Philip J. Mease, M.D.  

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Curriculum Vitae August 2001

Personal Data

Birthplace Roanoke, Virginia Married, two children
Birthdate October 4, 1951  
Office Address Seattle Rheumatology Associates
1101 Madison Street, Suite 230
Seattle, WA 98104
Swedish Hospital Clinical Research Center
1120 Cherry
Seattle, WA 98104
Phone (206) 386-2000  
Fax (206) 386-2083  
Email pmease@u.washington.edu  
Internet http://faculty.washington.edu/pmease  

Education

1973-1977 MD Stanford University Medical School, Stanford, California
1969-1973 BA Stanford University, Stanford, California
1967-1969 Phillips Exeter Academy, Exeter, New Hampshire

Training

1981-1982 Senior Fellow, Department of Internal Medicine, Division of Rheumatology and Division of Geriatrics, University of Washington, Seattle, WA
1980-1981 Chief Resident, Department of Medicine, University of Washington, Seattle, WA Senior Fellow, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA
1979-1980 Senior Resident, Department of Internal Medicine, University of Washington, School of Medicine, Seattle, WA
1978-1979 Junior Resident, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA
1977-1978 Intern, Department of Internal Medicine, University of Washington School of Medicine, Seattle, WA

Professional Experience

5/01-Present Rheumatology and Internal Medicine, Seattle Rheumatology Associates, Seattle, WA
5/01-Present Investigator, Swedish Hospital Clinical Research Division, Seattle, WA
1985-5/01 Rheumatology and Internal Medicine, Minor & James Medical, Seattle WA
1996-12/00 Medical Director, Division of Clinical Research, Minor & James Medical, Seattle WA
1989-Present Medical/Research Consultant, Center for Comprehensive Care, Seattle, WA
1995-12/01 Medical/Research Consultant, Osteoporosis and Bone Health Center, Minor & James Medical,
Seattle, WA
1982-Present Clinical Professor, University of Washington, Seattle, WA
1994-Present Consultant, Clinical Development, MyoRx/EBOC Corporation
1997-Present Consultant, Clinical Development, Histatek Corporation
1999-Present Consultant, Clinical Development, Aventis Pharmaceuticals
1999-Present Consultant, Clinical Development, Centocor
2000-Present Consultant, Clinical Development, Immunex
2000-Present Consultant, Clinical Development, Zymogenetics
2001-Present Consultant, Clinical Development, Targeted Genetics
2001-Present Consultant, Clinical Development, Pharmacia
2001-Present Consultant, Clinical Development, Zorion
2001-Present Consultant, Clinical Development, Cypress Bioscience
1983-1985 Attending Physician, Providence Medical Center, Arthritis Center, Seattle, WA
1982-1985 Private Practice, Rheumatology and Internal Medicine, Seattle, WA

Board Certification

1982 American Board of Rheumatology
1980 American Board of Internal Medicine

Licensure To Practice

State of Washington License Number MD 00016710

Professional Organizations

1996 American Society of Bone & Mineral Research
1982 King County Medical Society
1982 American College of Rheumatology
1978 American College of Physicians

Hospital Appointments

Swedish Medical Center
Providence Medical Center

Teaching Activities

Teaching Physician, Family Practice and Internal Medicine Residence Program, Swedish Medical Center, Seattle, WA
Teaching Physician, Family Practice and Internal Medicine Residence Program, Providence Medical Center, Seattle, WA
Clinical Professor, University of Washington Hospitals
Teaching Physician, Nurse Practitioner Program, Seattle University

Advisory Boards

2001-Present Immunex/Wyeth Ayerst, Psoriatic Arthritis and Psoriasis Advisory Board
2000-Present Pfizer, Fibromyalgia Advisory Board
1998-Present Proctor & Gamble/Hoechst Marion Roussel, Alliance for Better Bone Health, Northwest Regional Expert Consultant Board
1998-Present Proctor & Gamble/Hoechst Marion Roussel, Alliance for Better Bone Health, National Primary Care Consultant Panel
1998-Present Immunex/Wyeth Ayerst, Patient Compliance Advisory Board

Journal Review Boards

Journal of Rheumatology

Speaker's Bureaus

Arthritis Foundation, Lupus Foundation, Sjogren’s Society, National Psoriasis Foundation, Wyeth Ayerst, Immunex, Merck, Searle, Pfizer, Aventis, Ortho McNeil, SmithKline Beecham, Genelab Technologies, Proctor & Gamble

Community Activities

1999-Present Director, Northwest Arthritis Institute (non-profit education and research foundation)
1997-Present Board, Lupus Foundation, Washington State Chapter
1988-Present Medical Advisory Board, Lupus Foundation, Washington State Chapter
1994-1996 Professional Education Committee, Arthritis Foundation, Washington State Chapter
1990-1996 Coach, Seattle Youth Soccer Association
1989-1993 Executive Committee, Arthritis Foundation, Washington State Chapter
1989-1993 Chair, Education Committee, Arthritis Foundation , Washington State Chapter
1989-1993 Board, Arthritis Foundation, Washington State Chapter

Honors & Awards

2000 Recognized in The Best Doctors in Western Washington
2000 Lifetime Member, National Registry of Who’s Who
1993 Medical Communicator Award of the American College of Rheumatology
Awarded annually to the physician who most effectively and dynamically presents Rheumatology subjects to the public.
1992 Recognized in The Best Doctors in America
1992 Recognized in The Best Doctors in Western Washington

Bibliography

Book Chapters

Mease PJ: Rheumatologic Issues. in Agostini R (ed.) Medical and Orthopedic Issues of Active and Athletic Women. Hanley & Belfus, Philadelphia 1994.

