Associate Professor of Biostatistics, University of Washington
Education
Academic Awards and Scholarships
- 2008 Gertrude Cox Award for contributions to Statistical Practice,
from
Washington (DC) Statistical Society and RTI International
- Biometric Society (WNAR) Student Paper Competition 1997. Best Oral Presentation.
- Donovan J Thompson Award for Academic Excellence in Biostatistics (1996)
- Howard Hughes Medical Institute Predoctoral Fellowship (1995-1998)
- Commonwealth Scholarships and Fellowships Plan scholarship (1992-3)
- Faculty of Science Faculty Scholar, Monash University (1987-90)
Professional Memberships
Research Interests
- Regression modelling of correlated data, particularly discrete data:
- Clinical trials: ethical and statistical issues in design, conduct and
analysis.
- Semiparametric inference and connections to design-based inference
- Statistical computing: tools for programming, data analysis and teaching.
- Foundations: transitivity of tests, decision-theoretic constructions
of useful frequentist estimators.
- Genomics: design and analysis of large-scale association studies.
Teaching
- Spring 1999, 2001 Correlated Data Regression for
Epidemiology (new
course)
- Fall 1999, 2000, 2005 Advanced Applied Linear Models
- Winter 2000 Martingales for Survival Analysis
- Fall 2001, Winter 2002, Fall 2002, Spring 2006 Data Analysis
- Spring 2002, 2003 Advanced Theory of Statistical Inference
III
- Fall 2002, Summer 2003, Spring 2004 Statistical Consulting
- Fall 2003 Applied Biostatistics I
- Fall 2004 Survival Analysis
- Fall 2004, 2005, 2006 Introductory Statistical Computing in
R
(new course)
- Winter 2005 Visual Display of Quantitative Data (new course)
- Fall 2006 Advanced Design-Based Inference (new course)
- Spring 2007, 2008 Statistical Computing I
- Winter 2008 Sample Survey Techniques
- MS thesis supervision: Linn Abraham (2000), Chris Slaughter (2000), Kristian Lynch (current)
- PhD supervision: Petra Miksova (2004), Hyoju Chung (2006), Kristin
Berry (current)
- Director of the Training Program in
Cardiovascular Biostatistics
University Service
- Department
- Educational Policy and Teaching Evaluation (1999-2005, Chair
2000-2005)
- Computing Policy (2003-present, Chair since 2005).
- Admissions (1996,1998-present)
- Core Curriculum (1999-2005)
- Ad hoc committee for service curriculum revision (2000-01)
- Fall 2000 seminar series organiser
- Joint Stat/Biostat PhD Theory exam (1999, Chair 2005, 2007), PhD
Applied Exam (2000,
2002), MS Theory exam (2002, 2007)
- Other
- School of Public Health Curriculum Committee (1999-2005)
- NRCSE seminar organiser, Fall 1998
- Faculty Senate, 2001-2
Other Professional Activities
- Member of AAMM (monitoring methods) subcommittee of EPA Clean Air
Scientific Advisory Committee.
- Developed and taught short courses on data analysis and programming,
and survey analysis in R
- Taught in the Summer Institute in Statistical Genetics (Seattle
2007, 2008, 2009; Liege 2007; Auckland 2008)
- Taught in short courses topics related to clinical trials at University of Sydney
- Associate Editor for The American Statistician, The
Stata Journal; reviewer for
Biometrics, Journal of Statistical Software,
JASA, Statistics & Probability Letters, American
Journal of Epidemiology, Biometrical Journal,
Biostatistics, Journal of Statistical Planning and Inference, Journal of the Air & Waste Management
Association , Medical Decision Making,
Epidemiology, ANZ Journal of Statistics, JAMA,
Circulation, Biometrika, Epidemiology, ANZ
Journal of Public Health, Environmental Health Perspectives,
Annals of Applied Statistics, Statistics and Computing,
Computational Statistics and Data Analysis, Statistics in
Medicine
- external reviewer for the EPA, the Health Effects Institute, and the New Zealand Health Research Council.
- NIH study section panelist for conflict of interest reviews (2001)
for several ad hoc reviews, and for 'Cardiovascular effects of HIV'
(2008).
- member of review panel for the Howard Hughes Medical Institute
Predoctoral Fellowships (until the program ended).
- I am a member of the core development team for the free
R statistical system, a dialect of the S language used around the world for teaching and research.
- I have written GEE and survival analysis
packages for XLISP-Stat, and a survey analysis
package for R. All these have been used by people I have never met.
- Secretary/Treasurer of the ASA Section on
Statistical Graphics (2000-1)
- JSM 2010 Program Committee representative for the Section on
Statistical Computing.
- Organizer of DSC2005, an international workshop on directions in
statistical computing.
Publications
- New methodology (peer-reviewed journals)
- Lumley T. (1995) "Efficient execution of Stone's likelihood ratio tests for disease clustering" Computational Statistics and Data Analysis 20: 499--510
- Lumley T. (1996) "Generalized Estimating Equations for ordinal
data: a note on working correlation structures" Biometrics 52: 354--361
- Lumley T, Heagerty PJ, (1999) "Weighted Empirical Adaptive Variance Estimators for Correlated Data Regression" Journal of the Royal Statistical Society, Series B.61:459-477
- Heagerty PJ, Lumley T (2000) "Window subsampling of estimating functions with application to regression models" JASA 95:197-211.
- Heagerty PJ, Lumley T, Pepe MS. (2000) "Time-dependent ROC curves for censored survival data and a diagnostic marker" Biometrics56: 337-344
- Sutherland P, Rossini A, Lumley T, Lewin-Koh N, Dickerson J, Cox Z, Cook D. (2000) "ORCA: A visualisation toolkit for high-dimensional data" Journal of Computational and Graphical Statistics 9: 509-529
- Lumley T, Levy D (2000) "Bias in the case-crossover design: implications for studies of air pollution" Environmetrics 11: 689-704
- Lumley T, Sheppard L (2000) "Assessing seasonal confounding and model selection bias in air pollution epidemiology using positive and negative control analyses" Environmetrics11:705-717
- Lumley T, Heagerty PJ (2000) "Graphical Exploratory Analysis of Survival Data" Journal of Computational and Graphical Statistics 9: 738-749
- Levy D, Lumley T, Sheppard L, Kaufman J, Checkoway H. (2001) "Referent selection in case-crossover analyses of acute health effects of air pollution" Epidemiology 186-92
- Lumley T, Simes RJ, Gebski V, Hudson HM. (2001) "Combining
components of quality of life to increase precision and evaluate
trade-offs" Statistics in Medicine
20:3231--3249
- Lumley T (2002) "Network meta-analysis for indirect treatment
comparisons" Statistics in Medicine
21:
2313-2324
- Alonzo TA, Pepe MS, Lumley T. (2003)"Estimating disease prevalence in
two-phase studies." Biostatistics
4(2):313-26.
