain injury. Brain research 06/2015; 1618., DOI:10.1016/j.brainres.2015.06.006

Virginia W. Berninger, Todd L. Richards, Robert D. Abbott: Differential Diagnosis of Dysgraphia, Dyslexia, and OWL LD: Behavioral and Neuroimaging Evidence. Reading and Writing 04/2015; 28(8)., DOI:10.1007/s11145-015-9565-0

T.L. Richards, T.J. Grabowski, P. Boord, K. Yagle, M. Askren, Z. Mestre, P. Robinson, O. Welker, D. Gulliford, W. Nagy, V. Berninger: Contrasting brain patterns of writing-related DTI parameters, fMRI connectivity, and DTI-fMRI connectivity correlations in children with and without dysgraphia or dyslexia. NeuroImage: Clinical 03/2015; 342(C)., DOI:10.1016/j.nicl.2015.03.018

Mitsutomi Ischiyama, Todd Richards, Upendra Parvathaneni, Yoshimi Anzai: Dynamic contrast enhanced magnetic resonance imaging in Head and Neck Cancer- Differentiation of new H&N cancer, recurrent disease, and benign post-treatment changes. Clinical Imaging 02/2015; 39(4)., DOI:10.1016/j.clinimag.2015.01.016

Anna Marina, Anize Delfino van Frankenberg, Seda Suvag, Holly S Callahan, Mario Kratz, Todd L Richards, Kristina M Utzschneider: Effects of Dietary Fat and Saturated Fat Content on Liver Fat and Markers of Oxidative Stress in Overweight/Obese Men and Women under Weight-Stable Conditions. Nutrients 11/2014; 6(11):4678-90., DOI:10.3390/nu6114678

Li Ma, Joan S Roberts, Catherine Pihoker, Todd L Richards, Dennis W W Shaw, Ken I Marro, Monica S Vavilala: Transcranial Doppler-Based Assessment of Cerebral Autoregulation in Critically Ill Children During Diabetic Ketoacidosis Treatment. Pediatric Critical Care Medicine 07/2014; 15(8)., DOI:10.1097/PCC.0000000000000197

Elaine R. Peskind, Eric C. Petrie, Kathleen F. Pagulayan, Vasily Yarnykh, Donna J. Cross, Todd Richards, Murray A. Raskind, Jing Zhang, Thomas Montine, Satoshi Minoshima: PERSISTENT BRAIN NEUROIMAGING AND NEUROCOGNITIVE ABNORMALITIES IN MILITARY VETERANS WHO EXPERIENCED BLAST MILD TRAUMATIC BRAIN INJURY IN IRAQ AND AFGHANISTAN. Alzheimer's and Dementia 07/2014; 10(4):P294., DOI:10.1016/j.jalz.2014.04.487

Anand K Deo, Soo Borson, Jeanne M Link, Karen Domino, Janet F Eary, Ban Ke, Todd L Richards, David A Mankoff, Satoshi Minoshima, Finbarr O'Sullivan, Sara Eyal, Peng Hsiao, Ken Maravilla, Jashvant D Unadkat: Activity of P-Glycoprotein, a -Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease. Journal of Nuclear Medicine 05/2014; 55(7)., DOI:10.2967/jnumed.113.130161

Jeannie M Padowski, Kurt E Weaver, Todd L Richards, Mercy Y Laurino, Ali Samii, Elizabeth H Aylward, Kevin E Conley: Neurochemical Correlates of Caudate Atrophy in Huntington's Disease. Movement Disorders 03/2014; 29(3)., DOI:10.1002/mds.25801

T. L. Richards, M. Muzi, K. Marro, J. R. Fink, J. K. Rockhill, K. Krohn: Abstract B150: Are MRI/MRS methods complementary to FMISO-PET for evaluating hypoxia.. Molecular Cancer Therapeutics 01/2014; 12(11_Supplement):B150-B150., DOI:10.1158/1535-7163.TARG-13-B150

Christopher M Traudt, Ronald J McPherson, Larry A Bauer, Todd L Richards, Thomas M Burbacher, Ryan M McAdams, Sandra E Juul: Concurrent Erythropoietin and Hypothermia Treatment Improve Outcomes in a Term Nonhuman Primate Model of Perinatal Asphyxia. Developmental Neuroscience 11/2013; 35(6)., DOI:10.1159/000355460

Patricia K Kuhl, Todd L Richards, Jeff Stevenson, Dilara D Can, Liv Wroblewski, Melanie S Fish, Julia Mizrahi: White-matter microstructure differs in adult bilingual and monolingual brains. The Journal of the Acoustical Society of America 11/2013; 134(5):4249., DOI:10.1121/1.4831637

Leslie Dervan, Andrew Poliakov, Seth D Friedman, Dennis Shaw, Catherine Pihoker, Joan S Roberts, Todd Richards, Kenneth Marro, Monica S Vavilala: Change in fractional anisotropy during treatment of diabetic ketoacidosis in children. Pediatric Research 10/2013; 75(1-1)., DOI:10.1038/pr.2013.168

Eric C Petrie, Donna J Cross, Vasily L Yarnykh, Todd Richards, Nathalie M Martin, Kathleen Pagulayan, David Hoff, Kim Hart, Cynthia Mayer, Matthew Tarabochia, Murray A. Raskind, Satoshi Minoshima, Elaine R. Peskind: Neuroimaging, Behavioral, and Psychological Sequelae of Repetitive Combined Blast/Impact Mild Traumatic Brain Injury in Iraq and Afghanistan War Veterans. Journal of neurotrauma 10/2013; 31(5)., DOI:10.1089/neu.2013.2952

Lisa F Akiyama, Todd R Richards, Toshiaki Imada, Stephen R Dager, Liv Wroblewski, Patricia K Kuhl: Age-Specific Average Head Template for Typically Developing 6-Month-Old Infants. PLoS ONE 09/2013; 8(9):e73821., DOI:10.1371/journal.pone.0073821

Kurt E Weaver, Todd L Richards, Melissa Saenz, Helen Petropoulos, Ione Fine: Neurochemical Changes Within Human Early Blind Occipital Cortex. Neuroscience 08/2013; 252., DOI:10.1016/j.neuroscience.2013.08.004

Neva M Corrigan, Dennis W W Shaw, Annette M Estes, Todd L Richards, Jeff Munson, Seth D Friedman, Geraldine Dawson, Alan A Artru, Stephen R Dager: Atypical Developmental Patterns of Brain Chemistry in Children With Autism Spectrum Disorder. JAMA Psychiatry 07/2013; 70(9)., DOI:10.1001/jamapsychiatry.2013.1388

Matakazu Furukawa, Upendra Parvathaneni, Kenneth Maravilla, Todd L Richards, Yoshimi Anzai: Dynamic contrast-enhanced MR perfusion imaging of head and neck tumors at 3 Tesla. Head & Neck 07/2013; 35(7)., DOI:10.1002/hed.23051

Donna J Cross, Yoshimi Anzai, Eric C Petrie, Nathalie Martin, Todd L Richards, Kenneth R Maravilla, Elaine R Peskind, Satoshi Minoshima: Loss of Olfactory Tract Integrity Affects Cortical Metabolism in the Brain and Olfactory Regions in Aging and Mild Cognitive Impairment. Journal of Nuclear Medicine 06/2013; 54(8)., DOI:10.2967/jnumed.112.116558

Frederick Reitz, Todd Richards, Kelvin Wu, Peter Boord, Mary Askren, Thomas Lewis, Virginia Berninger: A Low-Cost, Computer-Interfaced Drawing Pad for fMRI Studies of Dysgraphia and Dyslexia. Sensors 04/2013; 13(4):5099-108., DOI:10.3390/s130405099

J. Padowski, K. Weaver, T. Richards, M. Laurino, A. Samii, E. Aylward, K. Conley: Altered caudate glutamate-glutamine in Huntington disease. Neurotherapeutics 01/2013; 10(1):181-181.

Dilara Deniz Can, Todd Richards, Patricia K Kuhl: Early gray-matter and white-matter concentration in infancy predict later language skills: A whole brain voxel-based morphometry study. Brain and Language 12/2012; 124(1):34-44., DOI:10.1016/j.bandl.2012.10.007

Achim Gass, Todd L Richards: Serial proton magnetic resonance spectroscopy of normal-appearing gray and white matter in MS. Neurology 11/2012; 80(1)., DOI:10.1212/WNL.0b013e31827b1b4c

K.A. Krohn, M. Muzi, J.M. Link, T.L. Richards, J.R. Fink, J.K. Rockhill, J.F. Eary: 455 Role of Hypoxia Imaging with [F-18]FMISO-PET and BOLD-MRI in Clinical Trials. European Journal of Cancer 11/2012; 48(6):141., DOI:10.1016/S0959-8049(12)72253-0

Andrew P Prescot, Todd Richards, Stephen R Dager, Changho Choi, Perry F Renshaw: Phase-adjusted echo time (PATE)-averaging 1H MRS: Application for improved glutamine quantification at 2.89T. NMR in Biomedicine 11/2012; 25(11):1245-52., DOI:10.1002/nbm.2795

Elaine R. Peskind, Donna J. Cross, Vasily Yarnykh, Kathleen Pagulayan, David Hoff, Kim Hart, Nathalie Martin, Todd Richards, Murray A. Raskind, Satoshi Minoshima, Eric C. Petrie: Neuroimaging biomarkers in veterans with blast-mild traumatic brain injury with or without comorbid PTSD. 09/2012; 3., DOI:10.3402/ejpt.v3i0.19376

Natalia M Kleinhans, Gregory Pauley, Todd Richards, Emily Neuhaus, Nathalie Martin, Neva M Corrigan, Dennis W Shaw, Annette Estes, Stephen R Dager: Age-related abnormalities in white matter microstructure in autism spectrum disorders. Brain research 08/2012; 1479:1-16., DOI:10.1016/j.brainres.2012.07.056

Kristina M Utzschneider, Jennifer L Bayer-Carter, Matthew D Arbuckle, Jaime M Tidwell, Todd L Richards, Suzanne Craft: Beneficial effect of a weight-stable, low-fat/low-saturated fat/low-glycaemic index diet to reduce liver fat in older subjects. The British journal of nutrition 07/2012; 109(06):1-9., DOI:10.1017/S0007114512002966

Anand Deo, Soo Borson, Jeanne Link, Janet Eary, Todd Richards, David Mankoff, Peng Hsiao, Satoshi Minoshima, Ken Maravilla, Jashvant Unadkat: Activity of P-glycoprotein, an ABC efflux transporter at the blood-brain barrier, is compromised in Alzheimer's disease. Alzheimer's and Dementia 07/2012; 8(4):P698., DOI:10.1016/j.jalz.2012.05.1880

Wendy Herlihy Raskind, Beate Peter, Todd L Richards, Mark M Eckert, Virginia Wise Berninger: The Genetics of Reading Disabilities: From Phenotypes to Candidate Genes. Frontiers in Psychology 01/2012; 3:601., DOI:10.3389/fpsyg.2012.00601

F. O'Sullivan, E. Wolsztynski, J. O'Sullivan, T. Richards, E.U. Conrad, J.F. Eary: A Statistical Modeling Approach to the Analysis of Spatial Patterns of FDG-PET Uptake in Human Sarcoma. IEEE Transactions on Medical Imaging 01/2012; 30(12-30):2059 - 2071., DOI:10.1109/TMI.2011.2160984

Neva M Corrigan, Todd L Richards, Darold A Treffert, Stephen R Dager: Toward a better understanding of the savant brain. Comprehensive psychiatry 12/2011; 53(6):706-17., DOI:10.1016/j.comppsych.2011.11.006

Todd L Richards, Janet F Eary, Finbarr O'sullivan, Ernest U Conrad: A method for characterizing sarcoma tumour boundary scanned with T2-weighted MRI.

