Chemoreception in single cells (sperm and bacteria)

Chemical communication is not only critical in mediating macroorganismal interactions, but plays a profound importance in controlling processes that occur at the level of the single cell. In contrast to the neural approach used for insect olfaction, the relatively simple system of the single cell permits a molecular approach towards understanding the physiological mechanisms controlling chemosensory behavior. This work integrates calcium imaging, cell motility, and microfluidics to understand the fluid dynamical basis of chemosensory behavior in sperm or bacteria.