- Janes H, Sheppard L, Lumley T. (2004) "Overlap bias in the
case-crossover design, with application to air pollution exposures."
Statistics in Medicine Jan 30;24(2):285-300
- Cai T, Pepe MS, Zheng Y, Lumley T, Swords Jenny N. (2005) The
Sensitivity and Specificity of Markers for Event Times. Biostatistics
August 3
- French B, Lumley T, Monks SA, Rice KM, Hindorff LA, Reiner AP,
Psaty BM. (2006) Simple estimates of haplotype relative risks in
case-control data
Genetic Epidemiology
Published Online: 5 Jun 2006
- Larson, T., Covert, D., Kim, E., Schreuder, A. and Lumley, T. (2006)
Combining Size Distribution and Chemical Species Measurements into a
Single Multivariate Receptor Model of PM2.5 Journal of Geophysical
Research , 111, D10S09, doi:10.1029/2005JD006285.
- Lovasi GS, Moudon AV, Smith NL, Lumley T, Larson EB, Sohn DW,
Siscovick DS, Psaty BM. (2007) Evaluating options for measurement of
neighborhood
socioeconomic context: Evidence from a myocardial infarction case-control
study.
Health Place. 2007 Sep 21;
- Buzkova P,Lumley T (2007) Longitudinal data analysis for
generalized linear models with follow-up dependent on outcome-related
variables. Canadian J Stat. 35 (4) 485-500
- Buzkova P, Lumley T (2008) Semiparametric Loglinear Regression
for Longitudinal Measurements Subject to Irregular, Biased Follow-up.
JSPI. 138 (8) 2450-2461
- Chung H, Lumley T. (2008) Graphical exploration of
network meta-analysis data: the use of multidimensional scaling.
Clinical Trials. 2008;5(4):301-7.
- Buzkova P, Lumley T (2008) Semiparametric modeling of repeated
measurements under outcome-dependent follow-up. Stat
Med 2008 Nov 26. [Epub ahead of print]
- Breslow N, Lumley T, Ballantyne CM, Chambless LE, Kulick M. (2009)
Improved Horvitz-Thompson estimation of model parameters from two-phase
stratified samples: applications in epidemiology. Statistics in
Biosciences. doi 10.1007/s12561-009-9001-6
- Methodology: technology transfer (peer-reviewed journals)
- Lumley T (1996) "XLISP-Stat tools for building Generalised Estimating
Equation models" Journal of Statistical Software. 1; 3: 1-20
- Lumley T, (1998) "Survival Analysis in XLISP-Stat: a semi-literate program", Journal of Statistical Software.3:2;1-90
- Lumley T, Sutherland P, Rossini A, Lewin-Koh N, Cook D,Cox Z. (2002)
"Visualising high-dimensional data in time and space: ideas from
the Orca project." Chemometrics and Intelligent Laboratory
Systems 60: 189-95
- Lumley T, Diehr P, Emerson S, Chen L. (2002) "The importance of the
Normality Assumption in Large Public Health Data Sets" Annual Review
of Public Health
23:151-169
- Lumley T. (2004) "Analysis of complex survey samples" Journal of
Statistical Software 9(8)
-
Sheppard L, Slaughter JC, Schildcrout J, Liu LJ, Lumley T. (2004) "Exposure and measurement contributions to estimates of acute air pollution effects." J Expo Anal Environ Epidemiol. 2004
- Janes H, Sheppard L, Lumley T. (2005) Case-Crossover Analyses of Air
Pollution Exposure Data: Referent Selection Strategies and Their
Implications for Bias. Epidemiology
2005 Nov;16(6):717-726.
- Kooperberg C, Bis JC, Marciante KD, Heckbert SR, Lumley T, Psaty
BM. (2006) Logic Regression for Analysis of the Association between
Genetic Variation in the Renin-Angiotensin System and Myocardial
Infarction or Stroke.
Am J Epidemiol. 2006 Nov 2;
- Lumley T, Rice KM, Psaty BM.Carryover effects after cessation of drug
treatment: trophies or dreams?
Am J Hypertens. 2008
Jan;21(1):14-6."
- Sarnat JA, Wilson WE, Strand M, Brook J, Wyzga R, Lumley T. Exposure
assessment and related errors in air pollution epidemiologic
studies. J Expo Sci Environ Epidemiol. 2007 Dec;17 Suppl 2:S75-82.
- Bateson TF, Coull BA, Hubbell B, Ito K, Jerrett M, Lumley T, Thomas
D, Vedal S, Ross M. Issues involved in interpretation of epidemiologic
analyses--statistical modeling. J Expo Sci Environ Epidemiol. 2007 Dec;17
Suppl 2:S90-6.
- Breslow NE, Lumley T, Ballantyne CM, Chambless LE, Kulich M. (2009) Using the Whole Cohort in the Analysis of
Case-Cohort Data. Am J Epidemiol. 2009 Apr 8. [Epub ahead of print]
- Applications (peer-reviewed journals)
- Lumley T. (1992) "Coeducation and factors affecting the choice of university courses." Australian Educational Researcher 19;2 51--60
- Jorgensen JO, Gillies RB, Hunt DR, Caplehorn JRM, Lumley T (1995) "A simple and
effective way to reduce postoperative pain after laparoscopic cholecystectomy."
