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Local Anesthetics IClassification, Mechanism of action, pharmacology of lidocaine and bupivacaineRecommended Reading Materials:– Chapter 17 of Clinical Anesthesia by Barash, Cullen, Stoelting, 5th edition. Local Anesthetics (Liu SS, Joseph RS) p 453-471. – Chapter 14 of Miller’s Anesthesia, 6th edition - Local Anesthetics (Charles B. Berde and Gary R. Strichartz) |
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Local Anesthetics IIPharmacology of Prilocaine, mepivacaine, ropivacaine, cocaine, toxicity of local anesthetics (systemic toxicity, neural toxicity, allergic reactions)Recommended Reading Materials:– Chapter 17 of Clinical Anesthesia by Barash, Cullen, Stoelting, 5th edition. Local Anesthetics (Liu SS, Joseph RS), p 453-471. – Chapter 14 of Miller’s Anesthesia, 6th edition - Local Anesthetics (Charles B. Berde and Gary R. Strichartz) |
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Local Anesthetics IIIAdditives including epinephrine, alpha-2 agonists, neostigmine, opioids.Recommended Reading Materials:- McCartney CJ, Duggan E, Apatu E. Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med. 2007 Jul-Aug;32(4):330-8. - Bernards CM.Understanding the physiology and pharmacology of epidural and intrathecal opioids. Best Pract Res Clin Anaesthesiol. 2002 Dec;16(4):489-505. - Elia N, Culebras X, Mazza C, Schiffer E, Tramèr MR.Clonidine as an adjuvant to intrathecal local anesthetics for surgery: systematic review of randomized trials. Reg Anesth Pain Med. 2008 Mar-Apr;33(2):159-67. - Habib AS, Gan TJ. Use of neostigmine in the management of acute postoperative pain and labour pain: a review. CNS drugs 2006; 20 (10): 821-39. |
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Spinal, Epidural and Caudal AnesthesiaAnatomy, physiology, pharmacology, clinical conduct including indications, contraindications, technical aspects, complications and management of complications for central neuraxial blockade.Recommended Reading Materials:- Chapter 25 of Clinical Anesthesia by Barash, Cullen, Stoelting, 5th edition. Epidural and Spinal Anesthesia (Bernards CM) p 691-717 - Chapter 43 of Miller’s Anesthesia, 6th edition. Spinal, Epidural, and Caudal Anesthesia (David L. Brown) |
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Peripheral Nerve Blockade:Anatomy, pharmacology, clinical conduct including indications, contraindications, technical aspects, complications and management of complications for peripheral neural blockade.Recommended Reading Materials:- Chapter 26 of Clinical Anesthesia by Barash, Cullen, Stoelting, 5th edition. Peripheral Nerve Blockade (Mulroy MM), p 718-745. - Chapter 44 of Miller’s Anesthesia, 6th edition. Nerve Blocks (Denise J. Wedel and Terese T. Horlocker) |