J o h n L e i g h L a b
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John Leigh, Ph.D.
KyleI am a Graduate student in the lab. My thesis project involves understanding and characterizing novel paths electron flow and energy conservation in methanogenesis. I am also interested in utilizing Methanococcus maripaludis for the production of biofuels such as hydrogen and methane. I participate in the University of Washington Astrobiology Program .
TomMy work focuses on the areas of nitrogen and hydrogen regulation in M. maripaludis. I am characterizing NrpR, a novel archaeal transcriptional regulator, and its mechanism of gene regulation. In the area of hydrogen regulation, my study revolves around the identification of the signal(s) for hydrogen starvation as well as the mechanisms of gene regulation. Another interest is in the applied aspects of M. maripaludis metabolism.
JohnJohn Leigh received his Ph.D. at the University of Illinois working with Ralph Wolfe. He did a postdoc with Graham Walker at MIT, then moved to his faculty position at the University of Washington. John's lab has been working on regulation in Methanococcus maripaludis since 1994, and this remains his main passion. He also enjoys hiking and Astrobiology field trips. Recently, for his 50th birthday, the lab presented him with a large birthday "card" written in luminescent bacteria, picturing his favorite coenzyme, methanofuran.
Former Lab Members
JeremyI joined the Leigh lab in the summer of 2001. My thesis project involves understanding post-translational regulation of nitrogen fixation in M. maripaludis. I am also involved in the UW-Seattle Astrobiology program: http://depts.washington.edu/astrobio/
ErikI received my bachelor's degree in chemistry from Harvey Mudd College and my PhD in genetics from Harvard. My post doctoral work in John Leigh's lab focuses on transcriptional regulation by hydrogen as well as the genome sequencing and RNA array projects.
Hobbies: enjoy playing anything that can get more oxygen into my brain!!