Mease PJ: Culture variations in health care. Transcultural Study Guide, Volunteers in Asia Press, 1973.

Journal Articles

Mease PJ, Ochs HD, Wedgewood RJ: Successful treatment of ECHO-virus meningoencephalitis and myositis- fasciitis with intravenous immune globulin therapy in a patient with X-linked agammaglobulinemia. New Engl J Med 304: 1278-1281, 1981.

Fretwell MD, Pearlman RA, Vestal RE, Mease PJ, Hazard WR: Fever and delirium in three elderly patients. A discussion of possible cimetidine toxicity, cimetidine pharmacology, and the application of decision analysis to cimetidine therapy. Medical Grand Rounds 1:223-238, 1982.

Mease PJ, Ellsworth JG, Killen PD, Willkens RF: Zomepirac, Interstitial Nephritis, and Renal Failure. Ann Int Med 97:454, 1982.

Mease PJ, Willkens RF: Treatment of Acute Gout with Oxaprozin. Sem Arth Rheum 15 (Suppl 2): 86-89, 1986.

Culpepper RC, Williams RG, Mease PJ, et al. Eosinophilia Myalgia Syndrome: Investigation of Washington Cases. Wash Pub Health 16-18, Winter 1991.

Culpepper RC, Williams RG, Mease PJ, et al. Natural History of the Eosinophilia Myalgia Syndrome. Ann Int Med 115: 437-442, 1991.

Katon WJ, Buchwald DJ, Simon GE, Russo JE, Mease PJ: Psychiatric Illness in patients with chronic fatigue and those with rheumatoid arthritis. J Gen Int Med 6:227-285, 1991.

Buchwald DJ, Blair J, Mease PJ: Treatment of Chronic Fatigue Syndrome with Acupuncture. Intl J Clinical Acupuncture 2: 231-236, 1991.

Hertzman P, Kaufman L, Love L, Mease P, et al. Eosinophilia Myalgia Syndrome: Guidelines for Patient Care. J Rheum 22: 161-163, 1995.

Hertzman P, Clauw D, Kaufman L, Vargas J, Silver R, Thacker H, Mease P, Espinoza L, Pincus T: The Eosinophilia-Myalgia Syndrome: Status of 205 Patients and Results of Treatment 2 Years after Onset. Ann Intern Med 1995;122:851-855.

Wolfe F, Allen M, Bennett RM, Bombardier C, Mease P, et al. The Fibromyalgia Syndrome: A Consensus Report on Fibromyalgia and Disability. J Rheum 1996;23:534-539.

Moreland LW, . . . Mease PJ, et al. Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann. Internal Medicine 130:478-486, 1999

Moreland LW, . . . Mease PJ, et al. Long-term treatment of rheumatoid arthritis with Etanercept (Tumor Necrosis Factor Receptor p75 Fc Fusion Protein, ENbrEL™). Lancet, 1999.

Mease PJ, Goffe B, Metz J, et al. Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomized trial. Lancet 356:385-390, 2000.

Mease PJ. Etanercept in the management of psoriatic arthritis and psoriasis. J of Musculoskeletal Medicine
Supplement, S45-S49 May 2001.

Mease PJ. Cytokine blockers in psoriatic arthritis. Annals of Rheumatic Disease, in press

Abstracts

Ochs HD, Mease PJ, Wedgwood RJ, Rischer SH: Generalized Echo-11virus infection in X-linked agammaglobulinemia: Successful treatment with large doses of modified gammaglobulin given intravenously.
Primary Immunodeficiencies, Seligmann, Hitig (editor). INSERUM Symposium No. 16, The Netherlands: Elsevier, North Holland Biomedical Press, 513-514, 1980.

Mease PJ, Ochs HD: Successful treatment of the dermatomyositis/meningoencephalitis syndrome in X-linked agammaglobulinemia with intravenous immune globulin. Clinical Research 29 (No.1): 92A, 1981.

Mease PJ, Ochs HD, Wedgewood RJ: Successful treatment of the dermatomyositis/meningoencephalitis syndrome in X-linked agammaglobulinemia with intravenous immune globulin. Clinical Research 29 (No. 2):
372A, 1981.

Mease PJ, Ochs HD, Wedgwood RJ: Successful treatment of the ECHO-virus induced dermatomyositis/meningoencephalitis syndrome in X-linked agammaglobulinemia with intravenous immune globulin. 15th International Congress of Rheumatology, Paris, France, June, 1981.

Bowden RA, Mease PJ: Human Herpes Virus 6 (HHV6) infection in a patient with undifferentiated autoimmune
disease; evidence for clinical infection? 28th ICAAC, Los Angeles, California, October 1988.

Culpepper RC, Williams RG, Mease PJ, et at. Eosinophilia Myalgia Syndrome (EMS): Epidemiologic
features, progression of disease, and therapeutic approaches. Arth Rheum 33(No. 9): 518, 1990.

Townes B, Mease P, Claypoole K, et al. Neurocognitive dysfunctioning in eosinophilia myalgia syndrome.
Arth Rheum 35 (No. 9) (Supplement): S67, 1992.

Blair J, Mease P, Buchwald D, et al. The use of acupuncture as an intervention in a fibromyalgia and chronic fatigue self-management program. J. Musculoskeletal Pain 3 (No. 1)(Supplement): 90, 1995.

