CURRICULUM VITAE

CURRICULUM VITAE

NAME: THOMAS G. EBREY

BORN: August 21, 1941

ADDRESS: Depts. of Botany and Zoology

Box 351330

University of Washington

Seattle, WA 98195

FAX: 206-543-3262

email: tebrey@u.washington.edu

EDUCATION:

1963 B.S. University of Oklahoma (Physics)

1968 Ph.D. University of Chicago (Physics)

PROFESSIONAL EXPERIENCE:

2000— Research Professor of Botany and Zoology, University of Washington, Seattle WA

1978—99 Professor of Biophysics, Department of Cell and Structural Biology, and Dept of Physiology University of Illinois, Urbana, IL

1990—91 Visiting Professor, Kyoto University, Kyoto, Japan

1983—84 Visiting Professor, Princeton University, Princeton, NJ

1978 Visiting Professor, Kyoto University, Kyoto Japan (summer)

1973—78 Associate Professor, Department of Physiology and Biophysics, University of Illinois, Urbana, IL Chairman, Biophysics Division

1971—72 Fellow, Kyoto University, Kyoto, Japan

1968—73 Assistant Professor, Department of Biological Sciences, Columbia University

1967—68 NIH Postdoctoral Fellow, Cornell University, Ithaca, NY

AWARDS AND HONORS:

1965—67 NIH Predoctoral Fellow, University of Chicago, Physics Department

1967—68 NIH Postdoctoral Fellow, Cornell University

1971—72 US—Japan Cooperative Science Program Fellow, Kyoto University, Kyoto, Japan

1975 NATO Senior Fellowship, Keio University, Tokyo, Japan

1975—80 NIH Research Career Development Award

1978 NIH US—Japan Exchange Program Fellow

1980 CSCPRC Fellowship for Research in China Program

1982 Visiting Scholar, Institute of Biophysics, Peking; Department of Biophysics, Kyoto University

1988 Fellow, AAAS

1988—89 Beckman Scholar, University of Illinois

1990—91 NSF US—Japan Cooperative Science Fellow, Kyoto University

RESEARCH SUPPORT

Current Research Support

Principal Investigator

NIH EY01323	"Studies on the Mechanisms of Visual Excitation"	9/99-9/03	$131,300/yr
NIH RO1 GM 52023	"Molecular Mechanisms Controlling Bacteriorhodopsin"	2/99-1/03	$164,090/yr (direct)

Planned Applications

New Application to NIH, Vibrational Spectroscopy of the visual Cascade

Past Research Support (External)

Principal Investigator or Equivalent

NIH R01 EY00433	Studies on the Mechanism of Visual Excitation	2/69-9/72	$45,612
NIH R01 EY00433	Studies on the Mechanism of Visual Excitation	8/72-8/73	$32,601
NIH R01 EY01323	Studies on the Mechanism of Visual Excitation	8/73-6/75	$68,221
NIH R01 EY01323	Studies on the Mechanism of Visual Excitation	6/75-6/80	$211,800
NIH K04 EY00025	Research Career Development Award	8/75-7/80	$125,000
NIH T32 EY07005	Physiology and Biochemistry of Vision Natl Research Service Award	7/75-7/80	$296,300
NATO	Senior Fellowship at Keio Univ.	6/75-8/75	$4,500
NSF 5-S-246	U.S.-Japan Seminar on Visual Pigments	8/75 ca.	ca/ $14,000
NSF PCM 76-82764	Light Energy Transduction in the Purple Membrane of Halobacterium halobium	8/77-8/79	$60,000
NIH R01 EY 01323	Studies on the Mechanism of Visual Excitation	9/80-9/85	$468,367
NIH T32 EY07005	Physiology and Biochemistry of Vision Natl Research Service Award	7/80-7/85	$428,200
NSF	U.S.-Japan Joint Seminar on The Purple Membrane of Halobacteria	5/80	ca/ $16,200
NSF PCM 79-11772	Light Energy Transduction in the Purple Membrane of Halobacterium halobium	8/79-8/82	$120,000
NIH subEY03142	subcontract from CCNY of Resonance Raman Study of Rhodopsin and Related Pigments	7/79-6/82	$37,798
NSF DMB 8201924	Light Energy Transduction in the Purple Membrane of Halobacterium halobium	8/82-8/85	$165,000
DOE ER12087	Mechanism of Proton Pumping in Bacteriorhodopsin	8/82-8/85	$155,421
NIH subEY03142	subcontract from CCNY of Resonance Raman Studies of Rhodopsin and related pigments	7/82-6/87	$76,380
NSF INT-8311815	U.S.-Japan Coop Research, Molecular Mechanism of Phototransduction in an Invertebrate Retina	6/84-5/86	$17,050
NIH EY01323	Studies on the Mechanism of Visual Excitation	9/85-9/90	$573,211
NSF DMB 85-15339	Light Energy Transduction in the Purple Membrane of Halobacterium halobium	1/86-12/89	$240,000
DOE ER 12087	Mechanism of Proton Pumping in Bacteriorhodopsin	7/85-7/88	$165,400
NIH	NEI Short Term Exchange Visit to Japan	5/88-7/88	$6,800
NSF REU	Res. Exp. Undergrad. Suppl. to DMB-85-15339	6/87-8/87	$3,887
DOE ER13948	Mechanism of Proton Pumping in Bacteriorhodopsin	7/88-2/92	$238,500
NSF INT-8922235	Long Term Research Visit: Photochemistry of Bacteriorhodopsin	9/90-9/91	$45,391
NSF DMB 88-15824	Light Energy Transduction in the Purple Membrane of Halobacterium halobium	3/89-2/92	$270,000
NIH subEY03142	Subcontract from CCNY of Resonance Raman Study of Rhodopsin and Related Pigments	7/87-6/92
NRC	NAS Soviet Exchange Program	1/93-6/93	$10,000
DOE FG02 88ER12948	Molecular Mechanisms Controlling Proton Pumping by Bacteriohodopsin	1/92-12/94	$293,000
NIH EY01323	Studies on the Mechanism of Visual Excitation	9/90-9/95	$124,643 /yr
NIH 5 T32 GM07283	Cellular and Molecular Biology Training Grant	7/96-6/01	$416,369 /yr
NIH RO1 GM 52023	Molecular Mechanisms Controlling Bacteriohodopsin	2/95-1/99	$80,000 /yr
NIH EY01323	Studies on the Mechanism of visual Excitation	9/95-9/99	$126,600 /yr
NIH RO1 GM 52023	Molecular Mechanisms Controlling Bacteriorhodopsin	2/99-1/03	$164,090 /yr
NIH 2 RO1 EYO-1323	Studies on the Mechanism of Visual Excitation	9/99-9/03	$131,467 /yr

PROFESSIONAL ACTIVITIES
Invited Plenary Lectures at National and International Meetings

