| 356 BCE | Born to Philip of Macedonia |
| 343 | Aristotle becomes his tutor |
| 336 | Becomes king of Macedonia |
| 334 | Crosses to Asia Minor |
| 333 | Defeats Persians under Darius at Issus |
| 332 | Crowned pharaoh at Memphis in Egypt |
| 331 | Defeats Persians at Guagamela |
| 330 | Sacks Persian capital Persepolis |
| 329 | Crosses Oxus R. into Central Asia and reaches Samarkand (Maracanda) |
| 327 | Begins invasion of India |
| 326 | Reaches Taxila |
| 323 | Death in Babylon |