Referreed Articles

    2013

  1. Psoter, K.J., de Roos, A.J, Wakefield, J., Mayer, J.D. and Rosenfeld, M. (2013). Season is associated with Pseudomonas aeruginosa acquisition in young children with cystic fibrosis. To appear in Clinical Microbiology and Infection.
  2. Zheng, Z., Shen, J., Cox, C., Wakefield, J.C., Ehm, M.G., Nelson, M.R. and Weir, B.S. (2013). HIBAG - HLA genotype imputation with attribute bagging. To appear in The Pharmacogenomics Journal.
  3. Shaddick G., Lee D. and Wakefield J. (2013). Ecological bias in studies of the short-term effects of air pollution on health. International Journal of Applied Earth Observation and Geoinformation, 22, 65--74.
  4. Wakefield, J. and Kim, A. (2013). A Bayesian model for cluster detection. To appear in Biostatistics.
  5. Hoff, P. and Wakefield, J. (2013). A Bayesian sandwich estimator. To appear in Journal of Statistical Planning and Inference (as a discussion of Stephen Walker's "Bayesian inference with misspecified models").
  6. Ross, M.E. and Wakefield, J.C. (2013). Bayesian inference for two-phase studies with categorical covariates. To appear in Biometrics.
  7. Islami, F.,...,Wakefield, J. ... (2013). Smoking water-pipe, chewing nass, and prevalence of heart disease -- A cross-sectional analysis of baseline data from the Golestan cohort study, Iran. Heart , 99, 272--278.

    2012

  8. Fong, Y., Wakefield, J., De Rosa, S. and Frahm, N. (2012). A robust Bayesian random effects model for nonlinear calibration problems. Biometrics, 68, 1103--1112.
  9. Johansson, M.,...,Wakefield, J. and Mckay, J.D. (2012). Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4 - the AdAPT method. PLoS One, 7, e36888.
  10. de Vocht, F., Cherry, N. and Wakefield, J (2012). A Bayesian mixture modeling approach for assessing the effects of correlated exposures in case-control studies. Journal of Exposure Science and Environmental Epidemiology, 22, 352-360.
  11. Fong, Y., Wakefield, J. and Rice, K. (2012). An efficient Markov chain Monte Carlo method for mixture models by neighborhood pruning. Journal of Computational and Graphical Statistics, 21, 197-216.

    2011

  12. Skelly, D.A., Johansson, M., Madeoy, J., Wakefield, J. and Akey, J.M. (2011). A powerful and flexible statistical framework for testing hypotheses of allele-specific gene expression from RNA-Seq data. Genome Research, 21, 1728-1737. Paper can be accessed here
  13. Wang, Y., Feng, Z., Yang, Y., Self, S., Gao, Y., Longini, I.M., Wakefield, J., Zhang, J., Wang, L., Chen, C., Yao, L., Stanaway, J.D., Wang, Z. and Yang, W. (2011). Hand, foot and mouth disease in China: patterns of spread and transmissibility during 2008-2009. Epidemiology, 22, 781-792.
  14. Wakefield, J., Haneuse, S., Dobra, A. and Teeple, E. (2011). Bayes computation for ecological inference. Statistics in Medicine, 30, 1381-1396.

    2010

  15. Ross, M.E., Wakefield, J., Davis, S. and De Roos, A.J (2010). Spatial clustering of myelodysplastic syndromes (MDS) in the Seattle-Puget sound region of Washington State. Cancer Causes Control, 21, 829-838.
  16. Wakefield, J. (2010). Bayesian methods for examining Hardy-Weinberg equilibrium. Biometrics, 66, 257-265.
  17. Glynn, A. and Wakefield (2010). Ecological inference in the social sciences. Statistical Methodology, 7, 307-322.
  18. Fong, Y., Rue, H. and Wakefield, J. (2010). Bayesian inference for generalized linear mixed models. Biostatistics, 11, 397-412.
  19. Fong, Y., Wakefield, J, and Rice, K. (2010). Bayesian mixture modeling using a hybrid sampler with application to protein subfamily identification. Biostatistics, 11, 18-33.
  20. Wakefield, J., de Vocht, F. and Hung, R.J. (2010). Bayesian mixture modeling of gene-environment and gene-gene interactions. Genetic Epidemiology, 34, 16-25.

