50. "Fresnel diffraction theory for steady-state thermal lens measurements in thin films" S. Wu and N.J. Dovichi, Journal of Applied Physics 67, 1170-1182 (1990).
51. "Interaction of capillary zone electrophoresis with a sheath flow cuvette detector" Y.F. Cheng, S. Wu, D.Y. Chen, and N.J. Dovichi, Analytical Chemistry 62, 496-503 (1990).
52. "Capillary zone electrophoresis separation and laser-based detection of both fluorescein thiohydantoin and dimethylaminoazobenzene thiohydantoin derivatives of amino acids" K.C. Waldron, S. Wu, C.W. Earle, H.R. Harke, and N.J. Dovichi, Electrophoresis 11, 777-780 (1990).
53. "Capillary gel electrophoresis for DNA sequencing: laser-induced fluorescence detection with the sheath flow cuvette" H.P. Swerdlow, S. Wu , H.R. Harke, and N.J. Dovichi, Journal of Chromatography 516, 61-67 (1990).
54. "Spatially resolved differential resistance of bulk superconductors by laser-induced heating" R. McLaren and N.J. Dovichi, Journal of Applied Physics 68, 4882-4 (1990).
55. "Laser-based microchemical analysis" N.J. Dovichi, Review of Scientific Instruments 61, 3653-7 (1990).
56. "Three DNA sequencing methods using capillary gel electrophoresis and laser-induced fluorescence" H. Swerdlow, J.Z. Zhang, D.Y. Chen, H.R. Harke, R. Grey, S. Wu, C. Fuller, and N.J. Dovichi, Analytical Chemistry 63, 2835-41 (1991).
57. "Low-cost, high sensitivity laser-induced fluorescence detection for DNA sequencing by capillary gel electrophoresis" D.Y. Chen, H.P. Swerdlow, H.R. Harke, J.Z. Zhang, and N.J. Dovichi, Journal of Chromatography 559, 237-246 (1991).
58. "High-sensitivity laser-induced fluorescence detection for capillary electrophoresis" J.Z. Zhang, D.Y. Chen, S. Wu, H.R. Harke, and N.J. Dovichi, Clinical Chemistry 37, 1492-1496 (1991).
59. "DNA sequencing by capillary gel electrophoresis and laser-induced fluorescence detection" J.Z. Zhang, D.Y. Chen, H.R. Harke, and N.J. Dovichi, Analytical Sciences 7, 1485-1489 (1991).
60. "Attomole determination of phenyl thiohydantoin derivatives of amino acids by capillary zone electrophoresis separation and ultraviolet-laser excited thermo-optical absorbance detection" K.C. Waldron, J. Miller, and N.J. Dovichi, Analytical Sciences 7, 959-961 (1991).
61. "Sub-femtomole analysis of phenylthiohydantoin-amino acids: capillary electrophoresis and thermooptical detection" K.C. Waldron and N.J. Dovichi, Analytical Chemistry 64, 1396-1399 (1992).
62. "Capillary zone electrophoresis separation and laser induced fluorescence detection of zeptomole quantities of fluorescein thiohydantoin derivatives of amino acids" S. Wu and N.J. Dovichi, Talanta 39, 173-178 (1992).
63. "Formamide modified polyacrylamide gels for DNA sequencing by capillary gel electrophoresis" M.J. Rocheleau, R.J. Grey, D.Y. Chen, H.R. Harke, and N.J. Dovichi, Electrophoresis 13, 484-486 (1992).
64. "Stability of capillary gels for automated sequencing of DNA" H. Swerdlow, K.E. Dew-Jager, K. Brady, R. Gesteland, R. Grey, and N.J. Dovichi, Electrophoresis 13, 475-483 (1992).
65. "Effect of total percent polyacrylamide in capillary gel electrophoresis for DNA sequencing of short fragments: A Phenomenological Model" H.R. Harke, S. Bay, J.Z. Zhang, M.J. Rocheleau, and N.J. Dovichi, Journal of Chromatography 608, 143-150 (1992).
