Referreed Articles
Google scholar link to my papers:
here.
2015
 Akullian, A., Ng'eno, E., Matheson, A.I., Macharia, D., Leonard, C., Bigogo, G., Stewart, G., Walson, J., Wakefield, J. and Montgomery, J.M. (2015). Environmental transmission of typhoid fever in an urban slum. To appear in PLOS Neglected Tropical Diseases.
 Schaafsma, T., Wakefield, J., Hanisch, R., Bray, F., Schuz, J., Joy, E.J.M., Watts, M.J. and McCormack, V. (2015). Micronutrient intake and the African esphagael cancer belt  ecological insights. To appear in PLOS ONE.
 Psoter, K.J., De Roos, A.J., Wakefield, J., Mayer, J.Di., Bryan, M., Rosenfeld, M. (2015). Association of meteorologic and geographic factors and risk of initial Pseudomonas aeruginosa acquisition in young children with cystic fibrosis. Epidemiology and Infection. In Press.
 Koepke, A.A., Longini, I.M., Halloran, M.E., Wakefield. J. and Minin, V.N. (2015). Predictive modeling of cholera outbreaks in Bangladesh. Under revision for Annals of Applied Statistics.
 Chen, C., Wakefield, J., Self, S. and Rue, H. (2015). Bayesian Penalized Spline Models for the Analysis of SpatioTemporal Count Data. To appear in Statistics in Medicine.
 Kim, A. and Wakefield, J. (2015). Bayesian Method for Cluster Detection with Application to Five Cancer Sites in Puget Sound. To appear in Epidemiology.
 Mercer, L., Wakefield, J., Pantazis, A., Lutambi, A., Masanja, H. and Clark, S. (2015). Small Area Estimation of Child Mortality in the Absence of Vital Registration. To appear in Annals of Applied Statistics.
 Ross, M.E. and Wakefield, J. (2015). Bayesian hierarchical models for smoothing in twophase studies, with application to small area estimation. To appear in Journal of the Royal Statistical Society, Series A.
 Smith, T., Wakefield, J. and Dobra, A. (2015). Restricted covariance priors with application in spatial statistics. Bayesian Analysis.
Paper can be found here.
2014
 Andrie, J.M., Wakefield, J. and Akey, J.M. (2014). Heritable variation of mRNA decay rates in yeast. Genome Research, 24, 20002010.
 Chen, C., Wakefield, J. and Lumley, T. (2014). The use of sampling weights in Bayesian hierarchical models for small area estmation. Spatial and Spatiotemporal Epidemiology, published online.
 Akullian, A, Kohler, P., Kinuthia, J., Laserson, K., Mills, L.A., Okanda, J., Olilo, G., Ombok, M., Odhiambo, F., Rao, D., Wakefield, J. and JohnStewart, G. (2014). Geographic distribution of HIV stigma among women of childbearing age in rural Kenya. AIDS, 28, 16651672.
 Mercer, L., Wakefield, J., Chen, C. and Lumley, T. (2014). A Comparison of spatial smoothing weighting methods for small area estimation. Spatial Statistics. Published online.
 Connelly, C.F., Wakefield, J. and Akey, J.M. (2014). Evolution and genetic architecture of chromatin accessibility and function in yeast. PLoS Genetics, Published July 3, 2014.
 Psoter, K, Rosenfeld, M., DeRoos, A.J., Mayer, J.D. and Wakefield, J. (2014). Differential geographical risk of initial Pseudomonas aeruginosa acquisition in young U.S. children with cystic fibrosis. American Journal of Epidemiology, 179, 15031513.
 Wakefield, J.C., Skrivankova, V., Hsu, F.C., Sale, M. and Heagerty, P. (2014). Detecting signals in pharmacogenomic studies. The Pharmacogenomics Journal. Published online January, 2014.
 Glynn, A. and Wakefield, J. (2014). Alleviating ecological bias in Poisson models using optimal subsampling: The effects of Jim Crow on black illiteracy in the Robinson data". Sociological Methodology, 44, 159184.