Australian and New Zealand Journal of Surgery 65: 466--469
- Sullivan J, Learmont J, Lumley T, Geczy A, Cook L. (1995) "A direct
association between HIV and AIDS in blood transfusion donors and recipients" AIDS Research and Human Retroviruses 11: 1147--1148
- Cozzi P.J., Lynch W.J., Robson N, Vonthethoff T, Lumley T, Morris D.L. (1996) "In vitro and in vivo assessment of urethral warming catheters for transperineal cryoablation of prostate carcinoma" British Journal of Urology 78: 589--595
- Nakagomi A, Celemajer D.S., Lumley T, Freedman S.B. (1996) "Angiographic Severity of Coronary Narrowing is a Surrogate Marker for the Extent of Coronary Atherosclerosis". American Journal of Cardiology 78: 516--519.
- Beller E, Tattersall M, Lumley T, et al. (1997) "Improved
quality of life with megestrol acetate in patients
with endocrine-insensitive advanced cancer: a randomised
placebo-controlled trial". Annals of Oncology 8: 277-283
- Mackerras D, Lumley T. (1997) ``First- and second-year effects in trials of calcium supplementation on the loss of bone density in post-menopausal women.'' Bone 21; 6:527--533
- Cannavo M., Fairbrother G., Owen D., Lumley T. (1998) "A comparison of dressings in management of surgical abdominal wounds." Journal of Wound Care 7: 57-62
- Caplehorn J., Lumley T., Irwig L., Saunders J. (1998) ``Changing
attitudes and beliefs of staff working in methadone maintenance
programs.'' Australian and New Zealand Journal of Public Health
22;4: 505--508
- Caplehorn JR, Lumley T, Irwig L (1998) "Staff attitudes and retention of patients in methadone maintenance programs." Drug and Alcohol Dependence 52:57-61
- Martin AJ, Glasziou PP, Simes RJ, Lumley T. (1998) "Predicting patients' utilities from quality of life items: an improved scoring system for the UBQ-H." Quality of Life Research 7;8:703-11
- Veenstra DL,Saint S, Saha S;
Lumley T, Sullivan S. (1999)
"Efficacy of Antiseptic Impregnated Central Venous Catheters in
Preventing Nosocomial Infections: A Meta-analysis" JAMA 281:261-267
- Jarvik JG, Robertson WD, Wessbecher F, Reger K, Solomon C, Whitten T,
Lumley T, Deyo RA. (2000) "Variation in the Quality of Lumbar Spine
Magnetic Resonance Imaging in Washington State" Radiology 215:
483--90
- Martin AJ, Glasziou PP, Simes RJ, Lumley T. (2000) "A comparison of standard gamble, time trade-off and adjusted time trade-off scores" International Journal of Technology Assessment in Health Care 16:137-47
- Yu O, Sheppard L, Lumley T, Koenig JQ, Shapiro GG (2000) "Effects of ambient air pollution on symptoms of asthma in Seattle-area children" Environmental Health Perspectives 108:1209-1214.
- Levy, D., Sheppard, L., Checkoway, H., Kaufman, J., Lumley, T.,
Koenig, J., Koepsell, T. and Siscovick, D (2001). "A
case-crossover analysis of particulate matter air pollution and
out-of-hospital primary cardiac arrest",Epidemiology 12:193-9
- Psaty BM, Furberg CD, Kuller LH, Cushman M, Savage PJ, Levine D,
O'Leary DH, Bryan N, Anderson M, Lumley T (2001) "The association between
level of blood pressure and the risk of cardiovascular disease: the
Cardiovascular Health Study" Archives of Internal Medicine
161:1183-92
- Lumley T, Kronmal D, Cushman M, Manolio TA, Goldstein S. (2002)
Predicting stroke in the elderly: validation and web-based application.
Journal of Clinical Epidemiology
55(2)
129-36.
- Goswami E, Larson T, Lumley T, Liu L-JS "Spatial Characteristics of
Fine Particulate Matter: Identifying Representative Monitoring Locations
in Seattle, Washington" Journal of the Air & Waste Management
Association 52: 324-333
- Psaty BM, Smith NL, Heckbert SR, Vos HL, Lemaitre RN, Reiner
AP, Siscovick DS, Bis J, Lumley T, Longstreth WT, Rosendaal FR.
(2002) "Diuretic therapy, the alpha-adducin variant, and the risk
of myocardial infarction or stroke in subjects with treated hypertension"
JAMA
287:1680-1689
- Holt VL, Kernic MA, Lumley T, Wolf ME, Rivara FP. (2002)
"Civil protection orders and risk of subsequent police-reported violence."
JAMA. 2002 ;288(5):589-94.
- Psaty BM, Manolio TA, Smith NL, Heckbert SR, Gottdiener JS, Burke GL,
Weissfeld J, Enright P, Lumley T, Powe N, Furberg CD. (2002) "Time trends
in high blood pressure control and the use of antihypertensive medications
in older adults: the cardiovascular health study." Arch
Intern Med 2002 Nov 11;162(20):2325-32.
- Villaveces A, Cummings P, Koepsell TD, Rivara FP, Lumley T, Moffat J.
(2003) "Association of Alcohol-related Laws with Deaths due to Motor
Vehicle
and Motorcycle Crashes in the United States, 1980-1997."
Am J Epidemiol.
157(2):131-40.
- Reiner AP, Heckbert SH, Vos HL, Ariens RA, Lemaitre RN, Smith NL,
Lumley T, Rea TD, Hindorff LA, Schellenbaum GD, Rosendaal FR, Siscovick
DS, Psaty BM. (2002) "Genetic variants of coagulation factor XIII,
post-menopausal estrogen therapy, and risk of non-fatal myocardial
infarction."
Blood,
2002 Nov 27 (e-publication ahead of print version).
- Psaty BM, Lumley T, Furberg CD, Schellenbaum G, Pahor M, Alderman MH,
Weiss NS (2003) "Health outcomes associated with various antihypertensive
therapies used as first-line agents. A network meta-analysis."