Mease PJ, Driscoll P, Uslan D, et al. Multidisciplinary self-management and treatment program for patients with fibromyalgia and chronic fatigue syndrome. Arth Rheum 38 (No. 9)(Supplement): S271, 1995.

Mease PJ, Overman SS, Green DJ. Clinical symptoms/signs and laboratory features in symptomatic patients with silicone breast implants. Arth Rheum 38 (No. 9) (Supplement): S324, 1995.

Weinblatt M, Moreland LW, Schiff M,…Mease P, et al. Long-term and phase III treatment of DMARD failing rheumatoid arthritis patients with TNF receptor p75 Fc fusion protein (TNFR:Fc Enbrel™), Arth Rheum 1997;40 (Supp.9):S126

Baumgartner SW,…Mease P, et al. Phase III and longterm treatment of DMARD failing rheumatoid arthritis patients with TNF receptor p75 Fc fusion protein (TNFR:Fc). Rheumatology in Europe, 1997.

Moreland LW,…Mease PJ, et al. Long-term treatment of rheumatoid arthritis (RA) with p75 TNF receptor (TNFR:Fc; Enbrel). 19th International League of Associations for Rheumatology, 1997.

Schiff MH, Moreland LW, Baumgartner SW,…Mease P, et al. Quality of life (QOL) and laboratory measures in a phase III trial of TNF-receptor (p75):Fc fusion protein (TNFR:Fc; Enbrel™) in DMARD failing rheumatoid arthritis. Intl Soc Rheum Therapy, 1998.

Schiff MH, Moreland LW, Baumgartner SW,…Mease P, et al. TNF receptor (p75):Fc Fusion Protein (TNFR:Fc: Enbrel™) results in improvement in clinical laboratory parameters in patients with rheumatoid arthritis (RA). Intl Soc Rheum Therapy, 1998.

Ehrich E, … Mease P, et al. The effect of MK-0966 (Vioxx™), a cox-2 specific inhibitor, on health related quality of life in osteoarthritis patients. EULAR, 1998..

Baumgartner SW,… Mease PJ, et al. Response of elderly patients to TNF receptor p75 FC fusion protein TNFR:Fc; Enbrel™). Arth Rheum 41 (Supp. 9): 559, 1998.

Moreland LW, … Mease PJ, et al. Optimal dose of TNF receptor p75 FC fusion protein (TNFR:Fc; Enbrel™).
Arth Rheum 41 (Supp. 9): 559, 1998.

Moreland LW, … Mease PJ, et al. Long term safety and efficacy of TNF receptor (p75) Fc fusion protein (TNFR:Fc; Enbrel™) in DMARD refractory rheumatoid arthritis (RA). Arth Rheum 41 (Supp. 9): S364. 1998.

Moreland LW,… Mease PJ, et al. Long-term treatment of rheumatoid arthritis (RA) with TNF receptor p75 Fc fusion protein (TNFR:Fc; Enbrel™). J Investig Med, 1998.

Moreland LW,…Mease PJ, et al. Long-term treatment of DMARD failing rheumatoid arthritis patients with TNF receptor p75 Fc fusion protein (TNFR:Fc; Enbrel). EULAR, 1998.

Moreland LW,…Mease PJ, et al. Phase III trial of DMARD failing rheumatoid arthritis patients with TNF receptor p75 fusion protein (TNFR:Fc; Enbrel). J Investig Med, 1998.

Moreland LW,…Mease PJ, et al. Phase III trial of DMARD failing rheumatoid arthritis patients with TNF receptor fusion protein (TNFR:Fc; Enbrel). EULAR, 1998.

Moreland LW,…Mease PJ, et al. Long-term safety and efficacy of TNF receptor (p75) Fc fusion protein (TNFR:Fc; Enbrel) in DMARD refractory rheumatoid arthritis (RA). Ann Rheum Dis, 1998.

Mease PJ, Goffe B, Metz J, Vanderstoep A. Etanercept in patients with psoriatic arthritis and psoriasis. Arth Rheum 42 (Supp.), 1999.

Mease PJ, Goffe B, Metz J, Vanderstoep A. Phase II trial of Enbrel (Etanercept) in patients with psoriasis and psoriatic arthritis (PsA). American Academy of Allergy Asthma & Immunology, 2000.

Mease PJ, Goffe B, Metz J, Vanderstoep A. Etanercept in patients with psoriatic arthritis and psoriasis. American Academy of Dermatology, San Francisco, CA. 3/00.

Mease PJ, Merrill J, Lahita R, et al. GL701 (Dehydroepiandrosterone) improves or stabilizes disease activity in systemic lupus erythematosus. Autoimmunity: 2000 and Beyond. Eighth International Conference on Lymphocyte Activation and Immune Regulation, Newport Beach, CA, 2/00.

Mease PJ, Merrill J, Lahita R, et al. GL701 (Prasterone, Dehydroepiandrosterone) improves or stabilizes disease activity in systemic lupus erytematosus. Endocrine Society, 2000.

Mease PJ, Ginzler EM, Gluck OS. GL701 (prasterone, dehydroepiandrosterone) improves bone density in steroid-treated female lupus patients. Am Soc Bone Min Research, 2000.

Mease PJ, Goffe B, Metz J, et al. Enbrel (Etanercept) in patients with psoriatic arthritis and psoriasis. Arth Rheum 43 (Suppl 9):S403, 2000.

Mease PJ, Merrill JT, Lahita RG, et al. GL701 (Prasterone, Dehydroepiandrosterone) improves systemic lupus erythematosus. Arth Rheum 43 (Suppl 9):S271, 2000.

