- Psoter, K....Wakefield, J. (2014). Differential geographical risk of initial Pseudomonas aeruginosa acquisition in young U.S. children with cystic fibrosis. To appear in
*American Journal of Epidemiology.* - Wakefield, J.C., Skrivankova, V., Hsu, F.-C., Sale, M. and Heagerty, P. (2014). Detecting signals in pharmacogenomic studies.
*The Pharmacogenomics Journal.*Published online January, 2014. - Glynn, A. and Wakefield, J. (2014). Alleviating ecological bias in Poisson models using optimal subsampling: The effects of Jim Crow on black illiteracy in the Robinson data". To appear in
*Sociological Methodology.*### 2013

- Skelly, et al (2013). Integrative phemomics reveals insight into the structure of phenotypic diversity in budding yeast.
*Genome Research*, 23, 1496-1504. - Psoter, K.J., de Roos, A.J, Wakefield, J., Mayer, J.D. and Rosenfeld, M. (2013). Season is associated with Pseudomonas aeruginosa acquisition in young children with cystic fibrosis. To appear in
*Clinical Microbiology and Infection.* - Zheng, Z., Shen, J., Cox, C., Wakefield, J.C., Ehm, M.G., Nelson, M.R. and Weir, B.S. (2013). HIBAG - HLA genotype imputation with attribute bagging.
*The Pharmacogenomics Journal*, published online May 2013. - Shaddick G., Lee D. and Wakefield J. (2013). Ecological bias in studies of the short-term effects of air pollution on health.
*International Journal of Applied Earth Observation and Geoinformation,*22, 65-74. - Wakefield, J. and Kim, A. (2013). A Bayesian model for cluster detection.
*Biostatistics*, 14, 752-765. - Hoff, P. and Wakefield, J. (2013). A Bayesian sandwich estimator. To appear in
*Journal of Statistical Planning and Inference*(as a discussion of Stephen Walker's "Bayesian inference with misspecified models"). - Ross, M.E. and Wakefield, J.C. (2013). Bayesian inference for two-phase studies with categorical covariates.
*Biometrics*, 69, 469-477. - Islami, F.,...,Wakefield, J. ... (2013). Smoking water-pipe, chewing nass, and prevalence of heart disease -- A cross-sectional analysis of baseline data from the Golestan cohort study, Iran.
*Heart*, 99, 272--278.### 2012

- Fong, Y., Wakefield, J., De Rosa, S. and Frahm, N. (2012). A robust Bayesian random effects model for nonlinear calibration problems.
*Biometrics*, 68, 1103--1112. - Johansson, M.,...,Wakefield, J. and Mckay, J.D. (2012). Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4 - the AdAPT method.
*PLoS One*, 7, e36888. - de Vocht, F., Cherry, N. and Wakefield, J (2012). A Bayesian mixture modeling approach for assessing the effects of correlated exposures in case-control studies.
*Journal of Exposure Science and Environmental Epidemiology*, 22, 352-360. - Fong, Y., Wakefield, J. and Rice, K. (2012). An efficient Markov chain Monte Carlo method for mixture models by neighborhood pruning.
*Journal of Computational and Graphical Statistics*, 21, 197-216.### 2011

- Skelly, D.A., Johansson, M., Madeoy, J., Wakefield, J. and Akey, J.M. (2011). A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-Seq data.
*Genome Research*, 21, 1728-1737. Paper can be accessed here - Wang, Y., Feng, Z., Yang, Y., Self, S., Gao, Y., Longini, I.M., Wakefield, J., Zhang, J., Wang, L., Chen, C., Yao, L., Stanaway, J.D., Wang, Z. and Yang, W. (2011). Hand, foot and mouth disease in China: patterns of spread and transmissibility during 2008-2009.
*Epidemiology*, 22, 781-792. - Wakefield, J., Haneuse, S., Dobra, A. and Teeple, E. (2011). Bayes computation for ecological inference.
*Statistics in Medicine,*30, 1381-1396.### 2010