    2009

  21. Islami, F., Malekshah, A.F., Kimiagar, M., Pourshams, A., Wakefield, J., et al. (2009). Patterns of food and nutrient consumption in Northern Iran, a high-risk area for esophageal cancer, Nutrition and Cancer, 61, 475-483.
  22. Wakefield, J. (2009). Multi-level modelling, the ecologic fallacy, and hybrid study designs, International Journal of Epidemiology, 38, 330-336. Illiteracy data Paper WinBUGS code
  23. Islami, F., Kamangar, F., Nasrollahzadeh, D., Aghcheli, K., Sotoudeh, M., Abedi-Ardekani, B., Merat, S., Nasseri-Moghaddam, S., Semnani, S., Sepehr, A., Wakefield, J., et al. (2009). Socio-economic status and oesophageal cancer: results from a population-based case-control study in a high-risk area. International Journal of Epidemiology, 38, 978-988.
  24. Wakefield, J. (2009). Bayes factors for genome-wide association studies: comparison with p-values. Genetic Epidemiology, 33, 79-86.

    2008

  25. Salway, R.E. and Wakefield, J. (2008). Gamma generalized linear models for pharmacokinetic data. Biometrics, 64, 620-626.
  26. Wakefield, J. (2008). Ecologic studies revisited. Annual Review of Public Health 29, 75-90. annrev08.pdf
  27. Wakefield, J. (2008). Reporting and interpretation in genome-wide association studies. International Journal of Epidemiology. wakefieldIJE.pdf 37, 641-653.
  28. Wakefield, J. and Haneuse, S. (2008). Overcoming ecological bias using the two-phase study design. American Journal of Epidemiology, 167, 908-916 wakefieldhaneuseAJE.pdf
  29. McKay, J.D. Hashibe, M, Hung, R.J., Wakefield, J., et al. (2008). Sequence Variants of NAT1 and NAT2 and Other Xenometabolic Genes and Risk of Lung and Aerodigestive Tract Cancers in Central Europe. Cancer Epidemiology and Biomarkers, 17, 141-147.
  30. Haneuse, S. and Wakefield, J. (2008). The combination of ecological and case-control data. Journal of the Royal Statistical Society, Series B, 70, 73-93 haneusewakefieldRSSB.pdf.
  31. Glynn, A., Wakefield, J., Handcock, M. and Richardson, T.S. (2008). Alleviating linear ecological bias and optimal design with subsample data. Journal of the Royal Statistical Society, Series A 171, 179-202. glynnetalRSSA.pdf.
  32. Li, S., Wakefield, J. and Self, S.G. (2008). A Trans-dimensional Bayesian model for pattern recognition in DNA sequence. Biostatistics, 9, 668-685.
  33. Salway, R. and Wakefield, J. (2007). A hybrid model for reducing ecological bias. Biostatistics. 9, 1-17. Paper can be found here.
  34. Haneuse, S. and Wakefield, J. (2007). Geographic-based ecological correlation studies using supplemental case-control data. Statistics in Medicine, 27, 864-887.

    2007

  35. Wakefield, J. (2007). A Bayesian measure of the probability of false discovery in genetic epidemiology studies. American Journal of Human Genetics, 81, 208-227 Paper can be found here.
  36. Elliott, P., Shaddick, G., Wakefield, J., de Hoogh, C. and Briggs, D.J. (2007). Long-term associations of outdoor air pollution with mortality in Great Britain. Thorax, 62, 1088-1094. thorax2007.pdf
  37. Haneuse, S., Wakefield, J. and Sheppard, L. (2007). The interpretation of exposure effect estimates in chronic air pollution studies. Statistics in Medicine, 26, 3172-3187. Paper can be found here.
  38. Haneuse, S. and Wakefield, J. (2007). Hierarchical models for combining ecological and case-control data. Biometrics, 63, 128-136. Paper can be found here.
  39. Wakefield, J. (2007). Disease mapping and spatial regression with count data. Biostatistics, 8, 158-183. Paper can be found here.