JAMA
289:2534-2544
- Smith NL, Psaty BM, Rutan GH, Lumley T, Yanez D, Chaves PH,
Kronmal RA. (2003) "The Association Between Time Since Last Meal and Blood Pressure in
Older Adults: The Cardiovascular Health Study." J
Am Geriatr Soc 2003 Jun;51(6):824-828
- Liu LJ, Box M, Kalman D, Kaufman J, Koenig J, Larson T, Lumley T,
Sheppard L, Wallace L. (2003) "Exposure Assessment of Particulate Matter
for Susceptible Populations in Seattle." Environmental Health
Perspectives
111(7):909-918.
-
Slaughter JC, Lumley T, Sheppard L, Koenig JQ, Shapiro GG. (2003)
Effects of ambient air pollution on symptom severity and medication
use in children with asthma. Ann Allergy Asthma
Immunol.
91(4):346-53.
- Koenig JQ, Jansen K, Mar TF, Lumley T, Kaufman J, Trenga CA, Sullivan
J, Liu LJ, Shapiro GG, Larson TV. (2003) Measurement of offline exhaled
nitric oxide in a study of community exposure to air pollution.
Environmental Health Perspectives
111(13):1625-9
-
Bis JC, Smith NL, Psaty BM, Heckbert SR, Edwards KL, Lemaitre RN, Lumley
T, Rosendaal FR. Angiotensinogen Met235Thr polymorphism,
Angiotensin-Converting Enzyme inhibitor therapy, and the risk of
nonfatal stroke or myocardial infarction in
hypertensive patients.
Am J Hypertens 2003; 16: 1011-1017
- Psaty BM, Lumley T, Furberg CD. Meta-analysis of health outcomes of
chlorthalidone-based vs nonchlorthalidone-based low-dose diuretic
therapies. JAMA.
2004 Jul 7;292(1):43-4.
-
Psaty BM, Anderson M, Kronmal RA, Tracy RP, Orchard T, Fried LP, Lumley T,
Robbins J, Burke G, Newman AB, Furberg CD. The association between lipid
levels and the risks of incident myocardial infarction, stroke, and total
mortality: the cardiovascular health study. J
Am Geriatr Soc. 2004 Oct;52(10):1639-47.
- Schellenbaum GD, Rea TD, Heckbert SR, Smith NL, Lumley T, Roger VL,
Kitzman DW, Taylor HA, Levy D, Psaty BM.
Survival associated with two sets of diagnostic criteria for congestive
heart failure.
Am J Epidemiol. 2004 Oct 1;160(7):628-35.
- Smith NL, Chan JD, Rea TD, Wiggins KL, Gottdiener JS, Lumley T, Psaty
BM. Time trends in the use of beta-blockers and other pharmacotherapies in
older adults with congestive heart failure.
Am
Heart J. 2004 Oct;148(4):710-7.
- Smith NL, Heckbert SR, Lemaitre RN, Reiner AP, Lumley T, Weiss NS,
Larson EB, Rosendaal FR, Psaty BM. Esterified Estrogens and Conjugated
Equine Estrogens and the Risk of Venous Thrombosis.
JAMA. 2004;292:1581-1587.
- van der Palen J, Rea TD, Manolio TA, Lumley T, Newman AB, Tracy RP, Enright PL, Psaty BM. (2004) Respiratory muscle strength and the risk of incident cardiovascular events. Thorax. 2004 Dec;59(12):1063-7.
- Hindorff LA, Heckbert SR, Psaty BM, Lumley T, Siscovick DS,
Herrington DM,
Edwards KL, Tracy RP. beta(2)-Adrenergic receptor polymorphisms and
determinants of cardiovascular risk: the Cardiovascular Health Study.
Am J
Hypertens. 2005 Mar;18(3):392-7.
- Koenig JQ, Mar TF, Allen RW, Jansen K, Lumley T, Sullivan JH, Trenga
CA, Larson T, Liu LJ.
Pulmonary effects of indoor- and outdoor-generated particles in children
with asthma. Environ
Health Perspect. 2005 Apr;113(4):499-503.
- Reiner AP, Diehr P, Browner WS, Humphries SE, Jenny NS, Cushman M, Tracy RP, Walston J, Lumley T, Newman AB, Kuller LH, Psaty BM. Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study. Atherosclerosis. 2005 Jul;181(1):175-83.
- Schellenbaum GD, Heckbert SR, Smith NL, Rea TD, Lumley T, Kitzman DW, Roger VL, Taylor HA, Psaty BM. Congestive Heart Failure Incidence and Prognosis: Case Identification Using Central Adjudication Versus Hospital Discharge Diagnoses. Ann Epidemiol. 2005 Jun 15; [Epub ahead of print]
- Chan JD, Rea TD, Smith NL, Siscovick D, Heckbert SR, Lumley T, Chaves
P, Furberg CD, Kuller L, Psaty BM. Association of beta-blocker use with
mortality among patients with congestive heart failure in the
Cardiovascular Health Study (CHS). Am Heart J. 2005 Sep;150(3):464-70.
- Schellenbaum GD, Smith NL, Heckbert SR, Lumley T, Rea TD, Furberg CD, Lyles MF, Psaty BM. Weight loss, muscle strength, and Angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension.
J Am Geriatr Soc. 2005 Nov;53(11):1996-2000.
- Mar TF, Jansen K, Shepherd K, Lumley T, Larson TV, Koenig JQ. Exhaled nitric oxide in children with asthma and short-term PM2.5 exposure in Seattle.
Environ Health Perspect. 2005 Dec;113(12):1791-4.
- Karr C, Lumley T, Shepherd K, Davis R, Larson T, Ritz B, Kaufman
J. A case-crossover study of wintertime ambient air pollution and infant
bronchiolitis.
Environ Health Perspect. 2006 Feb;114(2):277-81.
- Hindorff LA, Psaty BM, Carlson CS, Heckbert SR, Lumley T, Smith
NL, Lemaitre RN, Rieder MJ, Nickerson DA, Reiner AP. Common Genetic
Variation in the Prothrombin Gene, Hormone Therapy, and Incident Nonfatal
Myocardial Infarction in Postmenopausal Women.
Am J Epidemiol.
2006 Feb 8;
[Epub ahead of print]
-
Lemaitre RN, Weiss NS, Smith NL, Psaty BM, Lumley T, Larson EB, Heckbert
SR. Esterified estrogen and conjugated equine estrogen and the risk of
incident myocardial infarction and stroke.
