Selected
Publications on Translational Control
Degen, J. L., Neubauer, M. G., Degen, S. J. F., Seyfried, C. E., and Morris, D. R. Regulation of Protein Synthesis in Mitogen-Activated Bovine Lymphocytes. Analysis of Actin Specific and Total mRNA Accumulation and Utilization. J. Biol. Chem. 258, 12153-12162 (1983).
Mach, M., White, M. W., Degen, J. L., Neubauer, M., and Morris, D. R. Isolation of a cDNA Clone Encoding S-Adenosylmethionine Decarboxylase. Expression of the Gene in Mitogen-Activated Lymphocytes. J. Biol. Chem. 261, 11697-11703 (1986). [Abstract]
White, M. W., Kameji, T., Pegg, A. E., and Morris, D. R. Increased Efficiency of Translation of Ornithine Decarboxylase mRNA in Mitogen-Activated Lymphocytes. Eur. J. Biochem. 170, 87-92 (1987). [Abstract ]
Kaspar, R. L., Rychlik, W., White, M. W., Rhoads, R. E., and Morris, D. R. Simultaneous Cytoplasmic Redistribution of Ribosomal Protein L32 mRNA and Phosphorylation of eIF-4E after Mitogenic Stimulation of Swiss 3T3 Cells. J. Biol. Chem. 265, 3619-3622 (1990).
White, M. W., Degnin, C., Hill, J., and Morris, D. R. Specific Regulation by Endogenous Polyamines of Translational Initiation of S-Adenosylmethionine Decarboxylase mRNA in Swiss 3T3 Fibroblasts. Biochem. J. 268, 657-660 (1990).
Kaspar, R. L., Kakegawa, T.,
Hill, J. R., and Morris, D. R. Cell-Specific Translation of S-Adenosylmethionine Decarboxylase mRNA. Regulation by the 5' Transcript Leader. J. Biol. Chem. 267, 21886-21893 (1992). [Abstract]
Hill, J. R., and Morris, D. R. Cell-Specific Translation of
S-Adenosylmethionine Decarboxylase mRNA. Dependence on Translation and Coding
Capacity of the Cis-Acting Upstream Open
Kaspar, R. L., Morris, D. R., and White, M. W. Control of Ribosomal
Protein Synthesis in Eukaryotic Cells. In Translational Regulation of Gene
Expression II (J. Ilan, ed.), Plenum Publishing Corp.,
Morris, D. R., Kakegawa, T., Kaspar, R., and White, M. W. Polypyrimidine Tracts and Their Binding Proteins: Regulatory Sites for Post-Transcriptional Modulation of Gene Expression. Biochemistry 32, 2931-2937 (1993).
Geballe, A. P., and Morris, D. R. Initiation Codons within 5'-Leaders of mRNAs as Regulators of Translation. Trends Biochem. Sci. 19, 159-164 (1994).
Ruan, H., Hill, J. R., Fatemie-Nainie, S., and Morris, D. R. Cell-Specific
Translational Regulation of S-Adenosylmethionine Decarboxylase mRNA: Influence
of the Structure of the 5' Transcript Leader on Regulation by the Upstream Open
Morris, D. R. Growth Regulation of Translation in Mammalian Cells. Prog. Nucl. Acids Res. Mol. Biol. 51, 339-363 (1995).
Ruan, H., Shantz, L. M., Pegg, A. E., and Morris, D. R. The Upstream Open
Morris, D. R. cis-Acting mRNA Structures in Gene-Specific Translational
Control. In Post-Transcriptional Gene Regulation (Harford, J. B., and
Morris, D. R., eds.), Wiley-Liss, Inc.,
Ruan, H., Brown, C. Y., and Morris, D. R. Analysis of
Ribosome Loading onto mRNA Species: Implications for Translational Control.
In mRNA Formation and Function (Richter, J. D., ed.), Academic Press,
Mize, G. J., Ruan, H., Low, J. J., and Morris, D. R. The Inhibitory
Upstream Open
Zong, Q., Schummer, M., Hood, L., and Morris, D. R.