2013
 Skelly, D.A., Merrihew, G.E., Riffle, M., Connelly, C.F., Kerr, E.O., Johansson, M., Jaschob, D., Graczyk, B., Shulman, N.J., Wakefield, J., Cooper, S.J., Field, S., Noble, W.S. Muller, E.G., Davis, T.N., Dunham, M.J., Maccoss, M.J. and Akey, J.M. (2013). Integrative phemomics reveals insight into the structure of phenotypic diversity in budding yeast. Genome Research, 23, 14961504.
 Psoter, K.J., de Roos, A.J, Wakefield, J., Mayer, J.D. and Rosenfeld, M. (2013). Season is associated with Pseudomonas aeruginosa acquisition in young children with cystic fibrosis. Clinical Microbiology and Infection. , 19, E483E489.
 Zheng, Z., Shen, J., Cox, C., Wakefield, J.C., Ehm, M.G., Nelson, M.R. and Weir, B.S. (2013). HIBAG  HLA genotype imputation with attribute bagging. The Pharmacogenomics Journal, published online May 2013.
 Shaddick G., Lee D. and Wakefield J. (2013). Ecological bias in studies of the shortterm effects of air pollution on health. International Journal of Applied Earth Observation and Geoinformation, 22, 6574.
 Wakefield, J. and Kim, A. (2013). A Bayesian model for cluster detection. Biostatistics, 14, 752765.
 Hoff, P. and Wakefield, J. (2013). A Bayesian sandwich estimator. To appear in Journal of Statistical Planning and Inference (as a discussion of Stephen Walker's "Bayesian inference with misspecified models").
 Ross, M.E. and Wakefield, J.C. (2013). Bayesian inference for twophase studies with categorical covariates. Biometrics, 69, 469477.
 Islami, F.,...,Wakefield, J. ... (2013). Smoking waterpipe, chewing nass, and prevalence of heart disease  A crosssectional analysis of baseline data from the Golestan cohort study, Iran. Heart , 99, 272278.
2012
 Fong, Y., Wakefield, J., De Rosa, S. and Frahm, N. (2012). A robust Bayesian random effects model for nonlinear calibration problems. Biometrics, 68, 11031112.
 Johansson, M.,...,Wakefield, J. and Mckay, J.D. (2012). Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4  the AdAPT method. PLoS One, 7, e36888.
 de Vocht, F., Cherry, N. and Wakefield, J (2012). A Bayesian mixture modeling approach for assessing the effects of correlated exposures in casecontrol studies. Journal of Exposure Science and Environmental Epidemiology, 22, 352360.
 Fong, Y., Wakefield, J. and Rice, K. (2012). An efficient Markov chain Monte Carlo method for mixture models by neighborhood pruning. Journal of Computational and Graphical Statistics, 21, 197216.
2011
 Skelly, D.A., Johansson, M., Madeoy, J., Wakefield, J. and Akey, J.M. (2011). A powerful and flexible statistical framework for testing hypotheses of allelespecific gene expression from RNASeq data. Genome Research, 21, 17281737. Paper can be accessed
here
 Wang, Y., Feng, Z., Yang, Y., Self, S., Gao, Y., Longini, I.M., Wakefield, J., Zhang, J., Wang, L., Chen, C., Yao, L., Stanaway, J.D., Wang, Z. and Yang, W. (2011). Hand, foot and mouth disease in China: patterns of spread and transmissibility during 20082009. Epidemiology, 22, 781792.
 Wakefield, J., Haneuse, S., Dobra, A. and Teeple, E. (2011). Bayes computation for ecological inference. Statistics in Medicine, 30, 13811396.
2010
 Ross, M.E., Wakefield, J., Davis, S. and De Roos, A.J (2010). Spatial clustering of myelodysplastic syndromes (MDS) in the SeattlePuget sound region of Washington State. Cancer Causes Control, 21, 829838.
 Wakefield, J. (2010). Bayesian methods for examining HardyWeinberg equilibrium.
Biometrics, 66, 257265.
 Glynn, A. and Wakefield (2010). Ecological inference in the social sciences. Statistical Methodology, 7, 307322.
 Fong, Y., Rue, H. and Wakefield, J. (2010). Bayesian inference for generalized linear mixed models. Biostatistics, 11, 397412.
 Fong, Y., Wakefield, J, and Rice, K. (2010). Bayesian mixture modeling using a hybrid sampler with application to protein subfamily identification. Biostatistics, 11, 1833.