Arch Intern Med. 2006 Feb 27;166(4):399-404.
- Sotoodehnia N, Siscovick DS, Vatta M, Psaty BM, Tracy RP, Towbin JA,
Lemaitre RN, Rea TD, Durda JP, Chang JM, Lumley TS, Kuller LH, Burke GL,
Heckbert SR. Beta2-adrenergic receptor genetic variants and risk of sudden
cardiac death.
Circulation. 2006 Apr 18;113(15):1842-8.
- Schildcrout JS, Sheppard L, Lumley T, Slaughter JC, Koenig JQ,
Shapiro GG.(2006) Ambient air pollution and asthma exacerbations in
children: an eight-city analysis.
Am J Epidemiol. 2006
Sep 15;164(6):505-17.
- Smith NL, Heckbert SR, Doggen CJ, Lemaitre RN, Reiner AP, Lumley T,
Meijers JC, Psaty BM, Rosendaal FR (2006) The differential association of
conjugated equine estrogen and esterified estrogen with activated protein
C resistance in postmenopausal women.
J Thromb Haemost. 2006
Aug;4(8):1701-6.
- Smith NL, Barzilay JI, Kronmal R, Lumley T, Enquobahrie D, Psaty
BM.New-onset diabetes and risk of all-cause and cardiovascular mortality:
the Cardiovascular Health Study.
Diabetes Care.
2006 Sep;29(9):2012-7.
- Smith NL, Heckbert SR, Lemaitre RN, Reiner AP, Lumley T, Rosendaal
FR, Psaty BM.(2006) Conjugated equine estrogen, esterified estrogen,
prothrombotic variants, and the risk of venous thrombosis in
postmenopausal women.
Arterioscler Thromb Vasc Biol.
2006 Dec;26(12):2807-12
- Dublin S, French B, Glazer NL, Wiggins KL, Lumley T, Psaty BM,
Smith NL, Heckbert SR.Risk of new-onset atrial fibrillation in relation to
body mass index.
Arch Intern Med.
2006 Nov 27;166(21):2322-8.
- Karr C, Lumley T, Schreuder A, Davis R, Larson T, Ritz B, Kaufman J.
Effects of Subchronic and Chronic Exposure to Ambient Air Pollutants on
Infant Bronchiolitis.
Am J Epidemiol.
2006 Dec 8;
-
Smith NL, Hindorff LA, Heckbert SR, Lemaitre RN, Marciante KD, Rice K,
Lumley T, Bis JC, Wiggins KL, Rosendaal FR, Psaty BM. Association
of genetic variations with nonfatal venous thrombosis in postmenopausal
women.
JAMA.
2007 Feb 7;297(5):489-98.
- Mukamal KJ, Lumley T, Luepker RV, Lapin P, Mittleman MA, McBean AM,
Crum RM, Siscovick DS.Alcohol consumption in older adults and Medicare
costs.
Health Care Financ Rev. 2006 Spring;27(3):49-61.
-
Lovasi GS, Lemaitre RN, Siscovick DS, Dublin S, Bis JC, Lumley T, Heckbert
SR, Smith NL, Psaty BM.Amount of leisure-time physical activity and risk
of nonfatal myocardial infarction.
Ann Epidemiol. 2007 Jun;17(6):410-6
- Marciante KD, Bis JC, Rieder MJ, Reiner AP, Lumley T, Monks SA,
Kooperberg C, Carlson C, Heckbert SR, Psaty BM. Renin-Angiotensin system
haplotypes and the risk of myocardial infarction and stroke in
pharmacologically treated hypertensive patients.
Am J Epidemiol. 2007 Jul 1;166(1):19-27.
- Smith NL, Bis JC, Biagiotti S, Rice K, Lumley T, Kooperberg C,
Wiggins KL, Heckbert SR, Psaty BM (2007) Variation in 24 Hemostatic Genes
and Associations with Non-fatal Myocardial Infarction and Ischemic Stroke.
- Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR,
Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP,
Ellis SG, Tracy RP, Devlin JJ, Psaty BM. Association of Gene Variants With
Incident Myocardial Infarction in the Cardiovascular Health Study.
Arterioscler Thromb Vasc Biol. 2007 Nov 1;
- Bis JC, Heckbert SR, Smith NL, Reiner AP, Rice K, Lumley T, Hindorff
LA, Marciante KD, Enquobahrie DA, Monks SA, Psaty BM. Variation in
inflammation-related genes and risk of incident nonfatal myocardial
infarction or ischemic stroke. Atherosclerosis.
2007 Nov 2;
- Chubak J, Buist DS, Boudreau DM, Rossing MA, Lumley T, Weiss NS.
Breast cancer recurrence risk in relation to antidepressant use after
diagnosis.
Breast Cancer Res Treat. 2007 Dec 6;
- van Stralen KJ, Doggen CJ, Lumley T, Cushman M, Folsom AR, Psaty BM,
Siscovick D, Rosendaal FR, Heckbert SR.The Relationship Between Exercise
and Risk of Venous Thrombosis in Elderly People. J
Am Geriatr Soc. 2008 Jan 4;
- Zheng AY, Lawhorn JK, Lumley T, Freeman S. Application of Bloom's
Taxonomy Debunks the "MCAT Myth", Science
Vol.
319. no. 5862, pp. 414 - 415
- Lemaitre RN, Heckbert SR, Sotoodehnia N, Bis JC, Smith NL, Marciante
KD, Hindorff LA, Lange LA, Lumley TS, Rice KM, Wiggins KL, Psaty BM.
beta1- and beta2-Adrenergic Receptor Gene Variation, beta-Blocker Use and
Risk of Myocardial Infarction and Stroke. Am J Hypertens. 2008
Mar;21(3):290-6. Epub 2008 Jan 24.
