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Submitted

Kishida KT*, Sandberg SG*, Lohrenz T, Comair YG, Phillips PEM and Montague RM (submitted) Sub-second dopamine measurements in human striatum during a sequential investment game. Nature Neuroscience.

Parker JG, Zweifel LS, Clark JJ, Evans SB, Phillips PEM and Palmiter RD (submitted) Absence of NMDA receptors in dopamine neurons attenuates dopamine release but not Pavlovian conditioning. Journal of Neuroscience.

Ferguson SM, Wanat MJ, Eskenazi D, Phillips PEM, Roth BL and Neumaier JF (submitted) Transient neuronal silencing reveals opposing actions of indirect and direct pathway neurons on amphetamine sensitization. Nature Neuroscience.

2009

Clark JJ*, Sandberg SG*, Wanat MJ, Gan JO, Horne EA, Hart AS, Parker JG, Akers CA, Willuhn I, Martinez V, Evans SB, Stella N and Phillips PEM (2009) Chronic microsensors for longitudinal subsecond dopamine detection in behaving animals. Nature Methods, in press.

Gan JO*, Walton ME* and Phillips PEM (2009) Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine. Nature Neuroscience, in press • PDF

Ford CP, Phillips PEM and Williams JT (2009) The time course of dopamine transmission in the ventral tegmental area. Journal of Neuroscience, 29, 13344-13352 • PDF

Flagel SB, Robinson TE, Clark JJ, Clinton SM, Watson SJ, Seeman P, Phillips PEM and Akil H (2009) An animal model of genetic vulnerability to behavioral disinhibition and cue reactivity: Implications for addiction. Neuropsychopharmacology, in press • PDF

Kroener S, Chandler LJ, Phillips PEM and Seamans JK (2009) Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex. PLoS One 4 e6507 • PDF

Zhang L, Doyon WM, Clark JJ, Phillips PEM and Dani JA (2009) Controls of tonic and phasic dopamine transmission in the dorsal and ventral striatum. Molecular Pharmacology 76, 396-340 • PDF

Willuhn I, Wanat MW, Clark JJ and Phillips PEM (2009) Dopamine signaling in the nucleus accumbens of animals self-administering drugs of abuse. In: Self DW and Staley J (eds) Behavioral Neuroscience of Drug Addiction. Springer-Verlag, in press.

Beckstead MJ, Ford CP, Gantz SC, Stenzel-Poore MP, Phillips PEM, Mark GP and Williams JT (2009) CRF enhancement of GIRK channel-mediated transmission in dopamine neurons. Neuropsychopharmacology 34, 1926-1935 • PDF

Zweifel LS, Parker JG, Rainwater A, Wall VZ, Lobb CJ, Fadok JP, Kim MJ, Mizumori S, Paladini CA, Phillips PEM, and Palmiter RD (2009) Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proceedings of the National Academy of Sciences of the United States of America 106, 7281-7288 • PDF

Wanat MJ, Willuhn I, Clark JJ and Phillips PEM (2009) Phasic dopamine release in appetitive behaviors and drug addiction. Current Drug Abuse Reviews 2, 195-213 • PDF

Hart AS, Walton ME and Phillips PEM (2009) Neuroeconomics. Encyclopedia of Life Sciences, in press • PDF

Sandberg SG and Phillips PEM (2009) Phasic dopaminergic signaling: Implications for Parkinson’s disease. In: Tseng KY (ed) Cortico-subcortical Dynamics in Parkinson’s Disease. Humana Press, Totowa, NJ, in press.

2008

Knutson B, Delgado MR and Phillips PEM (2008) Representation of subjective value in the striatum. In: Glimcher PW, Camerer CF, Fehr E and Poldrack RA (eds) Neuroeconomics: Decision Making and the Brain. Academic Press, New York.

Ting JT and Phillips PEM (2008) Neurotransmitter: release. Wiley Encyclopedia of Chemical Biology. John Wiley & Sons. DOI: 10.1002/9780470048672.wecb385 • PDF

Phillips PEM, Sandberg SG, Ahn S and Phillips AG (eds) Monitoring Molecules in Neuroscience. UBC Institute of Psychiatry, Vancouver, BC, 2008.