66. "Attachment of a single fluorescent label to peptides for determination by capillary zone electrophoresis" J.Y. Zhao, K.C. Waldron, J. Miller, J.Z. Zhang, H.R. Harke, and N.J. Dovichi, Journal of Chromatography 608, 239-242 (1992).
67. "Low-cost laser-induced fluorescence detector for micellar capillary zone electrophoresis: detection at the zeptomol level of tetramethylrhodamine thiocarbamyl amino acid derivatives" J.Y. Zhao, D.Y. Chen, and N.J. Dovichi, Journal of Chromatography 608, 117-120 (1992).
68. "Separation of DNA sequencing fragments at 53 bases/minute by capillary gel electrophoresis" M.J. Rocheleau and N.J. Dovichi, Journal of Microcolumn Separations 4, 449-453 (1992).
69. "Two-label peak-height encoded DNA sequencing by capillary gel electrophoresis: three examples" D.Y. Chen, H.R. Harke, and N.J. Dovichi, Nucleic Acids Research 20, 4873-4880 (1992).
70. "High-efficiency filter fluorometer for capillary electrophoresis and its application to fluorescein thiocarbamyl amino acids" E. Arriaga, D.Y. Chen, X. Cheng, and N.J. Dovichi, Journal of Chromatography 652, 347-353 (1993).
71. "Use of a sheath flow cuvette for chemiluminescence detection of isoluminol thiocarbamyl-amino acids separated by capillary electrophoresis" J.Y. Zhao, J. Labbe, and N.J. Dovichi, Journal of Microcolumn Separations 5, 331-339 (1993).
72. "Mobility of single-stranded DNA as a function of cross-linker concentration in polyacrylamide capillary gel electrophoresis" D. Figeys and N.J. Dovichi, Journal of Chromatography 645, 311-317 (1993).
73. "Behavior of microscopic liquid droplets near a strong electrostatic field: droplet electrospray" D.B. Hager and N. J. Dovichi, Analytical Chemistry 66, 1593-1594 (1994).
74. "Detection of 100 molecules of product formed in a fucosyltransferase reaction" J.Y. Zhao, N.J. Dovichi, O. Hindsgaul, S. Gosselin, and M.M. Palcic, Glycobiology 4, 239-242 (1994).
75. "Yoctomole detection limit by laser-induced fluorescence in capillary electrophoresis" D.Y. Chen and N.J. Dovichi, Journal of Chromatography 657, 265-269 (1994).
76. "Use of the fluorescent intercalating dyes POPO-3, YOYO-3 and YOYO-1 for ultrasensitive detection of double stranded DNA separated by capillary electrophoresis with hydroxypropylmethyl cellulose and non-cross-linked polyacrylamide" D. Figeys, E. Arriaga, A. Renborg, and N.J. Dovichi, Journal of Chromatography 669, 205-216 (1994).
77. "Separation of aminated monosaccharides by capillary zone electrophoresis with laser-induced fluorescence detection" J.Y. Zhao, P. Diedrich, Y. Zhang, O. Hindsgaul, and N.J. Dovichi, Journal of Chromatography 657, 307-313 (1994).
78. "A simple laser-induced fluorescence detector for sulforhodamine 101 in a capillary electrophoresis system: detection limits of 10 yoctomoles or six molecules" D.Y. Chen, K. Adelhelm, X.L. Cheng and N.J. Dovichi, The Analyst 119, 349-352 (1994).
79. "Effect of acetonitrile in the sampling solution on the analyte peak shape in micellar electrokinetic capillary chromatography" H.J. Crabtree, I. Ireland, and N.J. Dovichi, Journal of Chromatography 669, 263-267 (1994).
80. "High-speed and high-accuracy DNA sequencing by capillary gel electrophoresis in a simple, low cost instrument: two-color peak-height encoded sequencing at 40o C" H. Lu, E. Arriaga, D.Y. Chen, H. Starke, and N.J. Dovichi, Journal of Chromatography 680, 497-501 (1994).