Aug. 1972	Bochum, Germany	Biochemistry and Physiology of Visual Pigments
June 1973	Bethesda, MD	National Eye Institute: Rhodopsin, Its Chemistry and Function
Aug. 1975	Urbana, IL	US-Japan Conference on Visual Pigments
Oct. 1976	Julich, Germany	EMBO Workshop: Transduction Mechanisms of Photoreceptors
Dec. 1976	Bethesda, MD	Visual Pigments; Special Meeting at NIH in Honor of Professor T. Yoshizawa
Sept. 1978	Kyoto, Japan	Sixth International Biophysics Congress
May 1980	Kyoto, Japan	US-Japan Conference on Bacteriorhodopsin
Sept. 1980	Szegad, Hungary	ICRO-Light Energy Transduction by Bacteriorhodopsin
June 1981	Naples, Italy	EMBO Workshop on Halophilic Microorganisms
1981	Williamsburg,VA	American Society for Photobiology, Symp. on Visual Transduction
1982	Charleston, SC	Assoc. for Research in Vision and Ophthamology
June 1983	Crans, Switzerland	International Conference on Transduction in Membranes
Aug. 1983	Washington, DC	American Chemical Society Annual Meeting, Symposium on Bacteriorhodopsin
Jan. 1984	Honolulu, HA	US-Japan Conference on Visual Excitation
May 1984	Washington, DC	NAS Conference on Biosensors
Nov. 1984	Paris, France	UCLAF Conference on Vision
Nov. 1986	Urbana, IL	Biophysical Studies of Retinal Proteins
Feb. 1988	Phoenix, AZ	Biophysical Society Meeting; Symposium on Rhodopsin
May 1988	Kyoto, Japan	Third International Conference on Retinal Proteins
July 1990	Santa Cruz, CA	Fourth International Conference on Retinal Proteins
Nov. 1990		Molecular Electronics Tract of 12th IEEE Engineering in Medicine and Biology Society
Jan. 1992	Honolulu, HI	US-Japan Conference on Physical Studies of Retinal Pigments
June 1992	Paris, France	International Conference on Retinal Proteins
June 1995	Washington, DC	American Society for Photobiology
Nov. 1995	Nagoya, Japan	Nagoya University Symposium, Bacterial Rhodopsins
Nov. 1995	Urbana, IL	Computational/Experimental Approaches to Structural Biology
June 1996	Yaakov, Israel	Sixth International Conference on Retinal Proteins
Sep. 1996	Vienna, Austria	International Congress on Photobiology
Mar. 1997	Kyoto, Japan	US-Japan Symposium on Information and Energy Transduction by Retinal Proteins
June 1998	Awaji, Japan	Seventh International Conference on Retinal Proteins
Feb. 2000	Ventura, CA	Gordon Conference on Protons and Membrane Reactions
Sept. 2000	Szeged, Hungary	Eighth International Conference on Retinal Proteins
July 2001	Chicago, IL	American Society on Photobiology
Aug. 2001	Kyoto, Japan	Fourth International Conference on Biological Physics

Conferences Organized

1975	Urbana, IL	Co-organizer NSF US-Japan Conference on Structure and Function of Visual Pigments
1980	Kyoto, Japan	Co-organizer NSF US-Japan Conference on Light Energy Transduction in Halobacterium halobium
1986	Urbana, IL	Co-organizer Laura Eisenstein Memorial Meeting on Biophysical Studies of Retinal Proteins
		Member, Organizing Committee, Beckman Symposia on Protein Structure:
1992		Receptor Proteins: Structure, Function, and Modeling
1993		Protein Structure and Function
1994		Protein Structure and Design
1996		Beyond Protein Structure
2000	San Francisco, CA	Phototransduction. International Congress of Photobiology
2002	Seattle, WA	Chair, 10^th International Conference on Retinal Proteins

Editorial Boards

Guest Editor, Special Issue of Photochemistry and Photobiology (Vol. 33, No. 4)

Editorial Board, Methods in Enzymology Vols. 81 , 88

Associate Editor, Photochemistry and Photobiology, 1985 - 1988

Associate Editor, Biophysical Journal, 1991-1999

Review Panels

Ad Hoc Member, National Institutes of Health Study Section, 1975, 1977, 1980, 1986, 1989

Member, NSF Panel -- Mol. and Cell. Neurobiology, 1981 to 1984

Hughes Predoctoral Fellowship Panel, 1995, 1998, 1999

PUBLICATIONS (EXCLUDING ABSTRACTS)

Ebrey, T.G. and Gray, P.R. (1965) Precision half-live measurements of fourteen positron emitting nuclei. Nuc. Phys., 61, 479-492.

Gray, P.R., Zander, A.R. and Ebrey, T.G. (1965) Activation cross sections for reaction of argon with 14.7 Mev neutrons. Nuc. Phys., 62, 172-176.

Cone, R.A. and Ebrey, T.G. (1965) Functional independence of the two major components of the rod electroretinogram. Nature, 206, 913-915.

Pak, W.L. and Ebrey, T.G. (1965) Visual receptor potential observed at sub-zero temperatures. Nature, 205, 484-486.

Zander, A.R., Gray, P.R. and Ebrey, T.G. (1966) Gamma decay of 102Tc and104Tc. Nuc. Phys., 75, 209-214.

Gray, P.R., Zander, A.R. and Ebrey, T.G. (1966) Activation cross sections for reaction of Rh and Ru with 14.7 Mev neutrons. Nuc. Phys., 75, 215-225.

Pak, W.L. and Ebrey, T.G. (1966) Early receptor potentials for rods and cones in rodents. J. Gen. Physiol., 49, 1199-1208.

Ebrey, T.G. and Cone, R.A. (1967) Melanin: A possible pigment for the photo-stable electrical responses of the eye. Nature, 213, 360-362.

Pak, W.L., Rozzi, V.P. and Ebrey, T.G. (1967) Effect of changes in the chemical environment of the retina on the two components of the early receptor potential. Nature, 214, 109-110.

Ebrey, T.G. (1967) Fast light-evoked potential from leaves. Science, 155, 1556-1557.

Ebrey, T.G. (1967) Change transfer complexes of polyenes. J. Phys. Chem., 71, 1963-1964.

Ebrey, T.G. and Platt, J.R. (1967) First stage electrical events in vision. Science, 158, 527.

Ebrey, T.G. (1968) Characterization of the fast light-evoked electrical responses from leaves. Photochem. Photobiol., 7, 297-309.

Ebrey, T.G. (1968) The thermal decay of the intermediates of rhodsopsin in situ. Vision Res., 8, 965-982.

Ebrey, T.G. and Clayton, R.K. (1969) Phycomyces; Stimulus storage in light-initated reactions. Science, 164, 427-428.

Ebrey, T.G. and Clayton, R.K. (1969) Polarization of fluorescence from bacterio-chlorophyll in castor oil, in chromatophores and as P870 in photosynthetic reaction centers. Photochem. Photobiol., 10, 109-117.

Ebrey, T.G. (1971) Anomalous energy transfer behavior of light absorbed by bacterio-chlorophyll in several photosynthetic bacteria. Biochim. Biophys.Acta, 253, 385-395.

Ebrey, T.G. (1971) The use of ammonyx L0 in the purification of rhodopsin and rod outer segments. Vision Res., 11, 1007-1009.

Ebrey, T.G. (1971) Energy transfer in rhodopsin, N-retinyl-opsin, and the rod outer segments. Proc. Natl. Acad. Sci. USA, 68, 713-716.

Ebrey, T.G. (1972) The fluorescence from the tryptophans of rhodopsin. Photochem. Photobiol., 15, 585-588.

Ebrey, T.G. and Honig, B. (1972) Ultraviolet chromophore transitions in the rhodopsin spectrum. Proc. Natl. Acad. Sci. USA, 69, 1897-1899.

Ebrey, T.G. and Hood, D. (1973) The effects of cyclic nucleotide phosphodiesterase inhibitors on the frog rod receptor potential. In: Biochemistry and Physiology of Visual Pigments (H. Langer, ed.) Springer-Verlag pp. 341-350.

Ebrey, T.G. and Yoshizawa, T. (1973) The circular dichroism of rhodopsin and lumirhodopsin. Expt. Eye Res., 17, 545-556.

Honig, B., Kahn, P. and Ebrey, T. (1973) Intrinsic optical activity of retinal isomers: Implications for the circular dichroism spectrum of rhodopsin. Biochemistry, 12, 1637-1643.

Hood, D. and Ebrey, T. (1974) On the possible role of cAMP in receptor dark adaptation. Vision Res., 14, 437-440.

Honig, B. and Ebrey, T. (1974) The structure and spectra of the chromophore of the visual pigments. Ann. Rev. Biophys. Bioeng., 3, 151-177.

Chan, W., Nakanishi, K., Ebrey, T. and Honig, B. (1974) Properties of 14-Me retinal, 13-DesMe-14Me retinal, and visual pigments formed therefrom. J. Am. Chem.Soc., 96, 3642-3644.

Ebrey, T. and Honig, B. (1975) Molecular aspects of photoreceptor function. Quart. Rev. Biophys., 8, 129-184.

Ebrey, T., Govindjee, R., Honig, B., Pollock, E., Chan, W., Crouch, R., Yudd, T. and Nakanishi,K. (1975) Properties of several sterically modified retinal analogs and their photosensitivepigments. Biochemistry, 14, 3933-3941.

Crouch, R., Purvin, V., Nakanishi, K. and Ebrey, T. (1975) Isorhodopsin II: Artifical photosensitive pigment formed from 9, 13-dicis retinal. Proc. Natl. Acad. Sci. USA, 72, 1538-1542.