Elizabeth N. Jacobson Misbe, Todd L Richards, Ronald J McPherson, Thomas M Burbacher, Sandra E Juul: Perinatal Asphyxia in a Nonhuman Primate Model. Developmental Neuroscience 06/2011; 33(3-4):210-21., DOI:10.1159/000327246

Todd L. Richards, Virginia W. Berninger, Pat Stock, Leah Altemeier, Pamala Trivedi, Kenneth R. Maravilla: Differences between good and poor child writers on fMRI contrasts for writing newly taught and highly practiced letter forms. Reading and Writing 05/2011; 24(5):493-516., DOI:10.1007/s11145-009-9217-3

Monica S Vavilala, Ken I Marro, Todd L Richards, Joan S Roberts, Parichat Curry, Catherine Pihoker, Heidi Bradford, Dennis Shaw: Change in Mean Transit Time, Apparent Diffusion Coefficient and Cerebral Blood Volume during Pediatric Diabetic Ketoacidosis Treatment. Pediatric Critical Care Medicine 04/2011; 12(6):e344-9., DOI:10.1097/PCC.0b013e3182196c9c

Hunter G Hoffman, Gloria T Chambers, Walter J Meyer, Lisa L Arceneaux, William J Russell, Eric J Seibel, Todd L Richards, Sam R Sharar, David R Patterson: Virtual Reality as an Adjunctive Non-pharmacologic Analgesic for Acute Burn Pain During Medical Procedures. Annals of Behavioral Medicine 04/2011; 41(2):183-91., DOI:10.1007/s12160-010-9248-7

Kristina H Deeter, Joan S Roberts, Heidi Bradford, Todd Richards, Dennis Shaw, Kenneth Marro, Harvey Chiu, Catherine Pihoker, Anne Lynn, Monica S Vavilala: Hypertension Despite Dehydration During Severe Pediatric Diabetic Ketoacidosis. Pediatric Diabetes 03/2011; 12(4 Pt 1):295-301., DOI:10.1111/j.1399-5448.2010.00695.x

Neva M Corrigan, Dennis W W Shaw, Todd L Richards, Annette M Estes, Seth D Friedman, Helen Petropoulos, Alan A Artru, Stephen R Dager: Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders 03/2011; 42(1):105-15., DOI:10.1007/s10803-011-1216-y

Finbarr O'Sullivan, Eric Wolsztynski, Janel N. O'Sullivan, T. Richards, E. U. Conrad, J. F. Eary: A Statistical Modeling Approach to the Analysis of Spatial Patterns of FDG-PET Uptake in Human Sarcoma..

Natalia M Kleinhans, Todd Richards, L Clark Johnson, Kurt E Weaver, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: FMRI evidence of neural abnormalities in the subcortical face processing system in ASD. NeuroImage 01/2011; 54(1):697-704., DOI:10.1016/j.neuroimage.2010.07.037

K. A. Krohn, T.L. Richards: 616 Imaging heterogeneity of hypoxia: spatial and temporal. EJC Supplements 11/2010; 8(7):193-193., DOI:10.1016/S1359-6349(10)72323-5

Natalia M Kleinhans, Todd Richards, Kurt Weaver, L Clark Johnson, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: Association between amygdala response to emotional faces and social anxiety in autism spectrum disorders. Neuropsychologia 10/2010; 48(12):3665-70., DOI:10.1016/j.neuropsychologia.2010.07.022

Kurt E. Weaver, Rebecca G. Logsdon, Todd L. Richards, Ellen L. McGough, Susan M. McCurry, Linda Teri: Elevated Lactate within the Posterior Cingulate is Associated with Poorer Memory Function in MCI: A 2D J-Resolved Spectroscopic MRI Study. Alzheimer's and Dementia 07/2010; 6(4)., DOI:10.1016/j.jalz.2010.05.156

Rebecca G. Logsdon, Ellen L. McGough, Kurt E. Weaver, Todd L. Richards, Susan M. McCurry, Linda Teri: Physical Function and Magnetic Resonance Spectroscopy of the Medial Temporal Lobe in Older Adults with MCI. Alzheimer's and Dementia 07/2010; 6(4)., DOI:10.1016/j.jalz.2010.05.119

Virginia Berninger, Todd Richards: Inter-relationships among behavioral markers, genes, brain and treatment in dyslexia and dysgraphia. Future Neurology 07/2010; 5(4):597-617., DOI:10.2217/fnl.10.22

Steven M Demorest, Steven J Morrison, Laura A Stambaugh, Münir Beken, Todd L Richards, Clark Johnson: An fMRI investigation of the cultural specificity of music memory. Social Cognitive and Affective Neuroscience 06/2010; 5(2-3):282-91., DOI:10.1093/scan/nsp048

Sara J Webb, Emily J.H. Jones, Kristen Merkle, Michael Murias, Jessica Greenson, Todd Richards, Elizabeth Aylward, Geraldine Dawson: Response to familiar faces, newly familiar faces, and novel faces as assessed by ERPs is intact in adults with autism spectrum disorders. International journal of psychophysiology: official journal of the International Organization of Psychophysiology 05/2010; 77(2):106-17., DOI:10.1016/j.ijpsycho.2010.04.011

Neva M Corrigan, Todd L Richards, Seth D Friedman, Helen Petropoulos, Stephen R Dager: Improving 1H MRSI measurement of cerebral lactate for clinical applications. Psychiatry Research 03/2010; 182(1):40-7., DOI:10.1016/j.pscychresns.2009.11.007

Ryan Michael McAdams, Todd L. Richards: Detection of nonketotic hyperglycinemia in a neonate using proton magnetic resonance spectroscopy. Radiology Case Reports 10/2009; 4(4)., DOI:10.2484/rcr.v4i4.310

Monica S Vavilala, Todd L Richards, Joan S Roberts, Harvey Chiu, Catherine Pihoker, Heidi Bradford, Kristina Deeter, Ken I Marro, Dennis Shaw: Change in blood-brain barrier permeability during pediatric diabetic ketoacidosis treatment. Pediatric Critical Care Medicine 10/2009; 11(3):332-8., DOI:10.1097/PCC.0b013e3181c013f4

Neva M. Corrigan, Todd Richards, Sara Jane Webb, Michael Murias, Kristen Merkle, Natalia M. Kleinhans, L. Clark Johnson, Andrew Poliakov, Elizabeth Aylward, Geraldine Dawson: An Investigation of the Relationship Between fMRI and ERP Source Localized Measurements of Brain Activity during Face Processing. Brain Topography 09/2009; 22(2):83-96., DOI:10.1007/s10548-009-0086-5

Susan J Astley, Elizabeth H Aylward, Heather Carmichael Olson, Kimberly Kerns, Allison Brooks, Truman E Coggins, Julian Davies, Susan Dorn, Beth Gendler, Tracy Jirikowic, Paul Kraegel, Kenneth Maravilla, Todd Richards: Magnetic Resonance Imaging Outcomes From a Comprehensive Magnetic Resonance Study of Children With Fetal Alcohol Spectrum Disorders. Alcoholism Clinical and Experimental Research 08/2009; 33(10):1671-89., DOI:10.1111/j.1530-0277.2009.01004.x

LC Johnson, TL Richards: A Tool to Support the Design of an Appropriate Bandpass Filter for fMRI Analysis. NeuroImage 07/2009; 47., DOI:10.1016/S1053-8119(09)70258-7

TL Richards, LC Johnson, J Stevenson: A Technique for Assessing the Influence of Respiration on the Real-Component of the Complex Reconstruction of fMRI data. NeuroImage 07/2009; 47., DOI:10.1016/S1053-8119(09)72061-0

Todd L. Richards, Virginia W. Berninger, Michel Fayol: fMRI activation differences between 11-year-old good and poor spellers' access in working memory to temporary and long-term orthographic representations. Journal of Neurolinguistics 07/2009; 22(4-22):327-353., DOI:10.1016/j.jneuroling.2008.11.002

Sara Jane Webb, Kristen Merkle, Michael Murias, Todd Richards, Elizabeth Aylward, Geraldine Dawson: ERP responses differentiate inverted but not upright face processing in adults with ASD. Social Cognitive and Affective Neuroscience 06/2009; 7(5):578-87., DOI:10.1093/scan/nsp002

NM Kleinhans, LC Johnson, T Richards, J Greenson, G Dawson, EH Aylward: Abnormal Functional Connectivity during Emotional Face Processing is Associated with Neural Abnormalities in the Amygdala in Autism Spectrum Disorders. NeuroImage 05/2009; 47., DOI:10.1016/S1053-8119(09)70059-X

James E. Nelson, Bryan D. Maliken, Cheryl Saunders, Jeff Stevenson, Todd Richards, Kris V. Kowdley: T1019 A Randomized, Masked, Controlled Study of Omega3 Polyunsaturated Fatty Acid vs Monounsaturated Fatty Acid Diet Supplementation for the Treatment of Nonalcoholic Fatty Liver Disease. Gastroenterology 05/2009; 136(5)., DOI:10.1016/S0016-5085(09)63906-8

Virginia W. Berninger, Todd L. Richards, Patricia S. Stock, Robert D. Abbott, Pamala A. Trivedi, Leah E. Altemeier, John R. Hayes: fMRI activation related to nature of ideas generated and differences between good and poor writers during idea generation. British Journal of Educational Psychology 05/2009; 1(1):77-93., DOI:10.1348/978185409X421949

Todd L Richards, Virginia W Berninger, Pat Stock, Leah Altemeier, Pamala Trivedi, Ken Maravilla: fMRI Sequential-Finger Movement Activation Differentiating Good and Poor Writers. Journal of Clinical and Experimental Neuropsychology 05/2009; 31(8):967-83., DOI:10.1080/13803390902780201

Kurt E Weaver, Todd L Richards, Olivia Liang, Mercy Y Laurino, Ali Samii, Elizabeth H Aylward: Longitudinal diffusion tensor imaging in Huntington's Disease. Experimental Neurology 05/2009; 216(2):525-9., DOI:10.1016/j.expneurol.2008.12.026

Susan J Astley, Todd Richards, Elizabeth H Aylward, Heather Carmichael Olson, Kimberly Kerns, Allison Brooks, Truman E Coggins, Julian Davies, Susan Dorn, Beth Gendler, Tracy Jirikowic, Paul Kraegel, Kenneth Maravilla: Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol syndrome. Magnetic Resonance Imaging 04/2009; 27(6):760-78., DOI:10.1016/j.mri.2009.01.003

Todd Richards, Virginia Berninger, William Winn, H. Lee Swanson, Olivia Lianga Patricia Stock: Differences between Children with and Without Spelling Disability. Journal of Writing Research 03/2009; 1(2):93-123., DOI:10.17239/jowr-2009.01.02.1

Susan J Astley, Elizabeth H Aylward, Heather Carmichael Olson, Kimberly Kerns, Allison Brooks, Truman E Coggins, Julian Davies, Susan Dorn, Beth Gendler, Tracy Jirikowic, Paul Kraegel, Kenneth Maravilla, Todd Richards: Functional magnetic resonance imaging outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. Journal of Neurodevelopmental Disorders 03/2009; 1(1):61-80., DOI:10.1007/s11689-009-9004-0

Natalia M Kleinhans, Todd Richards, Kurt E Weaver, Olivia Liang, Geraldine Dawson, Elizabeth Aylward: Brief Report: Biochemical Correlates of Clinical Impairment in High Functioning Autism and Asperger's Disorder. Journal of Autism and Developmental Disorders 03/2009; 39(7):1079-86., DOI:10.1007/s10803-009-0707-6

Natalia M Kleinhans, L Clark Johnson, Todd Richards, Roderick Mahurin, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: Reduced Neural Habituation in the Amygdala and Social Impairments in Autism Spectrum Disorders. American Journal of Psychiatry 03/2009; 166(4):467-75., DOI:10.1176/appi.ajp.2008.07101681

Susan J Astley, Heather Carmichael Olson, Kimberly Kerns, Allison Brooks, Elizabeth H Aylward, Truman E Coggins, Julian Davies, Susan Dorn, Beth Gendler, Tracy Jirikowic, Paul Kraegel, Kenneth Maravilla, Todd Richards: Neuropsyschological and behavioral outcomes from a comprehensive magnetic resonance study of children with Fetal Alcohol Spectrum Disorders. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 02/2009; 16(1):e178-201.

