The Smith Laboratory at the UW


Defensins are a family of antimicrobial peptides that are an evolutionarily conserved effector component of the innate immune response.  Although their antibacterial properties are well established in vitro and in vivo, their antiviral activity is less well understood.  The Smith Lab is interested in uncovering the molecular mechanisms by which defensins modulate non-enveloped viral infection and understanding the role of these molecules in viral pathogenesis in vivo.


Research Interests

Lab Address:

Department of Microbiology - Box 358070

South Lake Union F560

University of Washington

750 Republican St.

Seattle, WA 98109

Lab: 206-616-5649