CHEMOTHERAPEUTIC DRUGS


I. Alklating agents
  1. Examples: cyclophosphamide (Cytoxan)
  2. Can damage bone marrow stem cells leading to leukemia
II. Anthracyclines
  1. Can cause (dose-related) cardiac damage
    1. Doxorubicin (Adriamycin)-Associated with acute myeloblastic leukemia, poorly responsive to therapy
    2. Epirubicin (Ellence)
    3. Daunorubicin (Cerubidine)
III. Taxanes (e.g. Taxol)-Can cause peripheral neuropathy
IV. Vinca alkaloids (e.g. vincristine)-Can cause peripheral neuropathy
V. Epothilones-Can cause peripheral neuropathy