 Wakefield, J., de Vocht, F. and Hung, R.J. (2010). Bayesian mixture modeling of geneenvironment and genegene interactions. Genetic Epidemiology, 34, 1625.
2009
 Islami, F., Malekshah, A.F., Kimiagar, M., Pourshams, A., Wakefield, J., et al. (2009). Patterns of food and nutrient consumption in Northern Iran, a highrisk area for esophageal cancer, Nutrition and Cancer, 61, 475483.
 Wakefield, J. (2009). Multilevel modelling, the ecologic fallacy, and hybrid study designs,
International Journal of Epidemiology, 38, 330336. Illiteracy data Paper WinBUGS code
 Islami, F., Kamangar, F., Nasrollahzadeh, D., Aghcheli, K., Sotoudeh, M., AbediArdekani, B., Merat, S., NasseriMoghaddam, S., Semnani, S., Sepehr, A., Wakefield, J., et al. (2009). Socioeconomic status and oesophageal cancer: results from a populationbased casecontrol study in a highrisk area.
International Journal of Epidemiology, 38, 978988.
 Wakefield, J. (2009). Bayes factors for genomewide association studies: comparison with pvalues. Genetic Epidemiology, 33, 7986.
2008
 Salway, R.E. and Wakefield, J. (2008). Gamma generalized linear models for pharmacokinetic data. Biometrics, 64, 620626.
 Wakefield, J. (2008). Ecologic studies revisited. Annual Review of Public Health 29, 7590. annrev08.pdf
 Wakefield, J. (2008). Reporting and interpretation in genomewide association studies. International Journal of Epidemiology. wakefieldIJE.pdf 37, 641653.
 Wakefield, J. and Haneuse, S. (2008). Overcoming ecological bias using the twophase study design. American Journal of Epidemiology, 167, 908916 wakefieldhaneuseAJE.pdf

McKay, J.D. Hashibe, M, Hung, R.J., Wakefield, J., et al. (2008).
Sequence Variants of NAT1 and NAT2 and Other Xenometabolic Genes and Risk of Lung and Aerodigestive Tract Cancers in Central Europe. Cancer Epidemiology and Biomarkers, 17, 141147.
 Haneuse, S. and Wakefield, J. (2008). The combination of ecological and casecontrol data. Journal of the Royal Statistical Society, Series B, 70, 7393 haneusewakefieldRSSB.pdf.
 Glynn, A., Wakefield, J., Handcock, M. and Richardson, T.S. (2008). Alleviating linear ecological bias and optimal design with subsample data. Journal of the Royal Statistical Society, Series A 171, 179202. glynnetalRSSA.pdf.
 Li, S., Wakefield, J. and Self, S.G. (2008). A Transdimensional Bayesian model for pattern recognition in DNA sequence. Biostatistics, 9, 668685.
 Salway, R. and Wakefield, J. (2007). A hybrid model for reducing ecological bias. Biostatistics. 9, 117. Paper can be found here.
 Haneuse, S. and Wakefield, J. (2007). Geographicbased ecological correlation studies using supplemental casecontrol data. Statistics in Medicine, 27, 864887.
2007
 Wakefield, J. (2007). A Bayesian measure of the probability of false discovery in genetic
epidemiology studies. American Journal of Human Genetics, 81, 208227
Paper can be found here.
 Elliott, P., Shaddick, G., Wakefield, J., de Hoogh, C. and Briggs, D.J. (2007). Longterm associations of outdoor air pollution with mortality in Great Britain. Thorax, 62, 10881094. thorax2007.pdf
 Haneuse, S., Wakefield, J. and Sheppard, L. (2007). The interpretation of exposure effect estimates in chronic air pollution studies. Statistics in Medicine, 26, 31723187. Paper can be found
here.
 Haneuse, S. and Wakefield, J. (2007). Hierarchical models for combining
ecological and casecontrol data. Biometrics, 63, 128136.
Paper can be found here.
 Wakefield, J. (2007). Disease mapping and spatial regression with count data. Biostatistics, 8, 158183. Paper can be found here.
2006
 Wakefield, J. and Shaddick, G. (2006). Healthexposure modelling and the ecological fallacy. Biostatistics, 7, 438455. Paper can be found here.
