Publications
|
|
Goodman, T.T., Chen, J., Matveev, K., and Pun, S.H. (2008) Spatio-temporal modeling of nanoparticle delivery to multicellular spheroids. Biotech and Bioeng, in press.
|
|
Kwon, E.J., Bergen, J.M., and Pun, S.H. (2008) Application of an HIV gp41-derived peptide for enhanced intracellular trafficking of synthetic gene and siRNA delivery vehicles. Bioconj Chem v19(4):920-927.
|
|
Burke, R.S. and Pun, S.H. (2008) Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to liver. Bioconj Chem v19(3):693-704. |
|
Park, I.K., Ng, C.P., Wang, J., Chu, B.C., Wang, C., and Pun, S.H. (2008) Determination of nanoparticle vehicle unpackaging by MR imaging of a T2 magnetic relaxation switch. Biomaterials v29(6):724-732. |
|
Ng, C.P. and Pun, S.H. (2008) A versatile 3-D soft tissue perfusion chamber for mimicking tissue microenvironments. Biotech and Bioeng v99(6):1490-1501. |
|
Bergen, J.M., Kwon, E.J., Shen, T.W., and Pun, S.H. (2008) Application of an environmentally-sensitive fluorophore for rapid analysis of the binding and internalization of gene carriers. Bioconj Chem v19(1):377-384. |
|
Bergen, J.M. and Pun, S.H. (2008) Analysis of intracellular barriers encountered by non-viral gene carriers in a model of spatially-controlled delivery to neurons. J Gene Med v10(2):187-197. |
|
Saul, J.M., Wang, C.K., Ng, C.P., and Pun, S.H. (2008) Multilayer nanocomplexes of polymer and DNA exhibit enhanced gene delivery Advanced Materials v20(1):19-25. |
|
Bergen, J.M., Park, I.K., Horner, P.J., and Pun, S.H. (2008) Nonviral approaches for neuronal delivery of nucleic acids. Pharm Res v25(5):983-998. |
|
Rodriguez, V., Henry, S., Hoffman, A.S., Stayton, P.S., Li, X., and Pun, S.H. (2008) Polymeric micelle encapsulation of indocyanine green. J. Biomed Optics v13(1) 014025. |
|
Park, I.K., Lasiene, J., Chou, S.H., Horner, P.J., and Pun, S.H. (2007) Neuron-specific delivery of nucleic acids mediated by Tet1-modified poly(ethylenimine). J Gene Med v9:691-702.
|
|
Saul, J.M., Linnes, M.P., Ratner, B.D., Giachelli, C.M., and Pun, S.H. (2007) Delivery of non-viral gene carriers from sphere-templated fibrin scaffolds for sustained transgene expression. Biomaterials v28(31):4705-4716.
|
|
Housni, A., Cai, H., Liu, S., Pun, S.H, and Narain, R. (2007) Facile preparation of glyconanoparticles and their bioconjugation to streptavidin. Langmuir 23(9):5056-5061.
|
|
Goodman, T., Olive, P.L., Pun, S.H. (2007) Increased nanoparticle penetration in collagenase-treated multicellular spheroids. Int J Nanomed v2(2):265-274.
|
|
Bergen, J.M. and Pun, S.H. (2007) Evaluation of an LC8-binding motif for cargo attachment to dynein. Mol Pharm 4(1):119-128.
|
|
Cheng, J., Zeidan, R., Mishra, S., Liu, A., Pun, S.H., Kulkarni, R.P., Jensen, G.S., Bellocq, N.C., and Davis M.E. (2006) Structure-Function Correlation of Chloroquine and Analogues as Transgene Expression Enhancers in Nonviral Gene Delivery. Journal of Medicinal Chemistry, 49(22), 6522-6531.
|
|
Park, I.K., von Recum, H.A., and Pun, S.H. (2006) Supramolecular assembly of cyclodextrin-based nanoparticles on solid sufaces for gene delivery. Langmuir 22:8478-8484.