K.E. Weaver, T.L. Richards, O. Liang, E.H. Aylward: Poster 9: Corticostriatal Abnormalities in HD: A Combined Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging Study. Neurotherapeutics 01/2009; 6(1):206–207., DOI:10.1016/j.nurt.2008.10.010

Virginia W. Berninger, Todd Richards, Robert Abbott: The Role of the Hand in Written Idea Expression 12.

Charles Sabine, K. Trembath, A. Churchyard, Z. Horton, L. Tippett, V. Hogg, R. Roxburgh, D. Velakoulis, V. Collins, M. Delatycki, E. Aylward, P. Nopoulos, H. Johnson, A. Juhl, V. Magnotta, R. Pierson, D. Langbehn, C. Ross, J. Paulsen, PREDICT-HD Investigators of the Huntington Study Group, Lewis Maltby, K. L. Poston, C. Tang, A. Feigin, Y. Ma, M. Guttman, J. S. Paulsen, V. Dhawan, D. Eidelberg, The Huntington Study Group, Russell Katz, L. Veatch Goodman, J. Giuliano, D. Lovecky, K. Quaid, L. Dure, A. Goh, O. Yastrubetskaya, E. Chiu, K. Evans, K. Anderson, B. Borowsky, K. Duff, A. Ho, T. Sills, A. Vaccarino, D. Van Kammen, FuRST-pHD and PREDICT-HD Investigators and Coordinators of the Huntington Study Group, R. C. Block, E. R. Dorsey, C. A. Beck, I. Shoulson, Huntington Study Group TREND-HD Investigators, E. Pirogovsky, B. Bartlett, A. Callazo, J. Goldstein, G. Peavy, M. Jacobson, J. Corey-Bloom, P. Gilbert, S. Lessig, G. M. Peavy, K. E. Weaver, T. L. Richards, O. Liang, E. H. Aylward, L. J. Beglinger, W. H. Adams, H. Paulson, J. G. Fiedorowicz, D. R. Langbehn, A. Leserman, K. E. Conley, S. Jubrias, C. Amara, E. Shankland, D. J. Marcinek, J. F. O’Rourke, C. Wang, J. C. Stout, K. Rowe, A. D. Kloos, D. A. Kegelmeyer, S. K. Kostyk, P. Chua, P. Desmond, S. Christensen, C. Steward, F. Judd, J. Lloyd, B. Tress, M. Pugliese, P. Phan, J. Sanchez-Ramos, E. Oster, J. Bausch, A. Shinaman, E. Kayson, D. Oakes, Huntington Study Group PHAROS Investigators, Huntington Study Group COHORT Investigators, L. Oelke, L. Butterfield, C. Cimino, M. McCall, L. Ling, B. Stell, J. Annis, J. Cha, P. Como: Second Annual Huntington Disease Clinical Research Symposium. Neurotherapeutics 01/2009; 6(1):202-212., DOI:10.1016/j.nurt.2008.09.004

Todd Richards, Virginia Berninger, William Winn, H. Lee Swanson, Patricia Stock, Olivia Liang & Robert Abbott: Differences in fMRI activation between children with and without spelling disability on 2-back/0-back working memory contrast. Journal of Writing Research 01/2009; 1.

Todd L Richards, Virginia W Berninger: Abnormal fMRI Connectivity in Children with Dyslexia During a Phoneme Task: Before But Not After Treatment. Journal of Neurolinguistics 08/2008; 21(4):294-304., DOI:10.1016/j.jneuroling.2007.07.002

T Richards, J Stevenson, J Crouch, L.C. Johnson, K Maravilla, P. R. A. Stock, R Abbott, V Berninger: Tract-Based Spatial Statistics of Diffusion Tensor Imaging in Adults with Dyslexia. American Journal of Neuroradiology 07/2008; 29(6):1134-9., DOI:10.3174/ajnr.A1007

Stephen R Dager, Neva M Corrigan, Todd L Richards, Stefan Posse: Research Applications of Magnetic Resonance Spectroscopy (MRS) to Investigate Psychiatric Disorders. Topics in magnetic resonance imaging: TMRI 05/2008; 19(2):81-96., DOI:10.1097/RMR.0b013e318181e0be

Natalia M Kleinhans, Todd Richards, Lindsey Sterling, Keith C Stegbauer, Roderick Mahurin, L Clark Johnson, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: Abnormal functional connectivity in Autism Spectrum Disorders during face processing. Brain 05/2008; 131(Pt 4):1000-12., DOI:10.1093/brain/awm334

Rajeev D S Raizada, Todd L Richards, Andrew Meltzoff, Patricia K Kuhl: Socioeconomic status predicts hemispheric specialisation of the left inferior frontal gyrus in young children. NeuroImage 05/2008; 40(3):1392-401., DOI:10.1016/j.neuroimage.2008.01.021

S. R. Dager, S. Friedman, N. Oskin, T. Richards, D. L. Dunner, I. K. Lyoo, P. Renshaw: Shared brain changes in bipolar and panic disorder. Journal of Affective Disorders 03/2008; 107(1)., DOI:10.1016/j.jad.2007.12.221

Virginia W Berninger, Wendy Raskind, Todd Richards, Robert Abbott, Pat Stock: A Multidisciplinary Approach to Understanding Developmental Dyslexia Within Working-Memory Architecture: Genotypes, Phenotypes, Brain, and Instruction. Developmental Neuropsychology 02/2008; 33(6):707-44., DOI:10.1080/87565640802418662

Soo Borson, James Scanlan, Seth Friedman, Elizabeth Zuhr, Julie Fields, Elizabeth Aylward, Rodney Mahurin, Todd Richards, Yoshimi Anzai, Michi Yukawa, Shingshing Yeh: Modeling the impact of COPD on the brain. International Journal of COPD 02/2008; 3(3):429-34.

Hunter G Hoffman, Todd L Richards, Trevor Van Oostrom, Barbara A Coda, Mark P Jensen, David K Blough, Sam R Sharar: The Analgesic Effects of Opioids and Immersive Virtual Reality Distraction: Evidence from Subjective and Functional Brain Imaging Assessments. Anesthesia and analgesia 01/2008; 105(6):1776-83, table of contents., DOI:10.1213/01.ane.0000270205.45146.db

Todd Richards, Virginia Berninger, William Winn, Pat Stock, Richard Wagner, Andrea Muse, Kenneth Maravilla: Functional MRI Activation in Children With and Without Dyslexia During Pseudoword Aural Repeat and Visual Decode: Before and After Treatment. Neuropsychology 12/2007; 21(6):732-41., DOI:10.1037/0894-4105.21.6.732

Natalia M Kleinhans, Leonard C Johnson, Roderick Mahurin, Todd Richards, Keith C Stegbauer, Jessica Greenson, Geraldine Dawson, Elizabeth Aylward: Increased amygdala activation to neutral faces is associated with better face memory performance. Neuroreport 08/2007; 18(10):987-91., DOI:10.1097/WNR.0b013e328165d189

Azucena Garcia-Palacios, Hunter G Hoffman, Todd R Richards, Eric J Seibel, Sam R Sharar: Use of Virtual Reality Distraction to Reduce Claustrophobia Symptoms during a Mock Magnetic Resonance Imaging Brain Scan: A Case Report. CyberPsychology & Behavior 07/2007; 10(3):485-8., DOI:10.1089/cpb.2006.9926

Sandra E Juul, Elizabeth Aylward, Todd Richards, Ronald J McPherson, John Kuratani, Thomas M Burbacher: Prenatal Cord Clamping in Newborn Macaca nemestrina: A Model of Perinatal Asphyxia. Developmental Neuroscience 02/2007; 29(4-5):311-20., DOI:10.1159/000105472

Robert H Paul, Constantin T Yiannoutsos, Eric N Miller, Linda Chang, Christina M Marra, Giovanni Schifitto, Thomas Ernst, Elyse Singer, Todd Richards, G Jeffrey Jarvik, Richard Price, Dieter J Meyerhoff, Dennis Kolson, Ronald J Ellis, Gilberto Gonzalez, Robert E Lenkinski, Ronald A Cohen, Bradford A Navia: Proton MRS and Neuropsychological Correlates in AIDS Dementia Complex: Evidence of Subcortical Specificity. Journal of Neuropsychiatry 02/2007; 19(3):283-92., DOI:10.1176/appi.neuropsych.19.3.283

Azucena Garcia-Palacios, Hunter Hoffman, Todd Richards, Sam Sharar: Use of virtual reality to reduce claustrophobia during MRI scans. CyberPsychology & Behavior 12/2006; 9(6):707-708.

William Winn, Virginia Berninger, Todd Richards, Elizabeth Aylward, Pat Stock, Yen-Ling Lee, Dan Lovitt: Effects of Nonverbal Problem Solving Treatment on Skills for Externalizing Visual Representation in Upper Elementary Grade Students with and without Dyslexia. Journal of Educational Computing Research 11/2006; 34(4):381-404., DOI:10.2190/R783-4G36-58V7-5154

Hunter G Hoffman, Eric J Seibel, Todd L Richards, Thomas A Furness, David R Patterson, Sam R Sharar: Virtual Reality Helmet Display Quality Influences the Magnitude of Virtual Reality Analgesia. Journal of Pain 11/2006; 7(11):843-50., DOI:10.1016/j.jpain.2006.04.006

L Clark Johnson, Todd L Richards, Kristen H Archbold, Carol A Landis: Functional Magnetic Resonance Imaging in Nursing Research. Biological Research for Nursing 08/2006; 8(1):43-54., DOI:10.1177/1099800406289341

Larissa I Stanberry, Todd L Richards, Virginia W Berninger, Rajesh R Nandy, Elizabeth H Aylward, Kenneth R Maravilla, Patricia S Stock, Dietmar Cordes: Low-frequency signal changes reflect differences in functional connectivity between good readers and dyslexics during continuous phoneme mapping. Magnetic Resonance Imaging 05/2006; 24(3):217-29., DOI:10.1016/j.mri.2005.12.006

Hunter G Hoffman, Todd L Richards, Aric R Bills, Trevor Van Oostrom, Jeff Magula, Eric J Seibel, Sam R Sharar: Using fMRI to Study the Neural Correlates of Virtual Reality Analgesia. CNS spectrums 02/2006; 11(1):45-51., DOI:10.1017/S1092852900024202

Todd L Richards, Elizabeth H Aylward, Katherine M Field, Amie C Grimme, Wendy Raskind, Anne L Richards, William Nagy, Mark Eckert, Christiana Leonard, Robert D Abbott, Virginia W Berninger: Converging Evidence for Triple Word Form Theory in Children With Dyslexia. Developmental Neuropsychology 02/2006; 30(1):547-89., DOI:10.1207/s15326942dn3001_3