 Zhou, C. and Wakefield, J. (2006). A Bayesian hierarchical mixture model
for curve partitioning. Biometrics, 62, 515526, Bugs Code
 Gordian, M.E., Haneuse, S. and Wakefield, J. (2006). An investigation of the association between traffic exposure and the diagnosis of asthma.
Journal of Exposure Science and Environmental Epidemiology, 16, 4955.
 Hawkins, N., Self, S. and Wakefield, J (2006). The automated counting of spots for the ELISpot assay. Journal of Immunological Methods, 316, 5258.Paper can be found here.
2005
 Whitaker, H., Best. N., Nieuwenhuijsen, M., Wakefield, J., Fawell, J. and Elliott, P. (2005). Modelling exposure to disinfection byproducts in drinking water for an epidemiological study of adverse birth outcomes. Journal of Exposure Analysis and Environmental Epidemiology, 15, 138146.
 Dabney, A. and Wakefield, J.C. (2005). Issues in the mapping of two diseases.
Statistical Methods in Medical Research, 14, 83112.alan.pdf
 Salway, R. and Wakefield, J.C. (2005). Sources of bias in ecological studies of nonrare events. Environmental and Ecological Statistics, 12,
321347.eesruth.pdf
2004
 Bottle, R.A. and Wakefield, J.C. (2004). Statistical issues in
relation to the modeling of respiratory disease in relation to
cokeworks. Statistics in Medicine, 23, 31393158.
alex.pdf
 Wakefield, J. (2004). Ecological inference for 2x2 tables (with discussion).
Journal of the Royal Statistical Society, Series A, 167, 385445. read.pdf.
Data
can be found
here.
 Wakefield, J. (2004). A critique of statistical aspects of ecological
studies in spatial epidemiology. Environmental and Ecological Statistics,
11, 3154. ees.pdf
2003
 Wakefield, J., Zhou, C. and Self, S. (2003). Modelling gene expression over
time: curve clustering with informative prior distributions.
Bayesian Statistics 7, Proceedings of the Seventh
Valencia International
Meeting, p. 721732, Bernardo, J.M., Bayarri, M.J., Berger, J.O., Dawid, A.P., Heckerman, Smith, A.F.M., West, M.
(editors), Oxford University Press. newval.pdf
 Wakefield, J. (2003). Sensitivity analyses for ecological regression. Biometrics, 59, 917. biometrics.pdf
 Hickman, M., Madden, P., Henry, J., Baker, A., Wallace, C., Wakefield, J., Stimson, G. and Elliott, P. (2003). Trends in drug overdose deaths in England and Wales 199398: methadone does not kill more people than heroin. Addiction, 98, 41425.
2002
 Guthrie, K.A., Sheppard, L. and Wakefield, J. (2002). A hierarchical aggregate data model with spatially correlated disease rates. Biometrics, 58, 898905. biomkath.pdf
 Kelsall, J.E. and Wakefield, J.C. (2002).
Modeling spatial variation in disease risk: A geostatistical approach. Journal of the American Statistical Association, 97, 692701.
 Shaddick, G. and Wakefield, J. (2002). Modelling multivariate
pollutant data at multiple sites. Applied Statistics, 51, 351372.
appliedstats.pdf
 Lunn, D.J., Best, N., Thomas, A., Wakefield, J. and Spiegelhalter, D.
(2002).
Bayesian analysis of population PK/PD models: General concepts and software.
Journal of Pharmacokinetics and Pharmacodynamics, 29, 271307.
 Jarup, L., Toledano, M.B., Best, N., Wakefield, J., Elliott P. (2002). Geographical
epidemiology of prostate cancer in Great Britain. International Journal of Epidemiology, 97, 695699.
 Jarup, L., Briggs, D., de Hoogh, C., Morris, S., Hurt, C., Lewin, A., Maitland, I., Richardson, S., Wakefield, J., Elliott, P. (2002). Cancer risks in populations living near landfill sites in Great Britain, British Journal
of Cancer, 86, 17321736.
2001
 Lunn, D.J., Wakefield, J.C. and Racine, A. (2001). Cumulative logit models for
ordinal data: a case study involving allergic rhinitis severity scores.
