I completed my MTech in Biotechnology from Department of Biotechnology, Indian

Institute of Technology, Kharagpur in 1998. Afterwards I received my PhD in 2003

from Department of Theoretical Physics at Indian Association for the Cultivation of

Science, Jadavpur, India under the supervision of Dr Jayprokas Chakrabarti. Presently

I work in the laboratory of Dr. Evgeni V. Sokurenko in Department of Microbiology,

University of Washington, Seattle, USA.

My research focus is the development of analytical tools to identify selection footprints 

of recent/short-term adaptive evolution through single nucleotide polymorphisms (SNPs)  

in the course of environmental pressures such as any sudden changes in the existing

environment or habitat differentiation. I am also interested in the use of linguistic tools in

sequence analysis.                                                        

Resources Developed

Zonal Phylogeny Software (ZPS) :

A visualization as well as analytic tool to dissect microevolutionary processes in microbial

pathogens or any other biological species:

* As a visualization tool, ZPS depicts the protein tree in a DNA tree, indicating the

most parsimonious numbers of synonymous and nonsynonymous changes along

the branches of a maximum-likelihood based DNA tree, along with information

on homoplasy, reversion and structural mutation hotspots.

* As an analytic tool, through zonal differentiation, ZPS allows detection of recent

adaptive evolution via selection of advantageous structural mutations, even

when the advantage conferred by such mutations is relatively short-term, as in the

case of 'source-sink' evolutionary dynamics, a characteristic of pathogenicity-adaptive

(pathoadaptive) evolution in microbes.