Mease PJ, Ginzler EM, Gluck OS, et al. Improvement in bone mineral density in steroid-treated SLE patients during treatment with GL701 (Prasterone, Dehydroepiandrosterone). Arth Rheum 43 (Suppl 9):S206, 2000.

Fraser PA, …Mease PJ, et al. TNF alpha-308 rather than HLA-DRB1 alleles are markers of early response to etanercept in Still’s disease in the adult. Arth Rheum 43 (Suppl 9):S228, 2000.

Weinblatt ME, …Mease PJ, et al. Etanercept in Still’s disease in the adult. Arth Rheum 43 (Suppl 9):S391, 2000.

Schiff M, Mease PJ, Weinblatt M, et al. Randomized controlled trial of 25 Mg vs. 50 Mg Enbrel (Etanercept) twice weekly in rheumatoid arthritis (RA). Arth Rheum 43 (Suppl 9):S391, 2000.

Mease PJ, Goffe B, Metz J, et al. Etanercept in patients with psoriatic arthritis and psoriasis. American Academy of
Dermatology, 55th Annual Meeting. Washington, DC. 3/2-7/01.

Mease PJ, Gofe B, Metz J, et al. Etanercept in patients with psoriatic arthritis and psoriasis. EULAR, Prague, 6/01.

Mease PJ, Goffe B, Metz J, et al. Etanercept in patients with psoriatic arthritis and psoriasis. International Symposium on Psoriasis and European Congress on Psoriasis. San Francisco, CA 6/01.

Mease PJ, Goffe B, Metz J, et. al. Etanercept in patients with psoriatic arthritis and psoriasis. In Year Book of Rheumatology, Arthritis, and Musculoskeletal Disease, ed. Panush R, Mosby-Year Book, St. Louis, in press.

Mease PJ, Goffe B, Metz J, et. al. Etanercept in patients with psoriatic arthritis and psoriasis. In Year Book of Dermatology, Mosby-Year Book, St. Louis, in press.

Newsletters & Periodical Articles

1998-Present Quarterly Q & A column, Lupus Foundation Newsletter, Washington State Chapter.
1995 DHEA and Lupus, Newsletter of the American Lupus Society - Seattle/Bellevue Chapter.
1996 Rheumatological Disorders Associated with Celiac Sprue and Dermatitis Herpetiformis. Newsletter of the Gluten Intolerance Group of North America.

Research Activities

2001
- IL-1 modulator in RA (Principal Investigator) (Immunex)
- Raloxifene v. Alendronate in osteoporosis (Principal Investigator) (Lilly)
- Enbrel in psoriatic arthritis and psoriasis (Principal Investigator/protocol development) (Immunex)
- Remicade in RA - the iRAMT trial (Principal Investigator) (Centocor)
- Duloxitene in fibromyalgia (Principal Investigator) (Lilly)
- Enbrel in RA - longterm safety and efficacy (Principal Investigator) (Immunex)
- Choices - osteoporosis patient education research (Prinicipal Investigator) (Procter&Gamble/Aventis)
- Rheumatoid joint tissue sampling for genetic therapy development (Principal Investigator) (Targeted Genetics)
- RA, Lupus, Psoriasis patient blood sampling for drug development (Principal Investigator) (Zymogenetics)
2000
- IL1RA +/- Enbrel in rheumatoid arthritis (Principal Investigator) (Amgen)
- Anti- DNA antibody treatment in lupus nephritis (Principal Investigator) (La Jolla Pharmaceuticals)
- Psoriais skin transplantation to SCID mice (Principal Investigator/protocol development) (Zymogenetics)
- PTH in osteoporosis (Principal Investigator) (Allelix)
- Pregabalin in diabetic neuropathy (Principal Investigator) (Pfizer)
- Enbrel in psoriatic arthritis and psoriasis (Principal Investigator/protocol development) (Immunex)
- Enbrel in RA with co- morbid diseases (Principal Investigator) (Immunex)
- Remicade in RA (Principal Investigator) (Centocor)
- Anti- TNF (pegylated) in RA (Sub- Investigator) (Amgen)
- Insulin growth factor 1 in OA (Principal Investigator) (Chiron)
- Prosorba column in RA (Sub- Investigator) (Cypress Bioscience)
- Lupus patient blood sampling (Principal Investigator) (Cellpath)
- Autoimmune disease patient blood sampling (Principal Investigator/protocol development) (Zymogenetics)
- Enbrel in RA - long term safety and efficacy (Principal Investigator) (Immunex)
- Valdecoxib in OA and RA (Principal Investigator) (Searle)
- Pregabalin in Fibromyalgia (Principal Investigator) (Parke- Davis)
- Vioxx in RA (Principal Investigator) (Merck)
1999
- Enbrel™ in psoriatic arthritis and psoriasis (Principal Investigator/protocol development/FDA submission with Immunex support)
- Enbrel in RA: 25 vs. 50 mg dosing (Principal Investigator) (Immunex)
- Anti-TNF (pegylated) in RA (Sub-Investigator) (Amgen)
- Risedronate - weekly vs. daily dosing in Osteoporosis (Principal Investigator) (P&G/HMR)
- Pregabalin in Fibromyalgia (Principal Investigator) (Parke-Davis)
- Valdecoxib in OA and RA (Principal Investigator) (Searle)
- Celebrex (Cox-2 NSAID) Gastrotoxicity (OA/RA) (Principal Investigator) (Searle)
- D2E7(anti-TNF)in RA (Sub-Investigator) (Knoll) - DHEA in Lupus (Principal Investigator) (Genelabs)
- Parathyroid Hormone in Osteoporosis (Principal Investigator) (Lilly)
- Idoxifene in Postmenopausal Women with Vasomotor Symptoms (Principal Investigator) (SmithKline Beecham)
- Idoxifene in Osteoporotic and Osteopenic Women (Principal Investigator) (SmithKline Beecham)
- Anti-TNF in RA (Sub-Investigator) (Roche)
- Enbrel in RA (Principal Investigator) (Immunex)
- UCLA RA Treatment Outcome Study
- NSAID Gastrotoxicity (Principal Investigator) (Searle)
- Vioxx in OA/RA (Sub-Investigator) (Merck)
- Colloral in RA (Principal Investigator) (Autoimmune)
- Bay 12-9566 (metalloproteinase inhibitor) in OA (Principal Investigator) (Bayer)
1998

