CAUSES OF SPLENOMEGALY IN KIDS


I. Infectious/Inflammatory

  1. TORCH, mono, TB, typhoid, malaria, brucella, schistosomiasis, SBE, sepsis
  2. JRA, SLE, Felty's Sd., sarcoid

II. Congestive

  1. CHF, Budd-Chiari Sd., congestive pericarditis, "cavernous transformation" (?)

III. Sequestrative

  1. SSA, thalassemias
  2. RBC enzyme deficiencies
  3. Rh/ABO incompatibilities
  4. Autoimmune hemolytic anemias
  5. Galactosemias
  6. Wolman's Sd.
  7. Reye's Sd
  8. Tetracyclines

IV. Infiltrative

  1. Leukemia, lymphoma
  2. Histiocytosis
  3. Polycythemia
  4. Metastatic neuroblastoma
  5. Myelofibrosis

V. Other: trauma, hemangioma, cysts