- Ross, M.E., Wakefield, J., Davis, S. and De Roos, A.J (2010). Spatial clustering of myelodysplastic syndromes (MDS) in the Seattle-Puget sound region of Washington State.
*Cancer Causes Control*, 21, 829-838. - Wakefield, J. (2010). Bayesian methods for examining Hardy-Weinberg equilibrium.
*Biometrics*, 66, 257-265. - Glynn, A. and Wakefield (2010). Ecological inference in the social sciences.
*Statistical Methodology*, 7, 307-322. - Fong, Y., Rue, H. and Wakefield, J. (2010). Bayesian inference for generalized linear mixed models.
*Biostatistics*, 11, 397-412. - Fong, Y., Wakefield, J, and Rice, K. (2010). Bayesian mixture modeling using a hybrid sampler with application to protein subfamily identification.
*Biostatistics*, 11, 18-33. - Wakefield, J., de Vocht, F. and Hung, R.J. (2010). Bayesian mixture modeling of gene-environment and gene-gene interactions.
*Genetic Epidemiology*, 34, 16-25.### 2009

- Islami, F., Malekshah, A.F., Kimiagar, M., Pourshams, A., Wakefield, J., et al. (2009). Patterns of food and nutrient consumption in Northern Iran, a high-risk area for esophageal cancer,
*Nutrition and Cancer*, 61, 475-483. - Wakefield, J. (2009). Multi-level modelling, the ecologic fallacy, and hybrid study designs,
*International Journal of Epidemiology*, 38, 330-336. Illiteracy data Paper WinBUGS code - Islami, F., Kamangar, F., Nasrollahzadeh, D., Aghcheli, K., Sotoudeh, M., Abedi-Ardekani, B., Merat, S., Nasseri-Moghaddam, S., Semnani, S., Sepehr, A., Wakefield, J., et al. (2009). Socio-economic status and oesophageal cancer: results from a population-based case-control study in a high-risk area.
*International Journal of Epidemiology*, 38, 978-988. - Wakefield, J. (2009). Bayes factors for genome-wide association studies: comparison with p-values.
*Genetic Epidemiology*, 33, 79-86.### 2008

- Salway, R.E. and Wakefield, J. (2008). Gamma generalized linear models for pharmacokinetic data.
*Biometrics*, 64, 620-626. - Wakefield, J. (2008). Ecologic studies revisited.
*Annual Review of Public Health*29, 75-90. annrev08.pdf - Wakefield, J. (2008). Reporting and interpretation in genome-wide association studies.
*International Journal of Epidemiology*. wakefieldIJE.pdf 37, 641-653. - Wakefield, J. and Haneuse, S. (2008). Overcoming ecological bias using the two-phase study design.
*American Journal of Epidemiology*, 167, 908-916 wakefieldhaneuseAJE.pdf -
McKay, J.D. Hashibe, M, Hung, R.J., Wakefield, J., et al. (2008).
Sequence Variants of NAT1 and NAT2 and Other Xenometabolic Genes and Risk of Lung and Aerodigestive Tract Cancers in Central Europe.
*Cancer Epidemiology and Biomarkers*, 17, 141-147. - Haneuse, S. and Wakefield, J. (2008). The combination of ecological and case-control data.
*Journal of the Royal Statistical Society, Series B*, 70, 73-93 haneusewakefieldRSSB.pdf. - Glynn, A., Wakefield, J., Handcock, M. and Richardson, T.S. (2008). Alleviating linear ecological bias and optimal design with subsample data.
*Journal of the Royal Statistical Society, Series A*171, 179-202. glynnetalRSSA.pdf. - Li, S., Wakefield, J. and Self, S.G. (2008). A Trans-dimensional Bayesian model for pattern recognition in DNA sequence.
*Biostatistics*, 9, 668-685. - Salway, R. and Wakefield, J. (2007). A hybrid model for reducing ecological bias.
*Biostatistics*. 9, 1-17. Paper can be found here. - Haneuse, S. and Wakefield, J. (2007). Geographic-based ecological correlation studies using supplemental case-control data.
*Statistics in Medicine*, 27, 864-887.### 2007

- Wakefield, J. (2007). A Bayesian measure of the probability of false discovery in genetic
epidemiology studies.
*American Journal of Human Genetics*, 81, 208-227 Paper can be found here. - Elliott, P., Shaddick, G., Wakefield, J., de Hoogh, C. and Briggs, D.J. (2007). Long-term associations of outdoor air pollution with mortality in Great Britain.
*Thorax*, 62, 1088-1094. thorax2007.pdf - Haneuse, S., Wakefield, J. and Sheppard, L. (2007). The interpretation of exposure effect estimates in chronic air pollution studies.
*Statistics in Medicine*, 26, 3172-3187. Paper can be found here. - Haneuse, S. and Wakefield, J. (2007). Hierarchical models for combining
ecological and case-control data.
*Biometrics*, 63, 128-136. Paper can be found here. - Wakefield, J. (2007). Disease mapping and spatial regression with count data.
*Biostatistics*, 8, 158-183. Paper can be found here.### 2006