Brown, C. Y., Mize, G. J., Pineda, M., George, D. L., and Morris, D.
R. Role of Two Upstream Open
in the Translational Control of Oncogene mdm2. Oncogene 18,
5631-5637 (1999). [Abstract]
Raney, A., Baron, A. C., Mize, G. J., Law, G. L., and Morris, D. R. In
Vitro Translation of the Upstream Open
Morris, D. R., and Geballe, A. P. Upstream Open
Mize, G. J., and Morris, D. R. A Mammalian Sequence-Dependent Upstream
Open
Law, G. L., Raney, A., Heusner, C. and Morris, D R. Polyamine
Regulation of Ribosome Pausing at the Upstream Open
Raney, A.., Law, G. L., Mize, G. J., and Morris, D. R. Regulated Translation Termination at
the Upstream Open
Serikawa, K.A., X.L.Xu, V.L.MacKay, G.L.Law, Q.Zong, L.P.Zhao, R.Bumgarrner, and D.R.Morris. The transcriptome and its translation during recovery from cell-cycle arrest in Saccharomyces cerevisiae. Mol. Cell. Proteomics 2:191-204. (2003).
Jin, X., E.Turcott, S.Englehardt, G.J.Mize, and D.R.Morris. The two upstream open reading frames of oncogene mdm2 have different translational regulatory properties. J. Biol. Chem. 278:25716-25721 (2003).
MacKay, V.L., X.Li, M.R.Flory, E.Turcott, G.L.Law, K.A.Serikawa, X.L.Xu, H.Lee, D.R.Goodlett, R.Aebersold, L.P.Zhao, and D.R.Morris. Gene expression in yeast responding to mating pheromone: Analysis by high-resolution translation state analysis and quantitative proteomics. Mol. Cell. Proteomics 3:478-489 (2004).
Law, G.L., Bickel, K.S., MacKay, V.L., and Morris, D.R. The Under-Translated Transcriptome Reveals Widespread Translational Silencing by Alternative 5’ Transcript Leaders. Genome Biol. 6, R111 (2005).
Bickel, K.S.and Morris, D.R. Silencing the transcriptome's dark matter: mechanisms for suppressing translation of intergenic transcripts. Mol. Cell 22, 309-316 (2006).
Bickel, K.S.and Morris, D.R. Role of the transcription activator, Ste12p,
as a repressor of PRY3 expression. Mol. Cell. Biol. 26, 7901-7912 (2006).
Flory,M.R., Lee,H., Bonneau,R., Mallick,P., Serikawa,K., Morris,D.R., and Aebersold,R. Quantitative proteomic analysis of the budding yeast cell cycle using acid-cleavable isotope-coded affinity tag reagents. Proteomics. 6, 6146-6157 (2006).
Fox, R., Nhan, T.Q., Law, G.L., Morris, D.R., Liles, W.C., and Schwartz, S.M. mTOR-mediated translational control of ROCK-1 is a pivotal control point in the activation of macrophages. EMBO J. 26, 505-515 (2007).
Skjondal-Bar, N. and Morris, D.R. Dynamic Model of the Process of Protein Synthesis in Eukaryotic Cells. Bull. Math. Biol., 69, 361-93 (2007).
Sampath, S., Pritchard, D.K., Pabon, L, Reinecke, H., Schwartz, S.M., Morris, D.R., Murry, C.E. A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation. Cell Stem Cell, 2, 448-460 (2008).
Morris, D.R. Ribosomal footprints on a transcriptome landscape. Genome Biol. 10, 215 (2009).
Sanz, E., Yang, L., Su, T., Morris, D.R., McKnight, G.S., and Amieux, P.S. Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. Proc.Natl.Acad.Sci.U.S.A. 106, 13939-13944 (2009).
Schaeffer, V., Hansen, K.M., Morris, D.R., and Abrass, C.K. Reductions in laminin b2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose. Am. J. Physiol. 298, F314-F322 (2010).