Wanat MJ, Hopf FW, Stuber GD, Phillips PEM and Bonci A (2008) Corticotropin-releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C-dependent enhancement of I_h. Journal of Physiology 586, 2157-2170 • PDF

2007

Wightman RM, Heien MLAV, Wassum KM, Sombers LA, Aragona BJ, Khan AS, Ariansen JL, Cheer JF, Phillips PEM, and Carelli RM (2007) Dopamine release is heterogeneous within microenvironments of the rat brain. European Journal of Neuroscience 26, 2046-2054 • PDF

Beckstead MJ, Ford CP, Phillips PEM and Williams JT (2007) Presynaptic regulation of dendrodendritic dopamine transmission. European Journal of Neuroscience 26, 1479-1488 • PDF

Kita JM, Parker LE, Phillips PEM, Garris PA and Wightman RM (2007) Paradoxical modulation of short-term facilitation of dopamine release by dopamine D2 receptors. Journal of Neurochemistry 102, 1115-1124 • PDF

Phillips PEM, Walton ME and Jhou TC (2007) Calculating utility: cost-benefit analysis by mesolimbic dopamine. Psychopharmacology 191, 483-495 • PDF

Cheer JF, Wassum KM, Sombers LA, Heien MLAV, Ariansen JL, Aragona BJ, Phillips PEM and Wightman RM (2007) Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation. Journal of Neuroscience 27, 791-795 • PDF

2006

Walton ME, Kennerley SW, Bannerman DM, Phillips PEM and Rushworth MFS (2006) Weighing up the benefits of work: Behavioral and neural analyses of effort-related decision making. Neural Networks 19, 1302-1314 • PDF

Gitler D, Feng J, Takagishi Y, Pogorelov VM, Rodriguiz RM, Venton BJ, Phillips PEM, Ren Y, Kao HT, Wightman M, Greengard P, Wetsel WC and Augustine GJ (2006) Synaptic vesicle trafficking and drug addiction in synapsin triple knockout mice. In: Madras BK, Colvis CM, Pollock JD, Rutter JL, Shurtleff D and Zastrow MV (eds) Cell Biology of Addiction. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

Hnasko TS, Perez FA, Scouras AD, Stoll EA, Gale SD, Luquet S, Phillips PEM, Kremer EJ and Palmiter RD (2006) Cre-recombinase mediated restoration of nigrostriatal dopamine in a dopamine-deficient mouse reverses hypophagia and bradykinesia. Proceedings of the National Academy of Sciences of the United States of America 103, 8858-8863 • PDF

Venton BJ, Seipel AT, Phillips PEM, Wetsel WC, Gitler D, Greengard P, Augustine GJ and Wightman RM (2006) Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. Journal of Neuroscience 26, 3206-3209 • PDF

2005

Vitaliano PP, Echeverria D, Yi J, Phillips PEM, Young H and Siegler IC (2005) Psychophysiological mediators of caregiver stress and differential cognitive decline. Psychology and Aging 20, 402-411 • PDF

Heien MLAV, Khan AS, Ariansen JL, Cheer JF, Phillips PEM, Wassum KM and Wightman RM (2005) Real-time measurement of dopamine fluctuations following cocaine in the brain of behaving rats. Proceedings of the National Academy of Sciences of the United States of America 102, 10023-10028 • PDF

Lavin A, Nogueira L, Lapish CC, Wightman RM, Phillips PEM and Seamans JK (2005) Mesocortical dopamine neurons operate on distinct temporal domains using multimodal signaling. Journal of Neuroscience 25, 5013-5023 • PDF

Stuber GD, Roitman MF, Phillips PEM, Carelli RM and Wightman RM (2005) Rapid dopamine signaling in the nucleus accumbens during contingent and noncontingent cocaine administration. Neuropsychopharmacology 30, 853-863 • PDF

2004

Cheer JF, Wassum KM, Heien MLAV, Phillips PEM and Wightman RM (2004) Cannabinoids enhance subsecond dopamine release in the nucleus accumbens of awake rats. Journal of Neuroscience 24, 4393-4400 • PDF

Phillips PEM and Wightman RM (2004) Extrasynaptic dopamine and phasic neuronal activity (correspondence). Nature Neuroscience 7, 199 • PDF

Montague PR, McClure SM, Baldwin PR, Phillips PEM, Budygin EA, Stuber GD, Kilpatrick MR and Wightman RM (2004) Dynamic gain control of dopamine delivery in freely moving animals. Journal of Neuroscience 24, 1754-1759 • PDF

Roitman MF, Stuber GD, Phillips PEM, Wightman RM and Carelli RM (2004) Dopamine operates as a subsecond modulator of food seeking. Journal of Neuroscience 24 1265-1271 • PDF

2003

Heien MLAV, Phillips PEM, Stuber GD, Seipel AT and Wightman RM (2003) Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorbtion and increases sensitivity. Analyst 128, 1413-1419 • PDF

Venton BJ, Zhang H, Garris PA, Phillips PEM, Sulzer D and Wightman RM (2003) Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing. Journal of Neurochemistry 87, 1284-1295 • PDF

Phillips PEM and Wightman RM (2003) Critical guidelines for validation of the selectivity of in-vivo chemical microsensors. Trends in Analytical Chemistry 22, 509-514 • PDF

