Vol. 51, Issue 13
July 10, 2008 Cover

X-ray structure of a 2-oxotetrahydroquinoline-based inhibitor bound to the protein farnesyltransferase from the malaria parasite (Plasmodium falciparum) (farnesyl in cyan, diphosphate in red, and Zn2+ in green) (Bulbule, V. J.; et al. J. Med. Chem. 2008, 51, 384−387).