Researchers
Juergen Meyer, Alicia Cavan, Peifeng Jing, Prof Lih Lin, Kaidi Liang, Dr Frederique Vanholsbeeck, Adrien Carlu
Overview
The aim
of this research is to develop a novel radiation
dosimeter based on Digital Holographic
Interferometry (DHI) for novel applications,
such as e.g. microbeam radiotherapy or our small
animal proton IGRT facility. DHI is an optical
technique, which is capable of detecting
miniscule radiation-induced temperature changes
in a water phantom by means of a laser
interferometer. The approach is based on
digitally capturing laser interference patters,
which are governed by the change in temperature
of the irradiated medium. From these patterns
the phase changes can be extracted and
mathematically directly related to the radiation
absorbed dose. The dosimeter is independent of
radiation type and can resolve spatial
variations in absorbed dose. A schematic
overview of the approach is shown below on the
left. The current experimental set-up is based
on a Lensless Fourier digital holography (LFTDH)
approach and uses a CMOS camera for recording as
shown in the picture on the right.
A simplified illustration of the DHI dosimeter. | Lensless Fourier digital holography set-up. The water cell is the dosimetry medium. |
Links and collaboration
UWEE
Photonics Lab at the University of
Washington, Seattle, WA
Biophotonics
Lab at the University of Auckland, New
Zealand
References
A Cavan, J Meyer, “Accounting for Heat Diffusion
in High Spatial Resolution Calorimetric Dosimetry
with Digital Holographic Interferometry”,
presented at 2014 NW AAPM Fall Meeting, Seattle,
WA, 7 November 2014
A Cavan, J Meyer, Digital holographic
interferometry: A novel optical calorimetry
technique for radiation dosimetry. Med Phys,
41(2), 2014
J Meyer, A Cavan. Development of a novel spatial
calorimetry technique for high dose rate radiation
dosimetry. 2013 AAPM NW Fall Chapter Meeting,
Seattle, WA
A Cavan, J Meyer, A Novel Optical Calorimeter
Applied to Proton Beam Dosimetry, AAPM 55th Annual
Meeting, Indianapolis, IN, August 4-8, 2013
A Cavan, J Meyer. Evaluation of a novel digital
holographic interferometer for dosimetry of high
dose rate brachytherapy sources. 44th Annual
Meeting of the German Society of Medical Physics
(DGMP), 18-21 September 2013, Cologne, Germany
A
Cavan, J Meyer, A novel optical calorimetry
dosimetry approach applied to an HDR
Brachytherapy source, J. Phys.: Conf. Ser. 444
012069, 2013
A E
Cavan and J Meyer, "Digital Holographic
Interferometry: Development of an optical
calorimetry technique for radiation dosimetry",
presented at Engineering and Physical
Sciences in Medicine (EPSM 2012),
Brisbane, Australia, 02-06
December 2012
A E Cavan and J Meyer, "A novel optical
calorimetry dosimetry approach applied to an HDR
Brachytherapy source" presented at IC3DDOSE ", presented
at the 7th international conference on 3D
radiation dosimetry, Sydney, Australia,
04-08 November, 2012
K Liang, "A fibre optics approach to radiation
dosimetry", MSc thesis, University of
Canterbury, Christchurch, New Zealand, 2012
A Cavan, R Watts and J Meyer, ‘Initial investigation of digital holographic interferometry as a pseudo-calorimetric dosimetry method for microbeam radiotherapy (MRT)’, at New Zealand Institute of Physics (NZIP) Conference 2011, 17th – 19th October 2011, Wellington, New Zealand
A Cavan, P Wilson and J Meyer, A viscoelastic model of respiratory lung tumour motion, The New Zealand Medical Journal, Proceedings of the Health Research Society of Canterbury Seminar Series 123 (1313), 85 (2010).
A Cavan, A
Carlu, J Meyer, ‘Pseudo-calorimetric dosimetry
for Microbeam Radiotherapy (MRT) based on
optical interference’, at Engineering and
Physical Sciences in Medicine and the
Australian Biomedical Engineering Conference
(EPSM ABEC 2010), Melbourne,
Australia, 05-09 December
2010
A
Carlu, "The use of holographic interferometry to
determine the ratio of refractive indices for a
striated medium", MDPH409 project report,
University of Canterbury, Christchurch, New
Zealand, 2010
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