Selected Publications

Merrikh CN, Merrikh H. Gene inversion increases evolvability in bacteria. BioRxiv 2018 Apr 3. Link
Mangiameli SM, Cass JA, Merrikh H, Wiggins PA. The bacterial replisome has factory-like localization. Curr Genet. 2018 Apr 9. Link
Samadpour AN, Merrikh H. DNA gyrase activity regulates DnaA-dependent replication initiation in Bacillus subtilis. Mol Microbiol. 2018 Apr;108(2):115-127. Link
Lang KS, Hall AN, Merrikh CN, Ragheb M, Tabakh H, Pollock AJ, Woodward JJ, Dreifus JE, Merrikh H. Replication-Transcription Conflicts Generate R-Loops that Orchestrate Bacterial Stress Survival and Pathogenesis. Cell 2017 Aug 10. Link
Access the recommendation on F1000Prime
Loftie-Eaton W, Bashford K, Quinn H, Dong K, Millstein J, Hunter S, Thomason M, Merrikh H, Ponciano JM, and Top EM. Compensatory mutations improve general permissiveness to antibiotic resistance plasmids. Nature Ecology and Evolution. 2017 Aug 7. Link
Merrikh H. Spatial and Temporal Control of Evolution through Replication-Transcription Conflicts. Trends in Microbiology 2017 Jul 25. Link
Mangiameli S, Merrikh CN, Wiggins PA, Merrikh H. Transcription leads to pervasive replisome instability in bacteria. eLife 2017 Jan 16. Link
Mangiameli S, Veit BT, Merrikh H, Wiggins P. The replisomes remain spatially proximal throughout the cell cycle in bacteria. PLoS Genetics 2017 Jan 23. Link
Merrikh CN, Weiss E, Merrikh H. The accelerated evolution of lagging strand genes is independent of sequence context. Genome Biol Evol. 2016 Nov 6. Link
Merrikh CN, Brewer BJ, Merrikh H. The B. subtilis accessory helicase PcrA facilitates DNA replication through transcription units, PLoS Genetics. 2015 Jun 12;11(6):e1005289.Link
Million-Weaver S, Samadpour AN, and Merrikh H. Replication restart after replication-transcription conflicts requires RecA in Bacillus subtilis, J Bacteriology. 2015 May 4. pii: JB.00237-15.Link
Million-Weaver S, Samadpour AN, Moreno-Habel D, Nugent P, Weiss E, Brittnacher M, Hayden H, Miller SI, Liachko I, and Merrikh H. An underlying mechanism for increased mutagenesis of lagging strand genes in Bacillus Subtilis. Proc Natl Acad Sci USA. 2015 Mar 10;112(10):E1096-105. Link
Paul S, Million-Weaver S, Cattopadhyay S, Sokurenko E, and Merrikh H. Accelerated gene evolution through replication-transcription conflicts. Nature. 2013 Mar 28;495(7442):512-5. Link
Merrikh H, Zhang Y, Grossman AD and Wang JD. Replication-transcription conflicts in bacteria. Nature Reviews Microbiology. 2012 Jun; 10(7):449-58.Link
Full Publication List