Greenberg, A., Honig, B. and Ebrey, T. (1975) Wavelength dependence of the band widths of visual pigment spectra. Nature, 257, 823-824.

Nakanishi, K., Yudd, A., Crouch, R., Olson, G., Cheung, H.C., Govindjee, R., Ebrey, T. and Patel, D. (1976) Allenic retinals and visual pigment analogues. J. Am. Chem. Soc., 98, 236-238.

Becher, B. and Ebrey, T. (1976) Evidence for chromophore-chromophore (Exciton) interaction in the purple membrane of Halobacterium halobium. Biochem. Biophys. Res. Comm., 69, 1-6.

Alfano, R., Yu, W., Govindjee, R., Becher, B. and Ebrey, T. (1976) Picosecond kinetics of the fluorescence from the chromophore of the purple membrane protein of Halobacterium halobium. Biophys. J., 16, 541-545.

Honig, B., Greenberg, A., Dinur, U. and Ebrey, T. (1976) Visual pigment spectra: Implications of the protonation of the retinal Schiff base. Biochemistry, 15, 4593.

Ebrey, T. and Honig, B. (1977) New wavelength dependent visual pigment nomograms. Vision Res., 17, 147-151.

Becher, B. and Ebrey, T. (1977) The quantum efficiency for the photochemical conversion of the purple membrane protein. Biophys. J., 17, 185-191.

Ebrey, T. and Yoshizawa, T. (1977) Structure and function of visual pigments. Report on the USA-Japan Cooperative Science Seminar. Expt. Eye Res., 24, 57-61.

Rosenfeld, T., Honig, B., Ottolenghi, M., Hurley , J. and Ebrey, T. (1977) Cis-trans isomerization in the photochemistry of vision. Pure Appl. Chem., 49, 341-351.

Ebrey, T., Becher, B., Mao, B., Kilbride, P and Honig, B. (1977) Exciton interactions and chromophore orientation in the purple membrane. J. Mol. Biol., 112, 377-397.

Aton, B., Doukas, A. Callender, R., Becher, B. and Ebrey, T. (1977) Resonance Raman studies of the purple membrane. Biochemistry, 16, 2995-2999.

Tokunaga, F., Govindjee, R., Ebrey, T. and Crouch, T. (1977) Synthetic pigment analogues of the purple membrane protein. Biophys. J., 19, 191-198.

Hurley, J., Ebrey, T., Honig, B. and Ottolenghi, M. (1977) Temperature and wavelength effects on the photochemistry of rhodopsin, isorhodopsin, bacteriorhodopsin, and their photoproducts. Nature, 270, 540-542.

Tokunaga, F. and Ebrey, T. (1978) The blue membrane: The 3-dehydro-retinal based artificial pigment of the purple membrane. Biochemistry, 17, 1915-1922.

Hurley, J. and Ebrey, T. (1978) Energy transfer in the purple membrane of Halobacterium halobium . Biophys. J., 22, 49-66.

Govindjee, R., Becher, B. and Ebrey, T. (1978) The fluorescence from the chromophore of the purple membrane protein. Biophys. J., 22, 67-77.

Doukas, A., Aton, B., Callender, R. and Ebrey, T. (1978) Resonance Raman studies of bovine metarhodopsin I and metarhodopsin II. Biochemistry, 17, 2430-2435.

Becher, B., Tokunaga, F. and Ebrey, T. (1978) Ultraviolet and visible absorption spectra of the purple membrane protein and the photocycle intermediates. Biochemistry, 17, 2293-2300.

Hurley, J., Becher, B. and Ebrey, T. (1978) More evidence that light isomerises the chromophore of purple membrane protein. Nature, 272, 87-88.

Aton, B., Doukas, A., Callender, R., Becher, B. and Ebrey, T. (1979) Resonance Raman study of the dark-adapted form of the purple membrane protein. Biochim. Biophys. Acta, 576, 424-428.

Kilbride, P. and Ebrey, T. (1979) Light-initiated changes of cyclic guanosine monophosphate levels in the frog retina measured with quick freezing techniques. J. Gen. Physiol., 74, 415-426.

Honig, B., Ebrey, T., Callender, R., Dinur, U. and Ottolenghi, M. (1979) Photoisomerization, energy storage, and charge separation: A model for light energy transduction in visual pigments and bacteriorhodopsin. Proc. Natl. Acad. Sci. USA, 76, 2503-2507.

Iwasa, T., Tokunaga, F., Yoshizawa, T., Ebrey, T. (1980) Quantum efficiency for the photoconversion of bacteriorhodopsin at very low temperatures. Photochem. Photobiol., 31, 83-85.

Honig, B., Dinur, U., Birge, R. and Ebrey, T. (1980) The isomer dependence of oscillator strengths in retinal and related molecules. Spectroscopic assignments. J. Am. Chem. Soc., 102, 488-494.

Tsuda, M. and Ebrey, T. (1980) Effect of high pressure on the absorption spectrum and isomeric composition of bacteriorhodopsin. Biophys. J., 30, 149-158.

Mao, B., Ebrey, T. and Crouch, R. (1980) Bathoproducts of rhodopsin, isorhodopsin I, and isorhodopsin II. Biophys. J., 29, 247-256.

Calhoon, R., Tsuda, M. and Ebrey, T. (1980) A light-activated GTPase from octopus photoreceptors. Biochem. Biophys. Res. Commun., 94, 1452-1457.

Ebrey, T., Tsuda, M., Sassenrath, G., West, J.L. and Waddell, W.H. (1980) Light activation of bovine rod phosphodiesterase by nonphysiological visual pigments. FEBS Lett., 116, 217-219.

Govindjee, R., Ebrey, T. and Crofts, A.R. (1980) The quantum efficiency of proton pumping by the purple membrane of Halobacterium halobium. Biophys. J., 30, 231-242.

Tsuda, M., Tokunaga, F., Ebrey, T., Yue, K., Marque, J. and Eisenstein, L. (1980) The behavior of octopus rhodopsin and its photoproducts at very low temperatures. Nature, 287, 461-462.

Mao, B., Tsuda, M., Ebrey, T., Akita, M., Balogh-Nair, V. and Nakanishi, K. (1981) Flash photolysis and low temperature phototchemistry of bovine rhodopsin with a fixed 11-ene. Biophys. J., 35, 543-546.

Tsuda, M., Glaccum, M., Nelson, B. and Ebrey, T. (1980) Light isomerizes the chromophore of bacteriorhodopsin. Nature, 287, 351-353.

Mao, B., Govindjee, R., Ebrey, T. Arnaboldi, M., Balogh-Nair, V., Nakanishi, K. and Crouch, R. (1981) Photochemical and functional properties of bacteriorhodopsins formed from 5,6-dihydro and 5,6-dihydrodesmethyl retinals. Biochemistry, 20, 428-435.

Ebrey, T., Kilbride, P., Hurley, J., Calhoon, R. and Tsuda, M. (1981) Light control of cyclic nucleotide concentration in the retina. In: Current Topics in Membranes and Transport, Vol. 15, pp. 121-132.

Iwasa, T., Tokunaga, F., Ebrey, T. and Yoshizawa, T. (1981) The photoreactions and photosensitivity of 3,4 Dehydro-bacteriorhodopsin at low temperatures. Photochem. Photobiol., 33, 547-557.

Narva, D.L., Callender, R.H. and Ebrey, T.G. (1981) Low temperature resonance Raman study of the L intermediate of bacteriorhodopsin. Photochem. Photobiol., 33, 567-571.

Tokunaga, F., Ebrey, T. and Crouch, R. (1981) Purple membrane analogs synthesized from C17 aldehyde. Photochem. Photobiol., 33, 495-499.

Renk, G., Grover, T., Crouch, R., Mao, B. and Ebrey, T. (1981) A spin labeled retinal pigment analogue of the purple membrane. Photochem. Photobiol., 33, 489-494.

Hurley, J., Barry, B. and Ebrey, T. (1981) Isolation of an inhibitory protein for the cyclic guanosine 3',5'-monophosphate phosphodiesterase of bovine rod outer segments. Biochim. Biophys. Acta, 675, 359-365.

Crouch, R., Ebrey, T. and Govindjee, R. (1981) A bacteriorhodopsin analogue containing the retinal nitroxide free radical. J. Am. Chem. Soc., 103, 7364-7366.

