|
|
|
||
|
|
|
|
|
P.I.
|
Agency
|
Type
|
Dates
|
Title
|
Description
|
|
Albert
Folch
|
NSF
(BES)
|
CAREER
Award
|
2/15/01 - 2/15/06 |
Microscale
Engineering of Cellular Environments
|
The
major goal of this project is to integrate in a microfabricated device
the central protocols of cell culture - cell seeding and cell feeding
- in order to enable high-throughput studies at scales down to single
cells and small cell clusters.
|
|
Albert
Folch
|
Washington
Technology Center & Micronics, Inc.
|
|
1/1/01 - 1/1/03 (completed) |
A
Combinatorial Micromixer
|
The
major goal of this project is to build a microfluidic device for combinatorial
dyeing of fibroblasts, as a test system for a future cell screening microdevice.
|
|
Albert
Folch
|
NIH
(NCRR)
|
R21:
Innovative Approaches to Developing New Technologies
|
8/1/01 - 7/1/03 (completed) |
Nanofluidic
Probes for Recording / Stimulating Cell Behavior
|
The
major goal of this project is to develop a technology that will allow
us to probe and modify nanometer-scale areas of the cell membrane surface
on large numbers of cultured cells simultaneously by seeding cells on
microarrays of nanofluidic apertures.
|
|
Albert
Folch
|
Whitaker
Foundation
|
Biomedical
Engineering Research Grant
|
5/1/01 - 5/1/04 (completed) |
Microarrays
of Cellular Membrane Patches for High-Throughput Studies of Ion Channel
Function
|
The
major goal of this project is to perform high-throughput studies of ion
channel function by immobilizing neuroblastoma cells and their cellular
membrane patches in an addressable microarray (complemented by NASA, see
below).
|
|
Albert
Folch
|
NASA
|
Cellular
and Macromolecular Biotechnology
|
9/1/01 - 3/1/05 |
Microarrays
of Cellular Membrane Patches for In-Flight Studies of Ion Channel Function
|
The
major goal of this project is to perform high-throughput studies of ion
channel function by immobilizing HEK293 cells and cellular membrane patches
in an addressable microarray (complemented by Whitaker, see above).
|
|
Albert
Folch
|
NIH
(NIBIB)
|
R21/R33:
Technology Development for Biomedical Applications
|
8/1/03 - 8/1/08 |
Combinatorial
Effects of Axon Guidance Molecules on Cultured Neurons
|
The
major goal of this project is to probe and quantitate combinatorial effects
of axon guidance molecules on the growth of axons in cultured embryonic
neurons.
|
|
Albert
Folch
|
NIH
(NIBIB)
|
R01:
Bioengineering Research Grant
|
8/1/03 - 8/1/08 |
A
Nanofluidic Device for Synaptogenesis Studies
|
The
major goal of this project is to ellicit early stages of synaptogenesis
in vitro by using a device that will focally deliver synaptogenic factors
to a submicron-sized area of the membrane of cultured muscle cells.
|
|
Albert
Folch
|
NIH
(NIDOCD)
|
R21:
Exploratory/ Developmental Research Grant
|
7/1/04 - 7/1/06 |
Deciphering
the Olfactory Code: High-Throughput Search for Matches Between Odorants
and Odorant Receptors
|
The
major goal of this project is to screen large numbers of olfactory neurons
in microarrays to find matches between a set of odorants and all the odorant
receptors using a microfluidic device.
|
|
Albert
Folch
|
Anonymous
Source
|
|
9/1/07 - 9/1/08 |
Molecular
Mechanisms of Synaptogenesis: Studies of the Neuromuscular Junction Using
Microfluidics
|
The
major goal of this project is to study the interactions between agrin
and neuregulin using a microfluidic model of synaptogenesis and cultured
myotubes.
|
|
|
Aside from these sources of funding, lab members have received fellowships from a variety of sources, including UW's Nanotechnology Center (Anna Tourovskaia, Tom Keenan, Chihchen Chen, Fettah Kosar, and Aileen Wu), Department of Defense (Jackie Rettig), NIH's "Life at the Microscale" Training Grant (Greg Boggy), and NIH's UW Oral Biology Training Grant (Dr. Xavier Figueroa-Masot).