Todd L. Richards, Elizabeth H. Aylward, Virginia W. Berninger, Katherine M. Field, Amie C. Grimme, Anne L. Richards, William Nagy: Individual fMRI activation in orthographic mapping and morpheme mapping after orthographic or morphological spelling treatment in child dyslexics. Journal of Neurolinguistics 01/2006; 19(1-19):56-86., DOI:10.1016/j.jneuroling.2005.07.003

Jeanne Achterberg, Karin Cooke, Todd Richards, Leanna J Standish, Leila Kozak, James Lake: Evidence for Correlations Between Distant Intentionality and Brain Function in Recipients: A Functional Magnetic Resonance Imaging Analysis. The Journal of Alternative and Complementary Medicine 01/2006; 11(6):965-71., DOI:10.1089/acm.2005.11.965

Todd L Richards, Leila Kozak, L Clark Johnson, Leanna J Standish: Replicable Functional Magnetic Resonance Imaging Evidence of Correlated Brain Signals Between Physically and Sensory Isolated Subjects. The Journal of Alternative and Complementary Medicine 12/2005; 11(6):955-63., DOI:10.1089/acm.2005.11.955

Mark A Eckert, Christiana M Leonard, Marko Wilke, Mathew Eckert, Todd Richards, Anne Richards, Virginia Berninger: Anatomical Signatures of Dyslexia in Children: Unique Information from Manual and Voxel Based Morphometry Brain Measures. Cortex 07/2005; 41(3):304-15., DOI:10.1016/S0010-9452(08)70268-5

Jennifer B. Thomson, Belle Chenault, Robert D. Abbott, Wendy H. Raskind, Todd Richards, Elizabeth Aylward, Virginia W. Berninger: Converging evidence for attentional influences on the orthographic word form in child dyslexics. Journal of Neurolinguistics 03/2005; 18(2):93-126., DOI:10.1016/j.jneuroling.2004.11.005

E H Aylward, J E Park, K M Field, AC Parsons, T L Richards, S C Cramer, Andrew N. Meltzoff: Brain Activation during Face Perception: Evidence of a Developmental Change. Journal of Cognitive Neuroscience 03/2005; 17(2):308-19., DOI:10.1162/0898929053124884

Todd Richards, Virginia Berninger, William Nagy, Aimee Parsons, Katherine Field, Anne Richards: Brain activation during language task contrasts in children with and without dyslexia: Inferring mapping processes and assessing response to spelling instruction. Educational and Child Psychology 01/2005; 22(2):62-80.

L Chang, P L Lee, C T Yiannoutsos, T Ernst, C M Marra, T Richards, D Kolson, G Schifitto, J G Jarvik, E N Miller, R Lenkinski, G Gonzalez, B.A. Navia: A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. NeuroImage 01/2005; 23(4):1336-47., DOI:10.1016/j.neuroimage.2004.07.067

Constantin T Yiannoutsos, Thomas Ernst, Linda Chang, P Lani Lee, Todd Richards, Christina M Marra, Dieter J Meyerhoff, Jeffrey G Jarvik, Dennis Kolson, Giovanni Schifitto, Ronald J Ellis, Susan Swindells, David M Simpson, Eric N Miller, R Gilberto Gonzalez, Bradford A Navia: Regional patterns of brain metabolites in AIDS dementia complex. NeuroImage 12/2004; 23(3):928-35., DOI:10.1016/j.neuroimage.2004.07.033

Hunter G Hoffman, Sam R Sharar, Barbara Coda, John J Everett, Marcia Ciol, Todd Richards, David R Patterson: Manipulating presence influences the magnitude of virtual reality analgesia. Pain 09/2004; 111(1-2):162-8., DOI:10.1016/j.pain.2004.06.013

Hunter G Hoffman, Todd L Richards, Barbara Coda, Aric R Bills, David Blough, Anne L Richards, Sam R Sharar: Modulation of thermal pain-related brain activity with virtual reality: Evidence from fMRI. Neuroreport 06/2004; 15(8):1245-8., DOI:10.1097/01.wnr.0000127826.73576.91

Leanna J Standish, Leila Kozak, L Clark Johnson, Todd Richards: Electroencephalographic Evidence of Correlated Event-Related Signals Between the Brains of Spatially and Sensory Isolated Human Subjects. The Journal of Alternative and Complementary Medicine 04/2004; 10(2):307-14., DOI:10.1089/107555304323062293

C Ramon, J Haueisen, T Richards, K Maravilla: Multimodal Imaging of Somatosensory Evoked Cortical Activity. Neurology & Clinical Neurophysiology 02/2004; 2004(s2):96., DOI:10.1515/bmte.2001.46.s2.237

Hunter G Hoffman, Todd L Richards, Jeff Magula, Eric J Seibel, Cecil Hayes, Mark Mathis, Sam R Sharar, Kenneth Maravilla: A Magnet-Friendly Virtual Reality Fiberoptic Image Delivery System. CyberPsychology & Behavior 01/2004; 6(6):645-8., DOI:10.1089/109493103322725423

E.H. Aylward, T.L. Richards, V.W. Berninger, W.E. Nagy, K.M. Field, A.C. Grimme, A.L. Richards, J B Thomson, S.C. Cramer: Instructional treatment associated with changes in brain activation in children with dyslexia. Neurology 08/2003; 61(2):212-9., DOI:10.1212/01.WNL.0000068363.05974.64

Patricia Lani Lee, Constantin T Yiannoutsos, Thomas Ernst, Linda Chang, Christina M Marra, Jeffrey G Jarvik, Todd L Richards, Edmund W Kwok, Dennis L Kolson, David Simpson, Cheuk Y Tang, Giovanni Schifitto, Leena M Ketonen, Dieter J Meyerhoff, Robert E Lenkinski, R Gilberto Gonzalez, Bradford A Navia: A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis.. Journal of Magnetic Resonance Imaging 07/2003; 17(6):625-33.

Martha S Lappin, Fraser Wilson Lawrie, Todd L Richards, Eric D Kramer: Effects of a pulsed electromagnetic therapy on multiple sclerosis fatigue and quality of life: A double-blind, placebo controlled trial. Alternative therapies in health and medicine 07/2003; 9(4):38-48.

Hunterg Hoffman Ph. D, Todd Richards Ph. D, Barbara Coda M. D, Anne Richards B. S, Sam R. Sharar: The Illusion of Presence in Immersive Virtual Reality.

P.L. Lee, C.T. Yiannoutsos, T. Ernst, L. Chang, J. Jarvik, T. Richards, E. Kwok, D. Lu, J.R. McConnell, L. Ketonen, D. Meyerhoff, R.E. Lenkinski, B.A. Navia, R.G. Gonzalez: Design and validation of a multi-center proton MRS protocol for the study of the AIDS Dementia Complex. Journal of Magnetic Resonance Imaging 06/2003; 17:625-633.

Patricia Lani Lee PhD, Constantin T. Yiannoutsos PhD, Thomas Ernst PhD, Linda Chang MD, Christina M. Marra MD, Jeffrey G. Jarvik MD, Todd L. Richards PhD, Edmund W. Kwok PhD, PhD Dennis L. Kolson MD, David Simpson MD, Cheuk Y. Tang PhD, Giovanni Schifitto MD, PhD Leena M. Ketonen MD, Dieter J. Meyerhoff PhD, Robert E. Lenkinski PhD, PhD R. Gilberto Gonzalez MD, PhD Bradford A. Navia MD: A multi‐center 1H MRS study of the AIDS dementia complex: Validation and preliminary analysis. Journal of Magnetic Resonance Imaging 06/2003; 17(6):625 - 633., DOI:10.1002/jmri.10295

Hunter G Hoffman, Todd Richards, Barbara Coda, Anne Richards, Sam R Sharar: The Illusion of Presence in Immersive Virtual Reality during an fMRI Brain Scan. CyberPsychology & Behavior 05/2003; 6(2):127-31., DOI:10.1089/109493103321640310

Mark A Eckert, Christiana M Leonard, Todd L Richards, Elizabeth H Aylward, Jennifer Thomson, Virginia W Berninger: Anatomical correlates of dyslexia: frontal and cerebellar findings. Brain 03/2003; 126(Pt 2):482-94.

S D Friedman, D W Shaw, A.A. Artru, T L Richards, J Gardner, G Dawson, S Posse, S R Dager: Regional brain chemical alterations in young children with autism spectrum disorder. Neurology 02/2003; 60(1):100-7., DOI:10.1212/WNL.60.1.100

Leanna J Standish, L Clark Johnson, Leila Kozak, Todd Richards: Evidence of correlated functional magnetic resonance imaging signals between distant human brains. Alternative therapies in health and medicine 01/2003; 9(1):128, 122-5.

Todd L Richards, Virginia W Berninger, Elizabeth H Aylward, Anne L Richards, Jennifer B Thomson, William E Nagy, Joanne F Carlisle, Stephen R Dager, Robert D Abbott: Reproducibility of proton MR spectroscopic imaging (PEPSI): Comparison of dyslexic and normal-reading children and effects of treatment on brain lactate levels during language tasks. American Journal of Neuroradiology 11/2002; 23(10):1678-85.

Geraldine Dawson, Sara Webb, Gerard D Schellenberg, Stephen Dager, Seth Friedman, Elizabeth Aylward, Todd Richards: Defining the broader phenotype of autism: Genetic, brain, and behavioral perspectives. Development and Psychopathology 02/2002; 14(3):581-611., DOI:10.1017/S0954579402003103

Virginia W Berninger, Robert D Abbott, Sylvia P Abbott, Steve Graham, Todd Richards: Writing and Reading: Connections Between Language by Hand and Language by Eye. Journal of Learning Disabilities 01/2002; 35(1):39-56., DOI:10.1177/002221940203500104

Todd L. Richards: Functional Magnetic Resonance Imaging and Spectroscopic Imaging of the Brain: Application of fMRI and fMRS to Reading Disabilities and Education. Learning Disability Quarterly 08/2001; 24(3):189-203., DOI:10.2307/1511243

David P. Corina, Todd L. Richards, Sandra Serafini, Anne L. Richards, Keith Steury, Robert D. Abbott, Denise R. Echelard, Kenneth R. Maravilla, Virginia W. Berninger: fMRI auditory language differences between dyslexic and able reading children. Neuroreport 06/2001; 12(6):1195-201., DOI:10.1097/00001756-200105080-00029

S Serafini, K Steury, T Richards, D Corina, R Abbott, S R Dager, V Berninger: Comparison of fMRI and PEPSI during language processing in children. Magnetic Resonance in Medicine 03/2001; 45(2):217-25.

Sandra Serafini, Keith Steury, Todd Richards, David Corina, Robert Abbott, Stephen R. Dager, Virginia Berninger: Comparison of fMRI and PEPSI during language processing in children. Magnetic Resonance in Medicine 02/2001; 45(2):217 - 225., DOI:10.1002/1522-2594(200102)45:2<217::AID-MRM1030>3.0.CO;2-3

T L Richards, D Corina, S Serafini, K Steury, D R Echelard, S R Dager, K Marro, R D Abbott, K R Maravilla, V W Berninger: Effects of a Phonologically Driven Treatment for Dyslexia on Lactate Levels Measured by Proton MR Spectroscopic Imaging. American Journal of Neuroradiology 06/2000; 21(5):916-22.