- Lovasi GS, Moudon AV, Pearson AL, Hurvitz PM, Larson EB, Siscovick
DS, Berke EM, Lumley T, Psaty BM. Using built environment characteristics
to predict walking for exercise.Int J Health Geogr. 2008 Feb 29;7(1):10
- Marciante KD, Totah RA, Heckbert SR, Smith NL, Lemaitre RN, Lumley T,
Rice KM, Hindorff LA, Bis JC, Hartman B, Psaty BM. Common variation in
cytochrome P450 epoxygenase genes and the risk of incident nonfatal
myocardial infarction and ischemic stroke. Pharmacogenet Genomics. 2008
Jun;18(6):535-543
- Enquobahrie DA, Smith NL, Bis JC, Carty CL, Rice KM, Lumley T,
Hindorff LA, Lemaitre RN, Williams MA, Siscovick DS, Heckbert SR, Psaty
BM. Cholesterol ester transfer protein, interleukin-8, peroxisome
proliferator activator receptor alpha, and toll-like receptor 4 genetic
variations and risk of incident nonfatal myocardial infarction and
ischemic stroke.
Am J Cardiol. 2008 Jun 15;101(12):1683-8.
- Hindorff LA, Lemaitre RN, Smith NL, Bis JC, Marciante KD, Rice KM,
Lumley T, Enquobahrie DA, Li G, Heckbert SR, Psaty BM.Common genetic
variation in six lipid-related and statin-related genes, statin use and
risk of incident nonfatal myocardial infarction and stroke. Pharmacogenet
Genomics. 2008 Aug;18(8):677-82.
- Thomas MC, Dublin S, Kaplan RC, Glazer NL, Lumley T, Longstreth WT
Jr, Smith NL, Psaty BM, Siscovick DS, Heckbert SR.Blood pressure control
and risk of incident atrial fibrillation.Am J Hypertens. 2008
Oct;21(10):1111-6
- Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT Jr, Lumley T, Rice K, Tracy RP, Devlin JJ,
Psaty BM.Gene Variants Associated With Ischemic Stroke. The Cardiovascular Health Study. Stroke. 2008 Nov 20. [Epub ahead of print]
- Wiggins KL, Smith NL, Glazer NL, Rosendaal FR, Heckbert SR, Psaty BM,
Rice KM, Lumley T. ABO genotype and risk of thrombotic events and
hemorrhagic stroke.J
Thromb Haemost. 2008 Nov 25. [Epub ahead of print]
- Hindorff LA, Burke W, Laberge AM, Rice KM, Lumley T, Leppig K,
Rosendaal FR, Larson EB, Psaty BM. Motivating factors for physician
ordering of factor V Leiden genetic tests. Arch
Intern Med. 2009 Jan 12;169(1):68-74.
- Lemaitre RN, Rice K, Marciante K, Bis JC, Lumley TS, Wiggins KL,
Smith NL, Heckbert SR, Psaty BM. Variation in eicosanoid genes, non-fatal
myocardial infarction and ischemic stroke.Atherosclerosis. 2008 Nov 1.
- van der Bom JG, Heckbert SR, Lumley T, Holmes CE, Cushman M, Folsom
AR,
Rosendaal FR, Psaty BM. Platelet count and the risk for thrombosis and
death in the elderly.J Thromb Haemost. 2008 Dec 20.
- Heckbert SR, Wiggins KL, Glazer NL, Dublin S, Psaty BM, Smith NL,
Longstreth Jr WT, Lumley T. Antihypertensive Treatment With ACE Inhibitors
or beta-Blockers and Risk of Incident Atrial Fibrillation in a General
Hypertensive Population. Am J Hypertens. 2009 Mar 5. [Epub ahead of print]
- Newton-Cheh C, Eijgelsheim M, Rice KM, de Bakker PI, Yin X, Estrada
K, Bis JC, Marciante K, Rivadeneira F, Noseworthy PA, Sotoodehnia N, Smith
NL, Rotter JI, Kors JA, Witteman JC, Hofman A, Heckbert SR, O'Donnell CJ,
Uitterlinden AG, Psaty BM, Lumley T, Larson MG, Stricker BH. Common
variants at ten loci influence QT interval duration in the QTGEN Study.
Nature Genetics 2009 Apr;41(4):399-406.
- Lemaitre RN, King IB, Sotoodehnia N, Rea TD, Raghunathan TE, Rice KM, Lumley TS, Knopp RH, Cobb LA, Copass MK,
Siscovick DS.Red blood cell membrane alpha-linolenic acid and the risk of sudden cardiac arrest. Metabolism. 2009
Apr;58(4):534-40.
- Ikram MA, Seshadri S, Bis JC, Fornage M, DeStefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den
Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F,
Kelly-Hayes M, Lopez OL, Coresh J, Hofman A, DeCarli C, Heckbert SR, Koudstaal PJ, Yang Q, Smith NL, Kase CS, Rice K,
Haritunians T, Roks G, de Kort PL, Taylor KD, de Lau LM, Oostra BA, Uitterlinden AG, Rotter JI, Boerwinkle E, Psaty
BM, Mosley TH, van Duijn CM, Breteler MM, Longstreth WT Jr, Wolf PA.Genomewide association studies of stroke. N Engl J
Med. 2009 Apr 23;360(17):1718-28.
- Daniel Levy, Georg B Ehret, Kenneth Rice, Germaine C Verwoert, Lenore
J Launer, Abbas Dehghan, Nicole L Glazer, Alanna C Morrison, Andrew D
Johnson, Thor Aspelund, Yurii Aulchenko, Thomas Lumley, Anna Köttgen,
Ramachandran S Vasan, Fernando Rivadeneira, Gudny Eiriksdottir, Xiuqing
Guo, Dan E Arking, Gary F Mitchell, Francesco U S Mattace-Raso, Albert V
Smith, Kent Taylor, Robert B Scharpf, Shih-Jen Hwang, Eric J G Sijbrands,
Joshua Bis, Tamara B Harris, Santhi K Ganesh, Christopher J O'Donnell,
Albert Hofman, Jerome I Rotter, Josef Coresh, Emelia J Benjamin, André G
Uitterlinden, Gerardo Heiss, Caroline S Fox, Jacqueline C M Witteman, Eric
Boerwinkle, Thomas J Wang, Vilmundur Gudnason, Martin G Larson, Aravinda
Chakravarti, Bruce M Psaty & Cornelia M van Duijn. Genome-wide
association study of blood pressure and hypertension. Nature Genetics
Published online: 10 May 2009. doi:10.1038/ng.384
- Anna Köttgen, Nicole L Glazer, Abbas Dehghan, Shih-Jen Hwang, Ronit
Katz, Man Li, Qiong Yang, Vilmundur Gudnason, Lenore J Launer, Tamara B
Harris, Albert V Smith, Dan E Arking, Brad C Astor, Eric Boerwinkle, Georg
B Ehret, Ingo Ruczinski, Robert B Scharpf, Yii-Der Ida Chen, Ian H de
Boer, Talin Haritunians, Thomas Lumley, Mark Sarnak, David Siscovick,
Emelia J Benjamin, Daniel Levy, Ashish Upadhyay, Yurii S Aulchenko, Albert
Hofman, Fernando Rivadeneira, André G Uitterlinden, Cornelia M van Duijn,
Daniel I Chasman, Guillaume Paré, Paul M Ridker, W H Linda Kao,
Jacqueline C Witteman, Josef Coresh, Michael G Shlipak & Caroline S Fox.