81. "Activation energy of single stranded DNA moving through cross-linked polyacrylamide gels at 300 V/cm: effect of temperature on sequencing rate in high-electric-field capillary gel electrophoresis" H. Lu, E. Arriaga, D.Y. Chen, D. Figeys and N.J. Dovichi, Journal of Chromatography 680, 503-510 (1994).
82. "Separation of fragments up to 570 bases in length by use of 6% T non-cross-linked polyacrylamide for DNA sequencing in capillary electrophoresis" N. Best, E. Arriaga, D.Y. Chen, and N.J. Dovichi, Analytical Chemistry 66, 4063-4067 (1994).
83. "Internal fluorescence labeling with fluorescent deoxynucleotides in two-label peak-height encoded DNA sequencing by capillary electrophoresis" H.R. Starke, J.Y. Yan, J.Z. Zhang, K. Muhlegger, and N.J. Dovichi, Nucleic Acids Research 22, 3997-4001 (1994).
84. "High-sensitivity analysis of PTH amino acids", N.J. Dovichi, K.C. Waldron, M. Chen, and I. Ireland, Journal of Protein Chemistry 13, 470-471 (1994).
85. "Capillary gel electrophoresis for DNA sequencing of a template from the malaria genome by use of 4% T, 5% C polyacrylamide and two-color peak-height encoded fluorescence detection" S. Bay, H. Starke, J.Z. Zhang, J.F. Elliott, L.D. Coulson, and N.J. Dovichi, Journal of Capillary Electrophoresis 1, 121-126 (1994).
86. "Labeling of double-stranded DNA by ROX-dideoxycytosine triphosphate using terminal deoxynucleotidyl transferase and separation by capillary electrophoresis" D. Figeys, A. Renborg, and N.J. Dovichi, Analytical Chemistry 66, 4382-4383 (1994).
87. "Micellar capillary electrophoresis separation and thermo-optical absorbance detection of products from manual peptide sequencing" M. Chen, K.C. Waldron, Y.W. Zhao and N.J. Dovichi, Electrophoresis 15, 1290-1294 (1994).
88. "Droplet electrospray mass spectrometry" D.B. Hager, N.J. Dovichi, J. Klassen, P. Kebarle, Analytical Chemistry 66, 3944-3949 (1994).
89. "Spatial and temporal depletion of ions from noncrosslinked denaturing polyacrylamide in capillary electrophoresis" D. Figeys, A. Renborg, and N.J. Dovichi, Electrophoresis 15, 1512-1517 (1994).
90. "The use of 3-(p-Carboxybenzoyl)-Quinoline-2-Carboxaldehyde (CBQ) to label amino acids for high sensitivity fluorescence detection in capillary electrophoresis" E.A. Arriaga, Y. Zhang, and N.J. Dovichi, Analytica Chimica Acta 299, 319-326 (1995).
91. "Fluorescence-based enzymatic assay by capillary electrophoresis laser-induced fluorescence detection for the determination of a §-galactosidase molecules" D. Craig, E.A. Arriaga, P. Banks, Y. Zhang, A. Renborg, M.M. Palcic, and N.J. Dovichi, Analytical Biochemistry 226, 147-153 (1995).
92. "Solid-phase fluorescent labeling reaction of picomole amounts of insulin in very dilute solutions and their analysis by capillary electrophoresis" D.M. Pinto, E.A. Arriaga, S. Sia, Z. Li, and N.J. Dovichi, Electrophoresis 16, 534-540 (1995).
93. "Monitoring biosynthetic transformations of n-acetyl lactosamine using fluorescently labeled oligosaccharides and capillary electrophoretic separation" Y. Zhang, X.C. Le, N.J. Dovichi, C.A. Compston, M.M. Palcic, P. Diedrich, and O. Hindsgaul, Analytical Biochemistry 227, 368-376 (1995).