Todd Richards, David P. Corina, Sandra Serafini, Keith Steury, Denise R. Echelard, Stephen Dager, Robert Abbott, Kenneth R. Maravilla, Virginia Berninger: Functional MRI and functional MR spectroscopic imaging of Dyslexia. NeuroImage 05/2000; 11(5)., DOI:10.1016/S1053-8119(00)91057-7

Seth D Friedman, Stephen R Dager, Todd L Richards, Helen Petropoulos, Stefan Posse: Modeling brain compartmental lactate response to metabolic challenge: A feasibility study. Psychiatry Research 03/2000; 98(1):55-66., DOI:10.1016/S0925-4927(99)00053-0

S Serafini, D Corina, K Steury, T Richards, R Abbott, C Hayes, V Berninger: MR spectroscopy during language processing in dyslexic and non-dyslexic children.. Journal of Cognitive Neuroscience 01/2000;

T L Richards, S R Dager, D Corina, S Serafini, AC Heide, K Steury, W Strauss, C E Hayes, R D Abbott, S Craft, D Shaw, S Posse, V W Berninger: Dyslexic children have abnormal brain lactate response to reading- related language tasks. American Journal of Neuroradiology 10/1999; 20(8):1393-8.

Carlos Vallbona, Todd Richards: Evolution of Magnetic Therapy from Alternative to Traditional Medicine. Physical Medicine and Rehabilitation Clinics of North America 09/1999; 10(3):729-54., DOI:10.1016/S1047-9651(18)30190-6

Stefan Posse, Stefan Wiese, Daniel Gembris, Klaus Mathiak, Christoph Kessler, M.L. Grosse-Ruyken, Barbara Elghahwagi, Todd Richards, Stephen R. Dager, Valerij G. Kiselev: Enhancement of BOLD-Contrast Sensitivity by Single-Shot Multi-Echo Functional MR Imaging. Magnetic Resonance in Medicine 08/1999; 42(1):87-97., DOI:10.1002/(SICI)1522-2594(199907)42:1<87::AID-MRM13>3.0.CO;2-O

KE Conley, ML Blei, TL Richards, MJ Kushmerick, SA Jubrias: Activation of glycolysis in human muscle in vivo (vol 42, pg C306, 1997). AJP Cell Physiology 03/1999; 276(3).

S R Dager, M E Layton, W Strauss, T L Richards, A Heide, S D Friedman, A.A. Artru, C E Hayes, S Posse: Human brain metabolic response to caffeine and the effects of tolerance. American Journal of Psychiatry 03/1999; 156(2):229-37., DOI:10.1176/ajp.156.2.229

Stephen R. Dager, Seth D. Friedman, Aaron Heide, Matthew E. Layton, Todd Richards, Alan Artru, Wayne Strauss, Cecil Hayes, Stefan Posse: Two-dimensional Proton Echo-Planar Spectroscopic Imaging of Brain Metabolic Changes During Lactate-Induced Panic. Archives of General Psychiatry 02/1999; 56(1):70-7., DOI:10.1001/archpsyc.56.1.70

Jonathan Newmark, Todd L. Richards: Delayed Unilateral Post-Traumatic Tremor: Localization Studies Using Single-Proton Computed Tomographic and Magnetic Resonance Spectroscopy Techniques. Military medicine 02/1999; 164(1):59-64., DOI:10.1093/milmed/164.1.59

S. Posse, S. Wiese, D. Gembris, K. Mathiak, C. Kessler, M.-L. Grosse-Ruyken, B. Elghahwagi, T. Richards, S.R. Dager, V.G. Kiselev: Enhancement of BOLD-contrast sensitivity of fMRI by single-shot spectroscopic imaging.

T L Richards, S R Dager, S Posse: Functional MR spectroscopy of the brain. Neuroimaging Clinics of North America 12/1998; 8(4):823-34.

James D. Bowen, Stephen H. Petersdorf, Todd L. Richards, Ken R. Maravilla, David C. Dale, Tom H. Price, Tom P.St. John, Albert S. Yu: Phase I study of a humanized anti-CD11/CD18 monoclonal antibody in multiple sclerosis*. Clinical Pharmacology & Therapeutics 10/1998; 64(3):339-46., DOI:10.1016/S0009-9236(98)90183-7

Todd L. Richards, Martha S. Lappin, Fraser W. Lawrie, Keith C. Stegbauer: Bioelectromagnetic Applications for Multiple Sclerosis. Physical Medicine and Rehabilitation Clinics of North America 09/1998; 9(3):659-74., DOI:10.1016/S1047-9651(18)30256-0

George H. Kraft, Todd L. Richards, Aaron C. Heide: Correlations of Evoked Potentials With Mr Imaging and Mr Spectroscopy in Multiple Sclerosis. Physical Medicine and Rehabilitation Clinics of North America 09/1998; 9(3):561-7, vi., DOI:10.1016/S1047-9651(18)30249-3

AC Heide, G H Kraft, J C Slimp, J C Gardner, S Posse, S Serafini, J D Bowen, T L Richards: Cerebral N-acetylaspartate is low in patients with multiple sclerosis and abnormal visual evoked potentials. American Journal of Neuroradiology 06/1998; 19(6):1047-54.

S. Posse, S. Wiese, C. Kessler, D. Gembris, U. Weiss, M. Peyer, M.L. Grosse-Ruyken, B. Elghawaghi, T. Richards, S. Dager: Functional MR Imaging of Visual and Olfactory Activation Using Quantitative T2’ - Mapping. NeuroImage 05/1998; 7(4):S445., DOI:10.1016/S1053-8119(18)31278-3

J Bowen, T Richards, K Maravilla: MR imaging and proton MR spectroscopy in A-to-G substitution at nucleotide position 3243 of leucine transfer RNA. American Journal of Neuroradiology 02/1998; 19(2):231-4.

S. Posse, S. Wiese, C. Kessler, D. Gembris, U. Weiss, M. Peyerl, M.L. Grosse-Ruyken, B. Elghawaghi, T. Richards, S. Dager: Functional MR imaging of visual and olfactory activation using quantitative T2*-mapping. Proc. 4th Annual Meeting of the Organization of Human Brain Mapping. NeuroImage 01/1998; 7(4).

S. Posse, S. Wiese, C. Kessler, D. Gembris, U. Weiss, M. Peyerl, M.L. Grosse-Ruyken, B. Elghawaghi, T. Richards, S. Dager: Single shot T2*-sensitive spectroscopic imaging increases fMRI sensitivity: preliminary evidence from visual and olfactory activation.

Stephen R Dager, Todd Richards, Wayne Strauss, Alan Artru: Dager SR, Richards T, Strauss W & Artru A.Single-voxel 1H-MRS investigation of brain metabolic changes during lactate-induced panic. Psychiatry Res 76: 89−99. Psychiatry Research 12/1997; 76(2-3):89-99., DOI:10.1016/S0925-4927(97)00066-8

TL Richards, SR Dager, HS Panagiotides, CE Hayes, S Posse, S Serafini, JA Nelson, KR Maravilla: Functional magnetic resonance spectroscopy during language activation - A preliminary study using proton echo-planar spectroscopic imaging. 11/1997; 3(6):490-495.

K E Conley, M L Blei, T L Richards, M J Kushmerick, SA Jubrias: Activation of glycolysis in human muscle in vivo. The American journal of physiology 08/1997; 273(1 Pt 1):C306-15., DOI:10.1152/ajpcell.1997.273.1.C306

Todd L. Richards, Aaron C. Heide, George H. Kraft, Jeff C. Slimp, Jill C. Gardner, Stefan Posse, Sandra Serafini, James D. Bowen: ABNORMAL MR SPECTROSCOPY AND NORMAL VISUAL EVOKED POTENTIALS IN MULTIPLE SCLEROSIS. Journal of Clinical Neurophysiology 07/1997; 14(4):350., DOI:10.1097/00004691-199707000-00025

Todd L. Richards, Jill C. Gardner, John W. Sundsten, George H. Kraft, Aaron C. Heide, Sandra Serafini, Jeff C. Slimp: REGISTRATION OF A 3D FUNCTIONAL/ANATOMICAL ATLAS WITH VOLUME MRI. Journal of Clinical Neurophysiology 07/1997; 14(4)., DOI:10.1097/00004691-199707000-00026

George H. Kraft, Jill C. Gardner, John W. Sunsten, Katrin Petersen, Todd Richards, Aaron Heide, Sandra Serafini, Jeff Slimp: CORRELATION OF EVOKED POTENTIAL DATA WITH MAGNETIC RESONANCE SPECTROSCOPIC IMAGING USING A 3D COMPUTERIZED ANATOMICAL ATLAS. Journal of Clinical Neurophysiology 07/1997; 14(4)., DOI:10.1097/00004691-199707000-00014

Stefan Posse, Stephen R. Dager, Todd L. Richards, Chun Yuan, Robert Ogg, Alan A. Artru, H W Müller-Gärtner, Cecil Hayes: In Vivo Measurement of Regional Brain Metabolic Response to Hyperventilation Using Magnetic Resonance: Proton Echo Planar Spectroscopic Imaging (PEPSI). Magnetic Resonance in Medicine 06/1997; 37(6):858-65., DOI:10.1002/mrm.1910370609

T L Richards, G A Gates, J C Gardner, T Merrill, C E Hayes, H Panagiotides, S Serafini, E W Rubel: Functional MR spectroscopy of the auditory cortex in healthy subjects and patients with sudden hearing loss. American Journal of Neuroradiology 05/1997; 18(4):611-20.

L M Rose, T L Richards, J Peterson, R Petersen, E C Alvord: Resolution of CNS lesions following treatment of experimental allergic encephalomyelitis in macaques with monoclonal antibody to the CD18 leukocyte integrin. Multiple Sclerosis 02/1997; 2(6):259-66., DOI:10.1177/135245859700200601

T L Richards, M S Lappin, J Acosta-Urquidi, G H Kraft, A.C. Heide, F W Lawrie, T E Merrill, G B Melton, C.A. Cunningham: Double-Blind Study of Pulsing Magnetic Field Effects on Multiple Sclerosis. The Journal of Alternative and Complementary Medicine 02/1997; 3(1):21-9., DOI:10.1089/acm.1997.3.21

S. Posse, S. Wiese, D. Behr, M.-L. Grosse-Ruyken, N.J. Shah, T. Richards, S. Dager, H.-W. Müller-Gärtner: Detection of brain activity by oxygenation sensitive proton echo planar spectroscopic imaging (PEPSI).

T.L. Richards, S.R. Dager, H.S. Panagiotides, C.E. Hayes, S. Posse, S. Serafini, J.A. Nelson, K.R. Maravilla: Functional magnetic resonance spectroscopy during language activation.