Pande, J., Callender, R. and Ebrey, T. (1981) Resonance Raman study of the primary photochemistry of bacteriorhodopsin. Proc. Natl. Acad. Sci. USA, 78, 7379-7382.

Ebrey, T. (1982) Primary events in bacteriorhodopsin. In: Picosecond Phenomena in Biology (R. Alfano, ed.) Academic Press, New York pp. 271-280.

Ebrey, T. (1982) Light energy transduction in Halobacterium halobium. In: Membranes and Transport, Vol. 2 (A. Martonosi, ed.) Plenum Press, New York, pp. 323-330.

Govindjee, R., Ohno, K. and Ebrey, T. (1982) Effect of the removal of the C-terminal region of bacteriorhodopsin on its light induced H+ changes. Biophys. J., 38, 85-87.

Ebrey, T. (1982) Synthetic pigments of rhodopsin and bacteriorhodopsin. Methods in Enzymology, 88, 516-521.

Honig, B. and Ebrey, T. (1982) Protein-chromophore interactions as spectroscopic and photochemical determinants. Methods in Enzymology, 88, 462-470.

Ohno, K., Govindjee, R. and Ebrey, T.G. (1983) Blue-light effect on proton pumping by bacteriorhodopsin. Biophys. J., 43, 251-254.

Tsuda, M., Govindjee, R. and Ebrey, T.G. (1983) Effects of pressure and temperature on the M412 intermediate of the bacteriorhodopsin photocycle: Implications for the phase transition of the purple membrane. Biophys. J., 44, 249-254.

Pande, A.J., Callender, R.H., Ebrey, T.G. and Tsuda, M. (1984) Resonance Raman study of the primary photochemistry of visual pigments. Biophys. J., 45, 573-576.

Govindjee, R., Ohno, K., Chang, C.-H. and Ebrey, T. (1984) The C-terminal tail of bacteriorhodopsin - its role in proton pumping. In: Information and Energy Transduction in Biological Membranes (C. Bolis, E. Helmreich, H. Passow, eds.), Alan R. Liss, New York, pp. 13-25.

Li, Q.-g., Govindjee, R. and Ebrey, T. (1984) A correlation between proton pumping and the bacteriorhodopsin photocycle. Proc. Natl. Acad. Sci. USA, 81, 7079-7082.

Chang, C.-H., Chen, J.-G., Govindjee, R. and Ebrey, T. (1985) Cation binding by bacteriorhodopsin. Proc. Natl. Acad. Sci., USA, 82, 396-400.

Crouch, R.K., Or, Y.S., Ghent, S., Chang, C.-H., Govindjee, R., Ebrey, T.G., Callender, R.H. and Pande, A. (1985) Neither the retinal ring nor the ring double bond is required for proton pumping in bacteriorhodopsin: acyclic retinal bacteriorhodopsin analogues. J. Am. Chem. Soc., 106, 8325-8327.

Schiffmiller, R., Callender, R.H., Waddell, W., Govindjee, R., Ebrey, T.G., Kakitani, H., Honig, B. and Nakanishi, K. (1985) Resonance Raman studies of bacteriorhodopsin analogues. Photochem. Photobiol., 41, 463-467.

Deng, H., Pande, C., Callender, R.H. and Ebrey, T.G. (1985) Detailed resonance Raman study of the M412 intermediate in the bacteriorhodopsin photocycle. Photochem. Photobiol., 41, 467-470.

Chang, C.-H., Govindjee, R., Ebrey, T.G., Bagley, K., Dollinger, G., Eisenstein, L., Marque, J., Roder, H., Vittitow, J., Fang, J.-M. and Nakanishi, K. (1985) Trans/13-cis isomerization is essential for both the photocycle and proton pumping of bacterio-rhodopsin. Biophys. J., 47, 509-512.

Tsuda, M., Nelson, B., Chang, C.-H., Govindjee, R. and Ebrey, T (1985) Characterization of the chromophore of the third rhodopsin-like pigment of Halobacterium halobium and its photoproduct. Biophys. J., 47, 721-724.

Bagley, K., Balogh-Nair, V., Croteau, A., Dollinger, G., Ebrey, T.G., Eisenstein, L., Hong, M. K., Nakanishi, K. and Vittitow, J. (1985) Fourier-transform infrared difference spectroscopy of rhodopsin and its photoproducts at low temperature. Biochemistry, 24, 6055-6071.

Govindjee, R. and Ebrey, T. (1986) Light emission from bacteriorhodopsin and rhodopsin. In: Light Emission by Plants and Bacteria (D. Fork and Govindjee, eds.), Academic Press, New York. pp 401-419.

Pande, C., Callender, R.H., Chang, C.-H. and Ebrey, T.G.(1986) Resonance Raman spectra of the "blue" and the regenerated "purple" membranes of Halobacterium halobium, Photochem., Photobiol., 42, 549-52.

Chang, C.-H., Jonas, R., Melchiore, S., Govindjee, R. and Ebrey, T.G. (1986) Mechanism and role of divalent cation binding of bacteriorhodopsin. Biophys. J., 49, 731-739.

Tsuda, M., Tsuda, T., Terayama, Y., Fukada, Y., Akino, T., Yamanaka, G., Stryer, L., Katada, T., Ui, M. and Ebrey, T.G. (1986) Kinship of cephalopod photoreceptor G-protein with vertebrate transducin. FEBS Lett., 198, 5-10.

Crouch, R., Scott, R., Ghent, S., Chang, C.-H., Govindjee, R. and Ebrey, T.G. (1986) Properties of synthetic bacteriorhodopsin pigments. Further probes of the chromophore binding site. Photochem. Photobiol., 43, 297-303.

Zingoni, J., Or, Y.-S., Crouch, R., Chang, C.-H., Govindjee, R., Ebrey, T. (1986) The effect of variation of retinal polyene side chain length on formation and function of bacteriorhodopsin analogue pigments. Biochemistry, 25, 2022-2027.

Pande, C., Callender, R.H., Chang, C.-H. and Ebrey, T.G. (1986) Resonance Raman study of the pink membrane photochemically prepared from the deionized blue membrane of H. halobium. Biophys. J., 50, 545-549.

Li, Q., Govindjee, R. and Ebrey, T.G. (1986) A proton release site on the C-terminal side of bacteriorhodopsin. Photochem. Photobiol., 44, 515-518.

Marque, J., Kinosita, K. Jr., Govindjee, R., Ikegami, A., Ebrey, T.G., Otomo, J. (1986) Environmental modulation of C-terminus dynamic structure in bacteriorhodopsin. Biochemistry, 25, 5555-5559.

Koutalos, Y. and Ebrey, T.G. (1986) Recent progress in vertebrate photoreception. Photochem. Photobiol., 44, 809-817.

Dancshazy, Z., Govindjee, R., Nelson, B., Ebrey, T.G. (1986) A new intermediate in the photocycle of bacteriorhodopsin. FEBS Lett., 209, 44-48.

Dancshazy, Z., Govindjee, R., Nelson, B., Ebrey, T.G. (1987) The M412's have decayed; BR570 has not recovered; Where is the pigment? In: Retinal Proteins (Y. Ovchinnikov, ed.) VNU Science Press, Utrecht, 485-494.

Liu, S.-Y. and Ebrey, T.G. (1987) A new method to prepare blue membrane by removing the cations from the purple membrane by electrolysis. Photochem. Photobiol., 46, 557-559.

Liu, S.-Y. and Ebrey, T.G. (1987) The quantum efficiency for the interphotoconversion of the blue and pink forms of purple membrane. Photochem. Photobiol., 46, 263-267.

Pande, C., Pande, A., Yue, K.T. and Callender, R., Ebrey, T.G., Tsuda, M. (1987) Resonance raman spectroscopy of octopus rhodopsin and its photoproducts. Biochemistry, 26, 4941-4947.

Dancshazy, Z., Govindjee, R. and Ebrey, T.G. (1987) Characterization of the new intermediate R in the bacteriorhodopsin photocycle. In: Biophysical Studies of Retinal Proteins (T. Ebrey, H. Frauenfelder, B. Honig and K. Nakanishi, eds.) U of Illinois Press, pp. 167-173.