Multiple loci associated with indices of renal function and chronic kidney
disease. Nature Genetics. Published online: 10 May 2009.
doi:10.1038/ng.377
- Smith NL, Rice KM, Lumley T, Heckbert SR, Psaty BM. Discovering novel
risk factors for venous thrombosis: a candidate-gene approach. Thromb
Res. 2009;123 Suppl 4:S25-9
- Peer-reviewed
conference abstracts
- Lumley T (2005) Pre- and Post-processing to Improve ARIMA-based
Anomaly Detection.. 2005 Syndromic Surveillance Conference.
- Lober W, Drozd D, Lumley T, Sebestyen K, Painter I. An Open
Source Web Services Toolkit For Event Detection Algorithms. 2005 Syndromic
Surveillance Conference.
- Lumley T, Sebestyen K, Lober W, Painter I. An Open Source Environment
For The Statistical Evaluation Of Outbreak Detection Methods. Annual
Symposium of American Medical Informatics Association 2005.
- Invited
presentations and workshops
- "Generalised Estimating Equations for Ordinal Data", seminar series, Macquarie University Department of Statistics, August 1995
- "Statistical Bibliography: Past Historic, Present Imperfect, Future Conditional", Sydney International Statistics Congress June, 1996.
- "Marginal Regression models for weakly dependent data", seminar, Johns Hopkins School of Public Health, December 1997
- "Marginal regression models for weakly dependent data", seminar,
University of Auckland, Dept of Statistics, June 1998
- "Survival analysis with recurrent events", seminar, University of Sydney, Department of Public Health, July 1998
- Workshop on Distributed Statistical Computing, Vienna University of
Technology, March 1999
- Symposium on the case-crossover design. International Society for Environmental Epidemiology conference, Buffalo, August 2000
- "Visualising high dimensional data over time and space: ideas and tools
from the Orca project", 4th International Conference on Environmetrics and Chemometrics, Las Vegas, September 2000.
- Workshop on Distributed Statistical Computing, Vienna University of Technology, March 2001
- "Network meta-analysis for indirect treatment comparisons", Macquarie University Department of Statistics, September 2001.
- Australian Epidemiological Association, Sydney, September 2001: Workshop on survival analysis
- Biostatistical Collaboration of Australia, Sydney, September 2001: Workshop on multiple testing in clinical trials.
- "Regression modelling of sparsely correlated data", seminar, Texas A&M University, Department of Statistics, November 2001.
- "Network Meta-Analysis", seminar series, Iowa
State University Department of Statistics, September 2002.
- EPA workshop on GAM-related Statistical Issues in PM Epidemiology,
November 2002, North Carolina
- "Using source apportionment in health effects models", American
Association for Aerosol Research, Pittsburgh, April 2003.
- "Analysing networks of trials", seminar series, Columbia University
Department of Biostatistics, November 2003.
- "Generalised linear models for sparsely correlated data", University
of British Columbia, November 2003.
- "Stroke prediction: CHS experience", NHLBI workshop on stroke risk
assessment and primary prevention trials, January 2004.
- "Transitivity of two-sample tests", UW Department of Statistics,
January 2004
- "Survey analysis software in R", Census Bureau, June 2004
- Workshop on Statistical Science in Genome Biology, Banff
International Research Station, August 2004
- "Indirect comparisons of clinical trials". MRC Biostatistics Unit,
Cambridge University, September 2004.
- "R software for survey analysis", Department of Biostatistics,
Vanderbilt University, February 2005
- "When can more than two treatments be ranked?", Department of
Biostatistics, Vanderbilt University, February 2005
- "When the odds ratio is not the relative risk." Department of
Epidemiology, University of Washington, April 2005.
- "Combining results from networks of clinical trials." Department
of Epidemiology, University of Maastricht, June 2005.
- "Transitivity, coherence, and indirect comparisons". Department of
Statistics, University of Melbourne, February 2006.
- "Air pollution source apportionment: from characterization to
imputation" International Biometric Society (ENAR) Spring Meeting, Tampa,
March 2006
- EPA Workshop on Interpretation of Multi-pollutant Epidemiology
Studies, December 2006.
- "Transitivity of networks of comparisons", Department of Biostatistics, Harvard
University, January 2007.
- Workshop on computing in the undergraduate statistics curriculum.
MSRI, Berkeley, May 2007.
- Survey calibration estimators. 2007 WNAR/IMS meeting. UC Irvine, June
2007.
- "Source apportionment and health effects models" Joint Statistical
Meetings, Salt Lake City, 2007
- Discussant for "Model selection and robust inference" session. Joint
Statistical Meetings, Salt Lake City, 2007.
- "Survey calibration and semiparametric models", NIH/NIAID
Biostatistics Research Branch, September 2007
- "Calibration estimators and semiparametric models", Biostatistics
and Biomathematics seminars, Fred Hutchinson Cancer Research Center,
October 2007
- "Some less boring aspects of data from complex samples" MAPSS
colloqium, Stanford University, January 2008
- "Calibration estimators and semiparametric models". UW Center for
Statistics and the Social Sciences, February 2008.