    2006

  40. Wakefield, J. and Shaddick, G. (2006). Health-exposure modelling and the ecological fallacy. Biostatistics, 7, 438-455. Paper can be found here.
  41. Zhou, C. and Wakefield, J. (2006). A Bayesian hierarchical mixture model for curve partitioning. Biometrics, 62, 515-526, Bugs Code
  42. Gordian, M.E., Haneuse, S. and Wakefield, J. (2006). An investigation of the association between traffic exposure and the diagnosis of asthma. Journal of Exposure Science and Environmental Epidemiology, 16, 49-55.
  43. Hawkins, N., Self, S. and Wakefield, J (2006). The automated counting of spots for the ELISpot assay. Journal of Immunological Methods, 316, 52-58. Paper can be found here.

    2005

  44. Whitaker, H., Best. N., Nieuwenhuijsen, M., Wakefield, J., Fawell, J. and Elliott, P. (2005). Modelling exposure to disinfection by-products in drinking water for an epidemiological study of adverse birth outcomes. Journal of Exposure Analysis and Environmental Epidemiology, 15, 138-146.
  45. Dabney, A. and Wakefield, J.C. (2005). Issues in the mapping of two diseases. Statistical Methods in Medical Research, 14, 83-112.alan.pdf
  46. Salway, R. and Wakefield, J.C. (2005). Sources of bias in ecological studies of non-rare events. Environmental and Ecological Statistics, 12, 321-347.eesruth.pdf

    2004

  47. Bottle, R.A. and Wakefield, J.C. (2004). Statistical issues in relation to the modeling of respiratory disease in relation to cokeworks. Statistics in Medicine, 23, 3139-3158. alex.pdf
  48. Wakefield, J. (2004). Ecological inference for 2x2 tables (with discussion). Journal of the Royal Statistical Society, Series A, 167, 385-445. read.pdf. Data can be found here.
  49. Wakefield, J. (2004). A critique of statistical aspects of ecological studies in spatial epidemiology. Environmental and Ecological Statistics, 11, 31-54. ees.pdf

    2003

  50. Wakefield, J., Zhou, C. and Self, S. (2003). Modelling gene expression over time: curve clustering with informative prior distributions. Bayesian Statistics 7, Proceedings of the Seventh Valencia International Meeting, p. 721-732, Bernardo, J.M., Bayarri, M.J., Berger, J.O., Dawid, A.P., Heckerman, Smith, A.F.M., West, M. (editors), Oxford University Press. newval.pdf
  51. Wakefield, J. (2003). Sensitivity analyses for ecological regression. Biometrics, 59, 9-17. biometrics.pdf
  52. Hickman, M., Madden, P., Henry, J., Baker, A., Wallace, C., Wakefield, J., Stimson, G. and Elliott, P. (2003). Trends in drug overdose deaths in England and Wales 1993-98: methadone does not kill more people than heroin. Addiction, 98, 41-425.

    2002

  53. Guthrie, K.A., Sheppard, L. and Wakefield, J. (2002). A hierarchical aggregate data model with spatially correlated disease rates. Biometrics, 58, 898-905. biomkath.pdf
  54. Kelsall, J.E. and Wakefield, J.C. (2002). Modeling spatial variation in disease risk: A geostatistical approach. Journal of the American Statistical Association, 97, 692-701.
  55. Shaddick, G. and Wakefield, J. (2002). Modelling multivariate pollutant data at multiple sites. Applied Statistics, 51, 351-372. appliedstats.pdf
  56. Lunn, D.J., Best, N., Thomas, A., Wakefield, J. and Spiegelhalter, D. (2002). Bayesian analysis of population PK/PD models: General concepts and software. Journal of Pharmacokinetics and Pharmacodynamics, 29, 271-307.
  57. Jarup, L., Toledano, M.B., Best, N., Wakefield, J., Elliott P. (2002). Geographical epidemiology of prostate cancer in Great Britain. International Journal of Epidemiology, 97, 695-699.
  58. Jarup, L., Briggs, D., de Hoogh, C., Morris, S., Hurt, C., Lewin, A., Maitland, I., Richardson, S., Wakefield, J., Elliott, P. (2002). Cancer risks in populations living near landfill sites in Great Britain, British Journal of Cancer, 86, 1732-1736.