- Wakefield, J. and Shaddick, G. (2006). Health-exposure modelling and the ecological fallacy.
*Biostatistics*, 7, 438-455. Paper can be found here. - Zhou, C. and Wakefield, J. (2006). A Bayesian hierarchical mixture model
for curve partitioning.
*Biometrics*, 62, 515-526, Bugs Code - Gordian, M.E., Haneuse, S. and Wakefield, J. (2006). An investigation of the association between traffic exposure and the diagnosis of asthma.
*Journal of Exposure Science and Environmental Epidemiology*, 16, 49-55. - Hawkins, N., Self, S. and Wakefield, J (2006). The automated counting of spots for the ELISpot assay.
*Journal of Immunological Methods*, 316, 52-58. Paper can be found here.### 2005

- Whitaker, H., Best. N., Nieuwenhuijsen, M., Wakefield, J., Fawell, J. and Elliott, P. (2005). Modelling exposure to disinfection by-products in drinking water for an epidemiological study of adverse birth outcomes.
*Journal of Exposure Analysis and Environmental Epidemiology*, 15, 138-146. - Dabney, A. and Wakefield, J.C. (2005). Issues in the mapping of two diseases.
*Statistical Methods in Medical Research*, 14, 83-112.alan.pdf - Salway, R. and Wakefield, J.C. (2005). Sources of bias in ecological studies of non-rare events.
*Environmental and Ecological Statistics*, 12, 321-347.eesruth.pdf### 2004

- Bottle, R.A. and Wakefield, J.C. (2004). Statistical issues in
relation to the modeling of respiratory disease in relation to
cokeworks.
*Statistics in Medicine*, 23, 3139-3158. alex.pdf - Wakefield, J. (2004). Ecological inference for 2x2 tables (with discussion).
*Journal of the Royal Statistical Society, Series A*, 167, 385-445. read.pdf. Data can be found here. - Wakefield, J. (2004). A critique of statistical aspects of ecological
studies in spatial epidemiology.
*Environmental and Ecological Statistics*, 11, 31-54. ees.pdf### 2003

- Wakefield, J., Zhou, C. and Self, S. (2003). Modelling gene expression over
time: curve clustering with informative prior distributions.
*Bayesian Statistics 7, Proceedings of the Seventh Valencia International Meeting*, p. 721-732, Bernardo, J.M., Bayarri, M.J., Berger, J.O., Dawid, A.P., Heckerman, Smith, A.F.M., West, M. (editors), Oxford University Press. newval.pdf - Wakefield, J. (2003). Sensitivity analyses for ecological regression.
*Biometrics*, 59, 9-17. biometrics.pdf - Hickman, M., Madden, P., Henry, J., Baker, A., Wallace, C., Wakefield, J., Stimson, G. and Elliott, P. (2003). Trends in drug overdose deaths in England and Wales 1993-98: methadone does not kill more people than heroin.
*Addiction*, 98, 41-425.### 2002

- Guthrie, K.A., Sheppard, L. and Wakefield, J. (2002). A hierarchical aggregate data model with spatially correlated disease rates.
*Biometrics*, 58, 898-905. biomkath.pdf - Kelsall, J.E. and Wakefield, J.C. (2002).
Modeling spatial variation in disease risk: A geostatistical approach.
*Journal of the American Statistical Association*, 97, 692-701. - Shaddick, G. and Wakefield, J. (2002). Modelling multivariate
pollutant data at multiple sites.
*Applied Statistics*, 51, 351-372. appliedstats.pdf - Lunn, D.J., Best, N., Thomas, A., Wakefield, J. and Spiegelhalter, D.
(2002).
Bayesian analysis of population PK/PD models: General concepts and software.
*Journal of Pharmacokinetics and Pharmacodynamics*, 29, 271-307. - Jarup, L., Toledano, M.B., Best, N., Wakefield, J., Elliott P. (2002). Geographical
epidemiology of prostate cancer in Great Britain.
*International Journal of Epidemiology*, 97, 695-699. - Jarup, L., Briggs, D., de Hoogh, C., Morris, S., Hurt, C., Lewin, A., Maitland, I., Richardson, S., Wakefield, J., Elliott, P. (2002). Cancer risks in populations living near landfill sites in Great Britain,
*British Journal of Cancer*, 86, 1732-1736.### 2001