94. "Nanomolar determination of aminated sugars by capillary electrophoresis" Y. Zhang, E. Arriaga, P. Diedrich, O. Hindsgaul, and N.J. Dovichi, Journal of Chromatography 716, 221-229 (1995).
95. "Analysis by capillary electrophoresis laser induced fluorescence detection of oligosaccharides produced from enzyme reactions" X.C. Le, C. Scaman, Y. Zhang, J.Z. Zhang, N.J. Dovichi, O. Hindsgaul and M.M. Palcic, Journal of Chromatography 716, 215-220 (1995).
96. "Effect of the age of non-cross-linked polyacrylamide on the separation of DNA sequencing samples" D. Figeys and N.J. Dovichi, Journal of Chromatography 717, 105-111 (1995).
97. "Multiple separations of DNA sequencing fragments with a non-cross-linked polyacrylamide-filled capillary: capillary electrophoresis at 300 V/cm" D. Figeys and N.J. Dovichi, Journal of Chromatography 717, 113-116 (1995).
98. "The biosynthesis of Lewis X in Helicobacter pylori" N.W.C. Chan, K. Stangier, R. Sherburne, D.E. Taylor, Y.N. Zhang, N.J. Dovichi, and M.M. Palcic, Glycobiology 5, 683-688 (1995).
99. "Use of non-cross-linked polyacrylamide for four-color DNA sequencing by capillary electrophoresis separation of fragments up to 640 bases in length in two hours" J.Z. Zhang, Y. Fang, J.Y. Hou, H.J. Ren, R. Jiang, P. Roos, and N.J. Dovichi, Analytical Chemistry 67, 4589-4593 (1995).
100. "Single-molecule detection in capillary electrophoresis: molecular shot noise as a fundamental limit to chemical analysis" D.Y. Chen and N.J. Dovichi, Analytical Chemistry 68, 690-696 (1996).
101. "Detection of attomolar concentrations of alkaline phosphatase by capillary electrophoresis using laser-induced fluorescence detection" D.B. Craig, J.C.Y. Wong, and N.J. Dovichi, Analytical Chemistry 68, 697-700 (1996).
102. "The limiting mobility of DNA sequencing fragments for both cross-linked and noncross-linked polymers in capillary electrophoresis: DNA sequencing at 1200 Vcm-1" J.Y. Yan, N. Best, J.Z. Zhang, H.J. Ren, R. Jiang, J. Hou, and N.J. Dovichi, Electrophoresis 17, 1037-1045 (1996).
103. "Studies on single alkaline phosphatase molecules: reaction rate and activation energy of a reaction catalyzed by a single molecule and the effect of thermal denaturation-The death of an enzyme." D.B. Craig, E. Arriaga, J.C.Y. Wong, H. Lu, and N.J. Dovichi, Journal of the American Chemical Society 118, 5245-5253 (1996).
104. "Pseudo-coulometric loading in capillary electrophoresis DNA sequencing" D. Figeys, H. Ahmadzedeh, E. Arriaga, and N.J. Dovichi, Journal of Chromatography 744, 325-331 (1996).
105. "Change in conductivity in non-cross-linked polyacrylamide capillary electrophoresis: effects of aging polyacrylamide and buffer composition" D. Figeys and N.J. Dovichi, Journal of Chromatography 744, 333-339 (1996).
106. "Activation energy of separation of DNA sequencing fragments in denaturing non-crosslinked polyacrylamide by capillary electrophoresis" Y. Fang, J.Z. Zhang, J.Y. Hou, H. Lu, and N.J. Dovichi, Electrophoresis 17, 1436-1442 (1996).
107. "Use of a solid phase to label peptide toxins with fluorescent labels and ultrasensitive determination based on capillary-tube electrophoresis" D. Pinto, E. Arriaga, S. Sia, Z. Li, N.J. Dovichi, Ing. Cienc. Quim. 16, 28-29 (1996).
