Timothy Thornton's Publications

Last updated 3 June 2014

  1. Conomos M, Miller M, Thornton TA (2015) Robust Inference of Population Structure for Ancestry Prediction and Correction of Stratification in the Presence of Relatedness Genetic Epidemiology 39 :276-93

  2. Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT Jr, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, Hsu L, Jackson RD, Jarvik GP, Kim DS, Lakshminarayan K, Lange LA, Manichaikul A, Quinlan AR, Singleton AB, Thornton TA , Nickerson DA, Peters U, Rich SS; National Heart, Lung, and Blood Institute Exome Sequencing Project (2015) Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. JAMA Neurology 72:781-788. doi:10.1001/jamaneurol.2015.0582

  3. Hong X, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA , Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, Singh AM, Kim JS, Story RE, Gupta RS, Gao P, Chen Z, Walker S, Bartell TR, Beaty TH, Fallin MD, Schleimer R, Holt PG, Nadeau KC, Wood RA, Pongracic JA, Weeks DE, Wang X (2015) Genome-wide Association Study of Food Allergy Identifies Peanut Allergy-Specific Susceptibility Loci and Evidence of Epigenetic Mediation in U.S. Children of European Ancestry Nature Communications 6:6304. doi: 10.1038/ncomms7304.

  4. Fohner AE, Robinson R, Yracheta J, Dillard D, Schilling B, Kahn B, Hopkins S, Boyer B, Black J, Gordon A, Nickerson D, Tsai J, Farin F, Thornton TA , Rettie AE, Thummel KE Variation in Genes Controlling Warfarin Disposition and Response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX Pharmacogenetics and Genomics 25:343-53

  5. Thornton TA (2015) Statistical methods for genome-wide and sequencing association studies of complex traits in related samples. Current Protocols in Human Genetics 84:1.28.1-9. doi: 10.1002/0471142905.hg0128s84.

  6. Thornton TA , Bermejo JL (2014) Local and Global Ancestry Inference and Applications to Genetic Association Analysis for Admixed Populations Genetic Epidemiology, 38 (S1): S5-S12

  7. Hoffman TJ, Tang H, Thornton TA , Caan BJ, Millen AE, Thomas F, Risch NJ (2014) Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative Human Molecular Genetics doi: 10.1093/hmg/ddu364

  8. Alam MT, Petit RA , Crispell EK, Thornton TA , Conneely KN, Jiang Y, Satola SW, Read TD (2014) Dissecting Vancomycin-Intermediate Resistance in Staphylococcus aureus Using Genome-Wide Association Genome Biol Evol 6(5): 1174-1185

  9. Thornton T , Conomos M, Sverdlov S, Marchani EE, Cheung C, Glazner C, Lewis S, Wijsman EM. (2014) Estimating and Adjusting for Ancestry Admixture in Statistical Methods for Relatedness Inference, Heritability Estimation, and Association Testing. BMC Proceedings 8:S5

  10. Marchani EE, Cheung CYK, Glazner CG, Conomos MP, Lewis SM, Sverdlov S, Thornton T, Wijsman EM. (2014) Identity-by-Descent Graphs Offer a Flexible Framework for Imputation and both Linkage and Association Analyses. BMC Proceedings 8:S19

  11. Thornton T , Austin M. (2013) Software and data resources for genetic association studies CAB Reviews 8 (057):1-6

  12. Coram M, Duan Q, Hoffman TJ, Thornton T , Knowles J, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ, Zhu X, Kooperberg C, Li Y, Reiner AP, Tang H. (2013) Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Human Populations American Journal of Human Genetics 92:904-916

  13. Perez MV, Hoffmann TJ, Tang H, Thornton T , Stefanick ML, Larson JC, Kooperberg K, , PhD, Reiner AP, Caan B, DrPH, Iribarren C, Risch N (2013) African-American race but not genome-wide African ancestry is negatively associated with atrial fibrillation among postmenopausal women American Heart Journal 166:566-572.e.1

  14. Fohner A, Muzquiz LI, Austin MA, Gaedigk A, Gordon A, Thornton T, Rieder MJ, Pershouse MA, Putnam EA, Howlett K, Beatty P, Thummel KE, Woodahl EL. (2013). Pharmacogenetics in American Indian Populations: Analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes. Pharmacogenetics and Genomics: 23:403-414

  15. Kaklamani VG, Hoffmann TJ, Thornton T, Geoffrey G, Chlebowski R, Horn LV6, Mantzoros C. (2013) Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women's Health Initiative Breast Cancer Research and Treatment 139:461-468

  16. Ochs-Balcom HM, Preus L, Wactawski-Wende J, Nie J, Johnson NA, Zakharia F, Tang H, Carlson C, Carty C, Chen Z, Hoffman T, Hutter CM, Jackson RD, Kaplan RC, Li L, Liu S, Neuhouser ML, Peters U, Robbins J, Seldin MF, Thornton T, Thompson CL, Kooperberg C, Sucheston LE (2013) Admixture Mapping of DXA-Derived Phenotypes in WHI SHARe African-Americans Journal of Clinical Endocrinology and Metabolism 98: E713-717

  17. Thornton T, Tang H, Hoffman TJ, Ochs-Balcom HM, Baan BJ, and Risch N (2012) Estimating Kinship in Admixed Populations American Journal of Human Genetics 91: 122-138

  18. Thornton T, Zhang Q, Cai X, Ober C, and McPeek MS (2012) XM: Association Testing on the X-Chromosome in Case-Control Samples with Related Individuals Genetic Epidemiology 36:438-450

  19. Tore S, Casula S, Casu G, Concas MP, Pistidda P, Persico I, Sassu A, Maestrale GM, Caterina Mele C, Caruso MR, Bonerba B, Usai P, Deiana I, Thornton T, Pirastu M, and Forabosco P (2011) Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasi PLoS Genetics 7(1): e1001281. doi:10.1371/journal.pgen.1001281

  20. Phasukijwattana N, Kunhapan B, Stankovich J, Chuenkongkaew WL, Thomson R, Thornton T, Bahlo M, Mushiroda T, Nakamura Y, Mahasirimongkol S, Tun AW, Srisawat C, Limwongse C, Peerapittayamongkol C, Sura T, Suthammarak W, Lertrit P (2010) Genome-wide Linkage Scan and Association Study of PARL to the Expression of LHON Families in Thailand Human Genetics 128: 39-49

  21. Thornton T., McPeek M. S. (2010) ROADTRIPS: Case-control association testing with partially or completely unknown population and pedigree structure American Journal of Human Genetics 86: 172-184

  22. FitzGerald LM, Patterson B, Thomson R, Polanowski A, Quinn S, Brohede J, Thornton T, Challis D, Mackey D, Dwyer T, Foote S, Hannan GN, Stankovich J, McKay JD, Dickinson JL (2009) Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease European Journal of Human Genetics 17: 368-377.

  23. Thornton T., McPeek M. S. (2007) Case-Control Association Testing with Related Individuals: A More Powerful Quasi-Likelihood Score Test American Journal of Human Genetics 81: 321-337

  24. Anderson-Cook CM and Thornton T (1998) "Response to Letter to the Editor: Shorthanded", Chance, 12: 3-5.

  25. Anderson-Cook CM and Thornton T (1998) "Measuring Hockey's Special Teams Efficiency", Chance, 11: 26-34

  26. Anderson-Cook CM, Thornton T, Robles R (1997) "Measuring Hockey Powerplay and Penalty Killing Efficiency", Proceedings of the American Statistical Association Section on Statistics in Sports, Alexandria, VA: American Statistical Association, 11-14.