We characterized a cyclic nucleotide-gated ion channel using cryoEM to yield new insights about the mode of action of this medically important channel family.
We identified and characterized type VI secretion system effectors promoting Francisella growth in macrophages.
Our atomic resolution structure of a human coronavirus spike protein highlights strategies used by these viruses to evade the immune system.
We used cryoEM to determine the first structure of a coronavirus spike glycoprotein at near-atomic resolution.
The cryoEM reconstruction of the proteasome at 2.8 Å resolution enables identifying amino-acid side chains rotamers and resolving ordered water molecules.