108. "Miniaturized protein microsequencer with PTH identification by capillary electrophoresis I. An argon pressurized delivery system for adsorptive and covalent sequencing" K.C. Waldron, X.F. Li, M. Chen, I. Ireland, D. Lewis, M. Carpenter, and N.J. Dovichi, Talanta 44, 383-399 (1997).
109. "Miniaturized protein microsequencer with PTH identification by capillary electrophoresis II. A syringe-pump-based system for covalent sequencing" X.F. Li, K.C. Waldron, J. Black, D. Lewis, I. Ireland, and N.J. Dovichi, Talanta 44, 401-411 (1997).
110."Detection of Aequorea victoria green fluorescent protein by capillary electrophoresis laser induced fluorescence detection" D.B. Craig, J.C.Y. Wong and N.J. Dovichi, Biomedical Chromatography 11, 205-206 (1997).
111. "Picomolar assay of native proteins by capillary electrophoresis - precolumn labeling, sub-micellar separation, and laser induced fluorescence detection" D.M. Pinto, E.A. Arriaga, D. Craig, J. Angelova, N. Sharma, H. Ahmadzadeh, N.J. Dovichi, C.A. Boulet, Analytical Chemistry 69, 3015-3021 (1997).
112. "Study of enzymatic transformation of fluorescently labeled oligosaccharides in human epidermoid cells using capillary electrophoresis with laser induced fluorescence detection" X. C. Le, Y. Zhang, N.J. Dovichi, C.A. Compston, M.M. Palcic, and O. Hindsgaul, Journal of Chromatography 781, 515-522 (1997).
113. "Double coupling Edman chemistry for high-sensitivity automated protein sequencing" I.D. Ireland, D.F. Lewis, X.F. Li, A. Renborg, S. Kwong, M. Chen, and N.J. Dovichi, Journal of Protein Chemistry 16, 491-495 (1997).
114."The physics of the genome program" N.J. Dovichi, Physics World 10, (September) 41-45 (1997) also published on the web .
115. "DNA sequencing by capillary electrophoresis" N.J. Dovichi, Electrophoresis 18, 2393-2399 (1997).
116. "Free-solution electrophoresis of DNA" C. Heller, G.W. Slater, P. Mayer, N. Dovichi, D. Pinto, J.L. Viovy, and G. Drouin, Journal of Chromatography 806, 113-121 (1998).
117. "The life and death of a single enzyme molecule" D.B. Craig, E. Arriaga, J.C.Y. Wong, H. Lu, and N.J. Dovichi, Analytical Chemistry 70, 39A-43A (1998).
118. "SDS-capillary electrophoresis of proteins in a sieving matrix utilizing two-spectral channel laser-induced fluorescence detection" D.B. Craig, R. Polakowski, J.C.Y. Wong, H. Ahmadzadeh, C. Stathakis and N.J. Dovichi, Electrophoresis 19, 2175-2179 (1998).
119. "E. coli b-galactosidase is heterogeneous with respect to the activity of individual molecules" D.B. Craig and N.J. Dovichi, Canadian Journal of Chemistry 76, 623-626 (1998).
120. "Multiple labeling of proteins" D.B. Craig and N.J. Dovichi, Analytical Chemistry 70, 2493-94 (1998).
121. "Combating PCR bias in bisulfite-based cytosine methylation analysis - betaine modified cytosine deamination PCR" K.O. Voss, K.P. Roos, R.L. Nonay and N.J. Dovichi, Analytical Chemistry 70, 3818-3823 (1998).
122. "General protease assay method coupling solid phase substrate extraction and a separation method to enhance sensitivity and selectivity" D.B. Craig, J.C.Y. Wong, R. Polakowski and N.J. Dovichi, Analytical Chemistry 70, 3824-3827 (1998).
123. "Cationic and anionic polymeric additives for wall deactivation and selectivity control in the capillary electrophoretic separation of proteins in food samples" C. Stathakis, E.A. Arriaga, D.F. Lewis, and N.J. Dovichi, Journal of Chromatography 817, 227-232 (1998).
