Lab Facilities and Environment:

A general laboratory suite of about 6000 ft² houses our group. This includes three laboratories set up for organic synthesis and three for biochemical and molecular genetic work, a fermentation area, a biochemical preparations room, an instrument room and a cold room.

Our major lab equipment support research on organic synthesis and molecular biology. These facilities include an IBM AF-300 NMR spectrometer, a Hewlett Packard GC-MS spectrometer, a Hewlett Packard UV spectrometer, 3 Beckman HPLCs, a Beckman P/Ace System 5010 capillary electrophoresis apparatus, 2 large scale Microferm fermentors, 2 controlled environmental shaker cabinets, a couple of culture shakers, an autoclave, a Beckman LS 1801 liquid scintillation counter, a French pressure cell press, a high vacuum corrosion resistant freeze-dryer (lyophilizer), a Sorvall refrigerated centrifuge, a Vavant high speed vacuum centrifuge, 4 eppordorf centrifuges, 3 peltier thermal cyclers, a hybridizing oven, and a number of horizontal and vertical electrophoresis apparatus.

Other useful research facilities and resources are within our reach. Chemistry Department NMR Clusters offer 200, 300, 500, 750 MHz NMR spectrometers. Chemistry Department Spectroscopic and Analytical Services provide broad range of analysis tools from EI, ES, FAB, GC and direct probe MS spectrometers to circular dichroism spectrophotometer, polarimeter, fluorescence spectrophotometer, FTIR Spectrophotometers, atomic absorption spectrophotometer, atomic emission spectrophotometer, liquid chromatograph and capillary gas chromatograph.

Also we have access to additional EI- and FAB MS/MS, LC-MS and high resolution FAB-MS spectrometers at the University Mass Spectrometry Center in the Department of Medicinal Chemistry. Gas-phase protein and peptide microsequencing, amino acid analysis and automated DNA sequencing are available from service facilities in the Pharmacology Department and Biochemistry Department.