Renk, G., Goletz, P., Crouch, R.K., Chang, C.-H., Govindjee, R. and Ebrey, T.G. (1987) A spin-labeled analogue of purple and blue membrane. In: Biophysical Studies of Retinal Proteins (T. Ebrey, H. Frauenfelder, B. Honig and K. Nakanishi, eds.) U of Illinois Press, 80-85.

Chang, C.-H., Jonas, R., Ebrey, T.G., Hong, M. and Eisenstein, L. (1987) Protonation changes in the interconversions of the pink membrane, blue membrane and purple membrane. In: Biophysical Studies of Retinal Proteins (T. Ebrey, H. Frauenfelder, B. Honig and K. Nakanishi, eds.) U of Illinois Press, 156-166.

Marque, J., Kinosita, K., Ikegami, A., Otomo, J., Govindjee, R. and Ebrey, T.G. (1987) Dynamic structure of the C-terminus of bacteriorhodopsin as probed with fluorescence anisotropy decay. In: Biophysical Studies of Retinal Proteins (T. Ebrey, H. Frauenfelder, B. Honig and K. Nakanishi, eds.) U of Illinois Press, 95-100.

Ebrey, T., Frauenfelder, H., Honig, B. and Nakanishi, K. (1987) Biophysical Studies of Retinal Proteins, University of Illinois Press.

Chang, C.-H., Jonas, R., Govindjee, R. and Ebrey, T.G. (1988) Regeneration of blue and purple membranes from deionized bleached membranes of Halobacterium halobium. Photochem. Photobiol., 47, 261-265.

Liu, S. Y., Ebrey, T. G. (1988) Photocurrent measurements of the purple membrane oriented in a polyacrylamide gel. Biophys. J., 54, 321-329.

Govindjee, R., Dancshazy, A., Ebrey, T. G., Longstaff, C., Rando, R. R. (1988) Photochemistry of methylated rhodopsins. Photochem. Photobiol., 48, 493-496.

Ohtani, H., Kobayashi, T., Tsuda, M. and Ebrey, T.G. (1988) Primary processes in photolysis of octopus rhodopsin. Biophys. J., 53, 17-24.

Govindjee, R., Dancshazy, A., Ebrey, T. G., Longstaff, C., Rando, R. R. (1988) Photochemistry of monomethylated and permethylated bacteriorhodopsin. Biophys. J., 54, 557-562.

Apte, D.V., Koutalos, Y., McFarlane, D.K., Dawson, M.J. and Ebrey, T.G. (1988) Phosphorus-31 nuclear magnetic resonance spectroscopic studies of toad retina. In: Molecular Physiology of Retinal Proteins (ed. T. Hara) Osaka, Japan, pp. 209-215.

Ohtani, H., Kobayashi, T., Tsuda, M. and Ebrey, T.G. (1988) Photochemical primary process of octopus rhodopsin. In: Fast Reactions in Biol. Systems (Ed. T. Kobayashi) Kyoto, Japan, pp. 92-100.

Dancshazy, Z., Govindjee, R. and Ebrey, T. G. (1988) Independent photocycles of the spectrally distinct forms of bacteriorhodopsin. Proc. Natl. Acad. Sci. U.S.A. 85, 6358-6361.

Bagley, K., Eisenstein, K., Ebrey, T. and Tsuda, M. (1989) A comparative study of the infrared difference spectra for octopus and bovine rhodopsins and their bathorhodopsin photointermediates. Biochemistry, 28, 3366-3373.

Chen, J. G., Nakamura, T., Ebrey, T. G., Odashima, K., Konno, K., Dergiuni, F. and Nakanishi, K. (1989) Wavelength regulation in iodopsin, a cone pigment. Biophys. J., 55, 725-729.

Apte, D. V., Koutalos, Y., McFarlane, D. K., Dawson, M. J. and Ebrey, T.G. (1989) 31P NMR spectroscopy of living toad retina. Biophys. J., 56, 447-452.

Koutalos, Y., Ebrey, T., Tsuda, M., Odashima, K., Lien, T., Derguini, F., Park, M.H., Gilson, H.R., Honig, B. and Nakanishi, K. (1989) Regeneration of bovine and octopus rhodopsin in situ with natural and artificial retinals. BIochemistry, 28, 2732-2739.

Chen, J., Nakamura, T., Ebrey, T. G. and Matsumoto, H. (1989) Monoclonal antibodies specific to chicken iodopsin. Vision Research, 29, 1267-1276.

Govindjee, R., Dancshazy, Z. and Ebrey, T.G. (1989) Difference spectra of the late intermediates of the bacteriorhodopsin photocycle. SPIE Proceedings, 1057, 126-137.

Ehrenberg, B., Ebrey, T. G., Friedman, N. and Sheves, M. (1989) Surface potential on the purple membrane measured using a modified bacteriorhodopsin chromophore as the spectroscopic probe. FEBS Letters, 250, 179-182.

Liu, S.Y., Govindjee, R. and Ebrey, T.G. (1990) Light induced currents from oriented purple membrane: II. Proton and cation contributions to the photocurrent. Biophys. J., 57, 951-963.

Koutalos, Y., Ebrey, T.G., Rodman-Gilson, H. and Honig, B. (1990) Octopus photoreceptor membranes: Surface charge density and pK of the Schiff base of the pigments. Biophys. J., 58, 493-501.

Tierno, M.E., Mead, D., Asato, A.E., Liu, R.S.H., Sekiya, N., Yoshihara, K.,Chang, C-W., Nakanishi, K., Govindjee, R. and Ebrey, T.G. (1990) 14-Fluoro-bacterio-rhodopsin and other fluorinated and 14-substituted analogs. An extra, usually red-shifted pigment formed during dark adaptation. Biochemistry, 29, 5948-5953.

Govindjee, R., Balashov, S.P. and Ebrey, T.G. (1990) Quantum efficiency of the photochemical cycle of bacteriorhodopsin. Biophys. J., 58, 597-608.

Jonas, R., Koutalos, Y. and Ebrey, T.G. (1990) Purple membrane: Surface charge density and the multiple effects of pH and cations. Photochem. Photobiol., 52, 1163-1177.

Jonas, R. and Ebrey, T.G. (1991) Binding of a single divalent cation directly correlates with the blue-to-purple color transition in bacteriorhodopsin. Proc. Natl. Acad. Sci. USA, 88, 149-153.

Deng, H., Manor, D., Weng, G., Rath, P., Koutalos, Y., Ebrey, T., Gebhart, R., Lugtenburg, J., Tsuda, M., Callender, R.H. (1991) Resonance Raman studies of the HOOP modes in octopus bathorhodopsin with deuterium labeled retinal chromophores. Biochemistry, 30, 4495-4502.

Liu, S.Y., Kono, M. and Ebrey, T.G. (1991) Effect of pH buffer molecules on the light-induced currents from oriented purple membrane. Biophys. J., 60,204-216.

Balashov, S.P., Govindjee, R. and Ebrey, T.G. (1991) Red shift of the purple membrane absorption band and the deprotonation of tyrosine residues at high pH. Biophys. J., 60, 475-490.

Beischel, C.J., Mani, V., Govindjee, R., Ebrey, T.G., Knapp, D.R., Crouch, R.K. (1991) Ring oxidized retinals form unusual bacteriorhodopsin analogue pigments. Photochem. Photobiol., 54, 977-984.

Balashov, S.P., Imasheva, E.S., Govindjee, R. and Ebrey, T.G. (1991) Quantum yield ratio of the forward and back light reactions of bacteriorhodopsin at low temperature and the photosteady-state concentration of the bathoproduct K. Photochem. Photobiol., 54, 955-961.

Balashov, S.P., Karneyeva, N.V., Litvin, F.F. and Ebrey, T.G. (1991) Bathoproducts and conformers of all-trans and 13-cis-bacteriorhodopsin at 90 K. Photochem. Photobiol., 54, 949-953.

Deng, H., Manor, D., Weng, G., Rath, P., Koutalos, Y., Ebrey, T., Gebhart, R., Lugtenburg, J., Tsuda, M. and Callender, R.H. (1991) A resonance Raman study of octopus bathorhodopsin with deuterium labeled retinal chromophores. Photochem. Photobiol., 54, 1001-1008.