    2001

  59. Lunn, D.J., Wakefield, J.C. and Racine, A. (2001). Cumulative logit models for ordinal data: a case study involving allergic rhinitis severity scores. Statistics in Medicine, 20, 2261-2285.
  60. Elliott, P., Briggs,D., Morris, S., de Hoogh, C., Hurt, C., Jensen, T., Maitland, I., Richardson, S., Wakefield, J. and Jarup, L. (2001) Risk of adverse birth outcomes in populations living near landfill sites. British Medical Journal, 323, 363-368.
  61. Bennett, J.E. and Wakefield, J.C. (2001) Errors-in-variables in joint population pharmacokinetic/pharmacodynamic modeling. Biometrics, 57, 803-812.
  62. Aylin, P., Bottle, A., Wakefield, J., Jarup, L., Elliott, P. (2001). Proximity to coke works and hospital admissions for respiratory and cardiovascular disease in England and Wales. Thorax, 56, 228-233.
  63. Wakefield, J.C. and Morris, S.E. (2001). The Bayesian modeling of disease risk in relation to a point source. Journal of the American Statistical Association, 96, 77-91.
  64. Elliott, P. and Wakefield, J. (2001). Disease clusters: should they be investigated, and if so, when and how? Journal of the Royal Statistical Society, Series A, 164, 3-12.
  65. Wakefield, J. and Salway, R. (2001). A statistical framework for ecological and aggregate studies. Journal of the Royal Statistical Society, Series A, 164, 119-137.
  66. Aylin, P., Morris, S., Wakefield, J., Grossinho, A., Jarup, L., Elliott, P. (2001). Temperature, housing, deprivation and their relationship to excess winter mortality in Great Britain, 1986-1996. International Journal of Epidemiology, 30, 1100-1108.
  67. Best, N., Cockings, S., Bennett, J., Wakefield, J. and Elliott, P. (2001). Ecological regression analysis of environmental benzene exposure and childhood leukemia: sensitivity to data inaccuracies, geographical scale and ecological bias. Journal of the Royal Statistical Society, Series A, 164, 155-174.
  68. Toledano, M., Jarup, L., Best, N., Wakefield, J.C, Elliott P. (2001). Spatial and temporal trends of testicular cancer in Great Britain. British Journal of Cancer, 84, 1482-1487.

    2000

  69. Pascutto, C., Wakefield, J., Best, N., Bernardinelli, L., Elliott, P., Richardson, S. and Staines, A. (2000). Statistical issues in the analysis of disease mapping data. Statistics in Medicine, 19, 2493-2519.
  70. Wakefield, J.C. and Rahman, N. (2000). The combination of population pharmacokinetic studies. Biometrics, 56, 263-270.
  71. Morris, S.E., Sale, R., Wakefield, J.C., Falconer, S., Elliott, P. and Boucher, B.J. (2000). Hospital admissions for asthma and chronic obstructive airways disease in east London hospitals and proximity to major roads. Journal of Epidemiology and Community Health, 54, 75-76.
  72. Elliott, P., Arnold, R., Cockings, S., Eaton, N., Jarup, L., Jones, J., Quinn, M., Rosato, M., Thornton, I., Toledano, M., Tristan, E., Wakefield, J. (2000). Risk of mortality, cancer incidence and stroke in a population potentially exposed to cadmium. Occupational and Environmental Medicine, 57, 94-97.
  73. Diggle, P.J., Morris, S.E. and Wakefield, J.C. (2000). Point source modelling using matched case-control data. Biostatistics, 1, 89-105.

