Rho D ALLOIMMUNIZATION


About 17% of Rh-negative women who don't receive anti-D immune globulin ("RhoGAM") will become alloimmunized.

Alloimmunization is caused by feto-maternal hemorrhage which occurs at delivery (90% of cases) as well as at certain prenatal events:

Standard is to give RhoGAM if:

RhoGAM is unnecessary if:

If delivery hasn't occurred within 12wks after the first dose, a 2nd dose is advised

Dosing:

(Source: ACOG Practice Bulletin #4, 5/94)