124. "Protein profiling employing capillary electrophoresis with dendrimers as pseudostationary phase media" C. Stathakis, E.A. Arriaga, and N.J. Dovichi, Journal of Chromatography 817, 233-238 (1998).
125. "Capillary Electrophoretic Separation of Polynuclear Aromatic Hydrocarbons using Sodium Cholate in Mixed Aqueous/Organic Buffers" H. Ren, X. Li, M. Qi, C. Stathakis, and N.J. Dovichi, Journal of Chromatography 817, 307-312 (1998).
126. "Picomolar analysis of proteins using electrophoretically mediated microanalysis and capillary electrophoresis with laser induced fluorescence detection" I.H. Lee, D. Pinto, E.A. Arriaga, Z. Zhang, N.J. Dovichi, Analytical Chemistry 70, 4546-4548 (1998).
127. "Nonaqueous capillary electrophoretic separation and thermo-optical absorbance detection of five tricyclic antidepressants and metabolism of amitriptyline by Cunninghamella elegans" X.F. Li, C.S. Liu, P. Roos, E.B. Hansen, C.E. Cerniglia, and N.J. Dovichi , Electrophoresis 19, 3178-3182 (1998).
128. On-line nonaqueous capillary electrophoresis and electrospray mass spectrometry of tricyclic antidepressants and metabolic profiling of amitriptyline with Cunninghamella elegans" C.S. Liu, X.F. Li, D. Pinto, E.B. Hansen, C.E. Cerniglia, and N. J. Dovichi, Electrophoresis 19, 3183-3189 (1998).
129. "Surface modification based on Si-O and Si-C sub-layers and a series of N-substituted acrylamide top-layers for capillary electrophoresis" C. Gelfi, M. Curcio, P.G. Righetti, R. Sebastiano, A. Citterio, H. Ahmadzadeh, and N.J. Dovichi, Electrophoresis 19, 1677-1682 (1998).
130. "Single cell studies of enzymatic hydrolysis of a tetramethylrhodamine labeled trisaccharide in yeast" X.C. Le, W. Tan, C. Scaman, A. Szpacenko, E. Arriaga, Y. Zhang, N.J. Dovichi, O. Hindsgaul and M.M. Palcic, Glycobiology 9, 219-225 (1999).
131. "Species identification and phylogenetic relationships based on partial HSP60 gene sequences within the genus Staphylococcus" A.Y.C. Kwok, S.C. Su, R.P. Reynolds, S.J. Bay, Y. Av-Guy, N.J. Dovichi, and A.W. Chow, The International Journal of Systematic Bacteriology 49, 1181-1192, (1999).
132. "Correlating cell cycle with metabolism in single cells: the combination of image and metabolic cytometry" S.N. Krylov, Z. Zhang, N.W. C. Chan, E. Arriaga, M.M. Palcic, and N.J. Dovichi, Cytometry 37, 15-20 (1999).
133. "Labeling Effects on the Isoelectric Point of Green Fluorescent Protein" D. Richards, C. Stathakis, R. Polakowski, H. Ahmadzadeh, and N.J. Dovichi, Journal of Chromatography A 853, 21-25 (1999).
134. "Detection of Duck Hepatitis B Virus DNA Fragments using On-Column Intercalating Dye Labeling with Capillary Electrophoresis -Laser Induced Fluorescence (CE-LIF)" W.G. Tan, L. Tyrell, and N.J. Dovichi, Journal of Chromatography A 853, 309-319 (1999).
135. "Capillary Electrochromatography with Thermo-Optical Absorbance Detection for the analysis of phenylthiohydantoin amino acids" M. Qi, X.F. Li, C. Stathakis, and N.J. Dovichi, Journal of Chromatography A 853, 131-140 (1999).
136. "Development of DNA sequencer" N. Dovichi, Science 285, 1016 (1999).
back to top