Dager S.R, Richards T.L, Marro K.I, Strauss W, Heidi A, Artru A.A, Posse S: 1H MRS investigation of panic disorder. Biological Psychiatry 04/1996; 39(7):609-609., DOI:10.1016/0006-3223(96)84313-7

SR Dager, M Layton, T Richards: Neuroimaging Findings in Anxiety Disorders.. Seminars in Clinical Neuropsychiatry 02/1996; 1(1):48-60., DOI:10.1053/SCNP00100048

Susan J. Astley, Edward Weinberger, Dennis W.W. Shaw, Todd L. Richards, Sterling K. Clarren: Magnetic resonance imaging in ethanol exposed Macaca nemestrina. Neurotoxicology and Teratology 09/1995; 17(5):523-30., DOI:10.1016/0892-0362(95)00012-G

Wayne L. Strauss MS, Jay S. Tsuruda MD, Todd L. Richards PhD: Partial volume effects in volume localized phased‐array proton spectroscopy of the temporal lobe. Journal of Magnetic Resonance Imaging 07/1995; 5(4):433 - 436., DOI:10.1002/jmri.1880050411

T.L. Richards, E.C. Alvord, Y He, K Petersen, J Peterson, S Cosgrove, A.C. Heide, K Marro, L.M. Rose: Experimental allergic encephalomyelitis in non-human primates: diffusion imaging of acute and chronic brain lesions. Multiple Sclerosis 07/1995; 1(2):109-17., DOI:10.1177/135245859500100209

S R Dager, W L Strauss, K I Marro, T L Richards, G D Metzger, AA. Artru: Proton magnetic resonance spectroscopy investigation of hyperventilation in subjects with panic disorder and comparison subjects. American Journal of Psychiatry 06/1995; 152(5):666-72., DOI:10.1176/ajp.152.5.666

T L Richards, E C Alvord, J Peterson, S Cosgrove, R Petersen, K Petersen, A C Heide, J Cluff, L M Rose: Experimental allergic encephalomyelitis in non-human primates: MRI and MRS may predict the type of brain damage. NMR in Biomedicine 04/1995; 8(2):49-58., DOI:10.1002/nbm.1940080202

Jilma V. Jiménez, Todd L. Richards, Aaron C. Heide, John R. Grierson, Eric G. Shankland: Incorporation of A Phosphonium Analogue of Choline Into The Rat Brain as Measured by Magnetic Resonance Spectroscopy. Magnetic Resonance in Medicine 03/1995; 33(3):285-92., DOI:10.1002/mrm.1910330302

M W Chang, E Wong, T Richards: Footwear and falls: a case involving new cowboy boots. Archives of Physical Medicine and Rehabilitation 12/1994; 75(11):1266-8.

L M Rose, T Richards, E C Alvord: Experimental allergic encephalomyelitis (EAE) in nonhuman primates: A model of multiple sclerosis. Laboratory animal science 11/1994; 44(5):508-12.

BR FINK, KR MARAVILLA, TL RICHARDS, R SLOAN: REGIONAL SPINAL CEREBROSPINAL-FLUID (CSF) VOLUMES. Anesthesiology 09/1994; 81(3A):A231-A231., DOI:10.1097/00000542-199409001-00231

S R Dager, K I Marro, T L Richards, G D Metzger: Preliminary application of magnetic resonance spectroscopy to investigate lactate-induced panic. American Journal of Psychiatry 02/1994; 151(1):57-63., DOI:10.1176/ajp.151.1.57

A C Heide, T L Richards, E C Alvord, J Peterson, L M Rose: Diffusion imaging of experimental allergic encephalomyelitis. Magnetic Resonance in Medicine 04/1993; 29(4):478-84., DOI:10.1002/mrm.1910290409

SR DAGER, KI MARRO, G METZGER, TL RICHARDS: PROTON MAGNETIC-RESONANCE SPECTROSCOPY INVESTIGATION OF LACTATE-INDUCED PANIC. Biological Psychiatry 03/1993; 33(6A):A44-A44.

S.R. Dager, K.I. Marro, T.L. Richards, G.D. Metzger: MRS detection of whole brain lactate rise during 1 M sodium lactate infusion in rats. Biological Psychiatry 12/1992; 32(10):913-21., DOI:10.1016/0006-3223(92)90180-8

B. R. Fink, R. Gertach, T. Richards, K. R. Maravilla: Improved magnetic resonance (MR) imaging method for measurement of spinal fluid volume in normal subjects. Use of fast spin echo pulse sequence. Anesthesiology 09/1992; 77(Supplement)., DOI:10.1097/00000542-199209001-00875

S.R. Dager, K.I. Marro, T.L. Richards, G.D. Metzger: Localized magnetic resonance spectroscopy measurement of brain lactate during intravenous lactate infusion in healthy volunteers. Life Sciences 02/1992; 51(12):973-85., DOI:10.1016/0024-3205(92)90404-D

Yuhchyau Chen, Todd L. Richards, Seth Izenberg, Robert N. Golden, David L. Williams, James A. Nelson, R. Grant Steen: In vivo phosphorus NMR spectroscopy of skin using a crossover surface coil. Magnetic Resonance in Medicine 01/1992; 23(1):46-54., DOI:10.1002/mrm.1910230107

T L Richards: Proton MR spectroscopy in multiple sclerosis: Value in establishing diagnosis, monitoring progression, and evaluating therapy. American Journal of Roentgenology 12/1991; 157(5):1073-8., DOI:10.2214/ajr.157.5.1927795

Todd L. Richards: 1H NMR Spectroscopic Imaging of the Monkey Brain Using Binomial Water Suppression in a Stimulated-Echo Sequence. NMR in Biomedicine 08/1991; 4(4):187-91., DOI:10.1002/nbm.1940040406

Lynn Massman Rose, Todd L. Richards, Rosemarie Petersen, Jeff Peterson, Sarka Hruby, Ellsworth C. Alvord: Remitting-relapsing EAE in nonhuman primates: A valid model of multiple sclerosis. Clinical Immunology and Immunopathology 05/1991; 59(1):1-15., DOI:10.1016/0090-1229(91)90077-N

P. R. Gavin, S. L. Kraft, C. E. De Haan, M. P. Moore, C. W. Leathers, T. L. Richards, W. F. Bauer, L. R. Wendling: The magnetic resonance and computed tomography features of canine brain tumors following boron neutron capture therapy. International Journal of Radiation OncologyBiologyPhysics 12/1990; 19(1):268-268., DOI:10.1016/0360-3016(90)90926-B

Todd L. Richards: Separation of Lipids from Lactate in Experimental Allergic Encephalomyelitis by Zero Quantum NMR Techniques. Investigative Radiology 01/1990; 24(12):955-7., DOI:10.1097/00004424-198912000-00006

TL Richards, KM Bradshaw, D Flaming: Boron11 Chemical Shift Imaging of BNCT compound in Aqueous Albumin Solutions. Investigative Radiology 12/1989; 24(12)., DOI:10.1097/00004424-198912000-00094

TL Richards, RN Golden, EG Shankland, LM Rose, J Peterson: High Signal Intensity Near Magnetite Microspheres Measured with Magnetic Resonance Imaging. Investigative Radiology 12/1989; 24(12)., DOI:10.1097/00004424-198912000-00067

R L Baron, W P Shuman, S P Lee, C. A. Rohrmann, R N Golden, T L Richards, M L Richardson, J. A. Nelson: MR appearance of gallstones in vitro at 1.5 T: Correlation with chemical composition. American Journal of Roentgenology 09/1989; 153(3-3):497-502., DOI:10.2214/ajr.153.3.497

J C Livesey, R N Golden, E G Shankland, Z Grunbaum, T L Richards, R A Wade, K A Krohn: Measurement of tissue oxidation-reduction state with carbon-13 nuclear magnetic resonance spectroscopy. Cancer Research 05/1989; 49(8):1937-40.

L.M. Rose, T.L. Richards, E.C. Alvord: Magnetic resonance imaging and peripheral blood abnormalities in experimental allergic encephalomyelitis. Biomedicine & Pharmacotherapy 02/1989; 43(5):347-53., DOI:10.1016/0753-3322(89)90060-7

T L Richards, K M Bradshaw, D M Freeman, C H Sotak, P R Gavin: Imaging with 11B of Intact Tissues Using Magnetic Resonance Gradient Echoes. Strahlentherapie und Onkologie 02/1989; 165(2-3):179-81.

Todd L. Richards: MR Appearance of Gallstones in Vitro at 1.5 T: Correlationwith Chemical.

Todd Richards, Thomas F. Budinger: NMR Imaging and Spectroscopy of the Mammalian Central Nervous System after Heavy Ion Radiation. Radiation Research 02/1988; 113(1):79-101., DOI:10.2307/3577182

TODD L. RICHARDS, CRAIG A. DAVIS, BRUCE R. BARKER, WOLF D. BEINERT, HARRY K. GENANT: Lipid/ Water Ratio of Bone Marrow Measured by Phase-Encoded Proton Nuclear Magnetic Resonance Spectroscopy. Investigative Radiology 10/1987; 22(9):741-6., DOI:10.1097/00004424-198709000-00008

T L Richards, M A Keniry, P R Weinstein, B M Pereira, B T Andrews, E J Murphy, T L James: Measurement of lactate accumulation byin Vivo proton NMR spectroscopy during global cerebral ischemia in rats. Magnetic Resonance in Medicine 10/1987; 5(4):353-7., DOI:10.1002/mrm.1910050406

T L Richards, F Terrier, R E Sievers, M J Lipton, M E Moseley, C B Higgins: Lactate accumulation in ischemic- and anoxic-isolated rat hearts assessed by H-1 spectroscopy. Investigative Radiology 09/1987; 22(8):638-41.

TODD L. RICHARDS, FRANCOIS TERRIER, RICHARD E. SIEVERS, MARTIN J. LIPTON, MICHAEL E. MOSELEY, CHARLES B. HIGGINS: Lactate Accumulation in Ischemic and Anoxic-Isolated Rat Hearts Assessed by Hl Spectroscopy. Investigative Radiology 08/1987; 22(8):638-641., DOI:10.1097/00004424-198708000-00004

T Richards, D Tscholakoff, C B Higgins: Proton NMR spectroscopy in canine myocardial infarction. Magnetic Resonance in Medicine 07/1987; 4(6):555-66.

Todd Richards, Dimiter Tscholakoff, Charles B. Higgins: Proton NMR spectroscopy in canine myocardial infarction. Magnetic Resonance in Medicine 06/1987; 4(6):555 - 566., DOI:10.1002/mrm.1910040606

T. L. Richards, C. A. Davis, B. R. Barker, W. D. Beinert, H. K. Genant: 148 LIPID/WATER RATIO OK BONE MARROW MEASURED BY PHASE-ENCODED PROTON NMR SPECTROSCOPY. Investigative Radiology 09/1986; 21(9)., DOI:10.1097/00004424-198609000-00166

George E. Wesbey, Ralph Hurdt, Martin J. Lipton, Todd Richards, Michael E. Moseley, Charles B. Higgins: 118 IN VIVO HUMAN SKELETAL, MUSCLE ISCHEMIA DEISCTED BY THE CHEMICAL SHIFT OF BIOLOGICAL WATER. Investigative Radiology 09/1985; 20(6)., DOI:10.1097/00004424-198509000-00146

Michael E. Moseley, Wil M. Chew, Merry C. Nishimura, Todd L. Richards, Joseph Murphy-Boesch, Gregory B. Young, Thomas M. Marschner, Lawrence H. Pitts, Thomas L. James: In vivo sodium-23 magnetic resonance surface coil imaging: Observing experimental cerebral ischemia in the rat. Magnetic Resonance Imaging 02/1985; 3(4):383-7., DOI:10.1016/0730-725X(85)90402-3

T. Richards: NMR imaging and spectroscopy of the mammalian central nervous system after heavy ion radiation. 1988, DOI:10.2172/6268623

T. Richards, T. Budinger, R. Nunlist: Proton NMR relaxation times of gray and white matter before and after tissue preservation.