Kojima, D., Okano, T., Fukada, Y., Shichida, Y., Yoshizawa, T. and Ebrey, T. (1992) Cone visual pigments are present in gecko rods. Proc. Natl Acad. Sci., USA 89, 6841-6845.

Hazard, E.S., Govindjee, R., Ebrey, T.G., Crouch, R.K. (1992) Biosynthetic incorporation of m-fluoro-tyrosine into bacteriorhodopsin. Photochem. Photobiol. 56, 929-934.

Govindjee, R., Lukashev, E., Kono, M., Balashov, S.P., Soppa, J., Tittor, J., Oesterhelt, D. and Ebrey, T. (1992) Tyr57Asn mutant of bacteriorhodopsin: M formation and spectral transformations at high pH. In: Structures and Functions of Retinal Proteins (J. Rigaud, ed.) Vol. 221, pp. 115-118.

Balashov, S. P., Govindjee, R., Kono, M., Lukashev, E., Ebrey, T. G., Feng, Y., Menick, D. and Crouch, R. (1992) Arg82Ala mutant of bacteriorhodopsin expressed in H. halobium: Drastic decrease in the rate of proton release and effect on dark adaptation. In: Structures and Functions of Retinal Proteins (J. Rigaud, ed.) Vol. 221, pp. 111-114.

Balashov, S., Imasheva, E., Karneyeva, N., Litvin, F. and Ebrey, T. (1992) Conformers and multiple primary photoproducts of bacteriorhodopsin and N intermediate at low temperature. In: Structures and Functions of Retinal Proteins (J. Rigaud, ed.) Vol. 221, 119-122.

Ebrey, T.G. (1993) Light Energy Transduction in Bacteriorhodopsin In: Thermodynamics of Membrane Receptors and Channels, (M. Jackson, ed.), CRC Press, 353-388.

Apte, D., Ebrey, T. and Dawson, M. J. (1993) Decreased energy requirement of toad retina during light adaptation as demonstrated by 31P NMR, J. Physiol. 464, 291-306.

Balashov, S.P., Govindjee, R., Kono, M., Lukashov, E., Imasheva, E., Ebrey, T., Crouch, R., Menick, D. and Feng, Y. (1993) Effect of the R82A mutation in bacteriorhodopsin on dark adaptation, proton release, and the photochemical cycle. Biochemistry, 32, 10331-10343.

Kono, M., Misra, S., Ebrey, T. G. (1993) pH-dependence of proton release by bacteriorhodopsin, FEBS Letters 331, 31-34.

Liang, J., Govindjee, R. and Ebrey, T. (1993) Metarhodopsin intermediates of the Gecko cone pigment P521, Biochemistry, 32, 14187-93.

Govindjee, R., Balashov,S., Ebrey, T., Oesterhelt, D., Steinberg, G. and Sheves, M. (1994) Lowering the intrinsic pKa of the chromophore's Schiff base can restore light-induced deprotonation and proton release in the inactive Y57N mutant of bacteriorhodopsin. J. Biol. Chem. 269, 14353-14354.

Deng, H., Huang, L., Callender, R. and Ebrey, T. (1994) Evidence for a bound water molecule next to the retinal Schiff base in bacteriorhodopsin and rhodopsin: a resonance Raman study of the Schiff base hydrogen/deuteron exchange. Biophysical J. 66, 1129-36.

Lukashev, E., Govindjee, R., Kono, M., Ebrey, T., Sugiyama, Y. and Mukohata, Y. (1994) pH dependence of the absorption spectra and photochemical transformations of the archaerhodopsins. Photochem. Photobiol. 60, 69-76.

Beischel, C.J., Knapp, D., Govindjee, R. , Ebrey, T. and Crouch, R. (1994) Azidotetrafluorophenyl retinal analogue: synthesis and bacteriorhodopsin pigment formation. Photochem. Photobiol. 60, 64-68.

Liang, J., Sheves, M., Steinberg, G., Livnah, N., Tsuda, M. and Ebrey, T. (1994) The pKa of the protonated Schiff bases of gecko cone and octopus visual pigments, Biophysical J. 67, 848-854.

Jonas, R., Yuan, C. and Ebrey, T. (1994) Improved large scale purification of transducin and its a and bg subunits from frozen retinas. Preparative Biochemistry 24, 279-288.

Feng, Y., Menick, D., Katz. B., Beischel, C., Hazard, E., Misra, S., Ebrey, T. and Crouch, R. (1994) Probing of the Retinal Binding Site of Bacteriorhodopsin by Affinity Labeling. Biochemistry 33, 11624-11630.

Balashov, S. and Ebrey, T. (1994) Bacteriorhodopsin: Molecular mechanisms of transmembrane proton transfer. Spectrum 7, 1-9.

Lewis, J., Liang, J., Ebrey, T., Sheves, M. and Kliger, D. (1995) Chloride Effect on the Early Photolysis Intermediates of a Gecko Cone-type Visual Pigment. Biochemistry, 34, 5817-5823.

Ebrey, T.G. and Liang, J. (1995) The bleaching of visual pigments In: Handbook of Organic Photochemistry and Photobiology (P.S. Song, ed.), p. 1500-1508.

Govindjee, R., Kono, M., Balashov, S., Imasheva, E., Sheves, M. and Ebrey, T.. (1995) Effects of substitution of Tyr57 with Asn and Phe on the properties of bacteriorhodopsin, Biochemistry, 34, 4828-4838.

Balashov, S., Govindjee, R., Imasheva, E., Misra, S., Ebrey, T., Feng, Y., Crouch, R. and Menick, D., (1995) The two pKas of Aspartate-85 and control of thermal isomerization and proton release in the Arginine-82 to Lysine mutant of bacteriorhodopsin. Biochemistry 34, 8820-8834.

Tang, L., Ebrey, T. and Subramaniyam, S. (1995) Sequences and structures of retinal proteins. Israel J. of Chemistry (special issue) 35, 193-209.

Balashov, S., Imasheva, E., Govindjee, R. and Ebrey, T. (1996) Titration of Aspartate-85 in bacteriorhodopsin: what it says about chromophore isomerization and proton release. Biophysical J. 70, 473-481.

Govindjee, R., Misra, S., Balashov, S., Ebrey, T., Crouch, R. and Menick, D. (1996) Arginine-82 regulates the pKa of the group responsible for light-driven proton release in bacteriorhodopsin. Biophysical J. 71, 1011-1023.

Balashov, S., Imasheva, E., Govindjee, R., Sheves, M. and Ebrey, T. (1996) Evidence that Aspartate-85 has a higher pKa in all-trans than in 13-cis bacteriorhodopsin. Biophysical J. 71, 1973-1984.

Huang, H., Deng, H., Weng, G., Koutalos, Y., Ebrey, T., Groesbeek, M., Lugtenburg, J., Tsuda, M. and Callender, R. (1996) A resonance Raman study of the C=N configuration of octopus rhodopsin, bathorhodopsin and isorhodopsin. Biochemistry 35, 8504-8510.

Hatanaka, M., Sasaki, J., Kandori, H., Ebrey, T. Needleman, R., Lanyi, J. and Maeda, A. (1996) Effects of Arginine-82 on the interactions of internal water molecules in bacteriorhodopsin. Biochemistry 35, 6308-6312.

Misra, S., Ebrey, T., Crouch, R. and Menick, D. (1997) Charge movements in the 13-cis photocycles of the bacteriorhodopsin mutants R82K and R82Q. Photochem. Photobiol. 65, 1039-1044.

Govindjee, R., Imasheva, E., Misra, S., Balashov, S., Ebrey, T., Chen, N., Menick, D. and Crouch, R. (1997) Mutation of a surface residue, Lysine 129, reserves the order of proton release and uptake in bacteriorhodopsin, guanadinium hydrochloride restores it. Biophysical J. 72, 886-898.

Misra, S., Govindjee, R., Ebrey, T., Chen, N., Ma, J.-X. and Crouch, R. (1997) Proton uptake and release are rate-limiting steps in the photocycle of the bacteriorhodopsin mutant E204Q. Biochemistry 36, 4875-4883.

Misra, S., Martin, C., Kwon, O., Ebrey, T., Chen, N., Crouch, R. and Menick, D. (1997) Mutation of Arginine 134 to lysine alters the pKas of key groups involved in proton pumping by bacteriorhodopsin. Special Issue of Photochem. Photobiol. 66, 774-783.

