Selected Publications

Lang KS, Hall AN, Merrikh CN, Ragheb M, Merrikh H. Head-on replication-transcription collisions lead to formation of life threatening R-loops. Cell 2017 Aug 10. Link
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Loftie-Eaton W, Bashford K, Quinn H, Dong K, Millstein J, Hunter S, Thomason M, Merrikh H, Ponciano JM, and Top EM. Compensatory mutations improve general permissiveness to antibiotic resistance plasmids. Nature Ecology and Evolution. 2017 Aug 7. Link
Merrikh H. Spatial and Temporal Control of Evolution through Replication-Transcription Conflicts. Trends in Microbiology 2017 Jul 25. Link
Mangiameli S, Merrikh CN, Wiggins PA, Merrikh H. Transcription leads to pervasive replisome instability in bacteria. eLife 2017 Jan 16. Link
Mangiameli S, Veit BT, Merrikh H, Wiggins P. The replisomes remain spatially proximal throughout the cell cycle in bacteria. PLoS Genetics 2017 Jan 23. Link
Merrikh CN, Weiss E, Merrikh H. The accelerated evolution of lagging strand genes is independent of sequence context. Genome Biol Evol. 2016 Nov 6. Link
Merrikh CN, Brewer BJ, Merrikh H. The B. subtilis accessory helicase PcrA facilitates DNA replication through transcription units, PLoS Genetics. 2015 Jun 12;11(6):e1005289.
Million-Weaver S, Samadpour AN, and Merrikh H. Replication restart after replication-transcription conflicts requires RecA in Bacillus subtilis, J Bacteriology. 2015 May 4. pii: JB.00237-15.
Million-Weaver S, Samadpour AN, Moreno-Habel D, Nugent P, Weiss E, Brittnacher M, Hayden H, Miller SI, Liachko I, and Merrikh H. An underlying mechanism for increased mutagenesis of lagging strand genes in Bacillus Subtilis. Proc Natl Acad Sci USA. 2015 Mar 10;112(10):E1096-105.
Paul S, Million-Weaver S, Cattopadhyay S, Sokurenko E, and Merrikh H. Accelerated gene evolution through replication-transcription conflicts. Nature. 2013 Mar 28;495(7442):512-5.
Merrikh H, Zhang Y, Grossman AD and Wang JD. Replication-transcription conflicts in bacteria. Nature Reviews Microbiology. 2012 Jun; 10(7):449-58.
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