- Lunn, D.J., Wakefield, J.C. and Racine, A. (2001). Cumulative logit models for
ordinal data: a case study involving allergic rhinitis severity scores.
*Statistics in Medicine*, 20, 2261-2285. - Elliott, P., Briggs,D., Morris, S., de Hoogh, C., Hurt, C., Jensen, T.,
Maitland, I., Richardson, S., Wakefield, J. and Jarup, L. (2001)
Risk of adverse birth outcomes in populations living near landfill sites.
*British Medical Journal*, 323, 363-368. - Bennett, J.E. and Wakefield, J.C. (2001) Errors-in-variables in joint
population pharmacokinetic/pharmacodynamic modeling.
*Biometrics*, 57, 803-812. - Aylin, P., Bottle, A., Wakefield, J., Jarup, L., Elliott, P. (2001). Proximity to coke works
and hospital admissions for respiratory and cardiovascular disease in
England and Wales.
*Thorax*, 56, 228-233. - Wakefield, J.C. and Morris, S.E. (2001).
The Bayesian modeling of disease risk in relation to a point source.
*Journal of the American Statistical Association*, 96, 77-91. - Elliott, P. and Wakefield, J. (2001). Disease clusters: should they be investigated, and if so, when and how?
*Journal of the Royal Statistical Society, Series A*, 164, 3-12. - Wakefield, J. and Salway, R. (2001). A statistical framework for
ecological and aggregate studies.
*Journal of the Royal Statistical Society, Series A*, 164, 119-137. - Aylin, P., Morris, S., Wakefield, J., Grossinho, A., Jarup, L., Elliott, P.
(2001).
Temperature, housing, deprivation and their relationship to excess winter
mortality in Great Britain, 1986-1996.
*International Journal of Epidemiology*, 30, 1100-1108. - Best, N., Cockings, S., Bennett, J., Wakefield, J. and Elliott,
P. (2001). Ecological regression analysis of environmental benzene
exposure and childhood leukemia: sensitivity to data inaccuracies,
geographical scale and ecological bias.
*Journal of the Royal Statistical Society, Series A*, 164, 155-174. - Toledano, M., Jarup, L., Best, N., Wakefield, J.C, Elliott
P. (2001). Spatial and temporal trends of testicular cancer in Great
Britain.
*British Journal of Cancer*, 84, 1482-1487.### 2000

- Pascutto, C., Wakefield, J., Best, N., Bernardinelli, L., Elliott, P.,
Richardson, S. and Staines, A. (2000). Statistical issues in the analysis of disease mapping data.
*Statistics in Medicine*, 19, 2493-2519. - Wakefield, J.C. and Rahman, N. (2000). The combination of population
pharmacokinetic studies.
*Biometrics*, 56, 263-270. - Morris, S.E., Sale, R., Wakefield, J.C., Falconer, S., Elliott, P. and
Boucher, B.J. (2000).
Hospital admissions for asthma and chronic obstructive airways disease in
east London hospitals and proximity to major roads.
*Journal of Epidemiology and Community Health*, 54, 75-76. - Elliott, P., Arnold, R., Cockings, S., Eaton, N., Jarup, L., Jones, J., Quinn, M.,
Rosato, M., Thornton, I., Toledano, M., Tristan, E., Wakefield, J. (2000). Risk
of mortality, cancer incidence and stroke in a population potentially
exposed to cadmium.
*Occupational and Environmental Medicine*, 57, 94-97. - Diggle, P.J., Morris, S.E. and Wakefield, J.C. (2000). Point source modelling using
matched case-control data.
*Biostatistics*, 1, 89-105.### 1999