-Enbrel™ in psoriatic arthritis and psoriasis (Principal Investigator/protocol development/FDA submission with Immunex support)
- Celebrex (COX-2 NSAID) Gastrotoxicity (OA/RA) (Principal Investigator) (Searle)
- D2E7 anti-TNF DMARD in RA (Sub-Investigator) (Knoll)
- RA Therapeutic Vaccine (Principal Investigator) (Anergen)
- TAK-603 in RA (Principal Investigator) (TAP)
- SN-2011 in Sjogren’s Syndrome (Principal Investigator) (Snow Brand)
- DHEA in Lupus (Principal Investigator) (Genelabs)
- Parathyroid Hormone in Osteoporosis (Principal Investigator) (Lilly)
- Idoxifene in Postmenopausal Women with Vasomotor Symptoms (Principal Investigator) (SmithKline Beecham)
- Idoxifene in Osteoporotic and Osteopenic Women (Principal Investigator) (SmithKline Beecham)
- TNF in RA (Sub-Investigator) (Roche)
- Enbrel in RA (Principal Investigator) (Immunex)
- UCLA RA Treatment Outcome Study
- NSAID Gastrotoxicity (Principal Investigator) (Searle)
- Vioxx in OA/RA (Sub-Investigator) (Merck)
- Colloral in RA (Principal Investigator) (Autoimmune)
- Bay 12-9566 (metalloproteinase inhibitor) in OA (Principal Investigator) (Bayer)

1997

- DHEA in Lupus (Principal Investigator) (Genelabs)
- Parathyroid Hormone in Osteoporosis (Principal Investigator) (Lilly)
- Idoxifene in Postmenopausal Women with Vasomotor Symptoms (Principal Investigator) (SmithKline Beecham)
- Idoxifene in Osteoporotic and Osteopenic Women (Principal Investigator) (SmithKline Beecham)
- TNF in RA (Sub-Investigator) (Roche)
- Enbrel in RA (Principal Investigator) (Immunex)
- UCLA RA Treatment Outcome Study
- NSAID Gastrotoxicity (Principal Investigator) (Searle)
- Anti-CD4 in RA (Sub-Investigator) (SmithKline Beecham)

1996

- TNFR in RA (Principal Investigator) (Immunex)
- DHEA in Lupus (Principal Investigator) (Genelabs)
- Cox-2 Anti-inflammatory in OA (Principal Investigator) (Merck)
- Idoxifene for Vasomotor Symptoms (Principal Investigator) (SmithKline Beecham)
- Anti-CD4 in RA (Sub-Investigator) (SmithKline Beecham)
- TNF in RA (Sub-Investigator) (Roche)
- UCLA RA Treatment Outcome Study

1995

- Cox-2 Anti-inflammatory (Principal Investigator) (Merck)
- DHEA in Lupus (Principal Investigator) (Genelabs)
- sTNFR-IgG in RA (Co-principal investigator) (Hoffmann-LaRoche)
- Piroxicam B-cyclodextrin vs. Piroxicam in OA (Principal Investigator) (Pfizer)
- Silicone-related rheumatic disorders, Fibromyalgia/CFS
- Fibromyalgia/CFS

1994

- sTNFR-IgG in RA (Roche)
- Deflazacort in RA (Marion Merrell-Dow)
- Silicone related rheumatic disorders
- Fibromyalgia/CFS
- H2B342 Ranitidine Bismuth Citrate Prophylaxis of NSAID-induced GU/DU (Glaxo)

1992-1993

- Silicone related disorders
- Eosinophilia Myalgia Syndrome (EMS)
- Fibromyalgia/CFS