- "Measurement error in clinical trials: some problems randomization
doesn't fix". Invited Translational Lecture, 48th Annual Conference on
Epidemiology and Prevention of Heart Disease, March, 2008.
- "Source apportionment and health effects models", The International
Environmetric Society conference, Kelowna, BC, June 2008
- "Open-source statistical software: how?, why?, where?", Washington
Statistical Society, June 2008
- "Robustness of efficiency in semiparametric models for incomplete
data" Dept of Statistics, University of Auckland, October 2008
- "Robustness of efficiency in semiparametric models for incomplete
data" Dept of Statistics, University of Waikato, October 2008.
- "Network meta-analysis and indirect comparisons" Dept of Preventive
and Social Medicine, Dunedin Medical School, November 2008
- "What does the Wilcoxon test mean?" Dept of Statistics, University of
Otago, November, 2008
- "Analysing complex samples with R" Official Statistics Seminar
Series, Statistics New Zealand, November 2008
- "Robustness of efficiency in semiparametric models for incomplete
data" Dept of Statistics, Victoria University of Wellington, November 2008
- "Network meta-analysis and indirect comparisons" Dept of Medical
Statistics and Genetics, Leiden University Medical Center, January 2009
- "Gene-environment interaction: lessions for semiparametric
efficiency" Dept of Statistics, University of G[h]ent, February 2009
- "What does the Wilcoxon test mean?" Epidemiology and Bioinformatics
seminar series, Leiden University Medical Center, February 2009
- "Case-crossover and other case-distribution designs" Biostatistics
seminar, University of Copenhagen, March 2009
- "Complex designs in epidemiology" One-day course, University of
Copenhagen, April 2009
- "Analyzing and reporting genome-wide association studies." Keynote lecture. World Federation of Neurology -
Neuroepidemiology Research Group, North American regional meeting, Seattle, May 2009.
- "Genome-wide association studies: data cleaning and data flow".
Institute for Translational Health Sciences, University of Washington, May
2009
- "Using the whole cohort in two-phase studies" Statistics
seminar series, RAND Corporation, June 2009.
- "Molecular epidemiology: how far will brute force and ignorance get
us?" Cohorts and consortia: from biotechnology to populations, Banff, June
2009.
- Invited conference tutorials
- "Analyses of two phase studies, with applications in epidemiology" Biometric Society WNAR 2008 (with Norm Breslow)
- "Advanced R Tutorial" International Association for Statistical Computing 2008 (with Peter Dalgaard, Duncan Murdoch, Simon
Urbanek)
- "Introduction to R and surveys", American Association for Public
Opinion Research annual conference, Hollywood, Fl, May 2009.
- "Two-phase stratified designs and analyses for epidemiology",
StatisticAlps, Ponte di Legno, (to occur September 2009)
- "R Day Camp", International Biometric Society (Australasian Region),
Auckland (to occur December 2009)
- Reviews, commentaries, letters, chapters, etc
- Lumley T, Keech A (1995) "Meta-meta-analysis with confidence."
[letter] Lancet 346: 576--577
- Lumley T (1995) "Statistical Interpretation of Study results" in
A Clinical Data Management Resource Manual, Australian and New Zealand Data Managers Association.
- Lumley T (1995) "Phase III Trials" in
A Clinical Data Management Resource Manual, Australian and New Zealand
Data Managers Association.
- Martin A, Lumley T, Simes RJ (1995) "Incorporating tradeoffs in quality of
life assessment" in Spilker B ed Quality of Life and Pharmacoeconomics in Clinical Trials[2nd edition] Lippincott-Raven, New York. 1995
- Lumley T (1999) Review of "Limit Theory for Mixing Dependent Random Variables" The Statistician 48: 147-8
- Lumley T (1999) Review of Stata 5.0 Statistics & Computing
- Lumley T (in press) Review of "Kendall's Library of Statistics. Volume 2A: Classical Inference & the Linear Model" Statistics in Medicine
- Sheppard L, Lumley T (2000) Discussion of: Domenci F, Samet J, Zeger S (2000) "Combining evidence on air pollution and daily mortality from the 20 largest US cities: a hierarchical modelling strategy" JRSS Series A 163:284-302
- Lumley T, Heagerty P, Pepe MS (2001) Response to: Crouchley R, Davies RB "A comparison of population average and random-effect models for the analysis of longitudinal count data with base-line information". JRSS Series A164: 209-210.
- Lumley T (2001) Review of "Environmental Statistics With S-PLUS" Technometrics 43: 11
- Rossini AJ, Lumley T (2002) "Beowulfs meet Statistics: An
Introduction to Cluster Supercomputers" Chance 15 (1)
- Lumley T, Rossini AJ (2002) "Database linkage, privacy, and medical research" Chance 15 (3).
- Lumley T, Rossini AJ (2002) "Something in the air?" Chance 15 (4)
- Lumley T, Sheppard L. (2003) "Time series analyses of air
pollution and health: straining at gnats and swallowing camels?"
Epidemiology. 2003 Jan;14(1):13-4
- Lumley T, Rossini AJ (2004) "Building a better spam-trap", Chance
16 (1)
- Lumley T (2004) "Sustainable sources of randomness", Chance 16 (2)
- van Belle G, Fisher LD, Heagerty PJ, Lumley T (2004)
Biostatistics: A Methodology for the Health Sciences (2nd
edition) New York: Wiley. (web
page)
- Janes H, Sheppard L, Lumley T.Comment on "Do subject characteristics modify the effects of particulate air pollution on daily mortality among the elderly?" J Occup Environ Med. 2005 Jun;47(6):543
- Rice K, Kronmal R, Lumley T.Analytic errors undermine conclusions of
cardiovascular study. [letter]
Arch Intern Med. 2006 Sep 18;166(16):1787.
- Lumley T, Janes H, Sheppard L. Correspondence: Cox Models for
Ecologic TimeSeries Data?
Environ Health Perspect. 2006 Dec;114(12):A690-1.
- Psaty BM, Lumley T (2008) Surrogate end points and FDA approval: a
tale of 2 lipid-altering drugs. JAMA. 2008 Mar 26;299(12):1474-6.