Statistics in Medicine, 20, 22612285.
 Elliott, P., Briggs,D., Morris, S., de Hoogh, C., Hurt, C., Jensen, T.,
Maitland, I., Richardson, S., Wakefield, J. and Jarup, L. (2001)
Risk of adverse birth outcomes in populations living near landfill sites.
British Medical Journal, 323, 363368.
 Bennett, J.E. and Wakefield, J.C. (2001) Errorsinvariables in joint
population pharmacokinetic/pharmacodynamic modeling. Biometrics, 57, 803812.
 Aylin, P., Bottle, A., Wakefield, J., Jarup, L., Elliott, P. (2001). Proximity to coke works
and hospital admissions for respiratory and cardiovascular disease in
England and Wales. Thorax, 56, 228233.
 Wakefield, J.C. and Morris, S.E. (2001).
The Bayesian modeling of disease risk in relation to a point source.
Journal of the American Statistical Association, 96, 7791.
 Elliott, P. and Wakefield, J. (2001). Disease clusters: should they be investigated, and if so, when and how? Journal of the
Royal Statistical Society, Series A, 164, 312.
 Wakefield, J. and Salway, R. (2001). A statistical framework for
ecological and aggregate studies. Journal of the
Royal Statistical Society, Series A, 164, 119137.
 Aylin, P., Morris, S., Wakefield, J., Grossinho, A., Jarup, L., Elliott, P.
(2001).
Temperature, housing, deprivation and their relationship to excess winter
mortality in Great Britain, 19861996. International Journal of Epidemiology, 30, 11001108.
 Best, N., Cockings, S., Bennett, J., Wakefield, J. and Elliott,
P. (2001). Ecological regression analysis of environmental benzene
exposure and childhood leukemia: sensitivity to data inaccuracies,
geographical scale and ecological bias. Journal of the Royal
Statistical Society, Series A, 164, 155174.
 Toledano, M., Jarup, L., Best, N., Wakefield, J.C, Elliott
P. (2001). Spatial and temporal trends of testicular cancer in Great
Britain. British Journal of Cancer, 84,
14821487.
2000
 Pascutto, C., Wakefield, J., Best, N., Bernardinelli, L., Elliott, P.,
Richardson, S. and Staines, A. (2000). Statistical issues in the analysis of disease mapping data. Statistics in Medicine, 19, 24932519.
 Wakefield, J.C. and Rahman, N. (2000). The combination of population
pharmacokinetic studies. Biometrics, 56, 263270.
 Morris, S.E., Sale, R., Wakefield, J.C., Falconer, S., Elliott, P. and
Boucher, B.J. (2000).
Hospital admissions for asthma and chronic obstructive airways disease in
east London hospitals and proximity to major roads.
Journal of Epidemiology and Community Health, 54, 7576.
 Elliott, P., Arnold, R., Cockings, S., Eaton, N., Jarup, L., Jones, J., Quinn, M.,
Rosato, M., Thornton, I., Toledano, M., Tristan, E., Wakefield, J. (2000). Risk
of mortality, cancer incidence and stroke in a population potentially
exposed to cadmium. Occupational and Environmental Medicine,
57, 9497.
 Diggle, P.J., Morris, S.E. and Wakefield, J.C. (2000). Point source modelling using
matched casecontrol data.
Biostatistics, 1, 89105.
1999
 Pauler, D.K., Wakefield, J.C. and Kass, R.E. (1999).
Bayes factors for variance component models.
Journal of the American Statistical Association,
94, 12421253.
 Wakefield, J.C. and Morris, S.E. (1999).
An application of spatial errorsinvariables modelling: investigating the
relationship between ischaemic heart disease and water constituents.
Bayesian Statistics 6, Proceedings of the Sixth
Valencia International
Meeting, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M.
(editors), p. 657684, Oxford University Press.
 Sheiner, L. and Wakefield, J. (1999),
Population modelling in drug development,
Statistical Methods in Medical Research, 8, 183193.
 Rahman, N.J., Wakefield, J.C., Stephens, D.A. and Falcoz, C. (1999),
Parameter estimation, model adequacy and assessment of dose proportionality
for pivotal pharmacokinetic study,
Statistical Methods in Medical Research, 8, 195216.