1989-1991

- Eosinophilia Myalgia Syndrome (EMS)
- Fibromyalgia/CFS

Invited Presentations & Symposia

2001
-“Osteoporosis” - Physician CE, Seattle, WA
-“Osteoporosis - Current Diagnosis and Treatment” Physician CE, Kirkland, WA
-“Osteoporosis” Physician CE, Seattle, WA
-“Cytokine blockers in Psoriatic Arthritis” Targeted Therapies Symposium, Nassau, Bahamas
-“Arthritis” Community Education Symposium, Swedish Hospital, Seattle, WA
-“Osteoporosis for gastroenterologists” Gastroenterology symposium, Everett, WA
-“Anti-TNF Therapy in the Treatment of Psoriatic Arthritis, Psoriasis, Ankylosing Spondylitis, Wegener’s Granulomatosis, and CHF” Rheumatology Rounds, Yale University, New Haven, Conn
-Ibid, Rheumatology Rounds, University of Connecticut
-Ibid, Targeted Genetics, Seattle, WA
-“So you have a touch of… Management Approach to Difficult-to-Define Rheumatic Disease Presentations” Family
Practice Day, Swedish Hospital, Seattle, WA
-“Psoriatic Arthritis and Psoriasis - Current Review of Treatment Options” Grand Rounds, St. Vincent Hospital, Portland, Oregon
-“Enbrel in the Treatment of Non-RA Rheumatic Diseases” Rheumatology Symposium, Spokane, WA
-“Osteoporosis - Update on Diagnosis and Treatment” Grand Rounds, Allenmore Hospital, Tacoma, WA
2000
-“Etanercept in the Treatment of Psoriatic Arthritis and Psoriasis - A Clinical Update”, Post-ACR CME Symposium
Philadelphis, Pennsylvania
-“Osteoporosis in the US and in Washington State; Case Study Review”, Medical Consultant Review, Seattle, WA
-“New Developments in the Clinical Use of COX-2 Inhibitors”, Medical Consultant Review, Seattle, WA
-“New Developments in Rheumatic Disease Pharmacotherapy”, Rheumatology Symposium, Seattle, WA
-“Newer Uses of Enbrel in Rheumatic Diseases”, Houston Rheumatology Association, Houston, Texas
-Ibid, Virginia Rheumatology Association, Norfolk, Virginia
-Ibid, Las Vegas Rheumatology Association, Las Vegas, Nevada
-“Enbrel in the Treatment of Psoriatic Arthritis and Psoriasis”, Dermatology Rounds, OHSU, Portland, Oregon
- Ibid, Greater Chicago Rheumatology Association, Chicago, Illinois
- Ibid, Rush-Presbyterian Rheumatology/Dermatology Rounds, Chicago, Illinois
-Ibid, Kaiser-Permanente Rheumatology Group, Los Angeles, California
-“New Developments in the Treatment of Osteoporosis”, Physician CE, Chuckanut, WA
-“Arthritis and the COX2 InhibitorsWhat Have We Learned to Date?”, Physician CE, Federal Way, WA
-“Osteoporosis, Lupus, Antiphospholipid Antibody Syndrome” Family Practice Program, Swedish Hospital, Seattle
-“Enbrel in the Treatment of Psoriatic Arthritis, Psoriasis, Wegener’s Granulomatosis, and Early RA” Northern California Rheumatology Association, San Mateo, CA.
- “New Developments in the Diagnosis and Treatment of Osteoporosis”, Physician CE, Seattle, WA.
- Ibid, Physician CE, Kirkland, WA.
- “Psoriatic Arthritis” National Psoriasis Foundation Symposium, Seattle, WA.
-“Enbrel in the Treatment of Psoriatic Arthritis and Psoriasis” Rheumatology CE, Sacramento , CA.
- Ibid. EULAR symposium, Nice, France.
- Ibid. Rheumatology CE, Phoenix, Ariz.
- Ibid. Medical Grand Rounds, Maricopa County Hospital, Phoenix, Ariz.
- Ibid. Medical Grand Rounds, Beth Israel Hospital, NY, NY.
- Ibid. Rheumatology CE, Cabrini Hospital, NY, NY.
- Ibid. Rheumatology CE, Columbia University Medical Center, NY, NY.
- Ibid. Rheumatology CE, Montefiore Medical Center, NY, NY.
- Ibid. Rheumatology CE, Brooklyn VA Hospital, NY, NY.
- Ibid. Rheumatology CE, Mt. Sinai Medical Center, NY, NY.
- Ibid. Rheumatology CE, NY, NY.
- Ibid. Rheumatology CE, Portland, Ore.
- Ibid. Immunex Regional Consultant Meeting, SF, CA.
- Ibid. Seattle Dermatology Academy, Seattle, WA.
- Ibid. Immunex Investigator Meeting, Orlando, Fla.
- “Joint assessment in psoriatic arthritis” Immunex Investigator Meeting, Orlando, Fla.
- “Arthritis” Community Education Program, Swedish Hospital, Seattle, WA.
- “Rheumatoid Arthritis and Lupus” Family Practice Education Program, Swedish Hospital, Seattle, WA.
-“Enbrel in the Treatment of Psoriatic Arthritis and Psoriasis” Rheumatology for Primary Care, Mt. Batchelor, Oregon.
- Ibid. Rheumatology CE, Georgetown University, Washington, D.C.
- Ibid. Rheumatology CE, Washington Hospital, Washington., D.C.
-“Treatment of Psoriatic Arthritis” National Teleconferences (series of 8) sponsored by the University of Wisconsin Medical School.
-“Enbrel in the Treatment of Psoriatic Arthritis and Psoriasis” Rheumatology CE, Tacoma, Wa.
-“Enbrel in the Treatment of Early RA, Psoriatic Arthritis and Psoriasis, and Long-Term Safety and Efficacy”
Rheumatology CE, Seattle, WA.
-“Enbrel in the Treatment of Psoriatic Arthritis and Psoriasis” Rheumatology CE, Denver, Colo.
- Ibid. Rheumatology CE, Colorado Springs, Colo.
- Ibid. Rheumatology CE, Dallas, Texas.
- Ibid. Rheumatology CE, Oklahoma City, Oklahoma.
-“Diagnosis and Treatment of Lupus” Community Education Program, Swedish Hospital, Seattle, WA.
1999
-“Use of Enbrel in Other Rheumatic Diseases” Immunex Faculty Briefing, Chicago, Ill.
-“Practical Approach to Treatment of Arthritis Pain in the Elderly” Geriatric Pain Symposium, Seattle, WA.
- “Clinical Use of Enbrel in Rheumatoid Arthritis” Immunex Masters of Rheumatology Program, Seattle, WA.
-“Safety and Efficacy of Enbrel in Rheumatoid Arthritis, Controlled and Long-term Trials” Immunex Regional Consultant Meeting, Newport Beach, CA.
- “Safety and Efficacy of Enbrel in Rheumatoid Arthritis, Controlled and Long-Term Trials” Immunex Regional
Consultant Meeting, Orlando, Florida.
-“What is Integrational Medicine?” Panel discussion. International Symposium on Integrational Medicine, Seattle, WA.
- “Development of a Multidisciplinary Program for the Treatment of Fibromyalgia” International Symposium on Integrational Medicine, Seattle, WA.
- “Advances in the Treatment of Osteoarthritis and Rheumatoid Arthritis.” Minor & James Medical, Seattle, WA.
- “New Developments in Rheumatic Disease Pharmacotherapy.” CME Family Practice Programs, Swedish Hospital Medical Center and Providence Hospital, Seattle, WA.
- “New Developments in Arthritis.” Community Education Program, Swedish Hospital Medical Center, Seattle, WA
- “Update in Rheumatic Disease Pharmacotherapy” Grand Rounds, Swedish Hospital, Seattle, WA.
- “New Developments in Pharmacotherapy of Arthritis and Rheumatic Disease.” Nurse Practitioner Association
Symposium. Northwest Hospital, Seattle, WA
1998
-“Update in Pharmacotherapy of Arthritis and Rheumatic Disease.” Grand Rounds, Swedish Hospital Medical Center, Seattle, WA
- “What is Lupus?” Community Education Program. Swedish Hospital Medical Center, Seattle, WA
- “Update in Rheumatic Disease Pharmacotherapy.” Physician CME , Seattle, WA
- “Update in Rheumatic Disease Pharmacotherapy.” Pierce County Pharmacists Association, Tacoma, WA.
- “Rheumatoid Arthritis and Lupus.” Family Practice Program, Swedish Hospital Medical Center, Seattle, WA
1997