G.T.Y. Chen, S. Pitluck, T. Richards, J.R. Castro, J.M. Quivey, W.M. Saunders, J.T. Lyman: Utility of three dimensional display of CT derived contours in charged particle treatment planning. International journal of radiation oncology, biology, physics 09/1981; 7(9):1250-1251., DOI:10.1016/0360-3016(81)90584-8

Patents

Aaron G Filler, Jay S. Tsuruda, Todd L. Richards, Franklyn A. Howe: Image Neurography and Diffusion Anisotropy Imaging. Ref. No: US 5,560,360, Year: 10/1996

Conference Proceedings

Ralph Elkins, Kalyan Dandala, Richard Repass, Robert Nieson, Todd Richards, Hunter Hoffman: fMRI brain scans of a patient's transition from pre-treatment alcohol related craving activations to post-treatment alcohol related aversion activations following hypnotic coveret sensirization plus emetic (chemical aversion) counter conditioning for alcohol use disordeer.. 2014 Annual Meeting of the Society for Clinical and Experimental Hypnosis, San Antonia, Texas; 10/2014

N. M. M. Kleinhans, T. L. Richards, J. Greenson, G. Dawson, E. H. Aylward: Neural Habituation in Response to Emotional Faces and Houses in ASD. 2014 International Meeting for Autism Research; 05/2014

S. R. Dager, N. M. Corrigan, T. Richards, D. Dunner, I. K. Lyoo, P. F. Renshaw: Imaging brain metabolism: evidence for altered brain bioenergetics in bipolar disorder. 16th Annual Conference of the; 03/2014

Donna Jean Cross, Rodney Ho, Todd L. Richards, Vasily L. Yarnykh, Greg Garwin, Pierre Mourad, David Cook, Satoshi Minoshima: Imaging Biomarker Evaluation of Cytoskeletal Stabilization Therapy for Traumatic Brain Injury. Radiological Society of North America 2013 Scientific Assembly and Annual Meeting; 12/2013

S. C. Huang, G. J. Pauley, T. L. Richards, N. M. Corrigan, D. W. Shaw, A. A. Artru, A. Estes, S. Dager, N. M. Kleinhans: Developmental Differences in the Uncinate Fasciculus Vary by Sex in Autism Spectrum Disorders. 2013 International Meeting for Autism Research; 05/2013

Nathalie M. Martin, Donna Jean Cross, Eric C. Petrie, Todd L. Richards, Kenneth R. Maravilla, Satoshi Minoshima: Metabolic Changes Associated with White Matter Dysintegrity and Grey Matter Volume in Mild Cognitive Impairment as Characterized by FDG-PET, DTI-MRI, and MRI Morphometry. Radiological Society of North America 2012 Scientific Assembly and Annual Meeting; 11/2012

Nathalie M Martin, Donna Jean Cross, Eric C Petrie, Todd L. Richards, Satoshi Minoshima: Metabolic Changes Associated with White Matter Dysintegrity in Mild Cognitive Impairment as Characterized by DTI-MRI and FDG-PET. Radiological Society of North America 2011 Scientific Assembly and Annual Meeting; 11/2011

Dean Kazuo Shibata, Todd L. Richards, Yoshimi Anzai: Diffusion Tensor Radial Diffusivity Histogram Parameters Correlate with Severity in Multiple Sclerosis. Radiological Society of North America 2010 Scientific Assembly and Annual Meeting; 12/2010

N. M. Kleinhans, T. R. Richards, C. Johnson, J. Greenson, G. Dawson, E. H. Aylward: fMRI evidence of reduced emotional face processing automaticity in autism spectrum disorders. International Meeting for Autism Research 2008; 05/2008

E. H. Aylward, N. M. Kleinhans, T. R. Richards, C. Johnson, J. Greenson, G. Dawson: Association Between Amygdala Activation in Response to Emotional Faces and Social Anxiety in ASD. International Meeting for Autism Research 2008; 05/2008

Published Abstracts/Presentations:

2013-2014

Berninger, V., Richards, T., Grabowksi, T., Askren, K., Boord, P., Yagle, K., Mestre, Z., (2014, February 19). Understanding the writing brain from the perspective of the human connectome: Structural and functional connectivity in transcription and translation. In S. Hooper (organizer). Writing across the lifespan: Advances in the neurological underpinnings, measurement, and intervention, Writing Research across the Borders III, Paris, France.

Richards, T. and Berninger V.W., Update from the University of Washington Learning Disabilities Center and research activity, NIH meeting on Learning Disabilities, Florida, 2013.

Reitz , F., Richards, T., Wu, K., Boord, P., Askren, K., Lewis, T., & Berninger, V. (2013). An MRI-compatible, computer-interfaced drawing pad, Human Brain Mapping annual meeting, 2013

Richards, T., Grabowski, T., Askren, K., Collins, E., Gulliford, D., Welker, O., & Berninger, V. (2013, June 18, 1:30-3:30 pm). Children with dyslexia/dysgraphia and DTI parameter correlations with single word reading. Human Brain Mapping annual meeting, 2013

Richards, T., Grabowski, T., Askren, K., Boord, P., Yagle, K., Mestre, Z., Reitz, F., Welker, O., Guilford, D., Young, L., Collins, E., & Berninger, V. (2013, November 8, 10:00 to noon). Functional and structural connectivity across levels of language in children with dysgraphia. Poster Session D70 Society of Neurobiology of Language. San Diego, CA.

Richards, T, T. Grabowski, V. Berninger, Brain Connections and Systems Biology in the Study of Learning Disabilities, Conference on Systems Biology, Seattle, WA 2013.

2005-2006

T. Richards, N. Oskin, H. Panagiotides, S. Webb, A. Poliakov, N. Kleinhans, E. Aylward, G. Dawson, Face Processing in Autism: fMRI/EEG source localization correlations, International Meeting for Autism Research, 2006

N. Oskin, S. Webb, T. Richards, H. Panagiotides, E. Aylward, DIPOLE SOURCE LOCALIZATION OF FACE PROCESSING IN AUTISM, International Meeting for Autism Research, 2006

Natalia Kleinhans, Todd Richards, Clark Johnson, KC Stegbauer, Geraldine Dawson, Elizabeth Aylward, Abnormal amygdala-fusiform connectivity in autism spectrum disorders during face processing, International Meeting for Autism Research, 2006

Richards, TL et al, Differences in fMRI Activation between Children with and without Dyslexia during Pseudoword Aural Repeat and Visual Decode, Annual Meeting for Cognitive Neuroscience Society, San Francisco, 2006

Todd Richards, Neva Oskin, Heracles Panagiotides, Sara Webb, Andrew Poliakov, Elizabeth Aylward, Geraldine Dawson, Face Processing in Autism: Spatial-temporal localization of fusiform activation, Annual Meeting for Human Brain Mapping, Toronto, Canada, 2005

1998-2000

Serafini S, Corina D, Richards T, Heide A, Dager S, Posse S, Hayes C, Berninger V. Functional MR Spectroscopy as a Tool to Investigate Language Processing. Cognitive Neuroscience Society 1998 Annual Meeting Abstract Program, p.124. Presented as a poster at the Cognitive Neuroscience Society Fifth Annual Meeting April 5-7, 1998, San Fransisco, CA.

S. Serafini, K. Steury, B. Floyd, D. Corina, T. Richards, S. Dager, S. Posse, C. Hayes, V. Berninger, Comparison of MR spectroscopy and functional MRI during language processing in children, Cognitive Neuroscience Society 1999 Annual Meeting Abstract Program, abstract 57b, Presented as a poster at the Cognitive Neuroscience Society Sixth Annual Meeting April 10-13, Washington, DC.

Berninger V, Richards T, Corina D, Serafini S, Abbott R, Treatment-related changes in chemical activation of dyslexic brains during phonological and lexical access tasks, Society for the Scientific Study of Reading, Montreal, April, 1999.

Richards TL, Corina D, Serafini S, Steury K, Echelard DR, Dager SR,, Marro K, Maravilla, KR, Abbott RD, Berninger VW, Functional MRI and functional MR spectroscopic imaging of dyslexia, accepted to Human Brain Mapping 2000, San Antonio Conference, June 2000.

Steury K, Corina D, Richards T, Serafini S, Maravilla K, A comparison of fMRI and fMRS during an auditory monitoring task, submitted to Cognitive Neuroscience Society Meeting 2000.

1997

Corina DP, Craft S, Serafini S, Richards TL, Dager SR, Posse S,

Hayes CE, Berninger V. A Functional MR Spectroscopy Study of Language

Processing. Cognitive Neuroscience 4th Annual meeting, Boston, MA, 1997.

American Academcy of Clinical Neurophysiology, oral presentation, 1- 1st author, 1- coauthor,

Berninger, V., Raskind, W., Dager, S., Richards, T., Corina, D., Abbott, R., & McCutchen, D. (1997, April 21). Treatment of reading and writing disabilities. Annual meeting of the Learning Disabilities Association, Chicago.

International Society for Magnetic Resonance in Medicine, Annual Meeting, 1997, 2 coauthor presentations

1996

American Academy of Neurology, oral presentation, 1996.

American Society of Neuroradiology, 34th Annual Meeting, 1st author, 2 co-author, 1996

International Society of Magnetic Resonance in Medicine, 2- coauthor, 1996

Clinical Neurophysiology, 1-coauthor, 1996

1995

1. TL Richards, MR spectroscopy for evaluating metabolic changes in the brain of MS patients, International Business Communications, Conference on Multiple Sclerosis, 1995.

1994 - 5

Abstracts, 2nd Annual Meeting, Society of Magnetic Resonance, 1994

TL Richards, LM Rose, K Maravilla, EC Alvord Jr, CA Cunningham, JD Bowen, Multiple sclerosis: abnormally low N-acetyl/creatine ratio in central gray matter, Abstracts, 2nd Annual Meeting, Society of Magnetic Resonance, p. 591, 1994

11:18 190. 1H MRS Investigation of Hyperventilation in Panic and Control Subjects. S.R.Dager, K.I. Marro, W. Strauss, T.L. Richards and A.A. Artru. University of Washington, Seattle.

5:12 402. Partial Volume Effects in Human Temporal Lobe Proton Magnetic Resonance Spectroscopy. W.L. Strauss, J.S. Tsuruda and T.L. Richards. University of Washington Medical Center, Seattle.

S-02-1624TH 1158. Diffusion-Weighted Fluorine Spectroscopy. E.G. Shankland, T.L. Richards and K.A. Krohn. University of Washington, Seattle.

S-05-1615T 1425. Incorporation of a Phosphonium Ana­logue of Choline into the Rat Brain as Measured by NMR Spectroscopy. J.V. Jimenez, T.L. Richards, A.C. Heide, J.R. Grierson and E.G. Shankland. University of Washington, Seattle.

1993

1. TL Richards, J Peterson, S Cosgrove, K Petersen, LM Rose, EC Alvord Jr, Temporal relationships in N-acetyl aspartate, choline, and MRI lesions in EAE, Conference proceedings, Advances in understanding and treatment of multiple sclerosis, International Business Communications, 1993.

2. E Weinberger, SJ Astley, TL Richards, DW Shaw, SK Clarren, Hydrogen proton spectroscopy in nonhuman primates exposed to ethanol during gestation, The Society for Pediatric Radiology, 36th Annual Meeting, 1993.

3. EC Alvord, C Shaw, T Richards, The relative rates of cellular proliferation and infiltration and the histologic definition of gliomas, in press, Canad J Neur Sci, 1993.

4. Chang MW, TL Richards, New cowboy boots make it hard to swallow: a case report of severe dysphagia from a fall, American Academy of Physical Medicine and Rehabililation, Annual Meeting, 1993.

5. TL Richards, C Yuan, CR Loomis, VP Terry, JS Tsuruda, JD Bowen, Progress towards N-acetyl aspartate imaging of the entire brain, Radiologic Society of North America, 1993 Annual Meeting.

6. AG Filler, RN Golden, FA Howe, JS Tsuruda, TL Richards, High resolution diffusion gradient imaging for neurography in human subjects, Society of Magnetic Resonance in Medicine, 1993 Annual Meeting.

7. EG Shankland, TL Richards, KA Krohn, C-13 flow suppression spectroscopy to measure cellular redox, SMRM, 1993 Annual Meeting.