    1999

  74. Pauler, D.K., Wakefield, J.C. and Kass, R.E. (1999). Bayes factors for variance component models. Journal of the American Statistical Association, 94, 1242-1253.
  75. Wakefield, J.C. and Morris, S.E. (1999). An application of spatial errors-in-variables modelling: investigating the relationship between ischaemic heart disease and water constituents. Bayesian Statistics 6, Proceedings of the Sixth Valencia International Meeting, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M. (editors), p. 657-684, Oxford University Press.
  76. Sheiner, L. and Wakefield, J. (1999), Population modelling in drug development, Statistical Methods in Medical Research, 8, 183-193.
  77. Rahman, N.J., Wakefield, J.C., Stephens, D.A. and Falcoz, C. (1999), Parameter estimation, model adequacy and assessment of dose proportionality for pivotal pharmacokinetic study, Statistical Methods in Medical Research, 8, 195-216.
  78. Best, N.G. and Wakefield, J.C. (1999). Accounting for inaccuracies in populations counts and case registration in cancer mapping studies. Journal of the Royal Statistical Society, Series A, 162, 363-382.
  79. Wakefield, J.C. and Elliott, P. (1999). Issues in the statistical analysis of small-area health data. Statistics in Medicine, 18, 2377-2399.
  80. Aylin P, Maheswaran R, Wakefield J, Cockings S, Jarup L, Arnold R, Wheeler G, Elliott P. (1999). A national facility for small area disease mapping and rapid initial assessment of apparent disease clusters around a point source: the UK Small Area Health Statistics Unit. Journal of Public Health Medicine, 21, 289-98.
  81. Damien, P., Wakefield, J.C. and Walker, S.G. (1999). Gibbs sampling for Bayesian nonconjugate and hierarchical models using auxiliary variables. Journal of the Royal Statistical Society, Series B, 61, 331-344.
  82. Maheswaran, R., Morris, S.E., Falconer, S., Grossinho, A., Wakefield, J.C. and Elliott, P. (1999). Magnesium in drinking water supplies and mortality from acute myocardial infarction in North West England. Heart, 82, 455-460.

    1998

  83. Racine-Poon, A. and Wakefield, J.C. (1998). Statistical methods for population pharmacokinetic modelling, Statistical Methods in Medical Research, 7, 63-84.
  84. Walker, S.G. and Wakefield, J.C. (1998). Population models with a nonparametric random coefficient distribution. Sankhya, Series B, 60, 196-212.
  85. Wakefield, J.C. (1998). The United Kingdom Small Area Health Statistics Unit. Journal of Japan Society for Atmospheric Environment, 33, A60-A66.

    1997

  86. Wakefield, J.C. and Walker, S.G. (1997). Bayesian nonparametric population models: formulation and comparison with likelihood approaches. Journal of Pharmacokinetics and Biopharmaceutics, 25, 235-253.
  87. Bennett, J.E., Wakefield, J.C. and Lacey, L.F. (1997). Modelling of trough plasma bismuth concentrations. Journal of Pharmacokinetics and Biopharmaceutics, 25, 79-106.
  88. Wakefield, J.C. and Walker, S.G. (1997). A population approach to initial dose selection. Statistics in Medicine, 16, 1135-1149.

    1996

  89. Walker, S.G. and Wakefield, J.C. (1996). Bayesian approaches to the population modelling of a monotonic dose-response relation. Bayesian Statistics 5, Proceedings of the Sixth Valencia International Meeting, Bernardo, J.M., Berger, J.O., Dawid, A.P. and Smith, A.F.M. (editors), Oxford University Press.
  90. Wakefield, J.C. (1996). The Bayesian approach to population pharmacokinetic models. Journal of the American Statistical Association, 91, 61-76.
  91. Wakefield, J.C. (1996). Bayesian individualization via sampling-based methods. Journal of Pharmacokinetics and Biopharmaceutics, 24, 103-131.

    1990-1995

  92. Wakefield, J.C. and Racine-Poon, A. (1995). An application of Bayesian population pharmacokinetic/ pharmacodynamic models to dose recommendation, Statistics in Medicine, 14, 971-986.
  93. Smith, A.F.M. and Wakefield, J.C. (1994). The hierarchical Bayesian approach to population pharmacokinetic modelling. International Journal of Bio-Medical Computing, 36, 35-42.
  94. Wakefield, J.C. (1994). An expected loss approach to the design of dosage regimens via sampling-based methods. The Statistician, 43, 13-29.
  95. Wakefield, J.C., Smith, A.F.M., Racine-Poon, A. and Gelfand, A.E. (1994). Bayesian analysis of linear and non-linear population models using the Gibbs sampler. Applied Statistics, 43, 201-221.
  96. Wakefield, J. C., Gelfand, A. E. and Smith, A. F. M. (1991). Efficient generation of random variates via the ratio-of-uniforms method. Statistics and Computing, 1, 129-133.
  97. Wakefield, J. C., Skene, A. M., Smith, A. F. M. and Evett, I. W. (1991). The evaluation of fibre transfer evidence in forensic science: a case study in statistical modelling. Applied Statistics, 40, 461-476.
  98. Skene, A. M., and Wakefield, J. C. (1990). Hierarchical models for multi-centre binary response studies. Statistics in Medicine, 9, 919-929.