Job Openings

Postdoc in cryoEM

     A postdoc/research associate position supported by a new 5-year NIH R01 grant is available immediately in the Department of Biological Structure, University of Washington. This project focuses on structural study of membrane proteins. The newly developed "random spherically constrained" (RSC) single-particle cryo-EM method will be employed to study membrane protein structures in membrane environments. The RSC method has been successfully applied to obtain the structure of the large conductance voltage- and calcium-activated potassium (BK) channel in a lipid membrane (Nature, 461, 292-295).

     The research of the position focuses on the improvement of this method and the application of this method to other membrane proteins. Experience in membrane protein expression and purification is desirable, and experience in electron microscopy and image processing is preferable. Interested candidates should send CV and reference information to LW32@UW.EDU.