|
|
Bergen, J.M., von Recum, H.A., Goodman, T.T., Massey, A.P., and Pun, S.H. (2006) Gold nanoparticles as a versatile platform for optimizing physicochemical parameters for targeted drug delivery. Macromolecular Bioscience 6:506-516.
|
|
Popielarski, S.R., Pun, S.H., and Davis , M.E. (2005) A nanoparticle-based model delivery system to guide the rational design of gene delivery to the liver. 1. Synthesis and Characterization. Bioconjugate Chemistry 16:1063-1070.
|
|
Bergen, J.M. and Pun, S.H. (2005) Peptide-enhanced gene delivery. MRS Bulletin 30:663-667.
|
|
Pack, D.W., Hoffman, A.S., Pun, S.H., and Stayton, P.S. (2005) Design and Development of Polymers for Gene Delivery. Nature Reviews Drug Discovery 5:581-593.
|
|
Bellocq, N.C., Kang, D.W., Wang, X., Jensen, G.S., Pun, S.H., Schleup, T., Zepeda, M.L., and Davis, M.E. (2004) Synthetic biocompatible cyclodextrin-based constructs for local gene delivery to improve cutaneous wound healing. Bioconjugate Chemistry 15:1201-1211.
|
|
Pun, S.H., Bellocq, N.C., Liu, A., Machemer, T., Maneval, D.C., Quijano, E., Schluep, T., Wen, S., Engler, H., Heidel, J., and Davis, M.E. (2004) Cyclodextrin-poly(ethylenimine) polymers for gene delivery. Bioconjugate Chemistry 15:831-840.
|
|
Pun, S.H. and Davis, M.E. (2004) Cyclodextrin polymers for gene delivery, Chapter in Polymeric Gene Delivery, CRC Press, Mansoor Amiji, Ed.
|
|
Pun, S.H., Bellocq, N.C., Cheng, J., Grubbs, B.H., Jensen, G.S., Davis, M.E., Tack, F., Brewster, M., Janicot, M., Janssens, B., Floren, W., Bakker, A. (2004) Biodistribution of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles. Cancer Biology and Therapy 7:641-650.
|
|
Davis, M.E., Pun, S.H., Bellocq, N.C., Reineke, T.M., Popielarski, S.R., Mishra, S., and Heidel, J. (2004) Self-assemblying nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers. Current Medicinal Chemistry 11(2):179-197
|
|
Bellocq, N.C., Pun, S.H., Jensen, G.S. and Davis, M.E. (2003) Synthesis of transferrin-PEG conjugates and preparation of transferrin-modified polyplexes for tumor-targeted gene delivery. Bioconjugate Chemistry 14:1122-1132.
|
|
Pun, S.H. and Davis, M.E. (2002) Development of a Non-viral Gene Delivery Vehicle for Systemic Application. Bioconjugate Chemistry 13:630-639.
|
|
Hwang, S.J. and Davis, M.E. (2001) Cationic Polymers for Gene Delivery: Designs for Overcoming Barriers to Systemic Administration. Current Opinions in Molecular Therapeutics 3(2): 183-191.
|
|
Bellocq, N.C., Hwang, S.J., and Davis, M.E. (2001) Optimization of Cyclodextrin-Polymers Specifically Designed for Gene Delivery. Proceedings of the 221st American Chemical Society National Meeting, Polymeric Materials: Science & Engineering 84: 809-810.
|
|
Hwang, S.J., Bellocq, N.C., and Davis, M.E. (2001) Effects of Structure of beta-cyclodextrin-containing Polymers on Gene Delivery. Bioconjugate Chemistry 12(2): 280-290.
|
|
Gonzalez, H., Hwang, S.J., and Davis, M.E. (1999) New Class of Polymers for the Delivery of Macromolecular Therapeutics. Bioconjugate Chemistry 10: 1068-1074.
|
|
McDaniel, R., Kao, C., Hwang, S.J., and Khosla, C. (1997) Engineered Intermodular and Intramodular Polyketide Synthase Fusions. Chem. & Bio. v.4: 667-674.
|
|
