Contact information:  Peter Tarczy-Hornoch MD, FACMI University of Washington  Department of Biomedical Informatics and Medical Education Department of Pediatrics (Neonatology) Department of Computer Science and Engineering Box 357240 Seattle WA 98195-7240  EMAIL: pth@uw.edu LinkedIn: Profile Page Updated Jul 6 2020

• Professor and Chair, Department of Biomedical Informatics and Medical Education
  
• Division Head, Division of Biomedical and Health Informatics
• Professor, Department of Pediatrics, Division of Neonatology, 
• Adjunct Professor, Department of Computer Science and Engineering

• Director, Precision Medicine Informatics Group (PMIG): Projects include phenotype extraction from electronic medical record data; genomic biospecimen acquisition; integration of genomic data into electronic medical records for genetic medicine.
• Senior Informatics Advisor, Biomedical Informatics Core, Institute of Translational Health Sciences (funded by NIH Clinical Translational Science Award - CTSA)
• UW Medicine Clinical Research Informatics Committee
  
• UW Medicine Information Technology Oversight Committee
• UW Medicine Information Technology Service Executive Leadership
• UW Medicine Executive Data and Analytics Governance Committee
  
• Deputy Graduate Program Director, Graduate Program in Biomedical and Health Informatics
• Program Director/PI, UW Biomedical and Health Informatics Research Training Program (funded by the NIH NLM)
• Diversity, Equity and Inclusion Committee, Department of Biomedical Informatics and Medical Education
  

• External Advisory Committee, Utah Center for Clinical and Translational Sciences (CTSA)
• External Scientific Panel, ClinGen  ("dedicated to building a central resource that defines the clinical relevance of genes and variants for use in precision medicine and research")
• External Advisory Committee, CTSA Center for Leading Innovation and Collaboration (CLIC)
• Elections Commitee, American College of Medical Informatics
  
• Chair Elect (2019-20), Chair (2021-22), Past Chair (2023-24), AMIA Academic Leaders Community (ALC).
  

• Biomedical Informatics Core of the Institute of Translational Health Sciences
  
• [NIH CTSA, Semopr Informatics Advisor,  Biomedical Informatics Core]
  
• Informatics Goal: We propose to build the NW Clinical Research Informatics Collaborative, which will be a single, shared resource that that offers existing and newly developed clinical research informatics tools and services to address needs of our users. This resource will rely on a central web portal, central help desk, and a shared set of tools that we will develop. We will also partner with the University of Washington Health Sciences Library to create a strong support environment for informatics tools at our hub.
  
• Evolving our Partnership: The CSER2 Centralized Support Coordinating Center
• [NIH NHGRI, Jarvik, Veenstra, Nickerson, Fullerton, Tarczy-Hornoch (MPI)]
• Our overall goal in this coordinating center proposal is to enhance the effectiveness of Clinical Sequencing Exploratory Research (CSER) Consortium studies by assuring effective coordination and logistic support, moving cross-consortium work forward, identifying synergies that increase the scientific value of the individual projects, and leading outcomes efforts.
  
• Customizing Value-based Methods to Prioritize Implementation of Pharmacogenomic Clinical Decision Support for Learning Health Systems
• [AHRQ, Devine PI, Tarczy-Hornoch Significant Contributor]
• Pharmacogenomics (PGx) is well-positioned to be the first genomics application to realize the promise of precision medicine. Active PGx clinical decision support (PGx-CDS) alerts are proposed as one preferred method for returning PGx test results; the value of providing PGx-CDS alerts has not been formally evaluated. We will create a framework (Aim 1) and publically available web-based tool (Aim 2) to assist Learning Health Systems in investing in PGx-CDSalerts of greatest value to their specific population.
  
• Graduate Program in Biomedical and Health Informatics
• [NIH NLM, Tarczy-Hornoch PI]
• The Biomedical and Health Informatics (BHI) training program  at the University of Washington has been designed based on the principle that a key characteristic of successful BHI researchers is the ability to play a leadership role in translating and advancing methods and models from the computing sciences, information sciences and behavioral sciences into tools and solutions for information-related challenges and opportunities faced by care providers, patients and their families, biomedical researchers, and public health providers. This training grant supports stipend and tuition benefits for both pre-doctoral and postdoctoral trainees in the field of Biomedical and Health Informatics.
  

• Mentorship History: 5 undergraduates, 2 medical students, 18 MS students, 22 PhD students, 32 postdocs, 6 faculty
• Director, Clinical Informatics Fellowship "Enterprise Rotation" (locally developed applications, analytics, security)bi
  
• MEBI 530 Introduction to Biomedical and Health Informatics (Fall) (Past Course Chair)
  
• MEBI 590 Biomedical and Health Informatics Lecture Series (Fall, Winter, Spring) (Past Course Chair)
  
• HuBio 590 Medical Information for Decision Making (Fall) (Past Course Chair)

• PubMed search for Tarczy-Hornoch P
• Associate Editor for Translational Bioinformatics, Editorial Board, Journal of Biomedical Informatics and Journal of Biomedical Informatics X (JBIX)
  
• Associate Editor for Biomedical Informatics, Editorial Board, Genetics in Medicine
  

