NECROBIOSIS LIPOIDICA DIABETICORUM


In an open-label study of 18 pts with biopsy-proven NLD given oral fumaric acid esters for at least 6mos (6 with type 1 DM, 6 with type 2 DM, and 6 with no DM), significant improvement occurred in all pts; some GI side effects were noted, as well as flushing. (Br. J. Dermatol. 153:802, 2005--JW)