Stat 593A Schedule of lectures

Spring 2004

THIS SCHEDULE IS PRELIMINARY, AND SUBJECT TO CHANGE

Date
Topic
References and remarks
Wednesday, March 31 Gene descent in pedigrees
Meiosis indicators and recombination.
Friday, April 2 Genetic models and inference problems
Models for Meiosis.
My book: Chapter 5.
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Wednesday, Apr 7 Tetrads, chromatids and Mather's formula.
The chaismata avoidance function
Speed & Waterman Pp. 65-88: "What is a map function?".
Friday, Apr 9 Count-location meiosis models
Renewal process chiasmata models
Lange Chapter 12: "Models for meiosis"
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Wednesday, Apr 14 Peeling: sums on graphs
Baum algorithm for likelihoods
Peeling the FGL graph
Book 6.1, 6.2
Japan paper (2003)
Friday, Apr 16 Peeling on pedigree structures.
3.30: UW Science Forum
Book 6.3, 6.4
Garry Odell speaking on Gene networks at 3.30 p.m.
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Wednesday, Apr 21 NO CLASS: I am in Minnesota Plan your presentations
Friday, Apr 23 NO CLASS: I am in Minnesota Plan your presentations
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Wednesday, Apr 28 Peeling for likelihoods on pedigrees, ctd.
Reverse peeling in an HMM
Book: 6.5, 6.6, 7.1
Friday, Apr 30 Monte Carlo reverse peeling
Pedigree risk probabilities etc.
Ting-Yuan : Browning (2000): interference
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Wednesday, May 5 Monte Carlo likelihood
Sequential imputation
Book: 7.3, 7.6
Friday, May 7 I-Yu Chiu : Elston,Sobel (1979) Ascertainment
Saonli Basu: Kruglyak (1998) FTT for HMMs
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Wednesday, May 12 MCMC on pedigrees
MCMC estimates of lod-scores
Book: Ch 8, 9.1, 9.5
Friday, May 14 Haoyuan Zhu : Excoffier, Slatkin (1995): EM for haplotypes
Grace Ge : Stephens, PHASE; Bayes for haplotypes
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Wednesday, May 19 Integrated proposals and joint updating
Pseudo-Bayes estimation of lod scores
New stuff! George and Thompson, Statist. Sci. Nov 2003
Friday, May 21 Arindam RoyChoudhury: Donnelly (1986): urn models and Ewens sampling formula
Paul Scheet: Pritchard et al.: Population structure
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Wednesday, May 26 Metropolis-Hastings; sequential imputation, reweighting
Examples of MCMC lod score estimation??
Friday, May 28 Caroline Cutting: Zhao,McPeek, Speed: Chromatid interference
Bill Stewart: map estimation using MCMC
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Wednesday, Jun 2 Examples of MCMC lod score estimation?? (ctd)
MCMC for general meiosis models
Book: Chapter 11.
Friday, Jun 4 Garrett Hellenthal: Thomas/Gutin; advances MCMC on pedigrees
Joe Rothstein: Sequential imputation on pedigrees
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