AUTOIMMUNE HEPATITIS


Diagnosis

Hepatitis B AND Hepatitis C-negative 2
IgG > 1.0 but ≤ 1.1 x upper limit of normal
IgG > 1.1 x upper limit of normal
1
2
SMA or ANA ≥ 1:40
(SMA or ANA ≥ 1:80 OR LKM ≥ 1:40 OR SLA/LP positive)
1
2
Liver biopsy compatible with AIH
Liver biopsy typical for AIH
1
2

SMA = smooth muscle actin

ANA = antinuclear antivody

AMA = antimitochondrial antibody

LKM = liver-kidney microsomal antibodies

SLA/LP = soluble liver/liver-pancreas antibodies (highly specific to AIH)

Treatment

(Sources include Core Content Review of Family Medicine, 2012)