About Me

I am a postdoc in Jay Shendure's lab where I am developing genomic technologies to better understand gene regulation. I received my PhD in 2014 from the University of Chicago where I worked in Yoav Gilad's lab. I am broadly interested in gene regulation in humans. My particular research projects have included studying how genetic variants associated with asthma-relevant quantitative traits influence gene expression, how perturbing transcription factor interactions with the genome influences downstream gene expression networks, and (most recently) I have developed an assay for measuring chromatin accessibility at single-cell resolution. Future questions I hope to pursue include:

  • Delineating the functional mechanisms by which variation in gene regulation leads to susceptibility to asthma and allergy
  • Better understanding the degree and impact of regulatory variation within human populations
  • Studying how regulatory variation gives rise to phenotypic differences between humans and other primates