Longitudinal Analysis of MMF Clinical, Molecular, and Immunohistochemistry (IHC) Responses Shows SSc Patients Lose Their Inflammatory Signature and Rebound upon Treatment Cessation

Monique Hinchcliff2*, Diana Toledo1*, Jaclyn Taroni1, Tammara A. Wood3, Jennifer M. Franks3, Sanjiv Shah4, Rishi Agrawal4, Lauren Beussink-Nelson4, Mary A. Carns5, Sofia Podlusky6, Patricia Pioli7 and Michael Whitfield3
1Department of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, 2Northwestern University, Feinberg School of Medicine Scleroderma Program, Chicago, IL, 3Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, 4Northwestern University, Chicago, IL, 5Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Northwestern University, Chicago, IL, 6Rheumatology Feinberg School of Medicine, Northwestern University, Chicago, IL, 7Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH; *Contributed Equally