- “Update on Trends in Pain Management-Current Approaches to the Treatment of Pain
in Rheumatic Diseases.” Regional Symposium, Seattle, WA
“Rheumatic Disease Pharmacotherapy.” Grand Rounds, Northwest Hospital, Seattle, WA
“Rheumatic Disease Pharmacotherapy.” Grand Rounds, Swedish Hospital Medical Center, Seattle, WA
“Resident Teaching ConferenceRheumatology.” Family Practice Program, Swedish Hospital Medical Center, Seattle, WA
“Osteoporosis.” Orthopedic Teaching Conference, Seattle, WA
Osteoporosis Expert Consultants Program. Seattle, WA
“Treatment of Fibromyalgia.” Sixth Annual Conference on Fibromyalgia, Seattle, WA

1996

- “Psoriatic Arthritis.” National Psoriasis Foundation Annual Meeting, Seattle, WA
“Rheumatic Disease Pharmacotherapy.” Washington Geriatrics Society, Seattle, WA
“Beyond the Traditional ModelReal Life Strategies for Dealing with Patients with Chronic Illness.” Fifth Annual Health Education Conference, Providence Hospital, Seattle, WA
- “Swedish Hospital Family Practice ProgramRheumatology.” Resident Teaching Conference, Seattle, WA
“Multidisciplinary Care of Chronic Rheumatic Disease.” National Acupuncture and Oriental Medicine Alliance, Seattle, WA
Symposium Planner, Moderator and Speaker Fifth Annual Conference on Fibromyalgia, Seattle, WA
-“Fibromyalgia Treatment.” Fifth Annual Conference on Fibromyalgia, Seattle, WA.
“Osteoporosis.” Medalia Health Care Lecture, Seattle, WA
“Osteoporosis.” Osteoporosis Expert Consultants Program, Seattle, WA
“Osteoporosis.” Merck Speakers Bureau, Seattle, WA
“Oh Them Moans and Bones-Update in Rheumatic Disease Pharmacotherapy.” Providence Hospital Symposium Planner, Moderator and Speaker, Providence Medical Center, Seattle, WA
-“New Practice ModelsIntegrating Patient Health Education in a Clinical SettingMultidisciplinary Treatment of Chronic Rheumatic Disease.” Seattle, WA
-“Osteoporosis.” Fifth Annual Health Education Conference, Providence Hospital, Seattle, WA
-“Osteoporosis.” Swedish Teaching Conference, Swedish Hospital Medical Center, Seattle, WA

1995

 - “Rheumatology.” Family Practice Residency Program, Providence Hospital, Seattle, WA.
- “Psychoneuroimmunology.” Grand Rounds, Providence Hospital Psychiatry Unit, Seattle, WA.
- “Update on the Treatment of Lupus.” American Lupus Society, Seattle/Bellevue Chapter, Seattle, WA
- “Algorithm for the Evaluation of Musculoskeletal Complaints.” Los Angeles, CA
- “Total Patient Management in Arthritis.” Searle, San Francisco, CA
- “Fibromyalgia.” CLE Lecture, Federal Attorney General’s Office, Seattle, WA
- “When Our Body Turns Against UsLupus and Other Autoimmune Diseases.” Evening Lecture Series, Swedish Hospital Medical Center, Seattle, WA
- Moderator and Organizer. Fifth Annual Symposium on Fibromyalgia, Chronic Fatigue, and Related Disorders, Seattle, WA
- “Riverton Hospital, A Practical Approach to the Patient with Chronic Aching and Fatigue.” CME Lecture, University of Washington, Seattle, WA
- “Practical Issues in Rheumatologic Diagnosis and TreatmentThe Mind - Body Connection.” CME Lecture, Seattle, WA
- “RheumatologyCase Studies.” Resident Teaching Conference Family Practice Program, Swedish Hospital Medical Center, Seattle, WA
- Silicone - Related Disorders Study Group. New Orleans, LA
- “Why Do We Do It.” Conference on Fibromyalgia and Management of Fibromyalgia Patients, Swedish Hospital Medical Center, Seattle, WA