- Pauler, D.K., Wakefield, J.C. and Kass, R.E. (1999).
Bayes factors for variance component models.
*Journal of the American Statistical Association*, 94, 1242-1253. - Wakefield, J.C. and Morris, S.E. (1999).
An application of spatial errors-in-variables modelling: investigating the
relationship between ischaemic heart disease and water constituents.
*Bayesian Statistics 6, Proceedings of the Sixth Valencia International Meeting*, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M. (editors), p. 657-684, Oxford University Press. - Sheiner, L. and Wakefield, J. (1999),
Population modelling in drug development,
*Statistical Methods in Medical Research*, 8, 183-193. - Rahman, N.J., Wakefield, J.C., Stephens, D.A. and Falcoz, C. (1999),
Parameter estimation, model adequacy and assessment of dose proportionality
for pivotal pharmacokinetic study,
*Statistical Methods in Medical Research*, 8, 195-216. - Best, N.G. and Wakefield, J.C. (1999). Accounting for inaccuracies
in populations counts and case registration in cancer mapping studies.
*Journal of the Royal Statistical Society, Series A*, 162, 363-382. - Wakefield, J.C. and Elliott, P. (1999). Issues in the statistical
analysis of small-area health data.
*Statistics in Medicine*, 18, 2377-2399. - Aylin P, Maheswaran R, Wakefield J, Cockings S, Jarup L, Arnold R,
Wheeler G, Elliott P. (1999). A national facility for small area
disease mapping and rapid initial assessment of apparent disease
clusters around a point source: the UK Small Area Health Statistics
Unit.
*Journal of Public Health Medicine*, 21, 289-98. - Damien, P., Wakefield, J.C. and Walker, S.G. (1999).
Gibbs sampling for Bayesian nonconjugate and hierarchical models
using auxiliary variables.
*Journal of the Royal Statistical Society, Series B*, 61, 331-344. - Maheswaran, R., Morris, S.E., Falconer, S., Grossinho,
A., Wakefield, J.C. and Elliott, P. (1999).
Magnesium in drinking water supplies and mortality from acute
myocardial infarction in North West England.
*Heart*, 82, 455-460.### 1998

- Racine-Poon, A. and Wakefield, J.C. (1998).
Statistical methods for population pharmacokinetic modelling,
*Statistical Methods in Medical Research*, 7, 63-84. - Walker, S.G. and Wakefield, J.C. (1998). Population models with a nonparametric random coefficient distribution.
*Sankhya, Series B*, 60, 196-212. - Wakefield, J.C. (1998). The United Kingdom Small Area Health Statistics Unit.
*Journal of Japan Society for Atmospheric Environment*, 33, A60-A66.### 1997

- Wakefield, J.C. and Walker, S.G. (1997). Bayesian nonparametric population
models: formulation and comparison with likelihood approaches.
*Journal of Pharmacokinetics and Biopharmaceutics*, 25, 235-253. - Bennett, J.E., Wakefield, J.C. and Lacey, L.F. (1997). Modelling of
trough plasma bismuth concentrations.
*Journal of Pharmacokinetics and Biopharmaceutics*, 25, 79-106. - Wakefield, J.C. and Walker, S.G. (1997). A population approach to initial dose
selection.
*Statistics in Medicine*, 16, 1135-1149.### 1996

- Walker, S.G. and Wakefield, J.C. (1996). Bayesian approaches to the
population modelling of a monotonic dose-response relation.
*Bayesian Statistics 5, Proceedings of the Sixth Valencia International Meeting*, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M. (editors), Oxford University Press. - Wakefield, J.C. (1996).
The Bayesian approach to population pharmacokinetic models.
*Journal of the American Statistical Association*, 91, 61-76. - Wakefield, J.C. (1996). Bayesian individualization via sampling-based
methods.
*Journal of Pharmacokinetics and Biopharmaceutics*, 24, 103-131.### 1990-1995

- Wakefield, J.C. and Racine-Poon, A. (1995). An application
of Bayesian population pharmacokinetic/
pharmacodynamic models to
dose recommendation,
*Statistics in Medicine*, 14, 971-986. - Smith, A.F.M. and Wakefield, J.C. (1994). The hierarchical Bayesian
approach to population pharmacokinetic modelling.
*International Journal of Bio-Medical Computing*, 36, 35-42. - Wakefield, J.C. (1994).
An expected loss approach to the design of dosage regimens
via sampling-based methods.
*The Statistician*, 43, 13-29. - Wakefield, J.C., Smith, A.F.M., Racine-Poon, A. and Gelfand, A.E. (1994).
Bayesian analysis of linear and non-linear population models using
the Gibbs sampler.
*Applied Statistics*, 43, 201-221. - Wakefield, J. C., Gelfand, A. E. and Smith, A. F. M. (1991).
Efficient generation of random variates via the ratio-of-uniforms method.
*Statistics and Computing,*1, 129-133. - Wakefield, J. C., Skene, A. M., Smith, A. F. M. and Evett, I. W. (1991).
The evaluation of fibre transfer evidence in forensic science: a case
study in statistical modelling.
*Applied Statistics,*40, 461-476. - Skene, A. M., and Wakefield, J. C. (1990). Hierarchical models for multi-centre
binary response studies.
*Statistics in Medicine*, 9, 919-929.