 Best, N.G. and Wakefield, J.C. (1999). Accounting for inaccuracies
in populations counts and case registration in cancer mapping studies.
Journal of the Royal Statistical Society, Series A, 162,
363382.
 Wakefield, J.C. and Elliott, P. (1999). Issues in the statistical
analysis of smallarea health data.
Statistics in Medicine, 18, 23772399.
 Aylin P, Maheswaran R, Wakefield J, Cockings S, Jarup L, Arnold R,
Wheeler G, Elliott P. (1999). A national facility for small area
disease mapping and rapid initial assessment of apparent disease
clusters around a point source: the UK Small Area Health Statistics
Unit. Journal of Public Health Medicine, 21, 28998.
 Damien, P., Wakefield, J.C. and Walker, S.G. (1999).
Gibbs sampling for Bayesian nonconjugate and hierarchical models
using auxiliary variables.
Journal of the Royal Statistical Society, Series B, 61, 331344.
 Maheswaran, R., Morris, S.E., Falconer, S., Grossinho,
A., Wakefield, J.C. and Elliott, P. (1999).
Magnesium in drinking water supplies and mortality from acute
myocardial infarction in North West England. Heart, 82,
455460.
1998
 RacinePoon, A. and Wakefield, J.C. (1998).
Statistical methods for population pharmacokinetic modelling,
Statistical Methods in Medical Research, 7, 6384.
 Walker, S.G. and Wakefield, J.C. (1998). Population models with a nonparametric random coefficient distribution. Sankhya, Series B, 60, 196212.
 Wakefield, J.C. (1998). The United Kingdom Small Area Health Statistics Unit.
Journal of Japan Society for Atmospheric Environment, 33, A60A66.
1997
 Wakefield, J.C. and Walker, S.G. (1997). Bayesian nonparametric population
models: formulation and comparison with likelihood approaches.
Journal of Pharmacokinetics and Biopharmaceutics,
25, 235253.
 Bennett, J.E., Wakefield, J.C. and Lacey, L.F. (1997). Modelling of
trough plasma bismuth concentrations. Journal of
Pharmacokinetics and Biopharmaceutics, 25, 79106.
 Wakefield, J.C. and Walker, S.G. (1997). A population approach to initial dose
selection. Statistics in Medicine, 16, 11351149.
1996
 Walker, S.G. and Wakefield, J.C. (1996). Bayesian approaches to the
population modelling of a monotonic doseresponse relation.
Bayesian Statistics 5, Proceedings of the Sixth
Valencia International
Meeting, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M.
(editors), Oxford University Press.
 Wakefield, J.C. (1996).
The Bayesian approach to population pharmacokinetic models.
Journal of
the American Statistical Association, 91, 6176.
 Wakefield, J.C. (1996). Bayesian individualization via samplingbased
methods. Journal of Pharmacokinetics and Biopharmaceutics,
24, 103131.
19901995
 Wakefield, J.C. and RacinePoon, A. (1995). An application
of Bayesian population pharmacokinetic/
pharmacodynamic models to
dose recommendation, Statistics in Medicine, 14,
971986.
 Smith, A.F.M. and Wakefield, J.C. (1994). The hierarchical Bayesian
approach to population pharmacokinetic modelling.
International Journal of BioMedical Computing, 36, 3542.
 Wakefield, J.C. (1994).
An expected loss approach to the design of dosage regimens
via samplingbased methods. The Statistician, 43, 1329.
 Wakefield, J.C., Smith, A.F.M., RacinePoon, A. and Gelfand, A.E. (1994).
Bayesian analysis of linear and nonlinear population models using
the Gibbs sampler. Applied Statistics, 43, 201221.
 Wakefield, J. C., Gelfand, A. E. and Smith, A. F. M. (1991).
Efficient generation of random variates via the ratioofuniforms method.
Statistics and Computing,
1,
129133.
 Wakefield, J. C., Skene, A. M., Smith, A. F. M. and Evett, I. W. (1991).
The evaluation of fibre transfer evidence in forensic science: a case
study in statistical modelling.
Applied Statistics,
40,
461476.
 Skene, A. M., and Wakefield, J. C. (1990). Hierarchical models for multicentre
binary response studies.
Statistics in Medicine, 9,
919929.