PLATELET DISORDERS


Causes of Thrombocytopenia

Idiopathic Thrombocytopenic Purpura

Thrombotic Thrombocytopenic Purpura

Common wisdom has it that initial bleeding due to platelet disorders is usually from mucous membranes rather than bruising of the skin or hemarthrosis

Essential thrombocythemia

Eltrombopag is a (as of 2007) investigational agent that is orally active and acts as an agonist at thrombopoietin receptors and may hold promise in treating various forms of thrombocytopenia.

Platelet transfusion: Usual threshold for platelet transfusion in patients not having active bleeding or undergoing an invasive procedure is < 10k/microliter)