• Clinical Informatics Advisory Committee, University of Washington Academic Medical Centers
• Clinical Computing Steering Committee, University of Washington Academic Medical Centers
• Chief, Research and Data Integration, UW Medicine Information Technology Services
• Associate Director and Director of Biomedical Informatics Core, Northwest Institute of Genetic Medicine (funded by The Life Sciences Discovery Fund)
• Attending Staff, University of Washington Medical Center, Seattle WA
• Attending Staff, Seattle Children's Hospital, Seattle WA

Selected Prior National Positions

• External Advisory Committe, Gene Ontology
  
• External Advisory Committee, Informatics for Integrating Biology and the Bedside (i2b2)
• External Advisory Committee, integrating Data for Analysis, Anonymization and SHaring (iDASH)
• OSMB, Data Fusion: A Sustainable, Scalable, Open Source Registry Advancing PVD Research
• 
  
• Co-Chair Scientific Program Committee, Chair of Foundations Track, AMIA Fall Symposium (2005)
• Chair, Scientific Program Committee, AMIA Summit on Translational Bioinformatics (2010)
• Chair, 9th AMIA Policy Invitational (2014) “Harnessing Next-Generation Informatics for Personalizing Medicine”
• 
  
• Chair  AMIA Genomics Working Group (now AMIA Genomics and Translational Bioinformatics Working Group)
  
• Co-Chair, IMIA Informatics in Genomic Medicine Working Group
  
• Chair, NHGRI Clinical Sequencing Exploratory Research Electronic Medical Records Working Group
  
• Co-Chair (2017-19), Informatics Domain Task Force Lead Team for national CTSA consortium
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• Editorial Board, Journal of the American Medical Informatics Association

Prior Informatics Projects

• Data Integration
  •  BioMediator: A biological data integration and analysis system for cross database queries ("keeping up to date")[NIH, PI]
  • Uncertainty in Information Integration: Incorporating uncertainty about sources, links, and results into a biological data integration system [NSF, co-PI along with Alon Halevy and Dan Suciu of Computer Science and Engineering)
  • "Adapting the i2b2 architecture to support cross institutional clinical translational research" (CICTR) [Co-Investigator]
  • See below IAIMS Grant MINDscape also
  • "Surgical Care and Outcomes Assessment Program (SCOAP) Comparative Effectiveness Research Translation Network (CERTN)" [Co-Investigator, Lead of the Health Informatics Core]
  • The focus of the health informatics core of this research project is to link and validate automated collection of data needed for surgical comparative effectiveness research across multiple different hospitals and other organizations
• Genetic database grants
  • GeneTests: A database of laboratories and genetic tests (the "yellow pages")[co-PI, Informatics Architect]
  • GeneReviews: (formerly GeneClinics) A knowledge base of medical genetics (the "user's manual")[co-PI, Informatics Architect]
  • Biomedical Informatics Core of the Northwest Institute of Genetic Medicine
    
  • [LSDF, Director of the Biomedical Informatics Core]
  • Extracting phenotype from the electronic medical record
  • Pharmacogenomic decision support in electronic health records
  • Clinical Sequencing in Cancer: Clinical, Ethical and Technological Studies
  • [NIH NHGRI CSER, Jarvik PI, Tarczy-Hornoch Co-Investigator]
  • The focus of the biomedical informatics work is to incorporate results from whole exome sequencing on consented patients into the production electronic medical record for both passive and active decision support
  • Biospecimen Acquisition [WA LSDF, Biomedical Informatics Lead]
  • Consortium Biospecimen Program (Porter PI)
  • Washington Phenotyped Biospecimen Resource (Slattery PI)
  • The focus of the informatics work is to develop systems to aid in biospecimen acquisition for research studies from consented/assented patients
• Clinical Systems
• MINDscape (integrated web interface to clinical information) [IAIMS grant, Clinical Informatics Lead]
          About MINDscape: Integrating Access to Clinical Information Via the Web
• Detecting Errors in Blood Labs Using Bayesian Networks [Subcontract PI, PI: Jason Doctor at USC]
  
• Planning Grant for National Center of Excellence in Biomedical Computing [co-PI, co-Director]
• Development projects:
  Project 1: Develop generalizable anatomical structure based methods for representing and managing biological information (Lead: Brinkley)
  Project 2: Develop methods and tools for ontology alignment, whereby ontologies are linked by a set of explicit mapping relations that provide coherent semantics across multiple ontologies and their data (Lead: Gennari)
  Project 3: Develop a peer data management system (Bio-PDMS) and toolkit for sharing of heterogeneous biological data from diverse existing data sources leveraging new and existing ontologies (Lead: Tarczy-Hornoch)
• Telemedicine grants[Clinical Director]
• From Bench to Bedside and Beyond: Building and Testing an Integrated Regional Medical Information Network for the Pacific Northwest
• Washington, Wyoming, Alaska, Montana, and Idaho Rural Telemedicine Network
  
• Neonatology Informatics Projects [Supervisor]
  
  • University of Washington neonatal QA database
  • University of Washington Neonatology web site: NICU-WEB
  • PDA based client/server NICU patient data and charting system
    • Fall 2001 AMIA paper on the development of the system
    • Fall 2002 AMIA paper on the implementation and deployment of the system
  • Electronic mailing list server for neonatologists: NICU-NET