Garris PA, Budygin EA, Phillips PEM, Trafton BJ, Robinson DL, Bergstom BP, Rebec GV and Wightman RM (2003) A role for presynaptic mechanisms in the actions of nomifensine and haloperidol. Neuroscience 118, 819-829 • PDF

Phillips PEM, Stuber GD, Heien MLAV, Wightman RM and Carelli RM (2003) Subsecond dopamine release promotes cocaine seeking. Nature 422, 614-618 • PDF

Phillips PEM, Johns JM, Lubin DA, Budygin EA, Gainetdinov RR, Lieberman JA and Wightman RM (2003) Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally-exposed to cocaine. Brain Research 961, 63-72 • PDF

Phillips PEM, Robinson DL Stuber GD, Carelli RM and Wightman RM (2003) Real-time measurements of phasic changes in extracellular dopamine concentration in freely-moving rats by fast-scan cyclic voltammetry. In: Wang JQ (ed) Drugs of Abuse: Neurological Reviews and Protocols. Humana Press, Totowa, NJ, 443-464 • PDF

2002

Phillips PEM, Budygin EA, Robinson DL and Wightman RM (2002) Fast-scan cyclic voltammetry in freely-moving rats. In: Nagatsu T, Nabeshima T, McCarty R and Goldstein DS (eds) Catecholamine Research: From Molecular Insights to Clinical Medicine. Kluwer Academic/Plenum Publishers, New York, NY, 305-308.

Phillips PEM, Hancock PJ and Stamford JA (2002) The time window of autoreceptor-mediated inhibition of limbic and striatal dopamine release. Synapse 44, 15-22 • PDF

2001

Budygin EA, Phillips PEM, Wightman RM and Jones SR (2001) Terminal effects of ethanol on dopamine dynamics in rat nucleus accumbens: An in vitro voltammetric study. Synapse 42, 77-79 • PDF

Robinson DL, Phillips PEM, Budygin EA, Trafton BJ, Garris PA and Wightman RM (2001) Sub-second changes in accumbal dopamine during sexual behavior in male rats. Neuroreport 12, 2549-2552 • PDF

Budygin EA, Phillips PEM, Robinson DL, Kennedy AP, Gainetdinov RR and Wightman RM (2001) Effect of acute ethanol on striatal dopamine neurotransmission in ambulatory rats. Journal of Pharmacology and Experimental Therapeutics 297, 27-34 • PDF

20^th Century

Phillips PEM and Stamford JA (2000) Differential recruitment of N-, P- and Q-type voltage-operated calcium channels in striatal dopamine release evoked by ‘regular’ and ‘burst’ firing patterns. Brain Research 884, 139-146 • PDF

Schulte D, Callado LF, Davidson C, Phillips PEM, Roewer N, Schulte am Esch J and Stamford JA (2000) Propofol decreases stimulated dopamine release in the rat nucleus accumbens by a mechanism independent of dopamine D2, GABA_A and NMDA receptors. British Journal of Anaesthesia 84, 250-253 • PDF

Phillips PEM and Stamford JA (1999) Voltammogram “landscapes” aid detection and identification of in vivo electrochemical signals. Electroanalysis 11, 301-307 • PDF

Phillips PEM and Stamford JA (1998) Interaction between dopamine uptake and autoreceptor function in the nucleus accumbens in vitro. European Journal of Neuroscience 10, 147.22.

Phillips PEM, Hancock PJ and Stamford JA (1997) The timecourse of D2 autoreceptor action in the nucleus accumbens and neostriatum following single pulse electrical stimulation in vitro. British Journal of Pharmacology 122, 316P.

Schulte D, Davidson C, Phillips PEM, Roewer N, Schulte Am Esch J and Stamford JA (1995) Propofol decreases stimulated dopamine release in the rat ventral striatum by a mechanism involving neither dopamine D2 receptors, nor GABA_A receptors. Anesthesiology 83, A749.

Stamford JA, Palij P, Davidson C, Jorm CM and Phillips PEM (1995) Fast cyclic voltammetry in brain slices. In: Boulton A, Baker GB and Adams RN (eds) Voltammetric Methods in Brain Systems. Humana Press, Totowa, NJ.

Phillips PEM and Stamford JA (1995) Cascade analysis identification of low-level electrochemical signals in vivo. British Journal of Pharmacolology 115, 82P.

Lipton P, Aitken PG, Dudek FE, Eskessen K, Espanol MT, Ferchmin PA, Kelly JB, Kreisman NR, Landfield PW, Larkman PM, Leybaert L, Newman GC, Panizzon KL, Payne RS, Phillips P, Raley-Susman KM, Rice ME, Santamaria R, Sarvey JM, Schurr A, Segal M, Sejer V, Taylor CP and Teyler TJ (1995) Making the best of brain slices: Comparing preparative methods. Journal of Neuroscience Methods 59, 151-156 • PDF

* denotes equal contrubtion of authors

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