Huang, L., Deng, H., Koutalos, Y., Ebrey, T., Groesbeek, M., Lugtenburg, J., Tsuda, M. and Callender, R. (1997) A resonance Raman study of the C=C stretch modes in bovine and octopus visual pigments with isotopically labeled retinal chromophores. Special Issue of Photochem. Photobiol. 66, 747-775.

Balashov, S., Imasheva, E., Ebrey, T., Chen, N., Menick, D. and Crouch, R. (1997) Glutamate 194 to Cysteine mutation inhibits fast light-induced proton release in bacteriorhodopsin. Biochemistry 36, 8671-8676.

Lewis, J., Liang, J., Ebrey, T., Sheves, M., Livnah, N., Kuwata, M., Jager, S. and Kliger, D. (1997) Early photolysis intermediates of gecko and bovine artificial visual pigments. Biochemistry 36, 14592-14600.

Yuan, C., Chen, H., Anderson, R., Kuwata, O. and Ebrey, T. (1998) The unique lipid composition of gecko photoreceptor outer segment membranes. Comparative Biochemistry and Physiology B 120, 785-789.

Crouch, R., Menick, D., Feng, Y., Govindjee, R. and Ebrey, T. (1999) Bacteriorhodopsin structure/function studies: Use of the demethyl retinal analogues for probing the Arg82Ala mutant. In: The Biology-Chemistry Interface: A Tribute to Koji Nakanishi (R. Cooper and J. Snyder, eds.). Marcel dekker, NY pp. 431-444.

Yuan, C., Kuwata, O., Misra, S., Liang, J., Balashov, S. and Ebrey, T. (1999) Chloride binding regulates the Schiff base pK in gecko P521 cone-type visual pigment. Biochemistry 38, 4649-4654.

Nakagawa, M., Iwasa, T., Kikkawa, S., Tsuda, M. and Ebrey, T. (1999) How vertebrates and invertebrates differ in their mechanism of visual excitation. Proc. Natl. Acad. Sci. USA 96, 6189-6192.

Balashov, S., Lu, M., Imasheva, E., Govindjee, R., Ebrey, T., Othersen III, B., Chen, Y., Crouch, R. and Menick, D. (1999) The proton release group of bacteriohodopsin controls the rate of the final step of its photocycle at low pH. Biochemistry 38, 2026-2039.

Imasheva, E., Balashov, S., Ebrey, T., Chen, N., Crouch, R. and Menick, D. (1999) Two groups control light-induced Schiff base deprotonation and proton affinity of Aspartate-85 in the Arg82His mutant of bacteriorhodopsin. Biophysical J. 77, 2750-2763.

Maeda, A., Tomson, F., Gennis, R., Ebrey, T. and Balashov, S. (1999) Chromophore-protein-water interacitons in the L intermediate of bacteriorhodopsin: FTIR study of the photoreaction of L at 80 K. Biochemistry 38, 8800-8807.

Das, J., Crouch, R., Govindjee, R., Balashov, S. and Ebrey, T. (1999) Studies on the pyrylretinal analogues of bacteriorhodopsin. Photochem. Photobiol. 70, 949-956.

Gennis, R. and Ebrey, T. (1999) Structural Biochemistry: Proton pump caught in the act. Science 286, 252-253.

Ebrey, T. (2000) The pK of the protonated Schiff base of visual pigments. In: Methods in Enzymology, p. 196-207.

Lu, M., Balashov, S., Ebrey, T., Chen, N., Chen, Y., Menick, D. and Crouch, R. (2000) Evidence for the rate of the final step in the bacteriorhodopsin photocycle being controlled by the proton release group: R134H mutant, Biochemistry 39, 2325-2331.

Maeda, A., Tomson, F., Gennis, R., Kandori, H., Ebrey, T., Balashov, S. (2000) Relocation of internal bound water in bacteriorhodopsin during the photoreaction of M at low temperature: An FTIR study. Biochemistry 39, 10154-10162.

Ebrey, T. and Koutalos, Y. (2000) Rod and cone photoreceptors: a review. Progress in Retinal and Eye Research 20, 49-94.

Ebrey, T. and Takahashi, Y. (2001) Photobiology in retinal proteins. (In press.)

Balashov, W. and Ebrey, T. (2001) Trapping and spectroscopic identification of the photointermediates of bacteriorhodopsin at low temperature. Photochem. Photobiol. 73, (in press).

Imasheva, E., Balashov, S., Ebrey, T., Chen, Y., Menick, D., and Crouch, R. (2001) Study of the function of Tyr83 in bacteriorhodopsin: Y83N and Y83F mutants. (Submitted)

Balashov, S. Lu, Miao, Imasheva, E., Ebrey, T., Chen, N., Chen, Y., Menick, D. and Crouch, R. (2001) Arg134 sets the pK of the proton release complex in bacteriorhodopsin. (In prep.)

Yuan, C. and Ebrey. T. (2000) Carbohydrates of a cone-type visual pigment. (In prep.)

Maeda, A., Balashov, S.P., Verhoeven, M.P., Lugtenburg, J., Tomson, F.L., Gennis, R.B. and Ebrey, T.G. (2001) Interaction of internal water molecules with the Schiff base of the L intermediate of bacteriorhoodopsin; FTIR studies using bacteriorhodopsin with isotopically-labeled retinal. (In prep.)

Lu, M., Balashov, S.P., Ebrey, T.G., Liu, J., Huang, L., Wang, Y., Huang, W., Ding, J. and Li, Q. (2001) Characterization of the photochemical properties of a newly isolated archaerhodopsin from a strain of Chinese halobacteria. (In prep.)

Lu, M., Govindjee, R., Balashov, S.P., Ebrey, T.G., Chen, Y, Menick, D.R., and Crouch, R.K. (2001) Ser193 and Thr205 are important components of the proton release pathway in bacteriorhodopsin (bR). (In prep.)

Papers from my laboratory which I am not a co-author

Hurley, J.B. (1980) Isolation and recombination of bovine rod outer segment cGMP phosphodiesterase and its regulators. Biochem. Biophys. Res. Commun., 92, 505-510.

Kilbride, P. (1980) Calcium effects on frog retinal cyclic guanosine 3',5'-monophosphate levels and their light-initiated rate of decay. J. Gen.Physiol.,75, 457-465.

Becher, B. (1980) The photoconversion of lumirhodopsin at 77ûK. Biophys. J., 30,1-8.

Mao, B. (1981) Thermal decay of the bathoproduct of bacteriorhodopsin. Photochem. Photobiol., 33, 407-411.

Chang, C.-H., Liu, S.-Y., Jonas, R. and Govindjee, R. (1987) The pink membrane, the stable photoproduct of deionized purple membrane. Biophys. J. 52, 617-623.

Govindjee, R., Chang, C. H., Dancshazy, Zsolt and Tsuda, Motoyuki. (1987) Photochemistry of Tyrosine-64 nitrated bacteriorhodopsin. In: Ebrey, T., Frauenfelder, H., Honig, B. and Nakanishi, K. (eds.) Biophysical Studies of Retinal Proteins. University of Illinois Press, 181-187.

Lin, S-L., Ormos, P., Eisenstein, L., Govindjee, R., Konno, K. and Nakanishi, K. (1987) Deprotonation of tyrosines in bacteriorhodopsin as studied by Fourier transform infrared spectroscopy with deuterium and nitrate labeling. Biochemistry, 26, 8327-8331.

Liu, S.-L. (1990) Light-induced currents from oriented purple membrane: I. Correlation of the microsecond component (B2) with the L-M photocycle transition. Biophys. J., 57, 943-950.

Koutalos, Y. (1992) High pH form of bovine rhodopsin, Biophys. J., 61, 272-275.

Wang, Y-M., Lee, H. and Apte, D.V. (1992) Quantative NMR spectroscopy by matrix pencil methods. International Journal of Imaging Systems and Technology, 4, 201-206.

Fitch, C., DeSousa, S., O'Day, P., Neubert, T., Plantilla, C., Spencer, M., Yarfitz, S., Apte, D. and Hurley, J. (1993) Pertussis toxin expression in Drosophila alters the visual response and blocks eating behavior. Cellular Signalling, 5, 187-207.