1994

-“Fibromyalgia and Chronic Fatigue Syndrome.” Expert Consensus Conference, Physical Medicine
Foundation of Canada, Vancouver, British Columbia.
- “Rheumatology Care Presentations.” CME Lecture, St. Francis Hospital, Tacoma, WA
- “SLE.” Lupus Society, Providence Hospital, Seattle, WA
- Silicone Related Disorders Study Group. New Orleans, LA
- “Total Patient Management in ArthritisThe Role of Physical Therapy and Nutrition.” Searle, Orlando, FL
- “Injection Therapy in Arthritis.” Searle, San Francisco, CA
- “Anti-phospholipid Antibody Syndrome.” Universidad de Chile, Santiago, Chile
- “Anti-phospholipid Antibody Syndrome.” Universidad de la Frontera, Temuco, Chile
- “Anti-phospholipid Antibody Syndrome.” Universidad Austral, Valdivia, Chile

1993

- “Multidisciplinary Treatment of Arthritis.” Arthritis Foundation Symposium, Seattle, WA
- “Anti-phospholipid Syndrome.” Rheumatology Symposium, University of Washington, Seattle, WA
- “Silicone Related Disorders.” Grand Rounds, Swedish Hospital Medical Center, Seattle, WA
- “Silicone Related Disorders.” Lupus Society, Seattle, WA
- “Silicone Related Disorders.” OB/GYN Conference, Swedish Hospital Medical Center, Seattle, WA
- Moderator and Organizer. Sjogren’s Syndrome Foundation, National Symposium, Seattle, WA,
- “Sjogren’s Syndrome.” Sjogren’s Syndrome Society Symposium, Northwest Hospital, Seattle, WA
- “Rheumatoid Arthritis.” Washington State Nursing Association, Seattle, WA
- “Fibromyalgia.” CLE Lecture, Federal Attorney General’s Office, Seattle, WA
- “Distinguishing Fibromyalgia from Arthritis.” Searle, Chicago, IL
- Silicone Related Disorders Study Group, San Antonio, TX
- Eosinophilia-Myalgia Syndrome (EMS) Study Group, Washington, D.C.
- EMS Study Group - Neurocognitive Aspects, Seattle, WA
- EMS Study Group - Neurocognitive Aspects, Santa Fe, CA

1992

- “Fibromyalgia and Chronic Fatigue Syndrome.” Rheumatology Symposium, University of Washington, Seattle, WA
- “SLE.” Lupus Society, Seattle, WA
- “FM & CFS.” CFS Society, Seattle, WA
- “Anti-phospholipid Syndrome.” Pacific Northwest Vascular Society, Seattle, WA
- “FM/CFS.” OB/GYN Conference, Swedish Hospital Medical Center, Seattle, WA
- “The Shoulder.” Grand Rounds, Swedish Hospital Medical Center, Seattle, WA
- “FM/CFS.” CME Lecture, Northwest Hospital, Seattle, WA
- “Pharmacotherapy of Rheumatic Diseases.” Washington State Nursing Association, Seattle, WA
- “EMS.” NW Rheumatism Society, Seattle, WA
- “Neurocognitive Aspects of EMS.” American College Rheumatology, National Meeting, Atlanta, GA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
- EMS Study Group, Washington, D.C.

1991

- “Fibromyalgia and Chronic Fatigue Syndrome.” UW Rheumatology Symposium, Seattle, WA
- “Fibromyalgia and Chronic Fatigue Syndrome.” Soft Tissue Rheumatic Disease Study Group, American College of Rheumatology, National Meeting
- “FM & CFS.” CFS Society, Seattle, WA
- “FM & CFS.” FM Society, Seattle, WA
- “Organizer & Moderator.” Sjogren’s Syndrome Foundation, National Symposium, Seattle, WA
- “FM/CFS.” CME, Ballard Hospital, Seattle, WA
- “Soft Tissue Rheumatism.” Washington State Nursing Association, Seattle, WA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
- EMS Study GroupWashington, D.C.

1990

- “FM/CFS.” CME Symposium, UW OB/GYN, Seattle, WA
- “FM/CFS.” CFS Society, Seattle, WA
- “FM/CFS.” CFS Society, Bellevue, WA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA

1989

- “FM/CFS.” Arthritis Day, Seattle, WA
- “Arthritis.” Arthritis Foundation, Seattle, WA
- First International Symposium on CFS Fibromyalgia, Seattle, WA

1988
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
1987
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
1986
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
1985

- - “Soft Tissue Rheumatism.” Cabrini Hospital, Seattle, WA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA

1984
- “Crystalline Arthritis.” Cabrini Hospital, Seattle, WA
- “Raynaud’s.” Providence Hospital, Seattle, WA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA
1983

- “Raynaud’s.” Cabrini Hospital, Seattle, WA
- “Arthritis.” Arthritis Foundation Speakers Bureau, Seattle, WA