8. SR Dager, KI Marro, TL Richards, GD Metzger, H-1 MRS investigation of lactate-induced panic, SMRM, 1993 Annual Meeting.

1992

1. TL Richards, AC Heide, K Marro, EC Alvord, J Peterson, LM Rose, Volume-localized proton NMR spectroscopy and histologic evaluation of demyelination in the monkey brain, Advances in Proton Magnetic Resonance Spectroscopy of the Brain, Society of Magnetic Resonance in Medicine, Oxford England, 1992.

2. TL Richards, J Tsuruda, AC Heidi, Vector analysis of diffusion images in experimental allergic encephalomyelitis, Society of Magnetic Resonance in Medicine, 11th Annual meeting, Berlin, 1992.

3. SR Dager, KI Marro,TL Richards, GD Metzger, 1H MRS detection of increased brain lactate during intravenous lactate infusion in humans, Society of Magnetic Resonance in Medicine, 11th Annual meeting, Berlin, 1992.

4. KI Marro, SR Dager, TL Richards, Attenuation of lactate signal due to coherent flow in volume localized MR spectroscopy, Society of Magnetic Resonance in Medicine, 11th Annual meeting, Berlin, 1992.

5. KI Marro, CE Hayes, TL Richards, An inductively driven 200 MHz bird-cage resonator with built-in variable tuning capacitors, Society of Magnetic Resonance in Medicine, 11th Annual meeting, 1992.

6. E Weinberger, D Shaw, S Ashley, TL Richards, 1H MR spectroscopy of an animal model of fetal alcohol syndrome, Society of Magnetic Resonance in Medicine, 11th Annual meeting, Berlin, 1992.

1982-1990

1. TL Richards, AC Heide, K Marro, LM Rose, JR Peterson, R Petersen, EC Alvord, Jr., Changes in brain proton spectra precede the onset of experimental allergic encephalomyelitis in macaques, Society of Magnetic Resonance in Medicine, Tenth Annual meeting, San Francisco, 1991, pp 427.

2. AC Heide, TL Richards, LM Rose, JP Peterson, EC Ellsworth Jr., Diffusion Imaging of Monkeys with Experimental Allergic Encephalomyelitis, Society of Magnetic Resonance in Medicine, Tenth Annual meeting, San Francisco, 1991, pp. 989

3. TL Richards, JR Peterson, LM Rose, EC Alvord Jr., Proton chemical shift imaging of primates during experimental allergic encephalomyelitis, Society of Magnetic Resonance in Medicine, Ninth Annual meeting, New York, Aug 18-24, 1990, pp. 1043.

4. TL Richards, U Schmiedl, Dynamic changes of proton resonances in the monkey brain following administration of gadolinium, Society of Magnetic Resonance in Medicine, Ninth Annual meeting, New York, Aug 18-24, 1990, pp. 1041.

5. Richards TL, KM Bradshaw, Boron-10 versus Boron-11 Signal to Noise Comparison of Compound used in Neutron Capture Therapy, Society of Magnetic Resonance in Medicine, Eighth Annual meeting, Amsterdam, Aug 21-26, 1989, pp. 300.

6. Richards TL, RN Golden, EG Shankland, LM Rose, J Peterson, High signal intensity near magnetite microspheres measured with magnetic resonance imaging, Invest. Radiol. 24, S90, 1989.

7. Richards TL, KM Bradshaw, D Flamig, Boron chemical shift imaging of BNCT compound in aqueous albumin solutions, Invest. Radiol. 24, S97, 1989.

8. Richards TL, JS Kenney, LM Rose, J Hill, S Hruby, R Petersen, EC Alvord Jr, Detection of Brain Lipids in primates with experimental allergic encephalomyelitis by in vivo proton spectroscopy and in vitro histochemistry, Society of Magnetic Resonance in Medicine, Seventh Annual meeting, San Francisco, Aug 21-26, 1988, pp. 467.

9. Kenney JS, TL Richards, Where in the Macaca Fascicularis brain is the localized proton spectrum uncontaminated by resonances in the 1.25+.2 ppm region?, Society of Magnetic Resonance in Medicine, Seventh Annual meeting, San Francisco, Aug 21-26, pp. 468., 1988

10. Golden RN, JC Livesey, EG Shankland, Z Grunbaum, TL Richards, RA Wade, KA Krohn, C-13 NMR tracer technique for in vivo measurement of tissue redox state, Society of Magnetic Resonance in Medicine, Seventh Annual meeting, "Works in Progress", pp. 70, 1988.

11. Richards TL, KM Bradshaw, DM Freeman, CH Sotak, PR Gavin, Boron-11 imaging of intact tissues using magnetic resonance gradient echos, Third International Symposium on Neutron Capture Therapy, Bremen, Germany, June, 1988.

12. Richards TL, PR Gavin, S Kraft, ML Griebenow, RN Golden, Boron-11 NMR spectroscopy of excised mouse tissues after infusion of boron compound used in neutron capture therapy, Radiology, 165(P), 346, 1987.

13. Richards TL, LM Rose, Rn Golden, EC Alvord, In vivo proton spectroscopy of the primate brain after induction of experimental allergic encephalomyelitis, "Works in Progress", Society of Magnetic Resonance in Medicine, Sixth Annual meeting, New York, Aug 17-21, pp. 64, 1987.

14. Golden RN, EG Shankland, Z Grumbaum, JC Livesey, TL Richards, RA Wade, KA Krohn, Measurement of Tissue Redox State with C-13 NMR, Conference on "Prediction of Tumor Treatment Response", April 21-24, 1987, Banff, Canada.

15. Williams D, D Olson, B Porter, T Richards, G Wesbey, Implanted dual coaxial transmission line balanced-matching approach to NMR probe design for canine myocardial NMR spectroscopy, Society of Magnetic Resonance in Medicine, Fifth Annual Meeting, August 19-22, 1986, Montreal, Canada, pp. 185-186.

16. Haynor DR, TL Richards, W See, G Wesbey, Perfluorocarbons for detection of tissue perfusion use of pulsed field gradients, Society of Magnetic Resonance in Medicine, Fifth Annual Meeting, August 19-22, 1986, Montreal, Canada, pp. 325-326.

17. See WA, T Richards, LA Mack, WH Chapman, GE Wesbey, P-31 NMR spectroscopy as a predictor of testicular viability following ischemic injury, Society of Magnetic Resonance in Medicine, Fifth Annual Meeting, August 19-22, 1986, Montreal, Canada, pp. 1013-1014.

18. Koretsky, Ap, T. Richards, ME Moseley, Spatial localization of metabolites using spin-echo difference spectroscopy, Society of Magnetic Resonance in Medicine, Fourth Annual Meeting, August 19-23, 1985, London, United Kingdom, pp. 999-1000, 1985.

19. Richards, T., T. F. Budinger, and R. Nunlist, Phase encoded proton spectroscopy and imaging of the rat brain in vivo with the surface coil, In: Scientific program, Society of Magnetic Resonance in Medicine, Third Annual Meeting, August 13-17, 1984, New York, New York, pp. 621-622, 1984.

20. Richards, T., T. F. Budinger, and R. Nunlist, RF pulse energy optimization for proton spectroscopy using lipid and n-acetyl aspartate peak characteristics of normal brain, In: Scientific program, Society of Magnetic Resonance in Medicine, Third Annual Meeting, August 13-17, 1984, New York, New York, pp. 623-624, 1984.

21. Jones, R. M., T. Richards, and T. F. Budinger, Proton and Carbon Spectroscopy of Lipids and Aqueous Metabolites Extracted from Brain, In: Scientific program, Society of Magnetic Resonance in Medicine, Third Annual Meeting, August 13-17, 1984, New York, New York, pp. 395-396, 1984.

22. Richards, T., T. F. Budinger, G. Wesbey, B. Engelstad, Evaluation of Heavy Ion Radiation Damage to the Rat Brain using Proton NMR Imaging, In: Scientific program, Society of Magnetic Resonance in Medicine. Second Annual Meeting, pp. 198-99, 1983.

23. Richards, T., A. Hasenfeld, and T. F. Budinger, A Computer Simulation of Surface Coil Selective Region Spectroscopy, In: Works in Progress, Society of Magnetic Resonance in Medicine. Second Annual Meeting, pp. 20, 1983.

24. Richards, T. L., T. F. Budinger, and R. Nunlist, Proton NMR Relaxation Times of Gray and White Matter before and after Tissue Preservation, In: Scientific program, Society of Magnetic Resonance in Medicine. First Annual Meeting, pp. 131-32, 1982.

25. Richards, T., G. T. Y. Chen, J. Llacer, C. A. Tobias, Determination of the Effects of Respiration on Charged Particle Radiotherapy of Abdominal Tumors, Med. Phys. 9:623, 1982.

Invited Presentations:

Brain Imaging and Language, UW Neurocognitive Institute, August 2012

Functional Magnetic Resonance Imaging and Electroencephalographic Evidence of Correlated Brain Signals Between Physically and Sensory Isolated Subjects, presented by invitation to the Society for Scientific Exploration, 27^th Annual Meeting, June 23-28, 2008

Brain imaging and spectroscopy: multiple sclerosis, Making connections - High School teacher training, 1994 - 2000

Techniques for automatic brain lesion detection in patients with multiple sclerosis, University of British Columbia, April, 1995

Magnetic resonance imaging and spectroscopy of multiple sclerosis, University of Utah, December, 1994.

Update on MS research, Bellevue MS support group, 1994, 1995, 1996

Update on MS research, Edmonds MS support group, 1994, 1995, 1996

Update on MS research, Everett MS support group, 1994, 1995

Update on MS research, Seattle MS support group, 1994, 1995,1996, 1997

Update on MS research, National Multiple Sclerosis Society, Local Chapter, Annual Meeting, 1994.

Magnetic resonance imaging and spectroscopy of the monkey brain during experimental allergic encephalomyelitis, Florida State University, Tallahasee, Florida, October 16, 1992.

"Brain lipids become NMR visible after experimental allergic encephalomyelitis" at the "MR Spectroscopy in Humans" Symposium of the American Physiological Society , Rochester, MN, October 16-19, 1989.

"Diffuse Brain Abnormalities", AUR Research Symposium, MRS: new insights into organ physiology, May 20-21, Seattle, Washington, 1989.

Spectroscopy Evening Workshop, SMRI 7th Annual meeting, New Visions, Feb 25- March 1, Los Angeles, 1989.

"Proton in vivo spectroscopy of CNS changes associated with radiation", given at: Workshop on Pathophysiological Studies by NMR In Vivo Spectroscopy, University of California, Berkeley, sponsored by the Society of Magnetic Resonance in Medicine, August 15, 1983

"NMR in-vitro spectroscopy with protons, phosphorus, and carbon on brain tissue", given at: Electrical Engineering Department Seminar, University of Utah, April 11, 1983

Inventions filed with the Office of Technology Transfer or UWC4C

Automatic detection of brain lesions on MR images, 1992

NMR detection of Cancer cell response to artemisinin, 2007

Software for characterization of sarcoma boundary, 2011

MRI-Compatible Real-Time Handwriting Digitization System, and has assigned 46248 as the UWC4C tracking number., 2012

Patent applications

Magnetic Resonance Neurography, 1993

Press Releases

UW Press release April 10, 1997 - Alternative medicine treatment using pulsing magnetic device may offer benefits for some MS patients

UW Press release, October, 1999 - Dyslexic children use nearly five times the brain area

http://www.washington.edu/newsroom/news/1999archive/10-99archive/k100499a.html

Newsweek article on our research - November 21, 1999