Fitch, C. and Apte, D. (1992) Levels of phosphorus metabolites in adult Drosphila expressing pertussis toxin were determined by 31-P NMR spectroscopy. Drosophila Information Newsletter 71, 238-239.

Balashov, S.P., Sumi, M. and Kamo, N. (2000) The M intermediate of Pharaonis Phoborhodopsin is photoactive. Biophys. J., 78, 3150-3159.

Balashov, S.P. (2000) Protonation reactions and their coupling in bacteriorhodopsin. Biochem. Biophys. Acta.

VISITING FACULTY AND POST-DOCS

Name	Title	Present Position
Barry Honig	Visiting Associate Professor Summers, 1974, 1975, 1976 Fall, 1978	Professor of Biochemistry at Columbia University
Motoyuki Tsuda	Visiting Associate Professor 1978-1980	Professor of Biology Himeiji Institute of Tech.
Fumio Tokunaga	Visiting Assistant Professor 1975-1977	Professor of Biology Osaka University
Qing-guo Li	Visiting Assistant Professor 1982-83; 1990-91	Associate Professor of Biophysics, Fudan University, Shanghai
Koki Ohno	Visiting Assistant Professor 1980-1982	Professor of Physics Jichi Medical School, Japan
Zsolt Danschazy	Visiting Research Associate 1985-1987	Senior Investigator BRC, Szeged, Hungary
Sergei Balashov	Visiting Professor 1988-1990; 1992-2001	Professor Moscow State University
Tatsuo Iwasa	Visiting Assistant Professor February, 1989	Associate Professor Himeiji Institute of Tech.
Masashi Nakagawa	Visiting Assistant Professor 1989-1990	Assistant Professor Himeji Institute of Tech.
Richard Lozier	Visiting Assistant Professor May, 1989	NIH, Bethersda, Md.
E.S. Imasheva	Visiting Assistant Professor June, July 1989; 1992-2001	Assistant Professor Moscow State University
V. Lukashev	Visiting Associate Professor 1991	Associate Professor Moscow State University
Mordecai Sheves	Visiting Associate Professor 1992-1993	Assoc. Prof. Weizmann Institute Rehovot, Isreal
Rajni Govindjee	Senior Research Associate 1973-1999	Retired
Brian Becher	Postdoctoral Fellow 1975-1978	M.D., In Practice
C.K. Suh	Postdoctoral Fellow 1985-1990	Professor, Head Dept. of Physiology and Biophysics, Inha Medical School, Inchon, S. Korea
Tadashi Nakamura	Postdoctoral Fellow 1986-1987	Assistant Professor of Physics Tokyo Electro-Communications University
Osamu Kuwata	Postdoctoral Fellow 1995-1998	Assistant Proffessor Tsukuba Univ., Tsukuba, Japan
Akio Maeda	Visiting Professor 1997-1998, 1998-2001	Prof. Emeritus, Kyoto University Presently in lab
Rainer Stahlberg	Senior Research Fellow	Presently in lab
Yusuke Takahashi	Postdoctoral Fellow	Presently in lab

GRADUATE STUDENTS

Name	Degrees	Present Position
Paul Kilbride 1973-1979	B.S. 1973, Iowa State Ph.D. 1979	President, Virtual World
Jim Hurley 1976-1979	B.S. 1975, Syracuse Ph.D. 1979	Associate Professor, HHMI University of Washington
Boryeu Mao 1975-1980	B.S. 1971, Taiwan Natl. Univ. Ph.D. 1980	Sr. Research Scientist, Upjohn
Roger Calhoon 1976-1983	B.S. 1976, Wittenburg Ph.D. 1985	Research Scientist, Genetech
Chung-ho Chang 1979-1985	B.S. 1977, Taiwan Natl. Univ. Ph.D. 1986	Assistant Professor Case-Western Reserve
Jian-guo Chen 1982-1988	B.S. 1981, N. Jiaotung Univ, (Beijing) Ph.D. 1988	Sr. Research Scientist BioGenex
Su-yi Liu 1983-1990	B.S. 1982, Qinghua Univ. (Beijing) Ph.D. 1990	Director, Chemical Res. WPI, Inc.
Ioannis Koutalos 1984-1990	B.S. 1984, Univ. of Athens Ph.d. 1990	Postdoctoral, Johns Hopkins University
Roy Jonas 1985-1991	B.S. 1984, University of Illinois Ph.D. 1990	Medical Student Southern Illinois University
Dipali Apte 1986-1991	B.S. 1984, University of Illinois Ph.D. 1991, M.D. 1992	Resident
Jie Liang 1987-1994	B.S. 1987, Fudan University (Shanghai); Ph.D. 1994	Postdoctoral University of Illinois
Masahiro Kono 1989-1994	B.S. 1986, MIT Ph.D. 1994	Postdoctoral, Brandeis University
Li Tang 1990-1996	B.S. 1989, Fudan University (Shanghai)	Postdoctoral Columbia University
Saurav Misra 1990-1997	B.S. 1991, Ohio University	Postdoctoral, NIH
Ching Yuan 1991-1998	B.S. 1987, Taiwan Natl. Univ.	Postdoctoral Fellow, Baylor Univ.
Miao Lu 1997-	B.S. 1997 Peking University	Presently in lab

UNIVERSITY OF ILLINOIS SERVICE
University and Campus:

1973-1974 Member, All-University Biophysics Review Committee

1974-1976 Member, Senior Biophysics Search Committee

1976-1977 Member, All-University Committee on Postdoctoral Fellows

1981-1984 Member, George A. Miller Endowment Committee

1984 Member, Ad Hoc Committee to Develop a Proposal to Arnold Beckman

1984-1986 Member, Graduate College Biological Sciences Area Subcommittee

1986-1987 Urbana-Champaign Senate

1989-1990 Member, Selection Committee for University Scholars

1991-1994 Organ. Comm., Beckman Sym. of Biol. Struct.

1992-1994 Member, Campus Budget Strategies Committee

1992- Member, Steering Committee, NSF Biomedical NMR Science Technology Center

1992- Program Director, Cell and Molecular Biology Training Grant

1993- Member, Steering Committee, Biotechnology Center

1993-1994 Member, Graduate College Comm. to Review Fellowship Policy

1993-1994 Member, Chancellor's Committee on Developing Resources for Sustained Excellence

1993-1994 Member, Chancellor's Committee on Improving the Quality of Graduate Education

College:

1987-1988 Chair, Committee to Review Director of School of Chemical Sciences

1989-1990 Member, College Executive Committee

1992 Member, Area Financial Strategies Committee

1993- Chair, Biochemistry Head Search Committee

School of Life Sciences:

1974 Chair, Plant Biophysics Search Committee

1981 Member, Biophysics Search Committee

1984-1986 Member, SOLS Space Committee

1984-1986 Member, SOLS Services Committee

1985-1986 Biophysics Search Committee

1986 X-ray Crystallographer Search Committee

1987-1988 Chair, Search Committee for Head of Plant Biology

1987-1988 Member, Search Comm. for Senior X-Ray Crystal.

1990-1991 Member, Search Comm. for Junior X-Ray Crystal.

1988- Member, Cell & Mol. Biology Training Grant Exec. Comm..

1988-1992 Faculty Advisor, Cell & Molecular Biology Tr. Gr. Symp.

1991-1992 SOLS Faculty Advisory Committee

1992- Member, Mol. Biophysics Training Grant. Exec. Comm.

1993- Member, Exec. Comm., Center for Biophysics and Computational Biology

Department of Physiology & Biophysics:

1980-1990 Member, Physiology and Biophysics Advisory Committee

1990 Chair, Prosser Lectureship Committee

Department of Cell and Structural Biology

1992- Member, Graduate Comm., Cell and Struct. Biol.

1992- Member, Distinction Comm., Cell and Struct. Biol.

Center for Biophysics and Computational Biology

1973-1979 Chair, Division of Biophysics

1973- Member, Biophysics Admissions Committee

1978-1990 Member, Biophysics Qualifying Examination Committee

1985-1986 Acting Chair, Division of Biophysics

1980-1992 Chair, Biophysics Courses & Curriculum Committee

1978-1992 Chair, Biophysics Graduate Student Advising