PPT Slide

RNA polymerase

+

Core enzyme

Holoenzyme

• the function of s is to ensure that bacterial RNA polymerase binds in a

stable manner to DNA only at promoters, not at other sites

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A single type of RNA polymerase appears to be responsible for almost all synthesis of mRNA and all rRNA and tRNA in bacteria The complete enzyme is called holoenzyme. It is a large complex of MW ~465 kDa. The complex is a tetramer consisting of the fol