ALCOHOLISM


ACUTE ALCOHOL WITHDRAWAL

DIAGNOSIS OF ALCOHOLISM

Naltrexone (an opioid antagonist) for tx of alcoholism:

Nalmefene (an opioid antagonist) for tx of alcoholism:

Ondansetron (an antiemetic) was ass'd with sig. reduced self-reported drinking compared with placebo in a randomized trial in 271 alcoholics 25-65yo; the benefit was limited to those pts with "early-onset" alcohlism (onset at < 25yo) (JAMA 284:963, 2000--JW)

Topiramate can reduce cravings and improve abstinence (Arch. Gen. Psychiat. 61:905, 2004--AFP)

Others in the pipeline: Acamprosate